未登录Population Pharmacokinetic Modelling of Remdesivir and Its Metabolite GS-441524 in Hospitalised Patients with COVID-19瑞德西韦及其代谢物GS-441524在住院COVID-19患者中的群体药代动力学模型构建
Roberts, Darren M.; Liu, Xin; Parker, Suzanne L.; Burke, Andrew; Peek, Jenny; Carland, Jane E.; Murnion, Bridin; Seah, Vincent; Wallis, Steven C.; Sumi, Chandra D.; Pandey, Saurabh; Buscher, Hergen; Byrne, Anthony; Sandaradura, Indy; Bowen, David; Holz, Simon; Stewart, Adam G.; Hajkowicz, Krispin M.; Roberts, Jason A. .png)
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收藏RUX-AZA Response in AP/BP-MPN Is Driven By Release of the Differentiation Block in Mutant HSPCs: A Single-Cell Multi-Omic Analysis of Responders on the Phase Ib Phazar StudyRUX-AZA对AP/BP-MPN的响应由突变HSPCs的分化阻滞释放驱动：一项对Phazar Ib期研究中响应者的单细胞多组学分析Brierley, Charlotte K.; Gaskell, Charlotte; Harrison, Claire; Yap, Christina; Jackson, Aimee; Byrne, Jennifer; Hamblin, Angela; Clark, Sally-Ann; Sullivan, Jennifer O.; Rodriguez-Meira, Alba; Murphy, Lauren; Clarke, Fiona Jane; Narayanan, Srinivasan; Bowen, David T.; Gudgin, Emma; Milojkovic, Dragana; Collings, Rebecca; Psaila, Bethan; Knapper, Steve; Drummond, Mark W.; Mead, Adam J. 分享 收藏 Red cell transfusion thresholds in outpatients with myelodysplastic syndromes: Combined results from two randomized controlled feasibility studiesBuckstein, Rena; Callum, Jeannie; Prica, Anca; Bowen, David; Wells, Richard A.; Leber, Brian; Heddle, Nancy; Chodirker, Lisa; Cheung, Matthew; Mozessohn, Lee; Yee, Karen; Gallagher, Jennifer; Parmentier, Anne; Jamula, Erin; McQuilten, Zoe; Wood, Erica M.; Weinkov, Robert; Zhang, Liying; Mamedov, Alex; Stanworth, Simon J.; Lin, Yulia 分享 收藏 Determinants of low health-related quality of life in patients with myelodysplastic syndromes: EUMDS Registry studyStojkov, Igor; Conrads-Frank, Annette; Rochau, Ursula; Arvandi, Marjan; Koinig, Karin A.; Schomaker, Michael; Mittelman, Moshe; Fenaux, Pierre; Bowen, David; Sanz, Guillermo F.; Malcovati, Luca; Langemeijer, Saskia; Germing, Ulrich; Madry, Krzysztof; Guerci-Bresler, Agnes; Culligan, Dominic J.; Kotsianidis, Ioannis; Sanhes, Laurence; Mills, Juliet; Puntscher, Sibylle; Schmid, Daniela; van Marrewijk, Corine; Smith, Alexandra; Efficace, Fabio; de Witte, Theo; Stauder, Reinhard; Siebert, Uwe 分享 收藏 Core set of patient-reported outcomes for myelodysplastic syndromes: an EUMDS Delphi study involving patients and hematologists骨髓增生异常综合征患者报告的核心结局集: 一项涉及患者和血液学家的EUMDS Delphi研究Stojkov, Igor; Conrads-Frank, Annette; Rochau, Ursula; Koinig, Karin A.; Arvandi, Marjan; Puntscher, Sibylle; van Marrewijk, Corine; Fenaux, Pierre; Symeonidis, Argiris; Chermat, Fatiha; Garelius, Hege; Bowen, David; Mittelman, Moshe; Mora, Elvira; de Witte, Theo; Efficace, Fabio; Siebert, Uwe; Stauder, Reinhard 分享 收藏 A predictive algorithm using clinical and laboratory parameters may assist in ruling out and in diagnosing MDSOster, Howard S.; Crouch, Simon; Smith, Alexandra; Yu, Ge; Abu Shrkihe, Bander; Baruch, Shoham; Kolomansky, Albert; Ben-Ezra, Jonathan; Naor, Shachar; Fenaux, Pierre; Symeonidis, Argiris; Stauder, Reinhard; Cermak, Jaroslav; Sanz, Guillermo; Hellstrom-Lindberg, Eva; Malcovati, Luca; Langemeijer, Saskia; Germing, Ulrich; Holm, Mette Skov; Madry, Krzysztof; Guerci-Bresler, Agnes; Culligan, Dominic; Sanhes, Laurence; Mills, Juliet; Kotsianidis, Ioannis; van Marrewijk, Corine; Bowen, David; de Witte, Theo; Mittelman, Moshe 分享 收藏 Novel dynamic outcome indicators and clinical endpoints in myelodysplastic syndrome; the European LeukemiaNet MDS Registry and MDS-RIGHT project perspectivede Witte, Theo; Malcovati, Luca; Fenaux, Pierre; Bowen, David; Symeonidis, Argiris; Mittelman, Moshe; Stauder, Reinhard; Sanz, Guillermo; Cermak, Jaroslav; Langemeijer, Saskia; Hellstrom-Lindberg, Eva; Germing, Ulrich; Holm, Mette Skov; Madry, Krzysztof; Tatic, Aurelia; Almeida, Antonio Medina; Savic, Aleksandar; Rogulj, Inga Mandac; Itzykson, Raphael; Hoeks, Marlijn; Garelius, Hege Gravdahl; Culligan, Dominic; Kotsianidis, Ioannis; Ades, Lionel; van de Loosdrecht, Arjan A.; van Marrewijk, Corine; Yu, Ge; Crouch, Simon; Smith, Alex 分享 收藏 Toxic iron species in lower-risk myelodysplastic syndrome patients: course of disease and effects on outcomeHoeks, Marlijn; Bagguley, Tim; van Marrewijk, Corine; Smith, Alex; Bowen, David; Culligan, Dominic; Kolade, Seye; Symeonidis, Argiris; Garelius, Hege; Spanoudakis, Michail; Langemeijer, Saskia; Roelofs, Rian; Wiegerinck, Erwin; Tatic, Aurelia; Killick, Sally; Panagiotidis, Panagiotis; Stanca, Oana; Hellstrom-Lindberg, Eva; Cermak, Jaroslav; van der Klauw, Melanie; Wouters, Hanneke; van Kraaij, Marian; Blijlevens, Nicole; Swinkels, Dorine W.; de Witte, Theo 分享 收藏 Guideline-based indicators for adult patients with myelodysplastic syndromesStojkov, Kristina; Silzle, Tobias; Stussi, Georg; Schwappach, David; Bernhard, Juerg; Bowen, David; Cermak, Jaroslav; Dinmohamed, Avinash G.; Eeltink, Corien; Eggmann, Sabrina; Fenaux, Pierre; Germing, Ulrich; Haschke, Manuel; Hellstrom-Lindberg, Eva; Heger, Monika; van de Loosdrecht, Arjan A.; Passweg, Jakob; Pfeilstoecker, Michael; Platzbecker, Uwe; Malcovati, Luca; de Almeida, Antonio Medina; Mittelman, Moshe; Morgenthaler, Christine; Steensma, David P.; Santini, Valeria; Stauder, Reinhard; Symeonidis, Argiris; Schaer, Saemi; Maddox, Charlotte; de Witte, Theo; Bohlius, Julia; Bonadies, Nicolas 分享 收藏 Special considerations in the management of adult patients with acute leukaemias and myeloid neoplasms in the COVID-19 era: recommendations from a panel of international expertsZeidan, Amer M.; Boddu, Prajwal C.; Patnaik, Mrinal M.; Bewersdorf, Jan Philipp; Stahl, Maximilian; Rampal, Raajit K.; Shallis, Rory M.; Steensma, David P.; Savona, Michael R.; Sekeres, Mikkael A.; Roboz, Gail J.; DeAngelo, Daniel J.; Schuh, Andre C.; Padron, Eric; Zeidner, Joshua F.; Walter, Roland B.; Onida, Francesco; Fathi, Amir T.; DeZern, Amy; Hobbs, Gabriela; Stein, Eytan M.; Vyas, Paresh; Wei, Andrew H.; Bowen, David T.; Montesinos, Pau; Griffiths, Elizabeth A.; Verma, Amit K.; Keyzner, Alla; Bar-Natan, Michal; Navada, Shyamala C.; Kremyanskaya, Marina; Goldberg, Aaron D.; Al-Kali, Aref; Heaney, Mark L.; Nazha, Aziz; Salman, Huda; Luger, Selina; Pratz, Keith W.; Konig, Heiko; Komrokji, Rami; Deininger, Michael; Cirici, Blanca Xicoy; Bhatt, Vijaya Raj; Silverman, Lewis R.; Erba, Harry P.; Fenaux, Pierre; Platzbecker, Uwe; Santini, Valeria; Wang, Eunice S.; Tallman, Martin S.; Stone, Richard M.; Mascarenhas, John 分享 收藏 The complex genetic landscape of familial MDS and AML reveals pathogenic germline variantsRio-Machin, Ana; Vulliamy, Tom; Hug, Nele; Walne, Amanda; Tawana, Kiran; Cardoso, Shirleny; Ellison, Alicia; Pontikos, Nikolas; Wang, Jun; Tummala, Hemanth; Al Seraihi, Ahad Fahad H.; Alnajar, Jenna; Bewicke-Copley, Findlay; Armes, Hannah; Barnett, Michael; Bloor, Adrian; Bodor, Csaba; Bowen, David; Fenaux, Pierre; Green, Andrew; Hallahan, Andrew; Hjorth-Hansen, Henrik; Hossain, Upal; Killick, Sally; Lawson, Sarah; Layton, Mark; Male, Alison M.; Marsh, Judith; Mehta, Priyanka; Mous, Rogier; Nomdedeu, Josep F.; Owen, Carolyn; Pavlu, Jiri; Payne, Elspeth M.; Protheroe, Rachel E.; Preudhomme, Claude; Pujol-Moix, Nuria; Renneville, Aline; Russell, Nigel; Saggar, Anand; Sciuccati, Gabriela; Taussig, David; Toze, Cynthia L.; Uyttebroeck, Anne; Vandenberghe, Peter; Schlegelberger, Brigitte; Ripperger, Tim; Steinemann, Doris; Wu, John; Mason, Joanne; Page, Paula; Akiki, Susanna; Reay, Kim; Cavenagh, Jamie D.; Plagnol, Vincent; Caceres, Javier F.; Fitzgibbon, Jude; Dokal, Inderjeet 分享 收藏 Luspatercept in Patients with Lower-Risk Myelodysplastic SyndromesFenaux, Pierre; Platzbecker, Uwe; Mufti, Ghulam J.; Garcia-Manero, Guillermo; Buckstein, Rena; Santini, Valeria; Diez-Campelo, Maria; Finelli, Carlo; Cazzola, Mario; Ilhan, Osman; Sekeres, Mikkael A.; Falantes, Jose F.; Arrizabalaga, Beatriz; Salvi, Flavia; Giai, Valentina; Vyas, Paresh; Bowen, David; Selleslag, Dominik; DeZern, Amy E.; Jurcic, Joseph G.; Germing, Ulrich; Goetze, Katharina S.; Quesnel, Bruno; Beyne-Rauzy, Odile; Cluzeau, Thomas; Voso, Maria-Teresa; Mazure, Dominiek; Vellenga, Edo; Greenberg, Peter L.; Hellstrom-Lindberg, Eva; Zeidan, Amer M.; Ades, Lionel; Verma, Amit; Savona, Michael R.; Laadem, Abderrahmane; Benzohra, Aziz; Zhang, Jennie; Rampersad, Anita; Dunshee, Diana R.; Linde, Peter G.; Sherman, Matthew L.; Komrokji, Rami S.; List, Alan F. 分享 收藏 Impact of treatment with iron chelation therapy in patients with lower-risk myelodysplastic syndromes participating in the European MDS registryHoeks, Marlijn; Yu, Ge; Langemeijer, Saskia; Crouch, Simon; de Swart, Louise; Fenaux, Pierre; Symeonidis, Argiris; Cermak, Jaroslav; Hellstrom-Lindberg, Eva; Sanz, Guillermo; Stauder, Reinhard; Holm, Mette Skov; Mittelman, Moshe; Madry, Krzysztof; Malcovati, Luca; Tatic, Aurelia; Almeida, Antonio Medina; Germing, Ulrich; Savic, Aleksandar; Simec, Njetocka Gredelj; Culligan, Dominic; Itzykson, Raphael; Guerci-Bresler, Agnes; Slama, Borhane; van de Loosdrecht, Arjan; van Marrewijk, Corine; Droste, Jackie; Blijlevens, Nicole; van Kraaij, Marian; Bowen, David; de Witte, Theo; Smith, Alex 分享 收藏 Impact of red blood cell transfusion dose density on progression-free survival in patients with lower-risk myelodysplastic syndromesde Swart, Louise; Crouch, Simon; Hoeks, Marlijn; Smith, Alex; Langemeijer, Saskia; Fenaux, Pierre; Symeonidis, Argiris; Cermak, Jaroslav; Hellstrom-Lindberg, Eva; Stauder, Reinhard; Sanz, Guillermo; Mittelman, Moshe; Holm, Mette Skov; Malcovati, Luca; Madry, Krzysztof; Germing, Ulrich; Tatic, Aurelia; Savic, Aleksandar; Almeida, Antonio Medina; Gredelj-Simec, Njetocka; Guerci-Bresler, Agnes; Beyne-Rauzy, Odile; Culligan, Dominic; Kotsianidis, Ioannis; Itzykson, Raphael; van Marrewijk, Corine; Blijlevens, Nicole; Bowen, David; de Witte, Theo 分享 收藏 TP53 mutation status divides myelodysplastic syndromes with complex karyotypes into distinct prognostic subgroupsHaase, Detlef; Stevenson, Kristen E.; Neuberg, Donna; Maciejewski, Jaroslaw P.; Nazha, Aziz; Sekeres, Mikkael A.; Ebert, Benjamin L.; Garcia-Manero, Guillermo; Haferlach, Claudia; Haferlach, Torsten; Kern, Wolfgang; Ogawa, Seishi; Nagata, Yasunobu; Yoshida, Kenichi; Graubert, Timothy A.; Walter, Matthew J.; List, Alan F.; Komrokji, Rami S.; Padron, Eric; Sallman, David; Papaemmanuil, Elli; Campbell, Peter J.; Savona, Michael R.; Seegmiller, Adam; Ades, Lionel; Fenaux, Pierre; Shih, Lee-Yung; Bowen, David; Groves, Michael J.; Tauro, Sudhir; Fontenay, Michaela; Kosmider, Olivier; Bar-Natan, Michal; Steensma, David; Stone, Richard; Heuser, Michael; Thol, Felicitas; Cazzola, Mario; Malcovati, Luca; Karsan, Aly; Ganster, Christina; Hellstrom-Lindberg, Eva; Boultwood, Jacqueline; Pellagatti, Andrea; Santini, Valeria; Quek, Lynn; Vyas, Paresh; Tuechler, Heinz; Greenberg, Peter L.; Bejar, Rafael 分享 收藏 Early platelet count kinetics has prognostic value in lower-risk myelodysplastic syndromesItzykson, Raphael; Crouch, Simon; Travaglino, Erica; Smith, Alex; Symeonidis, Argiris; Hellstrom-Lindberg, Eva; Sanz, Guillermo; Cermak, Jaroslav; Stauder, Reinhard; Elena, Chiara; Germing, Ulrich; Mittelman, Moshe; Langemeijer, Saskia; Madry, Krzysztof; Tatic, Aurelia; Holm, Mette Skov; Almeida, Antonio Medina; Savic, Aleksander; Simec, Njetocka Gredelj; Luno, Elise; Culligan, Dominic; Guerci-Bresler, Agnes; Malcovati, Luca; van Marrewijk, Corine; Bowen, David; de Witte, Theo; Fenaux, Pierre 分享 收藏 Health-related quality of life in lower-risk MDS patients compared with age- and sex-matched reference populations: a European LeukemiaNet studyStauder, Reinhard; Yu, Ge; Koinig, Karin A.; Bagguley, Tim; Fenaux, Pierre; Symeonidis, Argiris; Sanz, Guillermo; Cermak, Jaroslav; Mittelman, Moshe; Hellstrom-Lindberg, Eva; Langemeijer, Saskia; Holm, Mette Skov; Madry, Krzysztof; Malcovati, Luca; Tatic, Aurelia; Germing, Ulrich; Savic, Aleksandar; van Marrewijk, Corine; Guerci-Bresler, Agnes; Luno, Elisa; Droste, Jackie; Efficace, Fabio; Smith, Alex; Bowen, David; de Witte, Theo 分享 收藏 Labile plasma iron levels predict survival in patients with lower-risk myelodysplastic syndromesde Swart, Louise; Reiniers, Chloe; Bagguley, Timothy; van Marrewijk, Corine; Bowen, David; Hellstrom-Lindberg, Eva; Tatic, Aurelia; Symeonidis, Argiris; Huls, Gerwin; Cermak, Jaroslav; van de Loosdrecht, Arjan A.; Garelius, Hege; Culligan, Dominic; Macheta, Mac; Spanoudakis, Michail; Panagiotidis, Panagiotis; Krejci, Marta; Blijlevens, Nicole; Langemeijer, Saskia; Droste, Jackie; Swinkels, Dorine W.; Smith, Alex; de Witte, Theo 分享 收藏 分享 收藏 Cytomorphology review of 100 newly diagnosed lower-risk MDS patients in the European LeukemiaNet MDS (EUMDS) registry reveals a high inter-observer concordance在欧洲白血病网MDS (EUMDS) 注册表中对100名新诊断的低风险MDS患者进行的细胞形态学审查显示，观察者之间具有很高的一致性de Swart, Louise; Smith, Alex; MacKenzie, Marius; Symeonidis, Argiris; Neukirchen, Judith; Mikulenkova, Dana; Vallespi, Teresa; Zini, Gina; Paszkowska-Kowalewska, Malgorzata; Kruger, Anton; Saft, Leonie; Fenaux, Pierre; Bowen, David; Hellstrom-Lindberg, Eva; Cermak, Jaroslav; Stauder, Reinhard; Tatic, Aurelia; Holm, Mette Skov; Malcovati, Luca; Madry, Krzysztof; Droste, Jackie; Blijlevens, Nicole; de Witte, Theo; Germing, Ulrich 分享 收藏 
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