David L. Brautigan - Publications, H-index & Citations

David L. Brautigan

University of Virginia

74H指数

386论文数

2.0W被引数

收录论文 125

发表时间

Human disease variants of KATNIP fail to support CILK1 activation and control of primary cilia KATNIP的人类疾病变异体无法支持CILK1的激活以及对初级纤毛的控制。

JOURNAL OF CELL SCIENCE

IF3.6

2025-10-01

PREAI

Carpenter, Evan H.; Chu, Cheuk Ying; Limerick, Ana; Brautigan, David L.; Fu, Zheng

An Epilepsy-Associated CILK1 Variant Compromises KATNIP Regulation and Impairs Primary Cilia and Hedgehog Signaling

CELLS

IF5.2

2024-07-26

OAAI

Limerick, Ana; McCabe, Ellie A.; Turner, Jacob S.; Kuang, Kevin W.; Brautigan, David L.; Hao, Yi; Chu, Cheuk Ying; Fu, Sean H.; Ahmadi, Sean; Xu, Wenhao; Fu, Zheng

The Scaffold Protein KATNIP Enhances CILK1 Control of Primary Cilia

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-09-04

OAAI

Turner, Jacob S.; Mccabe, Ellie A.; Kuang, Kevin W.; Gailey, Casey D.; Brautigan, David L.; Limerick, Ana; Wang, Elena X.; Fu, Zheng

Simian virus 40 small t antigen mediates conformation-dependent transfer of protein phosphatase 2A onto the androgen receptor

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

OAAI

Yang, CS; Vitto, MJ; Busby, SA; Garcia, BA; Kesler, CT; Gioeli, D; Shabanowitz, J; Hunt, DF; Rundell, K; Brautigan, DL; Paschal, BM

Ligand binding to the androgen receptor induces conformational changes that regulate phosphatase interactions

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

OAAI

Yang, Chun-Song; Xin, Hong-Wu; Kelley, Joshua B.; Spencer, Adam; Brautigan, David L.; Paschal, Bryce M.

Cytokine activation of p38 mitogen-activated protein kinase and apoptosis is opposed by alpha-4 targeting of protein phosphatase 2A for site-specific dephospholylation of MEK3

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

OAAI

Prickett, Todd D.; Brautigan, David L.

Targeting protein phosphatase 1 (PP1) to the actin cytoskeleton: the neurabin I/PP1 complex regulates cell morphology

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

120

OAAI

Oliver, CJ; Terry-Lorenzo, RT; Elliott, E; Bloomer, WAC; Li, S; Brautigan, DL; Colbran, RJ; Shenolikar, S

Transcriptome-wide association study and eQTL colocalization identify potentially causal genes responsible for human bone mineral density GWAS associations

ELIFE

IF0

2022-11-23

OAAI

Al-Barghouthi, Basel Maher; Rosenow, Will T.; Du, Kang-Ping; Heo, Jinho; Maynard, Robert; Mesner, Larry; Calabrese, Gina; Nakasone, Aaron; Senwar, Bhavya; Gerstenfeld, Louis; Larner, James; Ferguson, Virginia; Ackert-Bicknell, Cheryl; Morgan, Elise; Brautigan, David; Farber, Charles R.

Phosphorylase phosphatase and flash activation of skeletal muscle glycogen phosphorylase-A tribute to Edmond H. Fischer 磷酸化酶磷酸酶和骨骼肌糖原磷酸化酶的快速激活-向Edmond H. Fischer致敬

IUBMB LIFE

IF3.2

2022-11-02

OAAI

Brautigan, David L.

Animal Models of Hepatocellular Carcinoma for Local-Regional Intraarterial Therapies

RADIOLOGY-IMAGING CANCER

IF6.3

2022-07-01

OAAI

Chandra, Vishnu M.; Wilkins, Luke R.; Brautigan, David L.

Renal AT2 Receptors Mediate Natriuresis via Protein Phosphatase PP2A

CIRCULATION RESEARCH

IF16.2

2022-01-07

OAAI

Kemp, Brandon A.; Howell, Nancy L.; Gildea, John J.; Keller, Susanna R.; Brautigan, David L.; Carey, Robert M.

A non-canonical, interferon-independent signaling activity of cGAMP triggers DNA damage response signaling cGAMP的非规范，不依赖干扰素的信号传导活性触发DNA损伤反应信号传导

NATURE COMMUNICATIONS

IF15.7

2021-10-27

OAAI

Banerjee, Daipayan; Langberg, Kurt; Abbas, Salar; Odermatt, Eric; Yerramothu, Praveen; Volaric, Martin; Reidenbach, Matthew A.; Krentz, Kathy J.; Rubinstein, C. Dustin; Brautigan, David L.; Abbas, Tarek; Gelfand, Bradley D.; Ambati, Jayakrishna; Kerur, Nagaraj

Targeting protein phosphatase PP2A for cancer therapy: development of allosteric pharmaceutical agents

CLINICAL SCIENCE

IF7.7

2021-06-30

OAAI

Brautigan, David L.; Farrington, Caroline; Narla, Goutham

Biased activation of PP2A through selective heterotrimer binding and stabilization

CANCER RESEARCH

IF16.6

2020-08-15

PREAI

Leonard, Daniel; Huang, Wei; Izadmehr, Sudeh; O'Connor, Caitlin M.; Wiredja, Danica D.; Wang, Zhizhi; Zaware, Nilesh; Schlatzer, Daniela M.; Schuchner, Stefan; Kiselar, Janna; Chen, Yinghua; Vasireddi, Nikhil; Perl, Abbey L.; Glasky, Matthew D.; Xu, Wenqing; Brautigan, David L.; Ogris, Egon; Taylor, Derek J.; Narla, Goutham

Aurora B Kinase Promotes CHIP-Dependent Degradation of HIF1α in Prostate Cancer Cells

MOLECULAR CANCER THERAPEUTICS

IF5.5

2020-04-02

OAAI

Biswas, Kuntal; Sarkar, Sukumar; Said, Neveen; Brautigan, David L.; Larner, James M.

Functional Alterations in Ciliogenesis-Associated Kinase 1 (CILK1) that Result from Mutations Linked to Juvenile Myoclonic Epilepsy

CELLS

IF5.2

2020-03-12

OAAI

Wang, Eric J.; Gailey, Casey D.; Brautigan, David L.; Fu, Zheng

Protein kinase CK2 phosphorylation of SAPS3 subunit increases PP6 phosphatase activity with Aurora A kinase

BIOCHEMICAL JOURNAL

IF4.3

2020-01-30

OAAI

Heo, Jinho; Larner, James M.; Brautigan, David L.

Deletion of the SAPS1 subunit of protein phosphatase 6 in mice increases radiosensitivity and impairs the cellular DNA damage response 小鼠中蛋白磷酸酶6的SAPS1亚基的缺失会增加放射敏感性并损害细胞DNA损伤反应

DNA REPAIR

IF2.7

2020-01-01

PREAI

Dziegielewski, Jaroslaw; Bonkowska, Magdalena A.; Poniecka, Ewa A.; Heo, Jinho; Du, Kangping; Crittenden, Rowena B.; Bender, Timothy P.; Brautigan, David L.; Larner, James M.

Inactivation of PP2A by a recurrent mutation drives resistance to MEK inhibitors

ONCOGENE

IF7.3

2019-09-20

OAAI

O'Connor, Caitlin M.; Leonard, Daniel; Wiredja, Danica; Avelar, Rita A.; Wang, Zhizhi; Schlatzer, Daniela; Bryson, Benjamin; Tokala, Eesha; Taylor, Sarah E.; Upadhyay, Aditya; Sangodkar, Jaya; Gingras, Anne-Claude; Westermarck, Jukka; Xu, Wenqing; DiFeo, Analisa; Brautigan, David L.; Haider, Shozeb; Jackson, Mark; Narla, Goutham

Ciliogenesis associated kinase 1: targets and functions in various organ systems

FEBS LETTERS

IF3

2019-09-20

OAAI

Fu, Zheng; Gailey, Casey D.; Wang, Eric J.; Brautigan, David L.

研究方向