Michelle E. Ehrlich - Publications, H-index & Citations

Michelle E. Ehrlich

icahn school of medicine at mount sinai

59H指数

240论文数

1.2W被引数

收录论文 97

发表时间

miR155, triplicated in Down syndrome, regulates the development of neural stem cells and GABAergic interneurons in Alzheimer's disease mouse and human iPSC models miR155（在唐氏综合征中三倍表达）调控阿尔茨海默病小鼠模型和人诱导多能干细胞模型中神经干细胞和GABA能中间神经元的发展

Alzheimers & Dementia

IF11.1

2026-08-10

OAAI

Xiaodong Zhu; Jean-Vianney Haure-Mirande; Mesude Bicak; Pengfei Dong; Ilya Kruglikov; Aiqun Li; Aisha Al-subaie; Valentina Fossati; Scott Noggle; Sam Gandy; Michelle E. Ehrlich

Molecular Networks and Key Regulators Underlying Resilience of the Human Brain to Aging and Dementia 人类大脑对衰老和痴呆的韧性背后的分子网络及关键调控因子

Biomolecules

IF4.8

2026-07-28

OAAI

Lei Guo; Nicholas Grimaldi; Minghui Wang; Lap Ho; Ben Shackleton; Ryan Neff; Erming Wang; Zhidong Tu; Sam Gandy; Vahram Haroutunian; Michelle E. Ehrlich; Charles Mobbs; Bin Zhang

Endogenously generated Dutch-type Aβ non-fibrillar aggregates dysregulate presynaptic neurotransmission in the absence of detectable inflammation 内源性生成的荷兰型Aβ非纤维状聚集物在不产生可检测炎症的情况下破坏突触前神经传递

alzheimer's & dementia

IF0

2026-06-09

OAAI

Emilie L. Castranio; Merina Varghese; Elentina K. Argyrousi; Kuldeep Tripathi; Yong Huang; Akiko Asada; Linda Söderberg; Erin Bresnahan; David Lerner; Francesca Garretti; Hong Zhang; Jonathan van de Loo; Cheryl D. Stimpson; Ronan Talty; Charles Glabe; Efrat Levy; Minghui Wang; Marjan Ilkov; Toshiharu Suzuki; Kanae Ando; Bin Zhang; Lars Lannfelt; Brigitte Guérin; William D. Lubell; Shai Rahimipour; Dara L. Dickstein; Sam Gandy; Ottavio Arancio; Michelle E. Ehrlich

Microglia ablation is sufficient to prevent spontaneous withdrawal following perinatal morphine exposure 小胶质细胞清除足以预防围产期吗啡暴露后的自发戒断反应。

brain, behavior, and immunity

IF0

2026-04-03

PREAI

Julia R. Ferrante; Kyle Ploense; Khaled Althobaiti; Darlinda Shillingford; Molly S. Estill; Julie A. Blendy; Michelle E. Ehrlich

Cerulenin partially corrects the disrupted developmental transcriptomic signature in Huntington's disease striatal medium spiny neurons Cerulenin部分纠正了亨廷顿病纹状体中棘状神经元的发育转录组特征紊乱。

Stem Cells

IF3.6

2025-08-01

PREAI

Galicia Aguirre, Carlos; Tshilenge, Kizito-Tshitoko; Battistoni, Elena; Lopez-Ramirez, Alejandro; Naphade, Swati; Perez, Kevin; Gerencser, Akos A.; Song, Sicheng; Mooney, Sean D.; Melov, Simon; Ehrlich, Michelle E.; Ellerby, Lisa M.

Characterization of human cytomegalovirus infection dynamics in human microglia 人巨细胞病毒感染在人微胶质细胞中的动力学表征

JOURNAL OF GENERAL VIROLOGY

IF4.3

2025-04-29

PREAI

Guaita, Marcos Nuevalos; Jimoh, Tajudeen O.; Barrall, Emma B.; Atanasoff, Kristina E.; Ehrlich, Michelle E.; Gandy, Sam; Garcia-Rios, Estefani; Romero, Pilar Perez; Duty, J. Andrew; Tortorella, Domenico

Alzheimer's disease-associated CD83(+) microglia are linked with increased immunoglobulin G4 and human cytomegalovirus in the gut, vagal nerve, and brain

ALZHEIMERS & DEMENTIA

IF11.1

2024-12-19

OAAI

Readhead, Benjamin P.; Mastroeni, Diego F.; Wang, Qi; Sierra, Maria A.; de avila, Camila; Jimoh, Tajudeen O.; Haure-Mirande, Jean-Vianney; Atanasoff, Kristina E.; Nolz, Jennifer; Suazo, Crystal; Barton, Nathaniel J.; Orszulak, Adrian R.; Chigas, Samantha M.; Tran, Khanh; Mirza, Anne; Ryon, Krista; Proszynski, Jacqueline; Najjar, Deena; Dudley, Joel T.; Liu, Sean T. H.; Gandy, Sam; Ehrlich, Michelle E.; Alsop, Eric; Antone, Jerry; Reiman, Rebecca; Funk, Cory; Best, Rebecca L.; Jhatro, Michael; Kamath, Kathy; Shon, John; Kowalik, Timothy F.; Bennett, David A.; Liang, Winnie S.; Serrano, Geidy E.; Beach, Thomas G.; Van Keuren-Jensen, Kendall; Mason, Christopher E.; Chan, Yingleong; Lim, Elaine T.; Tortorella, Domenico; Reiman, Eric M.

Intranasal long R3 insulin-like growth factor-1 treatment promotes amyloid plaque remodeling in cerebral cortex but fails to preserve cognitive function in male 5XFAD mice

JOURNAL OF ALZHEIMERS DISEASE

IF3.1

2024-11-29

PREAI

Engel, Matthew G.; Narayan, Sushma; Cui, Min-Hui; Branch, Craig A.; Zhang, Xusheng; Gandy, Samuel E.; Ehrlich, Michelle; Huffman, Derek M.

Dual-specificity protein phosphatase 6 (DUSP6) overexpression reduces amyloid load and improves memory deficits in male 5xFAD mice

FRONTIERS IN AGING NEUROSCIENCE

IF4.5

2024-06-28

OAAI

Pan, Allen L.; Audrain, Mickael; Sakakibara, Emmy; Joshi, Rajeev; Zhu, Xiaodong; Wang, Qian; Wang, Minghui; Beckmann, Noam D.; Schadt, Eric E.; Gandy, Sam; Zhang, Bin; Ehrlich, Michelle E.; Salton, Stephen R.

TYROBP/DAP12 knockout in Huntington's disease Q175 mice cell-autonomously decreases microglial expression of disease-associated genes and non-cell-autonomously mitigates astrogliosis and motor deterioration

JOURNAL OF NEUROINFLAMMATION

IF10.1

2024-03-08

OAAI

Creus-Muncunill, Jordi; Haure-Mirande, Jean Vianney; Mattei, Daniele; Bons, Joanna; Ramirez, Angie V.; Hamilton, B. Wade; Corwin, Chuhyon; Chowdhury, Sarah; Schilling, Birgit; Ellerby, Lisa M.; Ehrlich, Michelle E.

Proteomic analysis of X-linked dystonia parkinsonism disease striatal neurons reveals altered RNA metabolism and splicing X连锁肌张力障碍帕金森病纹状体神经元的蛋白质组学分析揭示了RNA代谢和剪接的改变

NEUROBIOLOGY OF DISEASE

IF5.6

2024-01-01

OAAI

Tshilenge, Kizito-Tshitoko; Bons, Joanna; Aguirre, Carlos Galicia; Geronimo-Olvera, Cristian; Shah, Samah; Rose, Jacob; Gerencser, Akos A.; Mak, Sally K.; Ehrlich, Michelle E.; Bragg, Cristopher; Schilling, Birgit; Ellerby, Lisa M.

miR155, TREM2, INPP5D: Disease stage and cell-type are essential considerations when targeting clinical interventions based on mouse models of Alzheimer's amyloidopathy (vol 20, 214, 2023)

JOURNAL OF NEUROINFLAMMATION

IF10.1

2023-11-30

OAAI

Gandy, Sam; Ehrlich, Michelle E.

miR155, TREM2, INPP5D: Disease stage and cell type are essential considerations when targeting clinical interventions based on mouse models of Alzheimer's amyloidopathy

JOURNAL OF NEUROINFLAMMATION

IF10.1

2023-09-25

OAAI

Gandy, Sam; Ehrlich, Michelle E.

Moving the Needle on Alzheimer's Disease with an Anti-Oligomer Antibody

NEW ENGLAND JOURNAL OF MEDICINE

IF78.5

2023-01-05

PREAI

Gandy, Sam; Ehrlich, Michelle E.

Dual-Specificity Protein Phosphatase 4 (DUSP4) Overexpression Improves Learning Behavior Selectively in Female 5xFAD Mice, and Reduces β-Amyloid Load in Males and Females

CELLS

IF5.2

2022-12-01

OAAI

Microglial INPP5D limits plaque formation and glial reactivity in the PSAPP mouse model of Alzheimer's disease

ALZHEIMERS & DEMENTIA

IF11.1

2022-11-30

OAAI

Castranio, Emilie L.; Hasel, Philip; Haure-Mirande, Jean-Vianney; Ramirez Jimenez, Angie V.; Hamilton, B. Wade; Kim, Rachel D.; Glabe, Charles G.; Wang, Minghui; Zhang, Bin; Gandy, Sam; Liddelow, Shane A.; Ehrlich, Michelle E.

Intranasal Peptide Therapeutics: A Promising Avenue for Overcoming the Challenges of Traditional CNS Drug Development

CELLS

IF5.2

2022-11-16

OAAI

Bose, Meenakshi; Quipildor, Gabriela Farias; Ehrlich, Michelle E.; Salton, Stephen R.

Postnatal Conditional Deletion of Bcl11b in Striatal Projection Neurons Mimics the Transcriptional Signature of Huntington's Disease

BIOMEDICINES

IF3.9

2022-09-23

OAAI

Song, Sicheng; Muncunill, Jordi Creus; Aguirre, Carlos Galicia; Tshilenge, Kizito-Tshitoko; Hamilton, B. Wade; Gerencser, Akos A.; Benlhabib, Houda; Cirnaru, Maria-Daniela; Leid, Mark; Mooney, Sean D.; Ellerby, Lisa M.; Ehrlich, Michelle E.

Microglial TYROBP/DAP12 in Alzheimer's disease: Transduction of physiological and pathological signals across TREM2 阿尔茨海默病中的小胶质细胞TYROBP/DAP12: 跨TREM2的生理和病理信号的转导

MOLECULAR NEURODEGENERATION

IF17.5

2022-08-24

OAAI

Haure-Mirande, Jean-Vianney; Audrain, Mickael; Ehrlich, Michelle E.; Gandy, Sam

Neonatal Opioid Withdrawal Syndrome in Mice: Acute Molecular and Long-Term Behavioral Consequences

FASEB JOURNAL

IF4.2

2022-05-13

PREAI

Ferrante, Julia R.; Dunn, Amelia D.; Mengaziol, Juliet; Noreck, Julia; Lemchi, Crystal O.; Creus-Muncunill, Jordi; Ehrlich, Michelle E.; Blendy, Julie A.

研究方向