未登录 分享 收藏
Prions and protein aggregates as pathogens, self-propagating structures, biomarkers, and therapeutic targets 朊病毒和蛋白质聚集物作为病原体、自传播结构、生物标志物和治疗靶点 Caughey, Byron; Artikis, Efrosini; Shoup, Daniel; Orru, Christina D.; Alam, Parvez; Parveen, Sabiha; King, Samantha; Soukup, Jakub; Hughson, Andrew G.; Priola, Suzette A. 分享 收藏
分享 收藏
分享 收藏
分享 收藏
Alpha-synuclein seed amplification assays: Data sharing, standardization needed for clinical use Alpha-synuclein种子扩增试验：数据共享和标准化对临床应用至关重要 Lashuel, Hilal A.; Surmeier, D. James; Simuni, Tanya; Merchant, Kalpana; Caughey, Byron; Soto, Claudio; Fares, Mohamed-Bilal; Heym, Roland G.; Melki, Ronald 分享 收藏
Cryo-EM structure of a natural prion: chronic wasting disease fibrils from deer Alam, Parvez; Hoyt, Forrest; Artikis, Efrosini; Soukup, Jakub; Hughson, Andrew G.; Schwartz, Cindi L.; Barbian, Kent; Miller, Michael W.; Race, Brent; Caughey, Byron 分享 收藏
Enhanced quantitation of pathological α-synuclein in patient biospecimens by RT-QuIC seed amplification assays Srivastava, Ankit; Wang, Qinlu; Orru, Christina D.; Fernandez, Manel; Compta, Yaroslau; Ghetti, Bernardino; Zanusso, Gianluigi; Zou, Wen-Quan; Caughey, Byron; Beauchemin, Catherine A. A. 分享 收藏
Seeding activity of human superoxide dismutase 1 aggregates in familial and sporadic amyotrophic lateral sclerosis postmortem neural tissues by real-time quaking-induced conversion Mielke, Justin K.; Klingeborn, Mikael; Schultz, Eric P.; Markham, Erin L.; Reese, Emily D.; Alam, Parvez; Mackenzie, Ian R.; Ly, Cindy V.; Caughey, Byron; Cashman, Neil R.; Leavens, Moses J. 分享 收藏
Sensitive detection of pathological seeds of α-synuclein, tau and prion protein on solid surfaces Orru, Christina D.; Groveman, Bradley R.; Hughson, Andrew G.; Barrio, Tomas; Isiofia, Kachi; Race, Brent; Ferreira, Natalia C.; Gambetti, Pierluigi; Schneider, David A.; Masujin, Kentaro; Miyazawa, Kohtaro; Ghetti, Bernardino; Zanusso, Gianluigi; Caughey, Byron 分享 收藏
Discovery of potent inhibitors of α-synuclein aggregation using structure-based iterative learning Horne, Robert I.; Andrzejewska, Ewa A.; Alam, Parvez; Brotzakis, Z. Faidon; Srivastava, Ankit; Aubert, Alice; Nowinska, Magdalena; Gregory, Rebecca C.; Staats, Roxine; Possenti, Andrea; Chia, Sean; Sormanni, Pietro; Ghetti, Bernardino; Caughey, Byron; Knowles, Tuomas P. J.; Vendruscolo, Michele 分享 收藏
Chronic Wasting Disease: State of the Science Bartz, Jason C.; Benavente, Rebeca; Caughey, Byron; Christensen, Sonja; Herbst, Allen; Hoover, Edward A.; Mathiason, Candace K.; McKenzie, Debbie; Morales, Rodrigo; Schwabenlander, Marc D.; Walsh, Daniel P. 分享 收藏
Large-scale validation of skin prion seeding activity as a biomarker for diagnosis of prion diseases Zhang, Weiguanliu; Orru, Christina D.; Foutz, Aaron; Ding, Mingxuan; Yuan, Jue; Shah, Syed Zahid Ali; Zhang, Jing; Kotobelli, Keisi; Gerasimenko, Maria; Gilliland, Tricia; Chen, Wei; Tang, Michelle; Cohen, Mark; Safar, Jiri; Xu, Bin; Hong, Dao-Jun; Cui, Li; Hughson, Andrew G.; Schonberger, Lawrence B.; Tatsuoka, Curtis; Chen, Shu G.; Greenlee, Justin J.; Wang, Zerui; Appleby, Brian S.; Caughey, Byron; Zou, Wen-Quan 分享 收藏
Tau seeding without tauopathy Lacroix, Michael S.; Artikis, Efrosini; Hitt, Brian D.; Beaver, Joshua D.; Estill-Terpack, Sandi-Jo; Gleason, Kelly; Tamminga, Carol A.; Evers, Bret M.; White III, Charles L.; Caughey, Byron; Diamond, Marc I. 分享 收藏
Neuronal Ndst1 depletion accelerates prion protein clearance and slows neurodegeneration in prion infection Aguilar-Calvo, Patricia; Malik, Adela; Sandoval, Daniel R.; Barback, Christopher; Orru, Christina D.; Standke, Heidi G.; Thomas, Olivia R.; Dwyer, Chrissa A.; Pizzo, Donald P.; Bapat, Jaidev; Soldau, Katrin; Ogawa, Ryotaro; Riley, Mckenzie B.; Nilsson, K. Peter R.; Kraus, Allison; Caughey, Byron; Iliff, Jeffrey J.; Vera, David R.; Esko, Jeffrey D.; Sigurdson, Christina J. 分享 收藏
α-Synuclein seeding activity in duodenum biopsies from Parkinson's disease patients Vascellari, Sarah; Orru, Christina; Groveman, Bradley; Parveen, Sabiha; Fenu, Giuseppe; Pisano, Giada; Piga, Giuseppe G.; Serra, Giulia L.; Oppo, Valentina; Murgia, Daniela; Perra, Andrea; Angius, Fabrizio A.; Hughson, Andrew L.; Haigh, Cathryn A.; Manzin, Aldo L.; Cossu, Giovanni A.; Caughey, Byron L. 分享 收藏
Case report of a patient with unclassified tauopathy with molecular and neuropathological features of both progressive supranuclear palsy and corticobasal degeneration Koga, Shunsuke; Metrick II, Michael A.; Golbe, Lawrence I.; Santambrogio, Alessia; Kim, Minji; Soto-Beasley, Alexandra I.; Walton, Ronald L.; Baker, Matthew C.; De Castro, Cristhoper Fernandez; DeTure, Michael; Russell, David; Navia, Bradford A.; Sandiego, Christine; Ross, Owen A.; Vendruscolo, Michele; Caughey, Byron; Dickson, Dennis W. 分享 收藏
A novel subtype of sporadic Creutzfeldt-Jakob disease with PRNP codon 129MM genotype and PrP plaques (May, 10.1007/s00401-023-02581-1, 2023) Bayazid, Rabeah; Orru, Christina; Aslam, Rabail; Cohen, Yvonne; Silva-Rohwer, Amelia; Lee, Seong-Ki; Occhipinti, Rossana; Kong, Qingzhong; Shetty, Shashirekha; Cohen, Mark L.; Caughey, Byron; Schonberger, Lawrence B.; Appleby, Brian S.; Cali, Ignazio 分享 收藏
A novel subtype of sporadic Creutzfeldt-Jakob disease with PRNP codon 129MM genotype and PrP plaques Bayazid, Rabeah; Orru', Christina; Aslam, Rabail; Cohen, Yvonne; Silva-Rohwer, Amelia; Lee, Seong-Ki; Occhipinti, Rossana; Kong, Qingzhong; Shetty, Shashirekha; Cohen, Mark L.; Caughey, Byron; Schonberger, Lawrence B.; Appleby, Brian S.; Cali, Ignazio 分享 收藏
Seed amplification and neurodegeneration marker trajectories in individuals at risk of prion disease 有朊病毒疾病风险的个体的种子扩增和神经变性标记轨迹 Mok, Tze How; Nihat, Akin; Majbour, Nour; Sequeira, Danielle; Holm-Mercer, Leah; Coysh, Thomas; Darwent, Lee; Batchelor, Mark; Groveman, Bradley R.; Orr, Christina D.; Hughson, Andrew G.; Heslegrave, Amanda; Laban, Rhiannon; Veleva, Elena; Paterson, Ross W.; Keshavan, Ashvini; Schott, Jonathan M.; Swift, Imogen J.; Heller, Carolin; Rohrer, Jonathan D.; Gerhard, Alexander; Butler, Christopher; Rowe, James B.; Masellis, Mario; Chapman, Miles; Lunn, Michael P.; Bieschke, Jan; Jackson, Graham S.; Zetterberg, Henrik; Caughey, Byron; Rudge, Peter; Collinge, John; Mead, Simon 分享 收藏
.png){kind=icon}
未登录.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
