未登录Genetic mapping across autoimmune diseases reveals shared associations and mechanisms跨自身免疫性疾病的遗传图谱揭示了共享的关联和机制
Lincoln, Matthew R.; Connally, Noah; Axisa, Pierre-Paul; Gasperi, Christiane; Mitrovic, Mitja; van Heel, David; Wijmenga, Cisca; Withoff, Sebo; Jonkers, Iris H.; Padyukov, Leonid; Beecham, Ashley H.; Patsopoulos, Nikolaos A.; Cotsapas, Chris; Booth, David; Goris, An; Oturai, Annette; Saarela, Janna; Fontaine, Betrand; Hemmer, Bertrand; Claes, Martin; Zipp, Frauke; D'Alfonso, Sandra; Martinelli-Boneschi, Filippo; Taylor, Bruce; Harbo, Hanne F.; Kockum, Ingrid; Hillert, Jan; Olsson, Tomas; Oksenberg, Jorge R.; Hintzen, Rogier; Barcellos, Lisa F.; Alfredsson, Lars; Esposito, Federica; Martin, Roland; Haines, Jonathan L.; Pericak-Vance, Margaret A.; Ivinson, Adrian J.; Stewart, Graeme; Hafler, David; Hauser, Stephen L.; Compston, Alastair; Mcvean, Gil; De Jager, Philip; Sawcer, Stephen J.; Mccauley, Jakob L.; Rich, Stephen S.; Graham, Robert R.; Gaffney, Patrick M.; Langefeld, Carl D.; Vyse, Timothy J.; Hafler, David A.; Chun, Sung; Sunyaev, Shamil R.; Cotsapas, Chris .png)
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收藏分享 收藏 分享 收藏 A systems biology approach uncovers cell-specific gene regulatory effects of genetic associations in multiple sclerosis (vol 10, 2236, 2019)Madireddy, Lohith; Patsopoulos, Nikolaos A.; Cotsapas, Chris; Bos, Steffan D.; Beecham, Ashley; McCauley, Jacob; Kim, Kicheol; Jia, Xiaoming; Santaniello, Adam; Caillier, Stacy J.; Andlauer, Till F. M.; Barcellos, Lisa F.; Berge, Tone; Bernardinelli, Luisa; Martinelli-Boneschi, Filippo; Booth, David R.; Briggs, Farren; Celius, Elisabeth G.; Comabella, Manuel; Comi, Giancarlo; Cree, Bruce A. C.; D'Alfonso, Sandra; Dedham, Katrina; Duquette, Pierre; Dardiotis, Efthimios; Esposito, Federica; Fontaine, Bertrand; Gasperi, Christiane; Goris, An; Dubois, Benedicte; Gourraud, Pierre-Antoine; Hadjigeorgiou, Georgios; Haines, Jonathan; Hawkins, Clive; Hemmer, Bernhard; Hintzen, Rogier; Horakova, Dana; Isobe, Noriko; Kalra, Seema; Kira, Jun-ichi; Khalil, Michael; Kockum, Ingrid; Lill, Christina M.; Lincoln, Matthew R.; Luessi, Felix; Martin, Roland; Oturai, Annette; Palotie, Aarno; Pericak-Vance, Margaret A.; Henry, Roland; Saarela, Janna; Ivinson, Adrian; Olsson, Tomas; Taylor, Bruce V.; Stewart, Graeme J.; Harbo, Hanne F.; Compston, Alastair; Hauser, Stephen L.; Hafler, David A.; Zipp, Frauke; De Jager, Philip; Sawcer, Stephen; Oksenberg, Jorge R.; Baranzini, Sergio E. 分享 收藏 A systems biology approach uncovers cell-specific gene regulatory effects of genetic associations in multiple sclerosis一种系统生物学方法揭示了多发性硬化症中遗传关联的细胞特异性基因调控作用Madireddy, Lohith; Patsopoulos, Niklaos A.; Cotsapas, Chris; Bos, Steffan D.; Beecham, Ashley; McCauley, Jacob; Kim, Kicheol; Jia, Xiaoming; Santaniello, Adam; Caillier, Stacy J.; Andlauer, Till F. M.; Barcellos, Lisa F.; Berge, Tone; Bernardinelli, Luisa; Martinelli-Boneschi, Filippo; Booth, David R.; Briggs, Farren; Celius, Elisabeth G.; Comabella, Manuel; Comi, Giancarlo; Cree, Bruce A. C.; D'Alfonso, Sandra; Dedham, Katrina; Duquette, Pierre; Efthimios, Dardiotis; Esposito, Federica; Fontaine, Bertrand; Gasperi, Christiane; Goris, An; Dubois, Benedicte; Gourraud, Pierre-Antoine; Hadjigeorgiou, Georgios; Haines, Jonathan; Hawkins, Clive; Hemmer, Bernhard; Hintzen, Rogier; Horakova, Dana; Isobe, Noriko; Kalra, Seema; Kira, Jun-ichi; Khalil, Michael; Kockum, Ingrid; Lill, Christina M.; Lincoln, Matthew R.; Luessi, Felix; Martin, Roland; Oturai, Annette; Palotie, Aarno; Pericak-Vance, Margaret A.; Henry, Roland; Saarela, Janna; Ivinson, Adrian; Olsson, Tomas; Taylor, Bruce V.; Stewart, Graeme J.; Harbo, Hanne F.; Compston, Alastair; Hauser, Stephen L.; Hafler, David A.; Zipp, Frauke; De Jager, Philip; Sawcer, Stephen; Oksenberg, Jorge R.; Baranzini, Sergio E. 分享 收藏 分享 收藏 Multiple sclerosis risk variants alter expression of co-stimulatory genes in B cells多发性硬化风险变异改变b细胞共刺激基因的表达Smets, Ide; Fiddes, Barnaby; Garcia-Perez, Josselyn E.; He, Di; Mallants, Klara; Liao, Wenjia; Dooley, James; Wang, George; Humblet-Baron, Stephanie; Dubois, Benedicte; Compston, Alastair; Jones, Joanne; Coles, Alasdair; Liston, Adrian; Ban, Maria; Goris, An; Sawcer, Stephen 分享 收藏 分享 收藏 分享 收藏 分享 收藏 Resolving TYK2 locus genotype-to-phenotype differences in autoimmunityDendrou, Calliope A.; Cortes, Adrian; Shipman, Lydia; Evans, Hayley G.; Attfield, Kathrine E.; Jostins, Luke; Barber, Thomas; Kaur, Gurman; Kuttikkatte, Subita Balaram; Leach, Oliver A.; Desel, Christiane; Faergeman, Soren L.; Cheeseman, Jane; Neville, Matt J.; Sawcer, Stephen; Compston, Alastair; Johnson, Adam R.; Everett, Christine; Bell, John I.; Karpe, Fredrik; Ultsch, Mark; Eigenbrot, Charles; McVean, Gil; Fugger, Lars 分享 收藏 NR1H3 p.Arg415Gln Is Not Associated to Multiple Sclerosis RiskAntel, Jack; Ban, Maria; Baranzini, Sergio; Barcellos, Lisa; Barizzone, Nadia; Beecham, Ashley; Berge, Tone; Bernardinelli, Luisa; Booth, David; Bos, Steffan; Buck, Dorothea; Butkiewicz, Mariusz; Celius, Elisabeth G.; Comabella, Manuel; Compston, Alastair; Dedham, Katrina; Cotsapas, Chris; Alfonso, Sandra D'; De Jager, Phil; Dubois, Benedicte; Duquette, Pierre; Fontaine, Bertrand; Gasperi, Christiane; Gil, Elia; Goris, An; Gourraud, Pierre Antoine; Graetz, Christiane; Gyllenberg, Alexandra; Hadjigeorgiou, Georgios; Hafler, David; Hribko, Deanna; Haines, Jonathan; Harbo, Hanne; Hauser, Stephen; Warto, Shannon; Hawkins, Clive; Hemmer, Bernhard; Henry, Roland; Hintzen, Rogier; Horakova, Dana; Ivinson, Adrian; Howard, Melissa; Jelcic, Ilijas; Kaskow, Belinda; Kira, Jun-Ichi; Kleinova, Pavlina; Kockum, Ingrid; Kucerova, Karolina; Lill, Christina; Luessi, Felix; Malhotra, Sunny; Martin, Roland; Martinelli, Filippo; Matsushita, Takuya; McCabe, Cristin; McCauley, Jacob; Mescheriakkova, Julia; Mitrovic, Mitja; Moen, Stine-Marit; Montalban, Xavier; Muhlau, Mark; Nakmura, Yuri; Oksenberg, Jorge; Olsson, Tomas; Oturai, Annette; Palotie, Aarno; Patsopoulos, Nikolaos; Pavlicova, Jana; Pericak-Vance, Peggy; Piehl, Fredrik; Rebeix, Isabelle; Rioux, John; Saarela, Janna; Sawcer, Stephen; Sellebjerg, Finn; Sondergaard, Helle Bach; Sorensen, Per Soelberg; Sospedra, Mireia; Spurkland, Anne; Stewart, Graeme; Taylor, Bruce; Uitterlinden, Andre; Van Duijn, Cornelia; Zipp, Frauke 分享 收藏 分享 收藏 分享 收藏 分享 收藏 分享 收藏 分享 收藏 Human autoimmunity after lymphocyte depletion is caused by homeostatic T-cell proliferation淋巴细胞耗竭后的人类自身免疫是由稳态T细胞增殖引起的Jones, Joanne L.; Thompson, Sara A. J.; Loh, Priscilla; Davies, Jessica L.; Tuohy, Orla C.; Curry, Allison J.; Azzopardi, Laura; Hill-Cawthorne, Grant; Fahey, Michael T.; Compston, Alastair; Coles, Alasdair J. 分享 收藏 分享 收藏 Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis对免疫相关基因座的分析确定了多发性硬化症的48个新的易感性变异Beecham, Ashley H.; Patsopoulos, Nikolaos A.; Xifara, Dionysia K.; Davis, Mary F.; Kemppinen, Anu; Cotsapas, Chris; Shah, Tejas S.; Spencer, Chris; Booth, David; Goris, An; Oturai, Annette; Saarela, Janna; Fontaine, Bertrand; Hemmer, Bernhard; Martin, Claes; Zipp, Frauke; D'Alfonso, Sandra; Martinelli-Boneschi, Filippo; Taylor, Bruce; Harbo, Hanne F.; Kockum, Ingrid; Hillert, Jan; Olsson, Tomas; Ban, Maria; Oksenberg, Jorge R.; Hintzen, Rogier; Barcellos, Lisa F.; Agliardi, Cristina; Alfredsson, Lars; Alizadeh, Mehdi; Anderson, Carl; Andrews, Robert; Sondergaard, Helle Bach; Baker, Amie; Band, Gavin; Baranzini, Sergio E.; Barizzone, Nadia; Barrett, Jeffrey; Bellenguez, Celine; Bergamaschi, Laura; Bernardinelli, Luisa; Berthele, Achim; Biberacher, Viola; Binder, Thomas M. C.; Blackburn, Hannah; Bomfim, Izaura L.; Brambilla, Paola; Broadley, Simon; Brochet, Bruno; Brundin, Lou; Buck, Dorothea; Butzkueven, Helmut; Caillier, Stacy J.; Camu, William; Carpentier, Wassila; Cavalla, Paola; Celius, Elisabeth G.; Coman, Irene; Comi, Giancarlo; Corrado, Lucia; Cosemans, Leentje; Cournu-Rebeix, Isabelle; Cree, Bruce A. C.; Cusi, Daniele; Damotte, Vincent; Defer, Gilles; Delgado, Silvia R.; Deloukas, Panos; di Sapio, Alessia; Dilthey, Alexander T.; Donnelly, Peter; Dubois, Benedicte; Duddy, Martin; Edkins, Sarah; Elovaara, Irina; Esposito, Federica; Evangelou, Nikos; Fiddes, Barnaby; Field, Judith; Franke, Andre; Freeman, Colin; Frohlich, Irene Y.; Galimberti, Daniela; Gieger, Christian; Gourraud, Pierre-Antoine; Graetz, Christiane; Graham, Andrew; Grummel, Verena; Guaschino, Clara; Hadjixenofontos, Athena; Hakonarson, Hakon; Halfpenny, Christopher; Hall, Gillian; Hall, Per; Hamsten, Anders; Harley, James; Harrower, Timothy; Hawkins, Clive; Hellenthal, Garrett; Hillier, Charles; Hobart, Jeremy; Hoshi, Muni; Hunt, Sarah E.; Jagodic, Maja; Jelcic, Ilijas; Jochim, Angela; Kendall, Brian; Kermode, Allan; Kilpatrick, Trevor; Koivisto, Keijo; Konidari, Ioanna; Korn, Thomas; Kronsbein, Helena; Langford, Cordelia; Larsson, Malin; Lathrop, Mark; Lebrun-Frenay, Christine; Lechner-Scott, Jeannette; Lee, Michelle H.; Leone, Maurizio A.; Leppa, Virpi; Liberatore, Giuseppe; Lie, Benedicte A.; Lill, Christina M.; Linden, Magdalena; Link, Jenny; Luessi, Felix; Lycke, Jan; Macciardi, Fabio; Mannisto, Satu; Manrique, Clara P.; Martin, Roland; Martinelli, Vittorio; Mason, Deborah; Mazibrada, Gordon; McCabe, Cristin; Mero, Inger-Lise; Mescheriakova, Julia; Moutsianas, Loukas; Myhr, Kjell-Morten; Nagels, Guy; Nicholas, Richard; Nilsson, Petra; Piehl, Fredrik; Pirinen, Matti; Price, Sian E.; Quach, Hong; Reunanen, Mauri; Robberecht, Wim; Robertson, Neil P.; Rodegher, Mariaemma; Rog, David; Salvetti, Marco; Schnetz-Boutaud, Nathalie C.; Sellebjerg, Finn; Selter, Rebecca C.; Schaefer, Catherine; Shaunak, Sandip; Shen, Ling; Shields, Simon; Siffrin, Volker; Slee, Mark; Sorensen, Per Soelberg; Sorosina, Melissa; Sospedra, Mireia; Spurkland, Anne; Strange, Amy; Sundqvist, Emilie; Thijs, Vincent; Thorpe, John; Ticca, Anna; Tienari, Pentti; van Duijn, Cornelia; Visser, Elizabeth M.; Vucic, Steve; Westerlind, Helga; Wiley, James S.; Wilkins, Alastair; Wilson, James F.; Winkelmann, Juliane; Zajicek, John; Zindler, Eva; Haines, Jonathan L.; Pericak-Vance, Margaret A.; Ivinson, Adrian J.; Stewart, Graeme; Hafler, David; Hauser, Stephen L.; Compston, Alastair; McVean, Gil; De Jager, Philip; Sawcer, Stephen J.; McCauley, Jacob L. 分享 收藏 
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