未登录 PRIMUS: a precision medicine platform reusing clinical trials and registry data to support treatment selection in multiple sclerosis PRIMUS：一个利用临床 trial 和注册数据支持多发性硬化症治疗选择的精准医学平台 Stanislas Demuth, MD, PhD; Igor Faddeenkov, MSc; Julien Paris, MSc; Olivia Rousseau, MSc; Béatrice Baciotti, MIM; Marianne Payet, PhD; Romain Casey, PhD; Sandra Vukusic, MD, PhD; Senan Doyle, PhD; Guillaume Jarre, PhD; Nicolas Vince, PhD; Sophie Limou, PhD; Jérôme De Sèze, MD, PhD; Anne Kerbrat, MD, PhD; David Laplaud, MD, PhD; Gilles Edan, MD, PhD; Pierre-Antoine Gourraud, PhD, MPH; for the PRIMUS Consortium 分享 收藏
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Limited added value of systematic spinal cord MRI vs brain MRI alone to classify patients with MS as active or inactive during follow-up 与仅进行脑部MRI相比，系统性的脊髓MRI在随访期间对将多发性硬化患者分类为活动期或非活动期具有有限的附加价值。 Hong, Jeremy; Gaubert, Malo; Lefort, Mathilde; Ferre, Jean Christophe; Le Page, Emmanuelle; Michel, Laure; Labauge, Pierre; Pelletier, Jean; de Seze, Jerome; Durand-Dubief, Francoise; Cotton, Francois; Edan, Gilles; Bannier, Elise; Combes, Benoit; Kerbrat, Anne 分享 收藏
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Blood immunophenotyping of multiple sclerosis patients at diagnosis identifies a classical monocyte subset associated to disease evolution Rodriguez, Stephane; Couloume, Laura; Ferrant, Juliette; Vince, Nicolas; Mandon, Marion; Jean, Rachel; Monvoisin, Celine; Leonard, Simon; Le Gallou, Simon; Silva, Nayane S. B.; Bourguiba-Hachemi, Sonia; Laplaud, David; Garcia, Alexandra; Casey, Romain; Zephir, Helene; Kerbrat, Anne; Edan, Gilles; Lepage, Emmanuelle; Thouvenot, Eric; Ruet, Aurelie; Mathey, Guillaume; Gourraud, Pierre-Antoine; Tarte, Karin; Delaloy, Celine; Ame, Patricia; Roussel, Mikael; Michel, Laure; OFSEP Investigators 分享 收藏
Microstructural Damage and Repair in the Spinal Cord of Patients With Early Multiple Sclerosis and Association With Disability at 5 Years Gaubert, Malo; Combes, Benoit; Bannier, Elise; Masson, Arthur; Caron, Vivien; Baudron, Gaelle; Ferre, Jean-Christophe; Michel, Laure; Le Page, Emmanuelle; Stankoff, Bruno; Edan, Gilles; Bodini, Benedetta; Kerbrat, Anne 分享 收藏
Long-term follow-up of patients with a first clinical demyelinating event (clinically isolated syndrome) who received cladribine tablets in CLASSIC-MS: Findings for the ORACLE-MS cohort 在经典-MS中接受克拉屈滨片治疗的首次临床脱髓鞘事件 (临床孤立综合征) 患者的长期随访: ORACLE-MS队列的发现 Giovannoni, Gavin; Boyko, Alexey; Correale, Jorge; Edan, Gilles; Freedman, Mark S.; Montalban, Xavier; Rammohan, Kottil; Stefoski, Dusan; Yamout, Bassem; Leist, Thomas; Aydemir, Aida; Borsi, Laszlo; di Cantogno, Elisabetta Verdun 分享 收藏
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Long-term follow-up of patients with relapsing multiple sclerosis from the CLARITY/CLARITY Extension cohort of CLASSIC-MS: An ambispective study 来自经典MS的CLARITY/CLARITY扩展队列的复发性多发性硬化症患者的长期随访: 一项前瞻性研究 Giovannoni, Gavin; Boyko, Alexey; Correale, Jorge; Edan, Gilles; Freedman, Mark S.; Montalban, Xavier; Rammohan, Kottil; Stefoski, Dusan; Yamout, Bassem; Leist, Thomas; Aydemir, Aida; Borsi, Laszlo; di Cantogno, Elisabetta Verdun 分享 收藏
Multiple sclerosis clinical decision support system based on projection to reference datasets Ed-driouch, Chadia; Cheneau, Florent; Simon, Francoise; Pasquier, Guillaume; Combes, Benoit; Kerbrat, Anne; Le Page, Emmanuelle; Limou, Sophie; Vince, Nicolas; Laplaud, David-Axel; Mars, Franck; Dumas, Cedric; Edan, Gilles; Gourraud, Pierre-Antoine 分享 收藏
Updated Results of the COVID-19 in MS Global Data Sharing Initiative Anti-CD20 and Other Risk Factors Associated With COVID-19 Severity MS全球数据共享倡议Anti-CD20和其他与新型冠状病毒肺炎严重程度相关的风险因素新型冠状病毒肺炎的更新结果 Simpson-Yap, Steve; Pirmani, Ashkan; Kalincik, Tomas; De Brouwer, Edward; Geys, Lotte; Parciak, Tina; Helme, Anne; Rijke, Nick; Hillert, Jan A.; Moreau, Yves; Edan, Gilles; Sharmin, Sifat; Spelman, Tim; McBurney, Robert; Schmidt, Hollie; Bergmann, Arnfin B.; Braune, Stefan; Stahmann, Alexander; Middleton, Rod M.; Salter, Amber; Bebo, Bruce; van der Walt, Anneke; Butzkueven, Helmut; Ozakbas, Serkan; Boz, Cavit; Karabudak, Rana; Alroughani, Raed; Rojas, Juan, I; van der Mei, Ingrid A.; do Olival, Guilherme Sciascia; Magyari, Melinda; Alonso, Ricardo N.; Nicholas, Richard S.; Chertcoff, Anibal S.; de Torres, Ana Zabalza; Arrambide, Georgina; Nag, Nupur; Descamps, Annabel; Costers, Lars; Dobson, Ruth; Miller, Aleisha; Rodrigues, Paulo; Prckovska, Vesna; Comi, Giancarlo; Peeters, Liesbet M. 分享 收藏
Disease Reactivation After Cessation of Disease-Modifying Therapy in Patients With Relapsing-Remitting Multiple Sclerosis Roos, Izanne; Malpas, Charles; Leray, Emmanuelle; Casey, Romain; Horakova, Dana; Havrdova, Eva Kubala; Debouverie, Marc; Patti, Francesco; De Seze, Jerome; Izquierdo, Guillermo; Eichau, Sara; Edan, Gilles; Prat, Alexandre; Girard, Marc; Ozakbas, Serkan; Grammond, Pierre; Zephir, Helene; Ciron, Jonathan; Maillart, Elisabeth; Moreau, Thibault; Amato, Maria Pia; Labauge, Pierre; Alroughani, Raed; Buzzard, Katherine; Skibina, Olga; Terzi, Murat; Laplaud, David Axel; Berger, Eric; Grand'Maison, Francois; Lebrun-Frenay, Christine; Cartechini, Elisabetta; Boz, Cavit; Lechner-Scott, Jeannette; Clavelou, Pierre; Stankoff, Bruno; Prevost, Julie; Kappos, Ludwig; Pelletier, Jean; Shaygannejad, Vahid; Yamout, Bassem, I; Khoury, Samia J.; Gerlach, Oliver; Spitaleri, Daniele L. A.; Van Pesch, Vincent; Gout, Olivier; Turkoglu, Recai; Heinzlef, Olivier; Thouvenot, Eric; McCombe, Pamela Ann; Soysal, Aysun; Bourre, Bertrand; Slee, Mark; Castillo-Trivino, Tamara; Bakchine, Serge; Ampapa, Radek; Butler, Ernest Gerard; Wahab, Abir; Macdonell, Richard A.; Aguera-Morales, Eduardo; Cabre, Philippe; Ben, Nasr Haifa; Van der Walt, Anneke; Laureys, Guy; Van Hijfte, Liesbeth; Ramo-Tello, Cristina M.; Maubeuge, Nicolas; Hodgkinson, Suzanne; Sanchez-Menoyo, Jose Luis; Barnett, Michael H.; Labeyrie, Celine; Vucic, Steve; Sidhom, Youssef; Gouider, Riadh; Csepany, Tunde; Sotoca, Javier; de Gans, Koen; Al-Asmi, Abdullah; Fragoso, Yara Dadalti; Vukusic, Sandra; Butzkueven, Helmut; Kalincik, Tomas 分享 收藏
Impact of methodological choices in comparative effectiveness studies: application in natalizumab versus fingolimod comparison among patients with multiple sclerosis Lefort, M.; Sharmin, S.; Andersen, J. B.; Vukusic, S.; Casey, R.; Debouverie, M.; Edan, G.; Ciron, J.; Ruet, A.; De Seze, J.; Maillart, E.; Zephir, H.; Labauge, P.; Defer, G.; Lebrun-Frenay, C.; Moreau, T.; Berger, E.; Clavelou, P.; Pelletier, J.; Stankoff, B.; Gout, O.; Thouvenot, E.; Heinzlef, O.; Al-Khedr, A.; Bourre, B.; Casez, O.; Cabre, P.; Montcuquet, A.; Wahab, A.; Camdessanche, J. P.; Maurousset, A.; Ben Nasr, H.; Hankiewicz, K.; Pottier, C.; Maubeuge, N.; Nifle, C.; Laplaud, D. A.; Horakova, D.; Dimitri-Boulos, D.; Havrdova, E. K.; Alroughani, R.; Izquierdo, G.; Eichau, S.; Ozakbas, S.; Patti, F.; Onofrj, M.; Lugaresi, A.; Terzi, M.; Grammond, P.; Grand'Maison, F.; Yamout, B.; Prat, A.; Girard, M.; Duquette, P.; Boz, C.; Trojano, M.; McCombe, P.; Slee, M.; Lechner-Scott, J.; Turkoglu, R.; Sola, P.; Ferraro, D.; Granella, F.; Shaygannejad, V; Prevost, J.; Maimone, D.; Skibina, O.; Buzzard, K.; Van der Walt, A.; Karabudak, R.; Van Wijmeersch, B.; Csepany, T.; Spitaleri, D.; Vucic, S.; Koch-Henriksen, N.; Sellebjerg, F.; Soerensen, P. S.; Christensen, C. C. Hilt; Rasmussen, P., V; Jensen, M. B.; Frederiksen, J. L.; Bramow, S.; Mathiesen, H. K.; Schreiber, K., I; Butzkueven, H.; Magyari, M.; Kalincik, T.; Leray, E. 分享 收藏
Comparative Effectiveness of Natalizumab Versus Anti-CD20 in Highly Active Relapsing-Remitting Multiple Sclerosis After Fingolimod Withdrawal Rollot, Fabien; Couturier, Justine; Casey, Romain; Wiertlewski, Sandrine; Debouverie, Marc; Pelletier, Jean; De Seze, Jerome; Labauge, Pierre; Ruet, Aurelie; Thouvenot, Eric; Ciron, Jonathan; Berger, Eric; Gout, Olivier; Clavelou, Pierre; Stankoff, Bruno; Casez, Olivier; Bourre, Bertrand; Zephir, Helene; Moreau, Thibault; Lebrun-Frenay, Christine; Maillart, Elisabeth; Edan, Gilles; Neau, Jean-Philippe; Montcuquet, Alexis; Cabre, Philippe; Camdessanche, Jean-Philippe; Defer, Gilles; Ben Nasr, Haifa; Maurousset, Aude; Hankiewicz, Karolina; Pottier, Corinne; Leray, Emmanuelle; Vukusic, Sandra; Laplaud, David-Axel 分享 收藏
A Clinically-Compatible Workflow for Computer-Aided Assessment of Brain Disease Activity in Multiple Sclerosis Patients Combes, Benoit; Kerbrat, Anne; Pasquier, Guillaume; Commowick, Olivier; Le Bon, Brandon; Galassi, Francesca; L'Hostis, Philippe; El Graoui, Nora; Chouteau, Raphael; Cordonnier, Emmanuel; Edan, Gilles; Ferre, Jean-Christophe 分享 收藏
Natalizumab Versus Fingolimod in Patients with Relapsing-Remitting Multiple Sclerosis: A Subgroup Analysis From Three International Cohorts Sharmin, Sifat; Lefort, Mathilde; Andersen, Johanna Balslev; Leray, Emmanuelle; Horakova, Dana; Havrdova, Eva Kubala; Alroughani, Raed; Izquierdo, Guillermo; Ozakbas, Serkan; Patti, Francesco; Onofrj, Marco; Lugaresi, Alessandra; Terzi, Murat; Grammond, Pierre; Grand'Maison, Francois; Yamout, Bassem; Prat, Alexandre; Girard, Marc; Duquette, Pierre; Boz, Cavit; Trojano, Maria; McCombe, Pamela; Slee, Mark; Lechner-Scott, Jeannette; Turkoglu, Recai; Sola, Patrizia; Ferraro, Diana; Granella, Franco; Prevost, Julie; Maimone, Davide; Skibina, Olga; Buzzard, Katherine; Van der Walt, Anneke; Van Wijmeersch, Bart; Csepany, Tunde; Spitaleri, Daniele; Vucic, Steve; Casey, Romain; Debouverie, Marc; Edan, Gilles; Ciron, Jonathan; Ruet, Aurelie; De Seze, Jerome; Maillart, Elisabeth; Zephir, Helene; Labauge, Pierre; Defer, Gilles; Lebrun-Frenay, Christine; Moreau, Thibault; Berger, Eric; Clavelou, Pierre; Pelletier, Jean; Stankoff, Bruno; Gout, Olivier; Thouvenot, Eric; Heinzlef, Olivier; Al-Khedr, Abullatif; Bourre, Bertrand; Casez, Olivier; Cabre, Philippe; Montcuquet, Alexis; Wahab, Abir; Camdessanche, Jean-Philippe; Maurousset, Aude; Patry, Ivania; Hankiewicz, Karolina; Pottier, Corinne; Maubeuge, Nicolas; Labeyrie, Celine; Nifle, Chantal; Laplaud, David; Koch-Henriksen, Niels; Sellebjerg, Finn Thorup; Soerensen, Per Soelberg; Pfleger, Claudia Christina; Rasmussen, Peter Vestergaard; Jensen, Michael Broksgaard; Frederiksen, Jette Lautrup; Bramow, Stephan; Mathiesen, Henrik Kahr; Schreiber, Karen Ingrid; Magyari, Melinda; Vukusic, Sandra; Butzkueven, Helmut; Kalincik, Tomas 分享 收藏
Effects of High- and Low-Efficacy Therapy in Secondary Progressive Multiple Sclerosis Roos, Izanne; Leray, Emmanuelle; Casey, Romain; Horakova, Dana; Havrdova, Eva; Izquierdo, Guillermo; Madueno, Sara Eichau; Patti, Francesco; Edan, Gilles; Debouverie, Marc; Pelletier, Jean; Ozakbas, Serkan; Amato, Maria Pia; Clavelou, Pierre; Grammond, Pierre; Boz, Cavit; Buzzard, Katherine; Skibina, Olga; Ciron, Jonathan; Gerlach, Oliver; Grand'Maison, Francois; Lechner-Scott, Jeannette; Malpas, Charles; Butzkueven, Helmut; Vukusic, Sandra; Kalincik, Tomas 分享 收藏
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