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Lenvatinib plus Pembrolizumab Following Immune Checkpoint Inhibitor Treatment in Patients with Metastatic Clear Cell Renal Cell Carcinoma: Results from Study 111/KEYNOTE-146 仑伐替尼联合帕博利珠单抗在免疫检查点抑制剂治疗后转移性透明细胞肾细胞癌患者中的应用：Study 111/KEYNOTE-146研究的结果 Lee, Chung-Han; Shah, Amishi Yogesh; Rao, Arpit; Taylor, Matthew H.; Di Simone, Christopher; Hsieh, James J.; Pinto, Alvaro; Sarrio, Regina Girones; Cohn, Allen Lee; Bilen, Mehmet Asim; Ribe, Sara Gunnestad; Tennoe, Oyvind Krohn; Richards, Donald; Sweis, Randy F.; Courtright, Jay; Heinrich, Daniel; Perini, Rodolfo; Kubiak, Peter; Bock, Daena; Okpara, Chinyere E. 分享 收藏
The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma (vol 23, pg 313, 2018) 肾细胞癌的癌症基因组图谱综合分子特征 (第23卷，313页，2018) Ricketts, Christopher J.; De Cubas, Aguirre A.; Fan, Huihui; Smith, Christof C.; Lang, Martin; Reznik, Ed; Bowlby, Reanne; Gibb, Ewan A.; Akbani, Rehan; Beroukhim, Rameen; Bottaro, Donald P.; Choueiri, Toni K.; Gibbs, Richard A.; Godwin, Andrew K.; Haake, Scott; Hakimi, A. Ari; Henske, Elizabeth P.; Hsieh, James J.; Ho, Thai H.; Kanchi, Rupa S.; Krishnan, Bhavani; Kwiatkowski, David J.; Liu, Wenbin; Merino, Maria J.; Mills, Gordon B.; Myers, Jerome; Nickerson, Michael L.; Reuter, Victor E.; Schmidt, Laura S.; Shelley, C. Simon; Shen, Hui; Shuch, Brian; Signoretti, Sabina; Srinivasan, Ramaprasad; Tamboli, Pheroze; Thomas, George; Vincent, Benjamin G.; Vocke, Cathy D.; Wheeler, David A.; Yang, Lixing; Kim, William Y.; Robertson, A. Gordon; Spellman, Paul T.; Rathmell, W. Kimryn; Linehan, W. Marston 分享 收藏
Combining the Tyrosine Kinase Inhibitor Cabozantinib and the mTORC1/2 Inhibitor Sapanisertib Blocks ERK Pathway Activity and Suppresses Tumor Growth in Renal Cell Carcinoma Wu, Yige; Chen, Siqi; Yang, Xiaolu; Sato, Kazuhito; Lal, Preet; Wang, Yuefan; Shinkle, Andrew T.; Wendl, Michael C.; Primeau, Tina M.; Zhao, Yanyan; Gould, Alanna; Sun, Hua; Mudd, Jacqueline L.; Hoog, Jeremy; Mashl, R. Jay; Wyczalkowski, Matthew A.; Mo, Chia-Kuei; Liu, Ruiyang; Herndon, John M.; Davies, Sherri R.; Liu, Di; Ding, Xi; Evrard, Yvonne A.; Welm, Bryan E.; Lum, David; Koh, Mei Yee; Welm, Alana L.; Chuang, Jeffrey H.; Moscow, Jeffrey A.; Meric-Bernstam, Funda; Govindan, Ramaswamy; Li, Shunqiang; Hsieh, James; Fields, Ryan C.; Lim, Kian-Huat; Ma, Cynthia X.; Zhang, Hui; Ding, Li; Chen, Feng 分享 收藏
Epigenetic and transcriptomic characterization reveals progression markers and essential pathways in clear cell renal cell carcinoma (vol 14, 1681, 2023) Wu, Yige; Terekhanova, Nadezhda V.; Caravan, Wagma; Al Deen, Nataly Naser; Lal, Preet; Chen, Siqi; Mo, Chia-Kuei; Cao, Song; Li, Yize; Karpova, Alla; Liu, Ruiyang; Zhao, Yanyan; Shinkle, Andrew; Strunilin, Ilya; Weimholt, Cody; Sato, Kazuhito; Yao, Lijun; Serasanambati, Mamatha; Yang, Xiaolu; Wyczalkowski, Matthew; Zhu, Houxiang; Zhou, Daniel Cui; Jayasinghe, Reyka G.; Mendez, Daniel; Wendl, Michael C.; Clark, David; Newton, Chelsea; Ruan, Yijun; Reimers, Melissa A.; Pachynski, Russell K.; Kinsinger, Chris; Jewell, Scott; Chan, Daniel W.; Zhang, Hui; Chaudhuri, Aadel A.; Chheda, Milan G.; Humphreys, Benjamin D.; Mesri, Mehdi; Rodriguez, Henry; Hsieh, James J.; Ding, Li; Chen, Feng 分享 收藏
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Epigenetic and transcriptomic characterization reveals progression markers and essential pathways in clear cell renal cell carcinoma Wu, Yige; Terekhanova, Nadezhda V.; Caravan, Wagma; Al Deen, Nataly Naser; Lal, Preet; Chen, Siqi; Mo, Chia-Kuei; Cao, Song; Li, Yize; Karpova, Alla; Liu, Ruiyang; Zhao, Yanyan; Shinkle, Andrew; Strunilin, Ilya; Weimholt, Cody; Sato, Kazuhito; Yao, Lijun; Serasanambati, Mamatha; Yang, Xiaolu; Wyczalkowski, Matthew; Zhu, Houxiang; Zhou, Daniel Cui; Jayasinghe, Reyka G.; Mendez, Daniel; Wendl, Michael C.; Clark, David; Newton, Chelsea; Ruan, Yijun; Reimers, Melissa A.; Pachynski, Russell K.; Kinsinger, Chris; Jewell, Scott; Chan, Daniel W.; Zhang, Hui; Chaudhuri, Aadel A.; Chheda, Milan G.; Humphreys, Benjamin D.; Mesri, Mehdi; Rodriguez, Henry; Hsieh, James J.; Ding, Li; Chen, Feng 分享 收藏
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SETD2 regulates chromatin accessibility and transcription to suppress lung tumorigenesis Xie, Yuchen; Sahin, Merve; Wakamatsu, Toru; Inoue-Yamauchi, Akane; Zhao, Wanming; Han, Song; Nargund, Amrita M.; Yang, Shaoyuan; Lyu, Yang; Hsieh, James J.; Leslie, Christina S.; Cheng, Emily H. 分享 收藏
Tumor-associated macrophages expressing the transcription factor IRF8 promote T cell exhaustion in cancer Nixon, Briana G.; Kuo, Fengshen; Ji, LiangLiang; Liu, Ming; Capistrano, Kristelle; Do, Mytrang; Franklin, Ruth A.; Wu, Xiaodi; Kansler, Emily R.; Srivastava, Raghvendra M.; Purohit, Tanaya A.; Sanchez, Alejandro; Vuong, Lynda; Krishna, Chirag; Wang, Xinxin; Morse, Herbert C., III; Hsieh, James J.; Chan, Timothy A.; Murphy, Kenneth M.; Moon, James J.; Hakimi, A. Ari; Li, Ming O. 分享 收藏
Article Multiregional single-cell proteogenomic analysis of ccRCC reveals cytokine drivers of intratumor spatial heterogeneity Miheecheva, Natalia; Postovalova, Ekaterina; Lyu, Yang; Ramachandran, Akshaya; Bagaev, Alexander; Svekolkin, Viktor; Galkin, Ilia; Zyrin, Vladimir; Maximov, Vladislav; Lozinsky, Yaroslav; Isaev, Sergey; Ovcharov, Pavel; Shamsutdinova, Diana; Cheng, Emily H.; Nomie, Krystle; Brown, Jessica H.; Tsiper, Maria; Ataullakhanov, Ravshan; Fowler, Nathan; Hsieh, James J. 分享 收藏
SETD2 loss perturbs the kidney cancer epigenetic landscape to promote metastasis and engenders actionable dependencies on histone chaperone complexes Xie, Yuchen; Sahin, Merve; Sinha, Sonali; Wang, Yufeng; Nargund, Amrita M.; Lyu, Yang; Han, Song; Dong, Yiyu; Hsieh, James J.; Leslie, Christina S.; Cheng, Emily H. 分享 收藏
First-line nivolumab plus cabozantinib vs sunitinib in patients (pts) with advanced renal cell carcinoma (aRCC) in subgroups based on prior nephrectomy in the CheckMate 9ER trial Porta, C. G.; Burotto, M.; Suarez Rodriguez, C.; Bourlon, M. T.; Hsieh, J.; Shah, A. Y.; Hamzaj, A.; Bedke, J.; Pook, D.; Kessler, R.; Tomita, Y.; Drakaki, A.; Zhang, J.; Simsek, B.; Schwab, G.; Escudier, B.; Motzer, R. J.; Choueiri, T. K.; Apolo, A. B.; Powles, T. B. 分享 收藏
A Single-arm, Multicenter, Phase 2 Study of Lenvatinib Plus Everolimus in Patients with Advanced Non-Clear Cell Renal Cell Carcinoma Lenvatinib联合依维莫司在晚期非透明细胞肾细胞癌患者中的单臂，多中心，2期研究 Hutson, Thomas E.; Michaelson, M. Dror; Kuzel, Timothy M.; Agarwal, Neeraj; Molina, Ana M.; Hsieh, James J.; Vaishampayan, Ulka N.; Xie, Ran; Bapat, Urmi; Ye, Weifei; Jain, Rohit K.; Fishman, Mayer N. 分享 收藏
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Nivolumab plus Cabozantinib versus Sunitinib for Advanced Renal-Cell Carcinoma Choueiri, T. K.; Powles, T.; Burotto, M.; Escudier, B.; Bourlon, M. T.; Zurawski, B.; Juarez, V. M. Oyervides; Hsieh, J. J.; Basso, U.; Shah, A. Y.; Suarez, C.; Hamzaj, A.; Goh, J. C.; Barrios, C.; Richardet, M.; Porta, C.; Kowalyszyn, R.; Feregrino, J. P.; Zolnierek, J.; Pook, D.; Kessler, E. R.; Tomita, Y.; Mizuno, R.; Bedke, J.; Zhang, J.; Maurer, M. A.; Simsek, B.; Ejzykowicz, F.; Schwab, G. M.; Apolo, A. B.; Motzer, R. J. 分享 收藏
Phase II trial of lenvatinib (LEN) plus pembrolizumab (PEMBRO) for progressive disease after PD-1/PD-L1 immune checkpoint inhibitor (ICI) in metastatic clear cell (mcc) renal cell carcinoma (RCC): Results by independent imaging review and subgroup analyses Lee, C-H.; Shah, A. Y.; Hsieh, J. J.; Rao, A.; Pinto, A.; Bilen, M. A.; Cohn, A. L.; Di Simone, C.; Shaffer, D. R.; Girones Sarrio, R.; Ribe, S. Gunnestad; Wu, J.; Schmidt, E.; Kubiak, P.; Okpara, C. E.; Smith, A. D.; Motzer, R. J. 分享 收藏
Nivolumab plus cabozantinib vs sunitinib in first-line treatment for advanced renal cell carcinoma: First results from the randomized phase III CheckMate 9ER trial Choueiri, T. K.; Powles, T.; Burotto, M.; Bourlon, M. T.; Zurawski, B.; Oyervides Juarez, V. M.; Hsieh, J. J.; Basso, U.; Shah, A. Y.; Suarez, C.; Hamzaj, A.; Barrios, C. H.; Richardet, M.; Pook, D.; Tomita, Y.; Escudier, B.; Zhang, J.; Simsek, B.; Apolo, A. B.; Motzer, R. J. 分享 收藏
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