未登录An integrated approach identifies the molecular underpinnings of murine anterior visceral endoderm migration
Thowfeequ, Shifaan; Fiorentino, Jonathan; Hu, Di; Solovey, Maria; Ruane, Sharon; Whitehead, Maria; Zhou, Felix; Godwin, Jonathan; Mateo-Otero, Yentel; Vanhaesebroeck, Bart; Scialdone, Antonio; Srinivas, Shankar
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收藏ASPP2 maintains the integrity of mechanically stressed pseudostratified epithelia during morphogenesisASPP2在形态发生过程中维持机械应力假复层上皮的完整性
Royer, Christophe; Sandham, Elizabeth; Slee, Elizabeth; Schneider, Falk; Lagerholm, Christoffer B.; Godwin, Jonathan; Veits, Nisha; Hathrell, Holly; Zhou, Felix; Leonavicius, Karolis; Garratt, Jemma; Narendra, Tanaya; Vincent, Anna; Jones, Celine; Child, Tim; Coward, Kevin; Graham, Chris; Fritzsche, Marco; Lu, Xin; Srinivas, Shankar
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收藏The non-canonical SMC protein SmcHD1 antagonises TAD formation and compartmentalisation on the inactive X chromosome
Gdula, Michal R.; Nesterova, Tatyana B.; Pintacuda, Greta; Godwin, Jonathan; Zhan, Ye; Ozadam, Hakan; McClellan, Michael; Moralli, Daniella; Krueger, Felix; Green, Catherine M.; Reik, Wolf; Kriaucionis, Skirmantas; Heard, Edith; Dekker, Job; Brockdorff, Neil
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收藏PLCζ is the physiological trigger of the Ca2+ oscillations that induce embryogenesis in mammals but conception can occur in its absence
Hachem, Alaa; Godwin, Jonathan; Ruas, Margarida; Lee, Hoi Chang; Buitrago, Minerva Ferrer; Ardestani, Goli; Bassett, Andrew; Fox, Sebastian; Navarrete, Felipe; de Sutter, Petra; Heindryckx, Bjorn; Fissore, Rafael; Parrington, John
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收藏APC/CCdh1 Enables Removal of Shugoshin-2 from the Arms of Bivalent Chromosomes by Moderating Cyclin-Dependent Kinase Activity
Rattani, Ahmed; Mejia, Randy Ballesteros; Roberts, Katherine; Roig, Maurici B.; Godwin, Jonathan; Hopkins, Michael; Eguren, Manuel; Sanchez-Pulido, Luis; Okaz, Elwy; Ogushi, Sugako; Wolna, Magda; Metson, Jean; Pendas, Alberto M.; Malumbres, Marcos; Novak, Bela; Herbert, Mary; Nasmyth, Kim
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收藏APC/CCdh1 maintains primordial follicles, germinal vesicle arrest and ensures balanced segregation of chromosomes by enabling removal of Shugoshin-2 from chromosomes arms
Rattani, Ahmed; Mejia, Randy Ballestros; Roberts, Katherine; Roig, Maurici B.; Godwin, Jonathan; Eguren, Manuel; Ogushi, Sugako; Okaz, Elwy; Pendas, Alberto; Marcos, Malumbres; Herbert, Mary; Nasmyth, Kim
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收藏Functional analysis of AEBP2, a PRC2 Polycomb protein, reveals a Trithorax phenotype in embryonic development and in ESCs
Grijzenhout, Anne; Godwin, Jonathan; Koseki, Haruhiko; Gdula, Michal Ryszard; Szumska, Dorota; McGouran, Joanna F.; Bhattacharya, Shoumo; Kessler, Benedikt M.; Brockdorff, Neil; Cooper, Sarah
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收藏Sgol2 provides a regulatory platform that coordinates essential cell cycle processes during meiosis I in oocytesSgol2提供了一个调控平台,可协调卵母细胞减数分裂I期间的基本细胞周期过程
Rattani, Ahmed; Wolna, Magda; Ploquin, Mickael; Helmhart, Wolfgang; Morrone, Seamus; Mayer, Bernd; Godwin, Jonathan; Xu, Wenqing; Stemmann, Olaf; Pendas, Alberto; Nasmyth, Kim
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收藏Smchd1-Dependent and -Independent Pathways Determine Developmental Dynamics of CpG Island Methylation on the Inactive X Chromosome
Gendrel, Anne-Valerie; Apedaile, Anwyn; Coker, Heather; Termanis, Ausma; Zvetkova, Ilona; Godwin, Jonathan; Tang, Y. Amy; Huntley, Derek; Montana, Giovanni; Taylor, Steven; Giannoulatou, Eleni; Heard, Edith; Stancheva, Irina; Brockdorff, Neil
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收藏Targeting the CXCR4-CXCL12 Axis Mobilizes Autologous Hematopoietic Stem Cells and Prolongs Islet Allograft Survival via Programmed Death Ligand 1
Fiorina, Paolo; Jurewicz, Mollie; Vergani, Andrea; Petrelli, Alessandra; Carvello, Michele; D'Addio, Francesca; Godwin, Jonathan G.; Law, Kenneth; Wu, Erxi; Tian, Ze; Thoma, Gebhard; Kovarik, Jiri; La Rosa, Stefano; Capella, Carlo; Rodig, Scott; Zerwes, Hans-Guenter; Sayegh, Mohamed H.; Abdi, Reza
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收藏Congenic Mesenchymal Stem Cell Therapy Reverses Hyperglycemia in Experimental Type 1 Diabetes
Jurewicz, Mollie; Yang, Sunmi; Augello, Andrea; Godwin, Jonathan G.; Moore, Robert F.; Azzi, Jamil; Fiorina, Paolo; Atkinson, Mark; Sayegh, Mohamed H.; Abdi, Reza
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