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Human iPSC-derived pericyte-like cells carrying APP Swedish mutation overproduce beta-amyloid and induce cerebral amyloid angiopathy-like changes 携带APP瑞典突变的人iPSC衍生的周细胞样细胞过度产生 β-淀粉样蛋白并诱导脑淀粉样血管病样变化 Wu, Ying-Chieh; Lehtonen, Sarka; Trontti, Kalevi; Kauppinen, Riitta; Kettunen, Pinja; Leinonen, Ville; Laakso, Markku; Kuusisto, Johanna; Hiltunen, Mikko; Hovatta, Iiris; Freude, Kristine; Dhungana, Hiramani; Koistinaho, Jari; Rolova, Taisia 分享 收藏
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Cell-Type Composition Affects Adipose Gene Expression Associations With Cardiometabolic Traits Brotman, Sarah M.; Oravilahti, Anniina; Rosen, Jonathan D.; Alvarez, Marcus; Heinonen, Sini; van der Kolk, Birgitta W.; Silva, Lilian Fernandes; Perrin, Hannah J.; Vadlamudi, Swarooparani; Pylant, Cortney; Deochand, Sonia; Basta, Patricia V.; Valone, Jordan M.; Narain, Morgan N.; Stringham, Heather M.; Boehnke, Michael; Kuusisto, Johanna; Love, Michael I.; Pietilainen, Kirsi H.; Pajukanta, Paivi; Laakso, Markku; Mohlke, Karen L. 分享 收藏
SARS-CoV-2 Infection of Human Neurons Is TMPRSS2 Independent, Requires Endosomal Cell Entry, and Can Be Blocked by Inhibitors of Host Phosphoinositol-5 Kinase Kettunen, Pinja; Lesnikova, Angelina; Rasanen, Noora; Ojha, Ravi; Palmunen, Leena; Laakso, Markku; Lehtonen, Sarka; Kuusisto, Johanna; Pietilainen, Olli; Saber, Saber H.; Joensuu, Merja; Vapalahti, Olli P.; Koistinaho, Jari; Rolova, Taisia; Balistreri, Giuseppe 分享 收藏
Integrating transcriptomics, metabolomics, and GWAS helps reveal molecular mechanisms for metabolite levels and disease risk 整合转录组学、代谢组学和gw有助于揭示代谢物水平和疾病风险的分子机制 Yin, Xianyong; Bose, Debraj; Kwon, Annie; Hanks, Sarah C.; Jackson, Anne U.; Stringham, Heather M.; Welch, Ryan; Oravilahti, Anniina; Silva, Lilian Fernandes; Locke, FinnGen Adam E.; Fuchsberger, Christian; Service, Susan K.; Erdos, Michael R.; Bonnycastle, Lori L.; Kuusisto, Johanna; Stitziel, Nathan O.; Hall, Ira M.; Morrison, Jean; Ripatti, Samuli; Palotie, Aarno; Freimer, Nelson B.; Collins, Francis S.; Mohlke, Karen L.; Scott, Laura J.; Fauman, Eric B.; Burant, Charles; Boehnke, Michael; Laakso, Markku; Wen, Xiaoquan 分享 收藏
Genetic loci and prioritization of genes for kidney function decline derived from a meta-analysis of 62 longitudinal genome-wide association studies 基于62项纵向全基因组关联研究的荟萃分析得出的肾功能下降相关遗传位点及基因优先排序 Gorski, Mathias; Rasheed, Humaira; Teumer, Alexander; Thomas, Laurent F.; Graham, Sarah E.; Sveinbjornsson, Gardar; Winkler, Thomas W.; Guenther, Felix; Stark, Klaus J.; Chai, Jin-Fang; Tayo, Bamidele O.; Wuttke, Matthias; Li, Yong; Tin, Adrienne; Ahluwalia, Tarunveer S.; Arnlov, Johan; Asvold, Bjorn Olav; Bakker, Stephan J. L.; Banas, Bernhard; Bansal, Nisha; Biggs, Mary L.; Biino, Ginevra; Bohnke, Michael; Boerwinkle, Eric; Bottinger, Erwin P.; Brenner, Hermann; Brumpton, Ben; Carroll, Robert J.; Chaker, Layal; Chalmers, John; Chee, Miao-Li; Chee, Miao-Ling; Cheng, Ching-Yu; Chu, Audrey Y.; Ciullo, Marina; Cocca, Massimiliano; Cook, James P.; Coresh, Josef; Cusi, Daniele; de Borst, Martin H.; Degenhardt, Frauke; Eckardt, Kai-Uwe; Endlich, Karlhans; Evans, Michele K.; Feitosa, Mary F.; Franke, Andre; Freitag-Wolf, Sandra; Fuchsberger, Christian; Gampawar, Piyush; Gansevoort, Ron T.; Ghanbari, Mohsen; Ghasemi, Sahar; Giedraitis, Vilmantas; Gieger, Christian; Gudbjartsson, Daniel F.; Hallan, Stein; Hamet, Pavel; Hishida, Asahi; Ho, Kevin; Hofer, Edith; Holleczek, Bernd; Holm, Hilma; Hoppmann, Anselm; Horn, Katrin; Hutri-Kahonen, Nina; Hveem, Kristian; Hwang, Shih-Jen; Ikram, M. Arfan; Josyula, Navya Shilpa; Jung, Bettina; Kahonen, Mika; Karabegovic, Irma; Khor, Chiea-Chuen; Koenig, Wolfgang; Kramer, Holly; Kramer, Bernhard K.; Kuehnel, Brigitte; Kuusisto, Johanna; Laakso, Markku; Lange, Leslie A.; Lehtimaki, Terho; Li, Man; Lieb, Wolfgang; Lind, Lars; Lindgren, Cecilia M.; Loos, Ruth J. F.; Lukas, Mary Ann; Lyytikainen, Leo-Pekka; Mahajan, Anubha; Matias-Garcia, Pamela R.; Meisinger, Christa; Meitinger, Thomas; Melander, Olle; Milaneschi, Yuri; Mishra, Pashupati P.; Mononen, Nina; Morris, Andrew P.; Mychaleckyj, Josyf C.; Nadkarni, Girish N.; Naito, Mariko; Nakatochi, Masahiro; Nalls, Mike A.; Nauck, Matthias; Nikus, Kjell; Ning, Boting; Nolte, Ilja M.; Nutile, Teresa; O'Donoghue, Michelle L.; O'Connell, Jeffrey; Olafsson, Isleifur; Orho-Melander, Marju; Parsa, Afshin; Pendergrass, Sarah A.; Penninx, Brenda W. J. H.; Pirastu, Mario; Preuss, Michael H.; Psaty, Bruce M.; Raffield, Laura M.; Raitakari, Olli T.; Rheinberger, Myriam; Rice, Kenneth M.; Rizzi, Federica; Rosenkranz, Alexander R.; Rossing, Peter; Rotter, Jerome I.; Ruggiero, Daniela; Ryan, Kathleen A.; Sabanayagam, Charumathi; Salvi, Erika; Schmidt, Helena; Schmidt, Reinhold; Scholz, Markus; Schoettker, Ben; Schulz, Christina-Alexandra; Sedaghat, Sanaz; Shaffer, Christian M.; Sieber, Karsten B.; Sim, Xueling; Sims, Mario; Snieder, Harold; Stanzick, Kira J.; Thorsteinsdottir, Unnur; Stocker, Hannah; Strauch, Konstantin; Stringham, Heather M.; Sulem, Patrick; Szymczak, Silke; Taylor, Kent D.; Thio, Chris H. L.; Tremblay, Johanne; Vaccargiu, Simona; van der Harst, Pim; van der Most, Peter J.; Verweij, Niek; Volker, Uwe; Wakai, Kenji; Waldenberger, Melanie; Wallentin, Lars; Wallner, Stefan; Wang, Judy; Waterworth, Dawn M.; White, Harvey D.; Willer, Cristen J.; Wong, Tien-Yin; Woodward, Mark; Yang, Qiong; Yerges-Armstrong, Laura M.; Zimmermann, Martina; Zonderman, Alan B.; Bergler, Tobias; Stefansson, Kari; Boger, Carsten A.; Pattaro, Cristian; Koettgen, Anna; Kronenberg, Florian; Heid, Iris M. 分享 收藏
Differential and shared genetic effects on kidney function between diabetic and non-diabetic individuals 糖尿病和非糖尿病个体对肾功能的差异和共享遗传影响 Winkler, Thomas W.; Rasheed, Humaira; Teumer, Alexander; Gorski, Mathias; Rowan, Bryce X.; Stanzick, Kira J.; Thomas, Laurent F.; Tin, Adrienne; Hoppmann, Anselm; Chu, Audrey Y.; Tayo, Bamidele; Thio, Chris H. L.; Cusi, Daniele; Chai, Jin-Fang; Sieber, Karsten B.; Horn, Katrin; Li, Man; Scholz, Markus; Cocca, Massimiliano; Wuttke, Matthias; van der Most, Peter J.; Yang, Qiong; Ghasemi, Sahar; Nutile, Teresa; Li, Yong; Pontali, Giulia; Guenther, Felix; Dehghan, Abbas; Correa, Adolfo; Parsa, Afshin; Feresin, Agnese; de Vries, Aiko P. J.; Zonderman, Alan B.; Smith, Albert, V; Oldehinkel, Albertine J.; De Grandi, Alessandro; Rosenkranz, Alexander R.; Franke, Andre; Teren, Andrej; Metspalu, Andres; Hicks, Andrew A.; Morris, Andrew P.; Toenjes, Anke; Morgan, Anna; Podgornaia, Anna, I; Peters, Annette; Koerner, Antje; Mahajan, Anubha; Campbell, Archie; Freedman, Barry, I; Spedicati, Beatrice; Ponte, Belen; Schoettker, Ben; Brumpton, Ben; Banas, Bernhard; Kraemer, Bernhard K.; Jung, Bettina; Asvold, Bjorn Olav; Smith, Blair H.; Ning, Boting; Penninx, Brenda W. J. H.; Vanderwerff, Brett R.; Psaty, Bruce M.; Kammerer, Candace M.; Langefeld, Carl D.; Hayward, Caroline; Spracklen, Cassandra N.; Robinson-Cohen, Cassianne; Hartman, Catharina A.; Lindgren, Cecilia M.; Wang, Chaolong; Sabanayagam, Charumathi; Heng, Chew-Kiat; Lanzani, Chiara; Khor, Chiea-Chuen; Cheng, Ching-Yu; Fuchsberger, Christian; Gieger, Christian; Shaffer, Christian M.; Schulz, Christina-Alexandra; Willer, Cristen J.; Chasman, Daniel, I; Gudbjartsson, Daniel F.; Ruggiero, Daniela; Toniolo, Daniela; Czamara, Darina; Porteous, David J.; Waterworth, Dawn M.; Mascalzoni, Deborah; Mook-Kanamori, Dennis O.; Reilly, Dermot F.; Daw, E. Warwick; Hofer, Edith; Boerwinkle, Eric; Salvi, Erika; Bottinger, Erwin P.; Tai, E-Shyong; Catamo, Eulalia; Rizzi, Federica; Guo, Feng; Rivadeneira, Fernando; Guilianini, Franco; Sveinbjornsson, Gardar; Ehret, Georg; Waeber, Gerard; Biino, Ginevra; Girotto, Giorgia; Pistis, Giorgio; Nadkarni, Girish N.; Delgado, Graciela E.; Montgomery, Grant W.; Snieder, Harold; Campbell, Harry; White, Harvey D.; Gao, He; Stringham, Heather M.; Schmidt, Helena; Li, Hengtong; Brenner, Hermann; Holm, Hilma; Kirsten, Holgen; Kramer, Holly; Rudan, Igor; Nolte, Ilja M.; Tzoulaki, Ioanna; Olafsson, Isleifur; Martins, Jade; Cook, James P.; Wilson, James F.; Halbritter, Jan; Felix, Janine F.; Divers, Jasmin; Kooner, Jaspal S.; Lee, Jeannette Jen-Mai; O'Connell, Jeffrey; Rotter, Jerome, I; Liu, Jianjun; Xu, Jie; Thiery, Joachim; Arnlov, Johan; Kuusisto, Johanna; Jakobsdottir, Johanna; Tremblay, Johanne; Chambers, John C.; Whitfield, John B.; Gaziano, John M.; Marten, Jonathan; Coresh, Josef; Jonas, Jost B.; Mychaleckyj, Josyf C.; Christensen, Kaare; Eckardt, Kai-Uwe; Mohlke, Karen L.; Endlich, Karlhans; Dittrich, Katalin; Ryan, Kathleen A.; Rice, Kenneth M.; Taylor, Kent D.; Ho, Kevin; Nikus, Kjell; Matsuda, Koichi; Strauch, Konstantin; Miliku, Kozeta; Hveem, Kristian; Lind, Lars; Wallentin, Lars; Yerges-Armstrong, Laura M.; Raffield, Laura M.; Phillips, Lawrence S.; Launer, Lenore J.; Lyytikainen, Leo-Pekka; Lange, Leslie A.; Citterio, Lorena; Klaric, Lucija; Ikram, M. Arfan; Ising, Marcus; Kleber, Marcus E.; Francescatto, Margherita; Concas, Maria Pina; Ciullo, Marina; Piratsu, Mario; Orho-Melander, Marju; Laakso, Markku; Loeffler, Markus; Perola, Markus; de Borst, Martin H.; Gogele, Martin; La Bianca, Martina; Lukas, Mary Ann; Feitosa, Mary F.; Biggs, Mary L.; Wojczynski, Mary K.; Kavousi, Maryam; Kanai, Masahiro; Akiyama, Masato; Yasuda, Masayuki; Nauck, Matthias; Waldenberger, Melanie; Chee, Miao-Li; Chee, Miao-Ling; Boehnke, Michael; Preuss, Michael H.; Stumvoll, Michael; Province, Michael A.; Evans, Michele K.; O'Donoghue, Michelle L.; Kubo, Michiaki; Kahonen, Mika; Kastarinen, Mika; Nalls, Mike A.; Kuokkanen, Mikko; Ghanbari, Mohsen; Bochud, Murielle; Josyula, Navya Shilpa; Martin, Nicholas G.; Tan, Nicholas Y. Q.; Palmer, Nicholette D.; Pirastu, Nicola; Schupf, Nicole; Verweij, Niek; Hutri-Kahonen, Nina; Mononen, Nina; Bansal, Nisha; Devuyst, Olivier; Melander, Olle; Raitakari, Olli T.; Polasek, Ozren; Manunta, Paolo; Gasparini, Paolo; Mishra, Pashupati P.; Sulem, Patrick; Magnusson, Patrik K. E.; Elliott, Paul; Ridker, Paul M.; Hamet, Pavel; Svensson, Per O.; Joshi, Peter K.; Kovacs, Peter; Pramstaller, Peter P.; Rossing, Peter; Vollenweider, Peter; van der Harst, Pim; Dorajoo, Rajkumar; Sim, Ralene Z. H.; Burkhardt, Ralph; Tao, Ran; Noordam, Raymond; Magi, Reedik; Schmidt, Reinhold; de Mutsert, Renee; Rueedi, Rico; van Dam, Rob M.; Carroll, Robert J.; Gansevoort, Ron T.; Loos, Ruth J. F.; Felicita, Sala Cinzia; Sedaghat, Sanaz; Padmanabhan, Sandosh; Freitag-Wolf, Sandra; Pendergrass, Sarah A.; Graham, Sarah E.; Gordon, Scott D.; Hwang, Shih-Jen; Kerr, Shona M.; Vaccargiu, Simona; Patil, Snehal B.; Hallan, Stein; Bakker, Stephan J. L.; Lim, Su-Chi; Lucae, Susanne; Vogelezang, Suzanne; Bergmann, Sven; Corre, Tanguy; Ahluwalia, Tarunveer S.; Lehtimaki, Terho; Boutin, Thibaud S.; Meitinger, Thomas; Wong, Tien-Yin; Bergler, Tobias; Rabelink, Ton J.; Esko, Tonu; Haller, Toomas; Thorsteinsdottir, Unnur; Voelker, Uwe; Foo, Valencia Hui Xian; Salomaa, Veikko; Vitart, Veronique; Giedraitis, Vilmantas; Gudnason, Vilmundur; Jaddoe, Vincent W. V.; Huang, Wei; Zhang, Weihua; Wei, Wen Bin; Kiess, Wieland; Marz, Winfried; Koenig, Wolfgang; Lieb, Wolfgang; Gao, Xin; Sim, Xueling; Wang, Ya Xing; Friedlander, Yechiel; Tham, Yih-Chung; Kamatani, Yoichiro; Okada, Yukinori; Milaneschi, Yuri; Yu, Zhi; Stark, Klaus J.; Stefansson, Kari; Boeger, Carsten A.; Hung, Adriana M.; Kronenberg, Florian; Koettgen, Anna; Pattaro, Cristian; Heid, Iris M. 分享 收藏
Prevalence, characteristics, and mortality of patients with transthyretin amyloid cardiomyopathy in the Nordic countries Lauppe, Rosa; Hansen, Johan Liseth; Fornwall, Anna; Johansson, Katarina; Rozenbaum, Mark H.; Strand, Anne Mette; Vakevainen, Merja; Kuusisto, Johanna; Gude, Einar; Smith, J. Gustav; Gustafsson, Finn 分享 收藏
Healthcare resource use of patients with transthyretin amyloid cardiomyopathy 甲状腺素运载蛋白淀粉样心肌病患者的医疗资源使用 Lauppe, Rosa; Hansen, Johan Liseth; Fornwall, Anna; Johansson, Katarina; Rozenbaum, Mark H.; Strand, Anne Mette; Vakevainen, Merja; Kuusisto, Johanna; Gude, Einar; Smith, J. Gustav; Gustafsson, Finn 分享 收藏
Genome-wide association studies of metabolites in Finnish men identify disease-relevant loci 芬兰男性代谢物的全基因组关联研究确定了与疾病相关的基因座 Yin, Xianyong; Chan, Lap Sum; Bose, Debraj; Jackson, Anne U.; VandeHaar, Peter; Locke, Adam E.; Fuchsberger, Christian; Stringham, Heather M.; Welch, Ryan; Yu, Ketian; Silva, Lilian Fernandes; Service, Susan K.; Zhang, Daiwei; Hector, Emily C.; Young, Erica; Ganel, Liron; Das, Indraniel; Abel, Haley; Erdos, Michael R.; Bonnycastle, Lori L.; Kuusisto, Johanna; Stitziel, Nathan O.; Hall, Ira M.; Wagner, Gregory R.; Kang, Jian; Morrison, Jean; Burant, Charles F.; Collins, Francis S.; Ripatti, Samuli; Palotie, Aarno; Freimer, Nelson B.; Mohlke, Karen L.; Scott, Laura J.; Wen, Xiaoquan; Fauman, Eric B.; Laakso, Markku; Boehnke, Michael 分享 收藏
Multiparametric platform for profiling lipid trafficking in human leukocytes 用于分析人类白细胞中脂质运输的多参数平台 Pfisterer, Simon G.; Brock, Ivonne; Kanerva, Kristiina; Hlushchenko, Iryna; Paavolainen, Lassi; Ripatti, Pietari; Islam, Mohammad Majharul; Kyttala, Aija; Di Taranto, Maria D.; di Frega, Annalisa Scotto; Fortunato, Giuliana; Kuusisto, Johanna; Horvath, Peter; Ripatti, Samuli; Laakso, Markku; Ikonen, Elina 分享 收藏
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Subcutaneous adipose tissue splice quantitative trait loci reveal differences in isoform usage associated with cardiometabolic traits Brotman, Sarah M.; Raulerson, Chelsea K.; Vadlamudi, Swarooparani; Currin, Kevin W.; Shen, Qiujin; Parsons, Victoria A.; Iyengar, Apoorva K.; Roman, Tamara S.; Furey, Terrence S.; Kuusisto, Johanna; Collins, Francis S.; Boehnke, Michael; Laakso, Markku; Pajukanta, Paivi; Mohlke, Karen L. 分享 收藏
Rare coding variants in 35 genes associate with circulating lipid levels-A multi-ancestry analysis of 170,000 exomes 35个基因的罕见编码变异与循环脂质水平相关 -- 170,000外显子组的多祖先分析 Hindy, George; Dornbos, Peter; Chaffin, Mark D.; Liu, Dajiang J.; Wang, Minxian; Selvaraj, Margaret Sunitha; Zhang, David; Park, Joseph; Aguilar-Salinas, Carlos A.; Antonacci-Fulton, Lucinda; Ardissino, Diego; Arnett, Donna K.; Aslibekyan, Stella; Atzmon, Gil; Ballantyne, Christie M.; Barajas-Olmos, Francisco; Barzilai, Nir; Becker, Lewis C.; Bielak, Lawrence F.; Bis, Joshua C.; Blangero, John; Boerwinkle, Eric; Bonnycastle, Lori L.; Bottinger, Erwin; Bowden, Donald W.; Bown, Matthew J.; Brody, Jennifer A.; Broome, Jai G.; Burtt, Noel P.; Cade, Brian E.; Centeno-Cruz, Federico; Chan, Edmund; Chang, Yi-Cheng; Chen, Yii-Der I.; Cheng, Ching-Yu; Choi, Won Jung; Chowdhury, Rajiv; Contreras-Cubas, Cecilia; Cordova, Emilio J.; Correa, Adolfo; Cupples, L. Adrienne; Curran, Joanne E.; Danesh, John; de Vries, Paul S.; DeFronzo, Ralph A.; Doddapaneni, Harsha; Duggirala, Ravindranath; Dutcher, Susan K.; Ellinor, Patrick T.; Emery, Leslie S.; Florez, Jose C.; Fornage, Myriam; Freedman, Barry I.; Fuster, Valentin; Garay-Sevilla, Ma. Eugenia; Garcia-Ortiz, Humberto; Germer, Soren; Gibbs, Richard A.; Gieger, Christian; Glaser, Benjamin; Gonzalez, Clicerio; Gonzalez-Villalpando, Maria Elena; Graff, Mariaelisa; Graham, Sarah E.; Grarup, Niels; Groop, Leif C.; Guo, Xiuqing; Gupta, Namrata; Han, Sohee; Hanis, Craig L.; Hansen, Torben; He, Jiang; Heard-Costa, Nancy L.; Hung, Yi-Jen; Hwang, Mi Yeong; Irvin, Marguerite R.; Islas-Andrade, Sergio; Jarvik, Gail P.; Kang, Hyun Min; Kardia, Sharon L. R.; Kelly, Tanika; Kenny, Eimear E.; Khan, Alyna T.; Kim, Bong-Jo; Kim, Ryan W.; Kim, Young Jin; Koistinen, Heikki A.; Kooperberg, Charles; Kuusisto, Johanna; Kwak, Soo Heon; Laakso, Markku; Lange, Leslie A.; Lee, Jiwon; Lee, Juyoung; Lee, Seonwook; Lehman, Donna M.; Lemaitre, Rozenn N.; Linneberg, Allan; Liu, Jianjun; Loos, Ruth J. F.; Lubitz, Steven A.; Lyssenko, Valeriya; Ma, Ronald C. W.; Martin, Lisa Warsinger; Martinez-Hernandez, Angelica; Mathias, Rasika A.; McGarvey, Stephen T.; McPherson, Ruth; Meigs, James B.; Meitinger, Thomas; Melander, Olle; Mendoza-Caamal, Elvia; Metcalf, Ginger A.; Mi, Xuenan; Mohlke, Karen L.; Montasser, May E.; Moon, Jee-Young; Moreno-Macias, Hortensia; Morrison, Alanna C.; Muzny, Donna M.; Nelson, Sarah C.; Nilsson, Peter M.; O'Connell, Jeffrey R.; Orho-Melander, Marju; Orozco, Lorena; Palmer, Colin N. A.; Palmer, Nicholette D.; Park, Cheol Joo; Park, Kyong Soo; Pedersen, Oluf; Peralta, Juan M.; Peyser, Patricia A.; Post, Wendy S.; Preuss, Michael; Psatsy, Bruce M.; Qi, Qibin; Rao, D. C.; Redline, Susan; Reiner, Alexander P.; Revilla-Monsalve, Cristina; Rich, Stephen S.; Samani, Nilesh; Schunkert, Heribert; Schurmann, Claudia; Seo, Daekwan; Seo, Jeong-Sun; Sim, Xueling; Sladek, Rob; Small, Kerrin S.; So, Wing Yee; Stilp, Adrienne M.; Tai, E. Shyong; Tam, Claudia H. T.; Taylor, Kent D.; Teo, Yik Ying; Thameem, Farook; Tomlinson, Brian; Tsai, Michael Y.; Tuomi, Tiinamaij; Tuomilehto, Jaakko; Tusie-Luna, Teresa; Udler, Miriam S.; van Dam, Rob M.; Vasan, Ramachandran S.; Martinez, Karine A. Viaud; Wang, Fei Fei; Wang, Xuzhi; Watkins, Hugh; Weeks, Daniel E.; Wilson, James G.; Witte, Daniel R.; Wong, Tien-Yin; Yanek, Lisa R.; Kathiresan, Sekar; Rader, Daniel J.; Rotter, Jerome I.; Boehnke, Michael; McCarthy, Mark I.; Willer, Cristen J.; Natarajan, Pradeep; Flannick, Jason A.; Khera, Amit V.; Peloso, Gina M. 分享 收藏
Microglia-like Cells Promote Neuronal Functions in Cerebral Organoids Fagerlund, Ilkka; Dougalis, Antonios; Shakirzyanova, Anastasia; Gomez-Budia, Mireia; Pelkonen, Anssi; Konttinen, Henna; Ohtonen, Sohvi; Fazaludeen, Mohammad Feroze; Koskuvi, Marja; Kuusisto, Johanna; Hernandez, Damian; Pebay, Alice; Koistinaho, Jari; Rauramaa, Tuomas; Lehtonen, Sarka; Korhonen, Paula; Malm, Tarja 分享 收藏
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Determinants of penetrance and variable expressivity in monogenic metabolic conditions across 77,184 exomes 跨77,184外显子组的单基因代谢条件下的外显率和可变表现率的决定因素 Goodrich, Julia K.; Singer-Berk, Moriel; Son, Rachel; Sveden, Abigail; Wood, Jordan; England, Eleina; Cole, Joanne B.; Weisburd, Ben; Watts, Nick; Caulkins, Lizz; Dornbos, Peter; Koesterer, Ryan; Zappala, Zachary; Zhang, Haichen; Maloney, Kristin A.; Dahl, Andy; Aguilar-Salinas, Carlos A.; Atzmon, Gil; Barajas-Olmos, Francisco; Barzilai, Nir; Blangero, John; Boerwinkle, Eric; Bonnycastle, Lori L.; Bottinger, Erwin; Bowden, Donald W.; Centeno-Cruz, Federico; Chambers, John C.; Chami, Nathalie; Chan, Edmund; Chan, Juliana; Cheng, Ching-Yu; Cho, Yoon Shin; Contreras-Cubas, Cecilia; Cordova, Emilio; Correa, Adolfo; DeFronzo, Ralph A.; Duggirala, Ravindranath; Dupuis, Josee; Eugenia Garay-Sevilla, Ma; Garcia-Ortiz, Humberto; Gieger, Christian; Glaser, Benjamin; Gonzalez-Villalpando, Clicerio; Elena Gonzalez, Ma; Grarup, Niels; Groop, Leif; Gross, Myron; Haiman, Christopher; Han, Sohee; Hanis, Craig L.; Hansen, Torben; Heard-Costa, Nancy L.; Henderson, Brian E.; Hernandez, Juan Manuel Malacara; Hwang, Mi Yeong; Islas-Andrade, Sergio; Jorgensen, Marit E.; Kang, Hyun Min; Kim, Bong-Jo; Kim, Young Jin; Koistinen, Heikki A.; Kooner, Jaspal Singh; Kuusisto, Johanna; Kwak, Soo-Heon; Laakso, Markku; Lange, Leslie; Lee, Jong-Young; Lee, Juyoung; Lehman, Donna M.; Linneberg, Allan; Liu, Jianjun; Loos, Ruth J. F.; Lyssenko, Valeriya; Ma, Ronald C. W.; Martinez-Hernandez, Angelica; Meigs, James B.; Meitinger, Thomas; Mendoza-Caamal, Elvia; Mohlke, Karen L.; Morris, Andrew D.; Morrison, Alanna C.; Ng, Maggie C. Y.; Nilsson, Peter M.; O'Donnell, Christopher J.; Orozco, Lorena; Palmer, Colin N. A.; Park, Kyong Soo; Post, Wendy S.; Pedersen, Oluf; Preuss, Michael; Psaty, Bruce M.; Reiner, Alexander P.; Revilla-Monsalve, Cristina; Rich, Stephen S.; Rotter, Jerome I.; Saleheen, Danish; Schurmann, Claudia; Sim, Xueling; Sladek, Rob; Small, Kerrin S.; So, Wing Yee; Spector, Timothy D.; Strauch, Konstantin; Strom, Tim M.; Tai, E. Shyong; Tam, Claudia H. T.; Teo, Yik Ying; Thameem, Farook; Tomlinson, Brian; Tracy, Russell P.; Tuomi, Tiinamaija; Tuomilehto, Jaakko; Tusie-Luna, Teresa; van Dam, Rob M.; Vasan, Ramachandran S.; Wilson, James G.; Witte, Daniel R.; Wong, Tien-Yin; Burtt, Noel P.; Zaitlen, Noah; McCarthy, Mark I.; Boehnke, Michael; Pollin, Toni I.; Flannick, Jason; Mercader, Josep M.; O'Donnell-Luria, Anne; Baxter, Samantha; Florez, Jose C.; MacArthur, Daniel G.; Udler, Miriam S. 分享 收藏
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