Irving M. Shapiro - Publications, H-index & Citations

Irving M. Shapiro

Thomas Jefferson University

86H指数

372论文数

3.4W被引数

收录论文 107

发表时间

Skeletal and dental tissue mineralization: The potential role of the endoplasmic reticulum/Golgi complex and the endolysosomal and autophagic transport systems

BONE

IF3.6

2025-04-01

OAAI

Shapiro, Irving M.; Risbud, Makarand, V; Tang, Tengteng; Landis, William J.

Toward understanding the cellular control of vertebrate mineralization: The potential role of mitochondria

BONE

IF3.6

2024-08-01

PREAI

Shapiro, Irving M.; Risbud, Makarand V.; Landis, William J.

GLUT1 is redundant in hypoxic and glycolytic nucleus pulposus cells of the intervertebral disc

JCI INSIGHT

IF6.1

2023-04-24

OAAI

Johnston, Shira N. .; Silagi, Elizabeth S. .; Madhu, Vedavathi; Nguyen, Duc H. .; Shapiro, Irving M. .; Risbud, Makarand V.

Microbubble cavitation restores Staphylococcus aureus antibiotic susceptibility in vitro and in a septic arthritis model

COMMUNICATIONS BIOLOGY

IF5.1

2023-04-17

OAAI

Zhao, Neil; Curry, Dylan; Evans, Rachel E. E.; Isguven, Selin; Freeman, Theresa; Eisenbrey, John R. R.; Forsberg, Flemming; Gilbertie, Jessica M. M.; Boorman, Sophie; Hilliard, Rachel; Dastgheyb, Sana S. S.; Machado, Priscilla; Stanczak, Maria; Harwood, Marc; Chen, Antonia F. F.; Parvizi, Javad; Shapiro, Irving M. M.; Hickok, Noreen J. J.; Schaer, Thomas P. P.

Conditional Deletion of HIF-2α in Mouse Nucleus Pulposus Reduces Fibrosis and Provides Mild and Transient Protection From Age-Dependent Structural Changes in Intervertebral Disc

JOURNAL OF BONE AND MINERAL RESEARCH

IF5.9

2022-09-19

OAAI

Johnston, Shira N.; Madhu, Vedavathi; Shapiro, Irving M.; Risbud, Makarand, V

Long-term treatment with senolytic drugs Dasatinib and Quercetin ameliorates age-dependent intervertebral disc degeneration in mice

NATURE COMMUNICATIONS

IF15.7

2021-09-03

211

OAAI

Novais, Emanuel J.; Tran, Victoria A.; Johnston, Shira N.; Darris, Kayla R.; Roupas, Alex J.; Sessions, Garrett A.; Shapiro, Irving M.; Diekman, Brian O.; Risbud, Makarand, V

The role of HIF proteins in maintaining the metabolic health of the intervertebral disc

NATURE REVIEWS RHEUMATOLOGY

IF32.7

2021-06-03

OAAI

Silagi, Elizabeth S.; Schipani, Ernestina; Shapiro, Irving M.; Risbud, Makarand V.

TonEBP regulates the hyperosmotic expression of aquaporin 1 and 5 in the intervertebral disc

SCIENTIFIC REPORTS

IF3.9

2021-02-04

OAAI

Snuggs, J. W.; Tessier, S.; Bunning, R. A. B.; Shapiro, I. M.; Risbud, M. V.; Le Maitre, C. L.

Comparison of inbred mouse strains shows diverse phenotypic outcomes of intervertebral disc aging

AGING CELL

IF7.1

2020-04-22

OAAI

Novais, Emanuel J.; Tran, Victoria A.; Miao, Jingya; Slaver, Katie; Sinensky, Andrew; Dyment, Nathaniel A.; Addya, Sankar; Szeri, Flora; van de Wetering, Koen; Shapiro, Irving M.; Risbud, Makarand V.

Hypoxic Regulation of Mitochondrial Metabolism and Mitophagy in Nucleus Pulposus Cells Is Dependent on HIF-1α-BNIP3 Axis

JOURNAL OF BONE AND MINERAL RESEARCH

IF5.9

2020-04-06

OAAI

Madhu, Vedavathi; Boneski, Paige K.; Silagi, Elizabeth; Qiu, Yunping; Kurland, Irwin; Guntur, Anyonya R.; Shapiro, Irving M.; Risbud, Makarand, V

Arp2/3 inactivation causes intervertebral disc and cartilage degeneration with dysregulated TonEBP-mediated osmoadaptation

JCI INSIGHT

IF6.1

2020-02-27

OAAI

Tessier, Steven; Doolittle, Alexandra C.; Sao, Kimheak; Rotty, Jeremy D.; Bear, James E.; Ulici, Veronica; Loeser, Richard F.; Shapiro, Irving M.; Diekman, Brian O.; Risbud, Makarand, V

Differential Effect of Long-Term Systemic Exposure of TNFα on Health of the Annulus Fibrosus and Nucleus Pulposus of the Intervertebral Disc

JOURNAL OF BONE AND MINERAL RESEARCH

IF5.9

2019-12-04

OAAI

Gorth, Deborah J.; Ottone, Olivia K.; Shapiro, Irving M.; Risbud, Makarand V.

Lactate Efflux From Intervertebral Disc Cells Is Required for Maintenance of Spine Health

JOURNAL OF BONE AND MINERAL RESEARCH

IF5.9

2019-11-06

OAAI

Silagi, Elizabeth S.; Novais, Emanuel J.; Bisetto, Sara; Telonis, Aristeidis G.; Snuggs, Joseph; Le Maitre, Christine L.; Qiu, Yunping; Kurland, Irwin J.; Shapiro, Irving M.; Philp, Nancy J.; Risbud, Makarand V.

Nucleus pulposus primary cilia alter their length in response to changes in extracellular osmolarity but do not control TonEBP-mediated osmoregulation

SCIENTIFIC REPORTS

IF3.9

2019-10-29

OAAI

Choi, Hyowon; Madhu, Vedavathi; Shapiro, Irving M.; Risbud, Makarand V.

Tendinosis develops from age- and oxygen tension-dependent modulation of Rac1 activity

AGING CELL

IF7.1

2019-04-02

OAAI

McBeath, Rowena; Edwards, Richard W.; O'Hara, Brian J.; Maltenfort, Mitchell G.; Parks, Susan M.; Steplewski, Andrzej; Osterman, A. Lee; Shapiro, Irving M.

A New Understanding of the Role of IL-1 in Age-Related Intervertebral Disc Degeneration in a Murine Model

JOURNAL OF BONE AND MINERAL RESEARCH

IF5.9

2019-03-15

OAAI

Gorth, Deborah J.; Shapiro, Irving M.; Risbud, Makarand, V

Transgenic mice overexpressing human TNF-α experience early onset spontaneous intervertebral disc herniation in the absence of overt degeneration

CELL DEATH & DISEASE

IF9.6

2018-12-18

OAAI

Gorth, Deborah J.; Shapiro, Irving M.; Risbud, Makarand V.

COX-2 expression mediated by calcium-TonEBP signaling axis under hyperosmotic conditions serves osmoprotective function in nucleus pulposus cells

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2018-06-01

OAAI

Choi, Hyowon; Chaiyamongkol, Weera; Doolittle, Alexandra C.; Johnson, Zariel I.; Gogate, Shilpa S.; Schoepflin, Zachary R.; Shapiro, Irving M.; Risbud, Makarand V.

Expression of Carbonic Anhydrase III, a Nucleus Pulposus Phenotypic Marker, is Hypoxia-responsive and Confers Protection from Oxidative Stress-induced Cell Death

SCIENTIFIC REPORTS

IF3.9

2018-03-20

OAAI

Silagi, Elizabeth S.; Batista, Philip; Shapiro, Irving M.; Risbud, Makarand V.

TNF-α promotes nuclear enrichment of the transcription factor TonEBP/NFAT5 to selectively control inflammatory but not osmoregulatory responses in nucleus pulposus cells

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2017-10-01

OAAI

Johnson, Zariel I.; Doolittle, Alexandra C.; Snuggs, Joseph W.; Shapiro, Irving M.; Le Maitre, Christine L.; Risbud, Makarand V.

研究方向