Paul B. Mullan - Publications, H-index & Citations

Paul B. Mullan

the all-ireland cancer liquid biopsies consortium (club)

35H指数

116论文数

5.3K被引数

收录论文 51

发表时间

Unbiased combination screening on repurposed drugs reveals synergistic potential of copanlisib and cerivastatin against chemoresistant high-grade serous ovarian cancer 对再利用药物进行无偏组合筛选，揭示了copanlisib和cerivastatin对化疗耐药性高级别浆液性卵巢癌的协同潜力

Journal of Ovarian Research

IF4.2

2025-11-08

OAAI

Yu Sun; Yangyang Wang; Syed Umbreen; Benjamin Pepperrell; Niamh Buckley; Paul Mullan; Ahlam Ali; Fiona Furlong

A SRC-slug-TGFβ2 signaling axis drives poor outcomes in triple-negative breast cancers

CELL COMMUNICATION AND SIGNALING

IF8.9

2024-09-26

OAAI

Angel, Charlotte Zoe; Beattie, Shannon; Hanif, Ezanee Azlina Mohamad; Ryan, Micheal P.; Guerra Liberal, Francisco D. C.; Zhang, Shu-Dong; Monteith, Scott; Buckley, Niamh E.; Parker, Emma; Haynes, Shannon; Mcintyre, Alexander J.; Haddock, Paula; Sharifova, Madina; Branco, Cristina M.; Mullan, Paul B.

TBX2 acts as a potent transcriptional silencer of tumour suppressor genes through interaction with the CoREST complex to sustain the proliferation of breast cancers

NUCLEIC ACIDS RESEARCH

IF13.1

2022-06-10

OAAI

McIntyre, Alexander J.; Angel, Charlotte Z.; Smith, James S.; Templeman, Amy; Beattie, Katherine; Beattie, Shannon; Ormrod, Alice; Devlin, Eadaoin; McGreevy, Charles; Bothwell, Chloe; Eddie, Sharon L.; Buckley, Niamh E.; Williams, Rich; Mullan, Paul B.

USP17 is required for peripheral trafficking of lysosomes

EMBO REPORTS

IF6.2

2022-01-26

OAAI

Lin, Jia; McCann, Aidan P.; Sereesongsaeng, Naphannop; Burden, Jonathan M.; Alsa'd, Alhareth A.; Burden, Roberta E.; Micu, Ileana; Williams, Richard; Van Schaeybroeck, Sandra; Evergren, Emma; Mullan, Paul; Simpson, Jeremy C.; Scott, Christopher J.; Burrows, James F.

Pin1 plays a key role in the response to treatment and clinical outcome in triple negative breast cancer

THERAPEUTIC ADVANCES IN MEDICAL ONCOLOGY

IF4.2

2020-03-09

OAAI

Knowlson, Catherine; Haddock, Paula; Bingham, Victoria; McQuaid, Stephen; Mullan, Paul B.; Buckley, Niamh E.

TBX2 interacts with heterochromatin protein 1 to recruit a novel repression complex to EGR1-targeted promoters to drive the proliferation of breast cancer cells

ONCOGENE

IF7.3

2019-06-28

OAAI

Crawford, N. T.; McIntyre, A. J.; McCormick, A.; D'Costa, Z. C.; Buckley, N. E.; Mullan, P. B.

NUP98-a novel predictor of response to anthracycline-based chemotherapy in triple negative breast cancer NUP98-a三阴性乳腺癌中基于蒽环类药物的化疗反应的新预测因子

BMC CANCER

IF3.4

2019-04-02

OAAI

Mullan, Paul B.; Bingham, Victoria; Haddock, Paula; Irwin, Gareth W.; Kay, Elaine; McQuaid, Stephen; Buckley, Niamh E.

Legumain regulates advanced prostate cancer via HSD17B4

CANCER RESEARCH

IF16.6

2018-07-01

PREAI

Eddie, Sharon L.; Ormrod, Alice V.; Williams, Rich; Mullan, Paul B.

Generation of a transcriptome of oncogenic mutant p53 in triple-negative breast cancer

CANCER RESEARCH

IF16.6

2017-07-01

PREAI

Steele, Rebecca E.; McDade, Simon S.; Mullan, Paul B.

The role of Pin1 in chemosensitivity of BRCA1-deficient breast cancers

CANCER RESEARCH

IF16.6

2017-07-01

PREAI

Knowlson, Catherine; Mullan, Paul; Buckley, Niamh

Activation of STING-Dependent Innate Immune Signaling By S-Phase-Specific DNA Damage in Breast Cancer 乳腺癌中S期特异性DNA损伤激活STING依赖性先天免疫信号

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE

IF7.2

2016-10-05

344

OAAI

Parkes, Eileen E.; Walker, Steven M.; Taggart, Laura E.; McCabe, Nuala; Knight, Laura A.; Wilkinson, Richard; McCloskey, Karen D.; Buckley, Niamh E.; Savage, Kienan I.; Salto-Tellez, Manuel; McQuaid, Stephen; Harte, Mary T.; Mullan, Paul B.; Harkin, D. Paul; Kennedy, Richard D.

A BRCA1 deficient, NFKB driven immune signal predicts good outcome in triple negative breast cancer

CANCER RESEARCH

IF16.6

2016-07-15

PREAI

Buckley, Niamh E.; Haddock, Paula; Simoes, Ricardo De Matos; Parkes, Eileen; Irwin, Gareth; Emmert-Streib, Frank; McQuaid, Stephen; Kennedy, Richard D.; Mullan, Paul B.

A DNA damage response deficiency (DDRD) group in breast cancer is associated with activation of the STING innate immune pathway and PD-L1 expression

CANCER RESEARCH

IF16.6

2016-07-15

PREAI

Parkes, Eileen E.; Walker, Steven M.; McCabe, Nuala; Taggart, Laura E.; Hill, Laura; Buckley, Niamh E.; Savage, Kienan I.; Salto-Tellez, Manuel; McQuaid, Stephen; Harte, Mary T.; Mullan, Paul B.; Harkin, D. Paul; Kennedy, Richard D.

Quantification of HER2 heterogeneity in breast cancer-implications for identification of sub-dominant clones for personalised treatment

SCIENTIFIC REPORTS

IF3.9

2016-03-21

OAAI

Buckley, Niamh E.; Forde, Claire; McArt, Darragh G.; Boyle, David P.; Mullan, Paul B.; James, Jacqueline A.; Maxwell, Perry; McQuaid, Stephen; Salto-Tellez, Manuel

Characterization of a novel BRCA1-EGR1 interaction

CANCER RESEARCH

IF16.6

2015-08-01

PREAI

Dickson, Naomi A.; Crawford, Nyree T.; Mullan, Paul B.

PICan: An integromics framework for dynamic cancer biomarker discovery PICan: 动态癌症生物标志物发现的整合框架

MOLECULAR ONCOLOGY

IF4.5

2015-03-04

OAAI

McArt, Darragh G.; Blayney, Jaine K.; Boyle, David P.; Irwin, Gareth W.; Moran, Michael; Hutchinson, Ryan A.; Bankhead, Peter; Kieran, Declan; Wang, Yinhai; Dunne, Philip D.; Kennedy, Richard D.; Mullan, Paul B.; Harkin, D. Paul; Catherwood, Mark A.; James, Jacqueline A.; Salto-Tellez, Manuel; Hamilton, Peter W.

Analysis of wntless (WLS) expression in gastric, ovarian, and breast cancers reveals a strong association with HER2 overexpression

MODERN PATHOLOGY

IF5.5

2015-03-01

OAAI

Stewart, Jonathan; James, Jacqueline; McCluggage, Glenn W.; McQuaid, Stephen; Arthur, Kenneth; Boyle, David; Mullan, Paul; McArt, Darragh; Yan, Benedict; Irwin, Gareth; Harkin, D. Paul; Lei Zhengdeng; Ongl, Chee-Wee; Yu, Jia; Virshup, David M.; Salto-Tellez, Manuel

Defining a therapeutic classification of breast cancer by actionable targets

CANCER RESEARCH

IF16.6

2014-10-01

PREAI

Salto-Tellez, Manuel; Boyle, David P.; McArt, Darragh; Irwin, Gareth; Wilhelm-Benartzi, Charlotte Charlotte; Lioe, Tong G.; Minter, Martha; McQuaid, Stephen; Mullan, Paul; Kennedy, Richard D.; Hamilton, Peter; Harkin, D. P.

A novel cell growth control pathway repressed by the oncogene TBX2 in breast cancer cells

MOLECULAR CANCER RESEARCH

IF4.7

2014-07-31

PREAI

D'Costa, Zenobia Carmel; Higgins, Catherine A.; Williams, Richard; Mullan, Paul B.

The prognostic significance of the aberrant extremes of p53 immunophenotypes in breast cancer

HISTOPATHOLOGY

IF4.1

2014-04-16

PREAI

Boyle, David P.; McArt, Darragh G.; Irwin, Gareth; Wilhelm-Benartzi, Charlotte S.; Lioe, Tong F.; Sebastian, Elena; McQuaid, Stephen; Hamilton, Peter W.; James, Jacqueline A.; Mullan, Paul B.; Catherwood, Mark A.; Harkin, D. Paul; Salto-Tellez, Manuel

研究方向