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Sarcomas developed in patients with Lynch Syndrome are enriched in pleomorphic soft-tissue sarcomas and are sensitive to immunotherapy 林奇综合征患者中发生的肉瘤富集于多形性软组织肉瘤，并且对免疫疗法敏感。 Poumeaud, F.; Valentin, T.; Fares, N.; Segier, B.; Watson, S.; Verret, B.; Tlemsani, C.; Penel, N.; Lejeune, S.; Firmin, N.; Sabouret, A.; Thery, J. -C; Bonvalot, S.; Cottereau, E.; Cauchin, E.; Lancon, A.; Nambot, S.; Zattara, H.; Coudert, M.; Fourme, E.; Nogues, C.; Tougeron, D.; Prieur, F.; Collonge-Rame, M. -A; Denis, C.; Laurent-Puig, P.; Chieze-Valero, S.; Dreyfus, H.; Jaffrelot, M.; Vande Perre, P.; Rochaix, P.; Gomez-Mascard, A.; Rochefort, P.; Campoy, S.; Chibon, F.; Lasset, C.; Selves, J.; Guimbaud, R. 分享 收藏
A metabolic crosstalk between liposarcoma and muscle sustains tumor growth Manteaux, Gabrielle; Amsel, Alix; Riquier-Morcant, Blanche; Prieto Romero, Jaime; Gayte, Laurie; Fourneaux, Benjamin; Larroque, Marion; Gruel, Nadege; Quignot, Chloe; Perot, Gaelle; Jacq, Solenn; Cisse, Madi Y.; Pomies, Pascal; Sengenes, Coralie; Chibon, Frederic; Heuillet, Maud; Bellvert, Floriant; Watson, Sarah; Carrere, Sebastien; Firmin, Nelly; Riscal, Romain; Linares, Laetitia K. 分享 收藏
Genomic profile analysis of leiomyomas with bizarre nuclei and fumarate hydratase deficient leiomyomas: Strengths, weaknesses, and limitations of array-CGH interpretation 具有奇异核的平滑肌瘤和富马酸水合酶缺陷型平滑肌瘤的基因组图谱分析: array-cgh解释的优势，劣势和局限性 Fontanges, Quitterie; Dubos, Paul; Lesluyes, Tom; Laizet, Yec'han; Velasco, Valerie; Melendez, Barbara; D'Haene, Nicky; Oliva, Esther; Young, Robert H.; Mayeur, Laetitia; Rebier, Flora; Alame, Melissa; Larmonier, Claire; Devouassoux-Shisheboran, Mojgan; Arnould, Laurent; Soubeyran, Isabelle; Chakiba, Camille; Floquet, Anne; Babin, Guillaume; Guyon, Frederic; Mery, Eliane; Le Guellec, Sophie; Noel, Jean-Christophe; Croce, Sabrina; Chibon, Frederic 分享 收藏
Special features of sarcomas developed in patients with Lynch syndrome: A systematic review Poumeaud, Francois; Valentin, Thibaud; Vande Perre, Pierre; Jaffrelot, Marion; Bonnet, Delphine; Chibon, Frederic; Chevreau, Christine; Selves, Janick; Guimbaud, Rosine; Fares, Nadim 分享 收藏
The hereditary N363K POLE exonuclease mutant extends PPAP tumor spectrum to glioblastomas by causing DNA damage and aneuploidy in addition to increased mismatch mutagenicity Labrousse, Guillaume; Vande Perre, Pierre; Parra, Genis; Jaffrelot, Marion; Leroy, Laura; Chibon, Frederic; Escudie, Frederic; Selves, Janick; Hoffmann, Jean-Sebastien; Guimbaud, Rosine; Lutzmann, Malik 分享 收藏
CINSARC signature outperforms gold-standard TNM staging and consensus molecular subtypes for clinical outcome in stage II-III colorectal carcinoma Brunac, Anne-Cecile; Fourquet, Joanna; Perot, Gaelle; Jaffrelot, Marion; Meilleroux, Julie; Danjoux, Marie; Filleron, Thomas; Nicolai, Vincent; Guimbaud, Rosine; Icher, Samira; Fares, Nadim; Selves, Janick; Chibon, Frederic 分享 收藏
Medium levels of transcription and replication related chromosomal instability are associated with poor clinical outcome Benhaddou, Ataaillah; Gaston, Laetitia; Perot, Gaelle; Desplat, Nelly; Leroy, Laura; Le Guellec, Sophie; Ben Haddou, Mohamed; Rochaix, Philippe; Valentin, Thibaud; Ferron, Gwenael; Chevreau, Christine; Bui, Binh; Stoeckle, Eberhard; Le Cesne, Axel; Piperno-Neumann, Sophie; Collin, Francoise; Firmin, Nelly; De Pinieux, Gonzague; Coindre, Jean-Michel; Blay, Jean-Yves; Chibon, Frederic 分享 收藏
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Relationships between highly recurrent tumor suppressor alterations in 489 leiomyosarcomas Schaefer, Inga-Marie; Lundberg, Meijun Z.; Demicco, Elizabeth G.; Przybyl, Joanna; Matusiak, Magdalena; Chibon, Frederic; Ingram, Davis R.; Hornick, Jason L.; Wang, Wei-Lien; Bauer, Sebastian; Baker, Laurence H.; Lazar, Alexander J.; van de Rijn, Matt; Marino-Enriquez, Adrian; Fletcher, Jonathan A. 分享 收藏
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Expression and prognostic significance of PDGF ligands and receptors across soft tissue sarcomas Brahmi, M.; Lesluyes, T.; Dufresne, A.; Toulmonde, M.; Italiano, A.; Mir, O.; Le Cesne, A.; Valentin, T.; Chevreau, C.; Bonvalot, S.; Penel, N.; Coindre, J-M; Le Guellec, S.; Le Loarer, F.; Karanian, M.; Blay, J-Y; Chibon, F. 分享 收藏
Cell-cell fusion of mesenchymal cells with distinct differentiations triggers genomic and transcriptomic remodelling toward tumour aggressiveness Delespaul, Lucile; Gelabert, Caroline; Lesluyes, Tom; Le Guellec, Sophie; Perot, Gaelle; Leroy, Laura; Baud, Jessica; Merle, Candice; Lartigue, Lydia; Chibon, Frederic 分享 收藏
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Value of peri-operative chemotherapy in patients with CINSARC high-risk localized grade 1 or 2 soft tissue sarcoma: study protocol of the target selection phase III CHIC-STS trial Filleron, Thomas; Le Guellec, Sophie; Chevreau, Christine; Cabarrou, Bastien; Lesluyes, Tom; Lodin, Sabrina; Massoubre, Angelique; Mounier, Muriel; Poublanc, Muriel; Chibon, Frederic; Valentin, Thibaud 分享 收藏
Specific immune landscapes and immune checkpoint expressions in histotypes and molecular subtypes of sarcoma Dufresne, A.; Lesluyes, T.; Menetrier-Caux, C.; Brahmi, M.; Darbo, E.; Toulmonde, M.; Italiano, A.; Mir, O.; Le Cesne, A.; Le Guellec, S.; Valentin, T.; Chevreau, C.; Bonvalot, S.; Robin, Y. M.; Coindre, J-M; Caux, C.; Blay, J. Y.; Chibon, F. 分享 收藏
Targeting MDM2-dependent serine metabolism as a therapeutic strategy for liposarcoma Cisse, Madi Y.; Pyrdziak, Samuel; Firmin, Nelly; Gayte, Laurie; Heuillet, Maud; Bellvert, Floriant; Fuentes, Maryse; Delpech, Helene; Riscal, Romain; Arena, Giuseppe; Chibon, Frederic; Le Gellec, Sophie; Maran-Gonzalez, Aurelie; Chateau, Marie-Christine; Theillet, Charles; Carrere, Sebastien; Portais, Jean-Charles; Le Cam, Laurent; Linares, Laetitia K. 分享 收藏
Genome remodeling upon mesenchymal tumor cell fusion contributes to tumor progression and metastatic spread Lartigue, Lydia; Merle, Candice; Lagarde, Pauline; Delespaul, Lucile; Lesluyes, Tom; Le Guellec, Sophie; Perot, Gaelle; Leroy, Laura; Coindre, Jean-Michel; Chibon, Frederic 分享 收藏
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