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Thrombopoietin mimetic stimulates bone marrow vascular and stromal niches to mitigate acute radiation syndrome Vercellino, Justin; Malachowska, Beata; Kulkarni, Shilpa; Bell, Brett I.; Shajahan, Shahin; Shinoda, Kosaku; Eichenbaum, Gary; Verma, Amit K.; Ghosh, Sanchita P.; Yang, Weng-Lang; Frenette, Paul S.; Guha, Chandan 分享 收藏
Tissue-resident glial cells associate with tumoral vasculature and promote cancer progression Rocha, Beatriz G. S.; Picoli, Caroline C.; Goncalves, Bryan O. P.; Silva, Walison N.; Costa, Alinne C.; Moraes, Michele M.; Costa, Pedro A. C.; Santos, Gabryella S. P.; Almeida, Milla R.; Silva, Luciana M.; Singh, Youvika; Falchetti, Marcelo; Guardia, Gabriela D. A.; Guimaraes, Pedro P. G.; Russo, Remo C.; Resende, Rodrigo R.; Pinto, Mauro C. X.; Amorim, Jaime H.; Azevedo, Vasco A. C.; Kanashiro, Alexandre; Nakaya, Helder I.; Rocha, Edroaldo L.; Galante, Pedro A. F.; Mintz, Akiva; Frenette, Paul S.; Birbrair, Alexander 分享 收藏
Inflammatory exposure drives long-lived impairment of hematopoietic stem cell self-renewal activity and accelerated aging 炎症暴露导致造血干细胞自我更新活动的长期损害和加速衰老 Bogeska, Ruzhica; Mikecin, Ana-Matea; Kaschutnig, Paul; Fawaz, Malak; Buechler-Schaeff, Marleen; Le, Duy; Ganuza, Miguel; Vollmer, Angelika; Paffenholz, Stella, V; Asada, Noboru; Rodriguez-Correa, Esther; Frauhammer, Felix; Buettner, Florian; Ball, Melanie; Knoch, Julia; Staeble, Sina; Walter, Dagmar; Petri, Amelie; Carreno-Gonzalez, Martha J.; Wagner, Vinona; Brors, Benedikt; Haas, Simon; Lipka, Daniel B.; Essers, Marieke A. G.; Weru, Vivienn; Holland-Letz, Tim; Mallm, Jan-Philipp; Rippe, Karsten; Kraemer, Stephan; Schlesner, Matthias; Freeman, Shannon McKinney; Florian, Maria Carolina; King, Katherine Y.; Frenette, Paul S.; Rieger, Michael A.; Milsom, Michael D. 分享 收藏
Tet-mediated DNA demethylation regulates specification of hematopoietic stem and progenitor cells during mammalian embryogenesis Ma, Liyang; Tang, Qin; Gao, Xin; Lee, Joun; Lei, Run; Suzuki, Masako; Zheng, Deyou; Ito, Keisuke; Frenette, Paul S.; Dawlaty, Meelad M. 分享 收藏
VCAM1 confers innate immune tolerance on haematopoietic and leukaemic stem cells Pinho, Sandra; Wei, Qiaozhi; Maryanovich, Maria; Zhang, Dachuan; Balandran, Juan Carlos; Pierce, Halley; Nakahara, Fumio; Di Staulo, Anna; Bartholdy, Boris A.; Xus, Jianing; Borger, Daniel K.; Verma, Amit; Frenette, Paul S. 分享 收藏
Olinciguat, a stimulator of soluble guanylyl cyclase, attenuates inflammation, vaso-occlusion and nephropathy in mouse models of sickle cell disease Tchernychev, Boris; Li, Huihui; Lee, Sung-Kyun; Gao, Xin; Ramanarasimhaiah, Raghunath; Liu, Guang; Hall, Katherine C.; Bernier, Sylvie G.; Jones, Juli E.; Feil, Susanne; Feil, Robert; Buys, Emmanuel S.; Graul, Regina M.; Frenette, Paul S.; Masferrer, Jaime L. 分享 收藏
MAEA is an E3 ubiquitin ligase promoting autophagy and maintenance of haematopoietic stem cells Wei, Qiaozhi; Pinho, Sandra; Dong, Shuxian; Pierce, Halley; Li, Huihui; Nakahara, Fumio; Xu, Jianing; Xu, Chunliang; Boulais, Philip E.; Zhang, Dachuan; Maryanovich, Maria; Cuervo, Ana Maria; Frenette, Paul S. 分享 收藏
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Bone marrow NG2+/Nestin+ mesenchymal stem cells drive DTC dormancy via TGF-β2 骨髓NG2 /Nestin间充质干细胞通过TGF-β2驱动DTC休眠 Nobre, Ana Rita; Risson, Emma; Singh, Deepak K.; Di Martino, Julie S.; Cheung, Julie F.; Wang, Jiapeng; Johnson, John; Russnes, Hege G.; Bravo-Cordero, Jose Javier; Birbrair, Alexander; Naume, Bjorn; Azhar, Mohamad; Frenette, Paul S.; Aguirre-Ghiso, Julio A. 分享 收藏
Niche derived netrin-1 regulates hematopoietic stem cell dormancy via its receptor neogenin-1 Renders, Simon; Svendsen, Arthur Flohr; Panten, Jasper; Rama, Nicolas; Maryanovich, Maria; Sommerkamp, Pia; Ladel, Luisa; Redavid, Anna Rita; Gibert, Benjamin; Lazare, Seka; Ducarouge, Benjamin; Schoenberger, Katharina; Narr, Andreas; Tourbez, Manon; Dethmers-Ausema, Bertien; Zwart, Erik; Hotz-Wagenblatt, Agnes; Zhang, Dachuan; Korn, Claudia; Zeisberger, Petra; Przybylla, Adriana; Sohn, Markus; Mendez-Ferrer, Simon; Heikenwaelder, Mathias; Brune, Maik; Klimmeck, Daniel; Bystrykh, Leonid; Frenette, Paul S.; Mehlen, Patrick; de Haan, Gerald; Cabezas-Wallscheid, Nina; Trumpp, Andreas 分享 收藏
Future directions in preclinical and translational cancer neuroscience research Demir, Ihsan Ekin; Reyes, Carmen Mota; Alrawashdeh, Wasfi; Ceyhan, Gueralp O.; Deborde, Sylvie; Friess, Helmut; Goerguelue, Kivanc; Istvanffy, Rouzanna; Jungwirth, David; Kuner, Rohini; Maryanovich, Maria; Na'ara, Shorook; Renders, Simon; Saloman, Jami L.; Scheff, Nicole N.; Steenfadt, Hendrik; Stupakov, Pavel; Thiel, Vera; Verma, Divij; Yilmaz, Bengi Su; White, Ruth A.; Wang, Timothy C.; Wong, Richard J.; Frenette, Paul S.; Gil, Ziv; Davis, Brian M. 分享 收藏
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Very low incidence of Clostridioides difficile infection in pediatric sickle cell disease patients Lee, Philip; Sinha, Arpan A.; Soma, Vijaya L.; Cruz, Carlos; Wang, Tao; Aroniadis, Olga; Herold, Betsy C.; Frenette, Paul S.; Goldman, David L.; Manwani, Deepa 分享 收藏
Beneficial Effects of Soluble Guanylyl Cyclase Stimulation and Activation in Sickle Cell Disease Are Amplified by Hydroxyurea: In Vitro and In Vivo Studies Ferreira, W. A., Jr.; Chweih, H.; Lanaro, C.; Almeida, C. B.; Brito, P. L.; Gotardo, E. M. F.; Torres, L.; Miguel, L., I; Franco-Penteado, C. F.; Leonardo, F. C.; Garcia, F.; Saad, S. T. O.; Frenette, P. S.; Brockschnieder, D.; Costa, F. F.; Stasch, J. P.; Sandner, P.; Conran, N. 分享 收藏
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Randomized phase 2 trial of Intravenous Gamma Globulin (IVIG) for the treatment of acute vaso-occlusive crisis in patients with sickle cell disease: Lessons learned from the midpoint analysis Manwani, Deepa; Xu, Chunliang; Lee, Sung Kyun; Amatuni, George; Cohen, Hillel W.; Carullo, Veronica; Morrone, Kerry; Davila, Jennifer; Shi, Patricia Ann; Ireland, Karen; Keenan, Janine; Frenette, Paul S. 分享 收藏
Snai2 Maintains Bone Marrow Niche Cells by Repressing Osteopontin Expression Wei, Qiaozhi; Nakahara, Fumio; Asada, Noboru; Zhang, Dachuan; Gao, Xin; Xu, Chunliang; Alfieri, Alan; Brodin, N. Patrik; Zimmerman, Samuel E.; Mar, Jessica C.; Guha, Chandan; Guo, Wenjun; Frenette, Paul S. 分享 收藏
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