未登录On-target mutations drive resistance to WRN helicase inhibitors in microsatellite unstable colorectal cancer
Picco, G.; Rao, Y.; Al Saedi, A.; Vieira, S.; Lee, Y.; Walker, S.; Bhosle, S.; May, K.; Taygerly, J.; Jones, B.; Coelho, M.; Houseley, J.; Sharma, G.; Schwartz, B.; Garnett, M.
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收藏Novel WRN helicase inhibitors selectively target microsatellite unstable cancer cells
Picco, Gabriele; Rao, Yanhua; Al Saedi, Angham; Vieira, Sara F.; Lee, Yang; Shenje, Ray; Bhosle, Shriram; Walker, Samantha; May, Kieron; Herranz-Ors, Carmen; Dicer, Cansu; Gibson, Freddy; Banerjee, Ruby; Werner, Thilo; Cottom, Josh; Peng, Yang; Deng, Nanhua; Landis, Phil; Angel, Thomas; Bush, Jacob; Rees, Matthew G.; Ronan, Melissa M.; Roth, Jennifer A.; Lightfoot, Howard; Zappacosta, Francesca; Pettinger, Jonathan; Barthorpe, Syd; Eberl, Chris; Jones, Brian; Schneck, Jess; Murphy, Dennis; Taygerly, Josh; DeMartino, Mike; Coelho, Matthew; Houseley, Jon; Schwartz, Benjamin; Garnett, Mathew J.
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收藏A small-molecule inhibitor of WRN selectively kills MSI-H cancer cells and phenocopies WRN genetic defects
Rao, Yanhua; Srivatsan, Anjana; Liimatta, Marya; Munoz, Diana; Quirit, Jeanne; Shi, Jianxia; Nguyen, An; Xin Linghu; Federowicz, Federowicz; Jones, Brian; Fleury, Melissa; Newby, Zach; Dillon, Michael P.; Barsanti, Paul A.; Lackner, Mark R.; White, Michael A.; Lee, Yang; Landis, Phil; Peng, Yang; Cicchini, Michelle; Cottom, Josh; Nickels, Leng; Brnardic, Ed; DeMartino, Michael; Taygerly, Josh
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收藏The Arabidopsis LRR-RLK, PXC1, is a regulator of secondary wall formation correlated with the TDIF-PXY/TDR-WOX4 signaling pathway
Wang, Jiehua; Kucukoglu, Melis; Zhang, Linbin; Chen, Peng; Decker, Daniel; Nilsson, Ove; Jones, Brian; Sandberg, Goran; Zheng, Bo
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收藏Sl-IAA3, a tomato Aux/IAA at the crossroads of auxin and ethylene signalling involved in differential growth
Chaabouni, Salma; Jones, Brian; Delalande, Corinne; Wang, Hua; Li, Zhengguo; Mila, Isabelle; Frasse, Pierre; Latche, Alain; Pech, Jean-Claude; Bouzayen, Mondher
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收藏The tomato Aux/IAA transcription factor IAA9 is involved in fruit development and leaf morphogenesis
Wang, H; Jones, B; Li, ZG; Frasse, P; Delalande, C; Regad, F; Chaabouni, S; Latché, A; Pech, JC; Bouzayen, M
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收藏Down-regulation of DR12, an auxin-response-factor homolog, in the tomato results in a pleiotropic phenotype including dark green and blotchy ripening fruit
Jones, B; Frasse, P; Olmos, E; Zegzouti, H; Li, ZG; Latché, A; Pech, JC; Bouzayen, M
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