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Data-driven identification of plasma metabolite clusters and metabolites of interest for potential detection of early-stage non-small cell lung cancer cases versus cancer-free controls Kim, Julian O.; Balshaw, Robert; Trevena, Connel; Banerji, Shantanu; Murphy, Leigh; Dawe, David; Tan, Lawrence; Srinathan, Sadeesh; Buduhan, Gordon; Kidane, Biniam; Qing, Gefei; Domaratzki, Michael; Aliani, Michel 分享 收藏
Nuclear TIGAR mediates an epigenetic and metabolic autoregulatory loop via NRF2 in cancer therapeutic resistance 核TIGAR通过NRF2介导表观遗传和代谢自调节环在癌症治疗抗性中 Wang, Hong; Wang, Qianqian; Cai, Guodi; Duan, Zhijian; Nugent, Zoann; Huang, Jie; Zheng, Jianwei; Borowsky, Alexander D.; Li, Jian Jian; Liu, Peiqing; Kung, Hsing-Jien; Murphy, Leigh; Chen, Hong-Wu; Wang, Junjian 分享 收藏
The association between genomic alterations and body mass index in patients with early breast cancer 早期乳腺癌患者基因组改变与体重指数的关系 Nguyen, Ha-Linh; Geukens, Tatjana; Maetens, Marion; Van Baelen, Karen; De Schepper, Maxim; Leduc, Sophia; Isnaldi, Edoardo; Aparicio, Sam; Borg, Ake; Brock, Jane; Broeks, Annegien; Caldas, Carlos; Green, Andrew; Khout, Hazem; Jorunn, Eyfjoro; Knappskog, Stian; Krishnamurthy, Savitri; Lakhani, Sunil; Langerod, Anita; Martens, John W. M.; Murphy, Leigh; Nik-Zainal, Serena; Purdie, Colin; Rakha, Emad; Richardson, Andrea; Salomon, Anne; Simpson, Peter; Sotiriou, Christos; Span, Paul; Tan, Benita Kiat-Tee; Thompson, Alastair; Tommasi, Stefania; De Vijver, Marc Van; Van Laere, Steven; Viari, Alain; Floris, Giuseppe; Biganzoli, Elia; Richard, Francois; Desmedt, Christine 分享 收藏
DNA methylation landscapes of 1538 breast cancers reveal a replication-linked clock, epigenomic instability and cis-regulation 1538乳腺癌的DNA甲基化景观揭示了与复制相关的时钟，表观基因组不稳定性和顺式调节 Batra, Rajbir Nath; Lifshitz, Aviezer; Vidakovic, Ana Tufegdzic; Chin, Suet-Feung; Sati-Batra, Ankita; Sammut, Stephen-John; Provenzano, Elena; Ali, H. Raza; Dariush, Ali; Bruna, Alejandra; Murphy, Leigh; Purushotham, Arnie; Ellis, Ian; Green, Andrew; Garrett-Bakelman, Francine E.; Mason, Chris; Melnick, Ari; Aparicio, Samuel A. J. R.; Rueda, Oscar M.; Tanay, Amos; Caldas, Carlos 分享 收藏
Dynamics of breast cancer relapse reveal molecularly defined late recurring ER-positive subgroups: Results from the METABRIC study Curtis, C.; Rueda, O. M.; Sammut, S-J; Chin, S-F; Caswell-Jin, J. L.; Seoane, J. A.; Callari, M.; Batra, R.; Pereira, B.; Bruna, A.; Ali, H. R.; Provenzano, E.; Liu, B.; Parisien, M.; Gillett, C.; McKinney, S.; Green, A.; Murphy, L.; Purushotham, A.; Ellis, I.; Pharoah, P.; Rueda, C.; Aparicio, S.; Caldas, C. 分享 收藏
Unlocking the transcriptomic potential of formalin-fixed paraffin embedded breast cancer tissues for high-throughput genomic analysis Turnbull, A. K.; Selli, C.; Martinez-Perez, C.; Fernando, A.; Renshaw, L.; Keys, J.; Figueroa, J. D.; He, X.; Tanioka, M.; Munro, A.; Murphy, L.; Fawkes, A.; Clark, R.; Coutts, A.; Perou, C. M.; Carey, L. A.; Dixon, J. M.; Sims, A. H. 分享 收藏
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Estrogen receptor subtypes dictate the proliferative nature of the mammary gland Dall, Genevieve V.; Hawthorne, Samuel; Seyed-Razavi, Yashar; Vieusseux, Jessica; Wu, Wanfu; Gustafsson, Jan-Ake; Byrne, David; Murphy, Leigh; Risbridger, Gail P.; Britt, Kara L. 分享 收藏
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Breast Cancers Activate Stromal Fibroblast-Induced Suppression of Progenitors in Adjacent Normal Tissue Chatterjee, Sumanta; Basak, Pratima; Buchel, Edward; Safneck, Janice; Murphy, Leigh C.; Mowat, Michael; Kung, Sam K.; Eirew, Peter; Eaves, Connie J.; Raouf, Afshin 分享 收藏
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Reprogramming metabolism by histone methyltransferase NSD2 drives endocrine resistance via coordinated activation of pentose phosphate pathway enzymes Wang, Junjian; Duan, Zhijian; Nugent, Zoann; Zou, June X.; Borowsky, Alexander D.; Zhang, Yanhong; Tepper, Clifford G.; Li, Jian Jian; Fiehn, Oliver; Xu, Jianzhen; Kung, Hsing-Jien; Murphy, Leigh C.; Chen, Hong-Wu 分享 收藏
The somatic mutation profiles of 2,433 breast cancers refine their genomic and transcriptomic landscapes (vol 7, 11479, 2016) Pereira, Bernard; Chin, Suet-Feung; Rueda, Oscar M.; Vollan, Hans-Kristian Moen; Provenzano, Elena; Bardwell, Helen A.; Pugh, Michelle; Jones, Linda; Russell, Roslin; Sammut, Stephen-John; Tsui, Dana W. Y.; Liu, Bin; Dawson, Sarah-Jane; Abraham, Jean; Northen, Helen; Peden, John F.; Mukherjee, Abhik; Turashvili, Gulisa; Green, Andrew R.; McKinney, Steve; Oloumi, Arusha; Shah, Sohrab; Rosenfeld, Nitzan; Murphy, Leigh; Bentley, David R.; Ellis, Ian O.; Purushotham, Arnie; Pinder, Sarah E.; Borresen-Dale, Anne-Lise; Earl, Helena M.; Pharoah, Paul D.; Ross, Mark T.; Aparicio, Samuel; Caldas, Carlos 分享 收藏
The somatic mutation profiles of 2,433 breast cancers refines their genomic and transcriptomic landscapes 2,433乳腺癌的体细胞突变谱改善了它们的基因组和转录组景观 Pereira, Bernard; Chin, Suet-Feung; Rueda, Oscar M.; Vollan, Hans-Kristian Moen; Provenzano, Elena; Bardwell, Helen A.; Pugh, Michelle; Jones, Linda; Russell, Roslin; Sammut, Stephen-John; Tsui, Dana W. Y.; Liu, Bin; Dawson, Sarah-Jane; Abraham, Jean; Northen, Helen; Peden, John F.; Mukherjee, Abhik; Turashvili, Gulisa; Green, Andrew R.; McKinney, Steve; Oloumi, Arusha; Shah, Sohrab; Rosenfeld, Nitzan; Murphy, Leigh; Bentley, David R.; Ellis, Ian O.; Purushotham, Arnie; Pinder, Sarah E.; Borresen-Dale, Anne-Lise; Earl, Helena M.; Pharoah, Paul D.; Ross, Mark T.; Aparicio, Samuel; Caldas, Carlos 分享 收藏
The steroid receptor RNA activator protein (SRAP) controls cancer cell migration/motility Yan, Yi; Cooper, Charlton; Hamedani, Mohammad K.; Guppy, Brent; Xu, Wayne; Tsuyuki, Deborah; Zhang, Christine; Nugent, Zoann; Blanchard, Anne; Davie, James R.; McManus, Kirk; Murphy, Leigh C.; Myal, Yvonne; Leygue, Etienne 分享 收藏
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