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收藏TFEB triggers a matrix degradation and invasion program in triple-negative breast cancer cells upon mTORC1 repressionTFEB在mTORC1受抑制时,触发了三阴性乳腺癌细胞的基质降解和侵袭程序。
Remy, David; Antoine-Bally, Sandra; de Toqueville, Sophie; Jolly, Celia; Mace, Anne-Sophie; Champenois, Gabriel; Nemati, Fariba; Brito, Isabel; Raynal, Virginie; Priya, Amulya; Berlioz, Adele; Dahmani, Ahmed; Nicolas, Andre; Meseure, Didier; Marangoni, Elisabetta; Chavrier, Philippe
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收藏A mechanosensitive caveolae-invadosome interplay drives matrix remodelling for cancer cell invasion
Monteiro, Pedro; Remy, David; Lemerle, Eline; Routet, Fiona; Mace, Anne-Sophie; Guedj, Chloe; Ladoux, Benoit; Vassilopoulos, Stephane; Lamaze, Christophe; Chavrier, Philippe
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收藏Codependencies of mTORC1 signaling and endolysosomal actin structures
Priya, Amulya; Antoine-Bally, Sandra; Mace, Anne-Sophie; Monteiro, Pedro; Sabatet, Valentin; Remy, David; Dingli, Florent; Loew, Damarys; Demetriades, Constantinos; Gautreau, Alexis M.; Chavrier, Philippe
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收藏Force tuning through regulation of clathrin-dependent integrin endocytosis
Kyumurkov, Alexander; Bouin, Anne-Pascale; Boissan, Mathieu; Manet, Sandra; Baschieri, Francesco; Proponnet-Guerault, Mathilde; Balland, Martial; Destaing, Olivier; Regent-Kloeckner, Myriam; Calmel, Claire; Nicolas, Alice; Waharte, Francois; Chavrier, Philippe; Montagnac, Guillaume; Planus, Emmanuelle; Albiges-Rizo, Corinne
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收藏mTOR Repression in Response to Amino Acid Starvation Promotes ECM Degradation Through MT1-MMP Endocytosis Arrest
Colombero, Cecilia; Remy, David; Antoine-Bally, Sandra; Mace, Anne-Sophie; Monteiro, Pedro; ElKhatib, Nadia; Fournier, Margot; Dahmani, Ahmed; Montaudon, Elodie; Montagnac, Guillaume; Marangoni, Elisabetta; Chavrier, Philippe
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收藏Metastasis-suppressor NME1 controls the invasive switch of breast cancer by regulating MT1-MMP surface clearance
Lodillinsky, Catalina; Fuhrmann, Laetitia; Irondelle, Marie; Pylypenko, Olena; Li, Xiao-Yan; Bonsang-Kitzis, Helene; Reyal, Fabien; Vacher, Sophie; Calmel, Claire; De Wever, Olivier; Bieche, Ivan; Lacombe, Marie-Lise; Eijan, Ana Maria; Houdusse, Anne; Vincent-Salomon, Anne; Weiss, Stephen J.; Chavrier, Philippe; Boissan, Mathieu
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收藏Intersection of TKS5 and FGD1/CDC42 signaling cascades directs the formation of invadopodia
Zagryazhskaya-Masson, Anna; Monteiro, Pedro; Mace, Anne-Sophie; Castagnino, Alessia; Ferrari, Robin; Infante, Elvira; Duperray-Susini, Aleria; Dingli, Florent; Lanyi, Arpad; Loew, Damarys; Genot, Elisabeth; Chavrier, Philippe
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收藏MT1-MMP targeting to endolysosomes is mediated by upregulation of flotillins
Planchon, Damien; Morris, Eduardo Rios; Genest, Mallory; Comunale, Franck; Vacher, Sophie; Bieche, Ivan; Denisov, Evgeny V.; Tashireva, Lubov A.; Perelmuter, Vladimir M.; Linder, Stefan; Chavrier, Philippe; Bodin, Stephane; Gauthier-Rouviere, Cecile
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收藏Coronin 1C promotes triple-negative breast cancer invasiveness through regulation of MT1-MMP traffic and invadopodia function
Castagnino, Alessia; Castro-Castro, Antonio; Irondelle, Marie; Guichard, Alan; Lodillinsky, Catalina; Fuhrmann, Laetitia; Vacher, Sophie; Aguera-Gonzalez, Sonia; Zagryazhskaya-Masson, Anna; Romao, Maryse; El Kesrouani, Carole; Noegel, Angelika A.; Dubois, Thierry; Raposo, Graca; Bear, James E.; Clemen, Christoph S.; Vincent-Salomon, Anne; Bieche, Ivan; Chavrier, Philippe
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收藏A NUMB-EFA6B-ARF6 recycling route controls apically restricted cell protrusions and mesenchymal motility
Zobel, Martina; Disanza, Andrea; Senic-Matuglia, Francesca; Franco, Michel; Colaluca, Ivan Nicola; Confalonieri, Stefano; Bisi, Sara; Barbieri, Elisa; Caldieri, Giusi; Sigismund, Sara; Pece, Salvatore; Chavrier, Philippe; Di Fiore, Pier Paolo; Scita, Giorgio
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收藏LINC complex-Lisl interplay controls MT1-MMP matrix digest-on-demand response for confined tumor cell migration
Infante, Elvira; Castagnino, Alessia; Ferrari, Robin; Monteiro, Pedro; Aguera-Gonzalez, Sonia; Paul-Gilloteaux, Perrine; Domingues, Melanie J.; Maiuri, Paolo; Raab, Matthew; Shanahan, Catherine M.; Baffet, Alexandre; Piel, Matthieu; Gomes, Edgar R.; Chavrier, Philippe
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