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Assessment of genetic polymorphisms within nuclear factor-xB signaling pathway genes in rheumatoid arthritis: Evidence for replication and genetic interaction 类风湿关节炎中核因子-xB信号通路基因的遗传多态性评估: 复制和遗传相互作用的证据 Zeng, Zhen; Sun, Qing-Qing; Zhang, Wei; Wen, Qin-Wen; Wang, Ting-Hui; Qin, Wen; Xiao, Dong-Mei; Zhang, Zhen; Huang, Hua; Mo, Yi-Jun; Wu, Xiu-Di; Cen, Han 分享 收藏
The Dolaflexin-based Antibody-Drug Conjugate XMT-1536 Targets the Solid Tumor Lineage Antigen SLC34A2/NaPi2b Bodyak, Natalya D.; Mosher, Rebecca; Yurkovetskiy, Aleksandr, V; Yin, Mao; Bu, Charlie; Conlon, Patrick R.; Demady, Damon R.; DeVit, Michael J.; Gumerov, Dmitry R.; Gurijala, Venu R.; Lee, Winnie; McGillicuddy, Dennis; Park, Peter U.; Poling, Laura L.; Protopova, Marina; Qin, LiuLiang; Stevenson, Cheri A.; Ter-Ovanesyan, Elena; Uttard, Alex; Xiao, Dongmei; Xu, Jian; Xu, Ling; Bergstrom, Donald A.; Lowinger, Timothy B. 分享 收藏
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Discovery and preclinical development of a highly potent NaPi2b-targeted antibody -drug conjugate (ADC) with significant activity in patient -derived non -small cell lung cancer (NSCLC) xenograft models Bodyak, Natalya; Yurkovetskiy, Alex; Yin, Mao; Gumerov, Dmitry; Bollu, Reddy; Conlon, Patrick; Gurijala, Venu R.; McGillicuddy, Dennis; Stevenson, Cheri; Ter-Ovanesyan, Elena; Park, Peter U.; Poling, Laura; Lee, Winnie; Devit, Michael; Xiao, Dongmei; Qin, LiuLiang; Lowinger, Timothy B.; Bergstrom, Donald A. 分享 收藏
Optimization of lead antibody selection for XMT-1522, a novel, highly potent HER2-targeted antibody-drug conjugate (ADC) Bodyak, Natasha; Yurkovetskiy, Alex; Gumerov, Dmitry R.; Xiao, Dongmei; Thomas, Joshua D. Thomad D.; Poling, Laura L.; Qin, LiuLiang; Yin, Mao; DeVit, Michael J.; Park, Peter U.; Lee, Winnie; Prinz, Bianka; Bergstrom, Donald A.; Lowinger, Timothy B. 分享 收藏
XMT-1522 induces tumor regressions in pre-clinical models representing HER2-positive and HER2 low-expressing breast cancer Bergstrom, D. A.; Bodyak, N.; Park, P. U.; Yurkovetskiy, A.; DeVit, M.; Yin, M.; Poling, L.; Thomas, J. D.; Gumerov, D.; Xiao, D.; Ter-Ovanesyan, E.; Qin, L.; Uttard, A.; Johnson, A.; Lowinger, T. B. 分享 收藏
A novel, highly potent HER2-targeted antibody-drug conjugate (ADC) for the treatment of low HER2-expressing tumors and combination with trastuzumab-based regimens in HER2-driven tumors Bergstrom, Donald A.; Bodyak, Natalya; Yurkovetskiy, Alex; Park, Peter U.; DeVit, Michael; Yin, Mao; Poling, Laura; Thomas, Joshua D.; Gumerov, Dmitry; Xiao, Dongmei; Ter-Ovanesyan, Elena; Qin, LiuLiang; Uttard, Alex; Johnson, Alex; Lowinger, Timothy B. 分享 收藏
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Prediction of xenograft response to MM-121, an anti-ErbB3 inhibitor, using computational modeling and measurements of five biomarkers Onsum, Matthew; Burenkova, Olga; Fulgham, Aaron; Nie, Lin; Kalra, Ashish; Xiao, Dongmei; Grantcharova, Viara; Adams, Sharlene; Luus, Lia; Paragas, Violette; Bukhalid, Raghida; Moulis, Sharon; Wille, Lucia; Garcia, Gabriela; Moyo, Victor; Schoeberl, Birgit; Kubasek, Bill; Nielsen, Ulrik 分享 收藏
Efficacy of MM121 in ER+ and triple negative breast cancer studies Nie, Lin; Burenkova, Olga; Adams, Sharlene; Kalra, Ashish; Fulgham, Aaron; Xiao, Dongmei; Grantcharova, Viara; Onsum, Matt; Wille, Lucia; Moulis, Sharon; Garcia, Gabriela; Moyo, Victor; Kubasek, Bill; Nielsen, Ulrik 分享 收藏