Robert L. Eoff - Publications, H-index & Citations

Robert L. Eoff

University of Arkansas System

30H指数

120论文数

2.7K被引数

收录论文 56

发表时间

Evaluation of the Activity of Monensin and Its Analogs for Modulation of Stem-like Cell Functionality in 2D and 3D Breast Cancer Models

ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE

IF3.7

2025-10-01

PREAI

Urbaniak, Alicja; Heflin, Billie; Siegel, Eric R.; Seale, Drew; Reed, Megan R.; Nix, James S.; Yee, Eric U.; Jedrzejczyk, Marta; Klejborowska, Greta; Stepczynska, Natalia; Huczynski, Adam; Nagalo, Bolni M.; Chambers, Timothy C.; Post, Steven R.; Eoff, Robert L.; Macnicol, Melanie C.; Tiwari, Amit K.; Kelly, Thomas; Tackett, Alan J.; MacNicol, Angus M.

DNA polymerase kappa (Pol k) promotes replication gap suppression by preventing PrimPol mediated repriming and safeguards genomic stability in Glioblastoma Multiforme (GBM)

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2024-03-01

OAAI

Sewilam, Reham; Reed, Megan; Eoff, Robert

Conservation of the insert-2 motif confers Rev1 from different species with an ability to disrupt G-quadruplexes and stimulate translesion DNA synthesis

RSC CHEMICAL BIOLOGY

IF3.1

2023-01-01

OAAI

Ketkar, Amit; Sewilam, Reham S.; McCrury, Mason J.; Hall, Jaycelyn S.; Bell, Ashtyn; Paxton, Bethany C.; Tripathi, Shreyam; Gunderson, Julie E. C.; Eoff, Robert L.

Anti-glioblastoma activity of monensin and its analogs in an organoid model of cancer

BIOMEDICINE & PHARMACOTHERAPY

IF7.5

2022-09-01

OAAI

Urbaniak, Alicja; Reed, Megan R.; Heflin, Billie; Gaydos, John; Pina-Oviedo, Sergio; Jedrzejczyk, Marta; Klejborowska, Greta; Stepczynska, Natalia; Chambers, Timothy C.; Tackett, Alan J.; Rodriguez, Analiz; Huczynski, Adam; Eoff, Robert L.; MacNicol, Angus M.

Site-Specific Synthesis of Oligonucleotides Containing 6-Oxo-M1dG, the Genomic Metabolite of M1dG, and Liquid Chromatography-Tandem Mass Spectrometry Analysis of Its In Vitro Bypass by Human Polymerase ι

CHEMICAL RESEARCH IN TOXICOLOGY

IF3.8

2021-12-03

OAAI

Christov, Plamen P.; Richie-Jannetta, Robyn; Kingsley, Philip J.; Vemulapalli, Anoop; Kim, Kwangho; Sulikowski, Gary A.; Rizzo, Carmelo J.; Ketkar, Amit; Eoff, Robert L.; Rouzer, Carol A.; Marnett, Lawrence J.

A Functional Precision Medicine Pipeline Combines Comparative Transcriptomics and Tumor Organoid Modeling to Identify Bespoke Treatment Strategies for Glioblastoma

CELLS

IF5.2

2021-12-02

OAAI

Reed, Megan R.; Lyle, A. Geoffrey; De Loose, Annick; Maddukuri, Leena; Learned, Katrina; Beale, Holly C.; Kephart, Ellen T.; Cheney, Allison; van den Bout, Anouk; Lee, Madison P.; Hundley, Kelsey N.; Smith, Ashley M.; DesRochers, Teresa M.; Vibat, Cecile Rose T.; Gokden, Murat; Salama, Sofie; Wardell, Christopher P.; Eoff, Robert L.; Vaske, Olena M.; Rodriguez, Analiz

Inositol serves as a natural inhibitor of mitochondrial fission by directly targeting AMPK 肌醇通过直接靶向AMPK作为线粒体分裂的天然抑制剂

MOLECULAR CELL

IF16.6

2021-09-01

OAAI

Hsu, Che-Chia; Zhang, Xian; Wang, Guihua; Zhang, Weina; Cai, Zhen; Pan, Bo-Syong; Gu, Haiwei; Xu, Chuan; Jin, Guoxiang; Xu, Xiangshang; Manne, Rajesh Kumar; Jin, Yan; Yan, Wei; Shao, Jingwei; Chen, Tingjin; Lin, Emily; Ketkar, Amit; Eoff, Robert; Xu, Zhi-Gang; Chen, Zhong-Zhu; Li, Hong-Yu; Lin, Hui-Kuan

Single and double modified salinomycin analogs target stem-like cells in 2D and 3D breast cancer models

BIOMEDICINE & PHARMACOTHERAPY

IF7.5

2021-09-01

OAAI

Urbaniak, Alicja; Reed, Megan R.; Fil, Daniel; Moorjani, Anika; Heflin, Sarah; Antoszczak, Michal; Sulik, Michal; Huczynski, Adam; Kupsik, Michalina; Eoff, Robert L.; MacNicol, Melanie C.; Chambers, Timothy C.; MacNicol, Angus M.

Selective Binding Of Human Rev1 With G-Quadruplex DNA Is Determined By A Region Unique to Higher Eukaryotes

FASEB JOURNAL

IF4.2

2021-05-14

OAAI

Ketkar, Amit; Smith, Lane; Johnson, Callie; Richey, Alyssa; Berry, Makayla; Hartman, Jessica; Maddukuri, Leena; Reed, Megan; Gunderson, Julie; Leung, Justin; Eoff, Robert

DNA Polymerase Kappa Acts as a Barrier to Unrestrained Replication in Glioblastoma

FASEB JOURNAL

IF4.2

2021-05-14

PREAI

Reed, Megan; Maddukuri, Leena; Ketkar, Amit; Zafar, Maroof; Leung, Justin; Rodriguez, Analiz; Eoff, Robert

Deletion of putative xenobiotic response elements (XREs) in hpol κ alters the replication stress response and overall genomic instability in glioblastoma cells

FASEB JOURNAL

IF4.2

2021-05-14

PREAI

Maddukuri, Leena; Reed, Megan; Ketkar, Amit; Leung, Justin; Eoff, Robert

Inhibition of tryptophan 2,3-dioxygenase impairs DNA damage tolerance and repair in glioma cells

NAR CANCER

IF3.2

2021-04-09

OAAI

Reed, Megan R.; Maddukuri, Leena; Ketkar, Amit; Byrum, Stephanie D.; Zafar, Maroof K.; Bostian, April C. L.; Tackett, Alan J.; Eoff, Robert L.

Human Rev1 relies on insert-2 to promote selective binding and accurate replication of stabilized G-quadruplex motifs

NUCLEIC ACIDS RESEARCH

IF13.1

2021-02-08

OAAI

Ketkar, Amit; Smith, Lane; Johnson, Callie; Richey, Alyssa; Berry, Makayla; Hartman, Jessica H.; Maddukuri, Leena; Reed, Megan R.; Gunderson, Julie E. C.; Leung, Justin W. C.; Eoff, Robert L.

A Facile Semisynthesis and Evaluation of Garcinoic Acid and Its Analogs for the Inhibition of Human DNA Polymerase β

MOLECULES

IF4.6

2020-12-11

OAAI

Gujarathi, Satheesh; Zafar, Maroof Khan; Liu, Xingui; Eoff, Robert L.; Zheng, Guangrong

Novel Salinomycin Analogs Show Improved Selectivity Towards Breast Cancer Stem Cells

FASEB JOURNAL

IF4.2

2020-04-18

OAAI

Urbaniak, Alicja; Reed, Megan; Antoszczak, Michal; Sulik, Michal; Huczynski, Adam; Eoff, Robert; MacNicol, Melanie; MacNicol, Angus; Chambers, Timothy

Inhibition of Human DNA Polymerases Eta and Kappa by Indole-Derived Molecules Occurs through Distinct Mechanisms

ACS CHEMICAL BIOLOGY

IF3.8

2019-05-13

OAAI

Ketkar, Amit; Maddukuri, Leena; Penthala, Narsimha R.; Reed, Megan R.; Zafar, Maroof K.; Crooks, Peter A.; Eoff, Robert L.

LC8/DYNLL1 is a 53BP1 effector and regulates checkpoint activation

NUCLEIC ACIDS RESEARCH

IF13.1

2019-04-15

OAAI

West, Kirk L.; Kelliher, Jessica L.; Xu, Zhanzhan; An, Liwei; Reed, Megan R.; Eoff, Robert L.; Wang, Jiadong; Huen, Michael S. Y.; Leung, Justin W. C.

Translesion DNA Synthesis in Cancer: Molecular Mechanisms and Therapeutic Opportunities

CHEMICAL RESEARCH IN TOXICOLOGY

IF3.8

2017-09-28

OAAI

Zafar, Maroof K.; Eoff, Robert L.

A catch and release program for single-stranded DNA

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2017-08-01

OAAI

Eoff, Robert L.; Raney, Kevin D.