Duilio Cascio - Publications, H-index & Citations

Duilio Cascio

University of California Los Angeles

62H指数

255论文数

1.4W被引数

收录论文 66

发表时间

Structural evidence that RNA contributes to polymorphism of tau amyloid fibrils 结构证据表明RNA有助于tau淀粉样纤维的多态性

iScience

IF4.1

2026-03-26

OAAI

Romany Abskharon; Yi Xiao Jiang; Michael R. Sawaya; Peng Ge; Jeffrey Zhang; David R. Boyer; Joshua L. Dolinsky; Justin Pi; Duilio Cascio; Feng Guo; David S. Eisenberg

Cryo-EM structures of the D290V mutant of the hnRNPA2 low-complexity domain suggests how D290V affects phase separation and aggregation

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2024-02-01

OAAI

Lu, Jiahui; Ge, Peng; Sawaya, Michael R.; Hughes, Michael P.; Boyer, David R.; Cao, Qin; Abskharon, Romany; Cascio, Duilio; Tayeb-Fligelman, Einav; Eisenberg, David S.

Development and atomic structure of a new fluorescence-based sensor to probe heme transfer in bacterial pathogens

JOURNAL OF INORGANIC BIOCHEMISTRY

IF3.2

2023-12-01

OAAI

Mahoney, Brendan J.; Goring, Andrew K.; Wang, Yueying; Dasika, Poojita; Zhou, Anqi; Grossbard, Emmitt; Cascio, Duilio; Loo, Joseph A.; Clubb, Robert T.

Structure- based design of nanobodies that inhibit seeding of Alzheimer's patient-extracted tau fibrils

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2023-10-06

OAAI

Abskharon, Romany; Pan, Hope; Sawaya, Michael R.; Seidler, Paul M.; Olivares, Eileen J.; Chen, Yu; Murray, Kevin A.; Zhang, Jeffrey; Lantz, Carter; Bentzel, Megan; Boyer, David R.; Cascio, Duilio; Nguyen, Binh A.; Hou, Ke; Cheng, Xinyi; Pardon, Els; Williams, Christopher K.; Nana, Alissa L.; V. Vinters, Harry; Spina, Salvatore; Grinberg, Lea T.; Seeley, William W.; Steyaert, Jan; Glabe, Charles G.; Loo, Rachel R. Ogorzalek; Loo, Joseph A.; Eisenberg, David S.

Cryo-EM structure determination of small therapeutic protein targets at 3 Å-resolution using a rigid imaging scaffold 使用刚性成像支架在3å 分辨率下确定小治疗蛋白靶标的cryo-em结构

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2023-09-05

OAAI

Castells-Graells, Roger; Meador, Kyle; Arbing, Mark A.; Sawaya, Michael R.; Gee, Morgan; Cascio, Duilio; Gleave, Emma; Debreczeni, Judit E.; Breed, Jason; Leopold, Karoline; Patel, Ankoor; Jahagirdar, Dushyant; Lyons, Bronwyn; Subramaniam, Sriram; Phillips, Chris; Yeates, Todd O.

Low complexity domains of the nucleocapsid protein of SARS-CoV-2 form amyloid fibrils

NATURE COMMUNICATIONS

IF15.7

2023-04-25

OAAI

Tayeb-Fligelman, Einav; Bowler, Jeannette T.; Tai, Christen E. E.; Sawaya, Michael R.; Jiang, Yi Xiao; Garcia, Gustavo; Griner, Sarah L.; Cheng, Xinyi; Salwinski, Lukasz; Lutter, Liisa; Seidler, Paul M.; Lu, Jiahui; Rosenberg, Gregory M.; Hou, Ke; Abskharon, Romany; Pan, Hope; Zee, Chih-Te; Boyer, David R.; Li, Yan; Anderson, Daniel H.; Murray, Kevin A.; Falcon, Genesis; Cascio, Duilio; Saelices, Lorena; Damoiseaux, Robert; Arumugaswami, Vaithilingaraja; Guo, Feng; Eisenberg, David S.

The Shr receptor from Streptococcus pyogenes uses a cap and release mechanism to acquire heme-iron from human hemoglobin

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2023-01-24

OAAI

Macdonald, Ramsay; Mahoney, Brendan J.; Soule, Jess; Goring, Andrew K.; Ford, Jordan; Loo, Joseph A.; Cascio, Duilio; Clubb, Robert T.

Micro-electron diffraction structure of the aggregation-driving N terminus of Drosophila neuronal protein Orb2A reveals amyloid-like β-sheets

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2022-10-01

OAAI

Bowler, Jeannette T.; Sawaya, Michael R.; Boyer, David R.; Cascio, Duilio; Bali, Manya; Eisenberg, David S.

De novo determination of mosquitocidal Cry11Aa and Cry11Ba structures from naturally-occurring nanocrystals

NATURE COMMUNICATIONS

IF15.7

2022-07-28

OAAI

Tetreau, Guillaume; Sawaya, Michael R.; De Zitter, Elke; Andreeva, Elena A.; Banneville, Anne-Sophie; Schibrowsky, Natalie A.; Coquelle, Nicolas; Brewster, Aaron S.; Gruenbein, Marie Luise; Kovacs, Gabriela Nass; Hunter, Mark S.; Kloos, Marco; Sierra, Raymond G.; Schiro, Giorgio; Qiao, Pei; Stricker, Myriam; Bideshi, Dennis; Young, Iris D.; Zala, Ninon; Engilberge, Sylvain; Gorel, Alexander; Signor, Luca; Teulon, Jean-Marie; Hilpert, Mario; Foucar, Lutz; Bielecki, Johan; Bean, Richard; de Wijn, Raphael; Sato, Tokushi; Kirkwood, Henry; Letrun, Romain; Batyuk, Alexander; Snigireva, Irina; Fenel, Daphna; Schubert, Robin; Canfield, Ethan J.; Alba, Mario M.; Laporte, Frederic; Despres, Laurence; Bacia, Maria; Roux, Amandine; Chapelle, Christian; Riobe, Francois; Maury, Olivier; Ling, Wai Li; Boutet, Sebastien; Mancuso, Adrian; Gutsche, Irina; Girard, Eric; Barends, Thomas R. M.; Pellequer, Jean-Luc; Park, Hyun-Woo; Laganowsky, Arthur D.; Rodriguez, Jose; Burghammer, Manfred; Shoeman, Robert L.; Doak, R. Bruce; Weik, Martin; Sauter, Nicholas K.; Federici, Brian; Cascio, Duilio; Schlichting, Ilme; Colletier, Jacques-Philippe

Crystal structure of mevalonate 3,5-bisphosphate decarboxylase reveals insight into the evolution of decarboxylases in the mevalonate metabolic pathways

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2022-07-01

OAAI

Aoki, Mizuki; Vinokur, Jeffrey; Motoyama, Kento; Ishikawa, Rino; Collazo, Michael; Cascio, Duilio; Sawaya, Michael R.; Ito, Tomokazu; Bowie, James U.; Hemmi, Hisashi

The structure of the Clostridium thermocellum RsgI9 ectodomain provides insight into the mechanism of biomass sensing

PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

IF2.8

2022-02-28

OAAI

Mahoney, Brendan J.; Takayesu, Allen; Zhou, Anqi; Cascio, Duilio; Clubb, Robert T.

Insight into the molecular basis of substrate recognition by the wall teichoic acid glycosyltransferase TagA

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2022-02-01

OAAI

Martinez, Orlando E.; Mahoney, Brendan J.; Goring, Andrew K.; Yi, Sung-Wook; Tran, Denise P.; Cascio, Duilio; Phillips, Martin L.; Muthana, Musleh M.; Chen, Xi; Jung, Michael E.; Loo, Joseph A.; Clubb, Robert T.

Prospecting for natural products by genome mining and microcrystal electron diffraction

NATURE CHEMICAL BIOLOGY

IF13.7

2021-07-26

OAAI

Kim, Lee Joon; Ohashi, Masao; Zhang, Zhuan; Tan, Dan; Asay, Matthew; Cascio, Duilio; Rodriguez, Jose A.; Tang, Yi; Nelson, Hosea M.

CryoEM structure of the low-complexity domain of hnRNPA2 and its conversion to pathogenic amyloid

NATURE COMMUNICATIONS

IF15.7

2020-08-14

OAAI

Lu, Jiahui; Cao, Qin; Hughes, Michael P.; Sawaya, Michael R.; Boyer, David R.; Cascio, Duilio; Eisenberg, David S.

Crystal structure of a conformational antibody that binds tau oligomers and inhibits pathological seeding by extracts from donors with Alzheimer's disease 结合tau寡聚体并抑制阿尔茨海默氏病供体提取物的病理播种的构象抗体的晶体结构

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2020-07-01

OAAI

Abskharon, Romany; Seidler, Paul M.; Sawaya, Michael R.; Cascio, Duilio; Yang, Tianxiao P.; Philipp, Stephan; Williams, Christopher Kazu; Newell, Kathy L.; Ghetti, Bernardino; DeTure, Michael A.; Dickson, Dennis W.; Vinters, Harry V.; Felgner, Philip L.; Nakajima, Rie; Glabe, Charles G.; Eisenberg, David S.

Serial femtosecond crystallography on in vivo-grown crystals drives elucidation of mosquitocidal Cyt1Aa bioactivation cascade

NATURE COMMUNICATIONS

IF15.7

2020-03-02

OAAI

Tetreau, Guillaume; Banneville, Anne-Sophie; Andreeva, Elena A.; Brewster, Aaron S.; Hunter, Mark S.; Sierra, Raymond G.; Teulon, Jean-Marie; Young, Iris D.; Burke, Niamh; Grunewald, Tilman A.; Beaudouin, Joel; Snigireva, Irina; Fernandez-Luna, Maria Teresa; Burt, Alister; Park, Hyun-Woo; Signor, Luca; Bafna, Jayesh A.; Sadir, Rabia; Fenel, Daphna; Boeri-Erba, Elisabetta; Bacia, Maria; Zala, Ninon; Laporte, Frederic; Despres, Laurence; Weik, Martin; Boutet, Sebastien; Rosenthal, Martin; Coquelle, Nicolas; Burghammer, Manfred; Cascio, Duilio; Sawaya, Michael R.; Winterhalter, Mathias; Gratton, Enrico; Gutsche, Irina; Federici, Brian; Pellequer, Jean-Luc; Sauter, Nicholas K.; Colletier, Jacques-Philippe

Structure-based inhibitors halt prion-like seeding by Alzheimer's disease?and tauopathy?derived brain tissue samples

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2019-11-01

OAAI

Seidler, Paul Matthew; Boyer, David R.; Murray, Kevin A.; Yang, Tianxiao P.; Bentzel, Megan; Sawaya, Michael R.; Rosenberg, Gregory; Cascio, Duilio; Williams, Christopher Kazu; Newell, Kathy L.; Ghetti, Bernardino; DeTure, Michael A.; Dickson, Dennis W.; Vinters, Harry V.; Eisenberg, David S.

Structure-based inhibitors of amyloid beta core suggest a common interface with tau

ELIFE

IF0

2019-10-15

OAAI

Griner, Sarah L.; Seidler, Paul; Bowler, Jeannette; Murray, Kevin A.; Yang, Tianxiao Peter; Sahay, Shruti; Sawaya, Michael R.; Cascio, Duilio; Rodriguez, Jose A.; Philipp, Stephan; Sosna, Justyna; Glabe, Charles G.; Gonen, Tamir; Eisenberg, David S.

Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation (vol 25, pg 463, 2018)

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2019-09-17

OAAI

Guenther, Elizabeth L.; Cao, Qin; Trinh, Hamilton; Lu, Jiahui; Sawaya, Michael R.; Cascio, Duilio; Boyer, David R.; Rodriguez, Jose A.; Hughes, Michael P.; Eisenberg, David S.

Characterization of Reactive Organometallic Species via MicroED

ACS CENTRAL SCIENCE

IF10.4

2019-09-06

OAAI

Jones, Christopher G.; Asay, Matthew; Kim, Lee Joon; Kleinsasser, Jack F.; Saha, Ambarneil; Fulton, Tyler J.; Berkley, Kevin R.; Cascio, Duilio; Malyutin, Andrey G.; Conley, Matthew P.; Stoltz, Brian M.; Lavallo, Vincent; Rodriguez, Jose A.; Nelson, Hosea M.

研究方向