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R

René Lafont

Sorbonne Université

50H指数
271论文数
8.2K被引数
收录论文 46
发表时间
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Drug Candidate BIO101 for Spinal Muscular Atrophy as Monotherapy or Combined With the Antisense Oligonucleotide ASO-10-27治疗脊髓性肌萎缩症（Spinal Muscular Atrophy）的候选药物BIO101，可单药使用或与反义寡核苷酸ASO-10-27联合使用。
errJournal of Cachexia, Sarcopenia and Muscle
IF0
err2025-10-23
err0
errOAAI
errCynthia Bézier; Steve Cottin; Parvin Nazari Hashemi; Mirella El Khoury; Zoé Clerc; Christine Balducci; Delphine Sapaly; Laure Weill; René Lafont; Stanislas Veillet; Pierre J. Dilda; Frédéric Charbonnier; Mathilde Latil; Olivier Biondi
err分享
err收藏
Efficacy of Oral 20-hydroxyecdysone (20E) in adults with severe COVID-19
errEUROPEAN RESPIRATORY JOURNAL
IF21
err2024-10-30
err0
PREAI
errMorelot-Panzini, Capucine; Snyder, Bryan; Tanni, Suzana; Abrahao, Ludhmila; Valerie, Hajjar; Nair, Pourcher Girish; Lins, Muriel; Devaud, Edouard; Mariani, Jean; Lafont, Rene; Rabut, Sandrine; Ferreira, Claudia; Tourette, Cendrine; Carmelo, Serge; Dioh, Waly; Veillet, Stanislas; Van Maanen, Rob; Maddox, Lee; Plantefeve, Gaetan; Lobo, Suzana
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err收藏
A midgut transcriptional regulatory loop favors an insect host to withstand a bacterial pathogen
errINNOVATION
IF25.7
err2024-09-01
err1
errOAAI
errGuo, Zhaojiang; Zhu, Liuhong; Cheng, Zhouqiang; Dong, Lina; Guo, Le; Bai, Yang; Wu, Qingjun; Wang, Shaoli; Yang, Xin; Xie, Wen; Crickmore, Neil; Zhou, Xuguo; Lafont, Rene; Zhang, Youjun
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err收藏
Efficacy of oral 20-hydroxyecdysone (BIO101), a MAS receptor activator, in adults with severe COVID-19 (COVA): a randomized, placebo-controlled, phase 2/3 trial
errECLINICALMEDICINE
IF10
err2024-02-01
err5
errOAAI
errLobo, Suzana Margareth; Plantefeve, Gaetan; Nair, Girish; Cavalcante, Adilson Joaquim; Moraes, Nara Franzin de; Nunes, Estevao; Barnum, Otis; Stadnik, Claudio Marcel Berdun; Lima, Maria Patelli; Lins, Muriel; Hajjar, Ludhmila Abrahao; Lipinski, Christopher; Islam, Shaheen; Ramos, Fabiano; Simon, Tiago; Martinoti, Jean-Benoit; Guimard, Thomas; Desclaux, Arnaud; Lioger, Bertrand; Neuenschwander, Fernando Carvalho; Paolino, Bruno DeSouza; Amin, Alpesh; Acosta, Samuel Amil; Dilling, Daniel Forde; Cartagena, Edgardo; Snyder, Brian; Devaud, Edouard; Marinho, Ana Karolina Barreto Berselli; Tanni, Suzana; Beato, Patricia Medeiros Milhomem; Dewit, Stephan; Selvan, Vani; Gray, Jeffrey; Fernandez, Ricardo; Pourcher, Valerie; Maddox, Lee; Kay, Richard; Azbekyan, Anait; Chabane, Mounia; Tourette, Cendrine; Esmeraldino, Luis Everton; Dilda, Pierre J.; Lafont, Rene; Mariani, Jean; Camelo, Serge; Rabut, Sandrine; Agus, Samuel; Veillet, Stanislas; Dioh, Waly; van Maanen, Rob; Morelot-Panzini, Capucine
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BIO101 stimulates myoblast differentiation and improves muscle function in adult and old miceBIO101刺激成肌细胞分化并改善成年和老年小鼠的肌肉功能
errJOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE
IF9.1
err2023-12-08
err2
errOAAI
errSerova, Maria; Didry-Barca, Blaise; Deloux, Robin; Foucault, Anne-Sophie; Veillet, Stanislas; Lafont, Rene; Dilda, Pierre J.; Latil, Mathilde
err分享
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A Phase 1 study for safety and pharmacokinetics of BIO101 (20-hydroxyecdysone) in healthy young and older adults
errJOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE
IF9.1
err2023-04-13
err10
errOAAI
errDioh, Waly; Tourette, Cendrine; Del Signore, Susanna; Daudigny, Louiza; Dupont, Philippe; Balducci, Christine; Dilda, Pierre J.; Lafont, Rene; Veillet, Stanislas
err分享
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The Distribution of Phytoecdysteroids among Terrestrial Vascular Plants: A Comparison of Two Databases and Discussion of the Implications for Plant/Insect Interactions and Plant Protection
errPLANTS-BASEL
IF4.1
err2023-02-09
err3
errOAAI
errDinan, Laurence; Lafont, Francoise; Lafont, Rene
err分享
err收藏
20-Hydroxyecdysone activates the protective arm of the RAAS via the MAS receptor
errJOURNAL OF MOLECULAR ENDOCRINOLOGY
IF3.8
err2022-02-01
err26
errOAAI
errLafont, Rene; Serova, Maria; Didry-Barca, Blaise; Raynal, Sophie; Guibout, Louis; Dinan, Laurence; Veillet, Stanislas; Latil, Mathilde; Dioh, Waly; Dilda, Pierre J.
err分享
err收藏
A comparison between virus- versus patients-centred therapeutic attempts to reduce COVID-19 mortality
errEMERGING MICROBES & INFECTIONS
IF7.5
err2021-12-01
err5
errOAAI
errCamelo, Serge; Latil, Mathilde; Agus, Sam; Dioh, Waly; Veillet, Stanislas; Lafont, Rene; Dilda, Pierre J.
err分享
err收藏
Developing new drugs that activate the protective arm of the renin-angiotensin system as a potential treatment for respiratory failure in COVID-19 patients
errDRUG DISCOVERY TODAY
IF7.5
err2021-05-01
err22
errOAAI
errLatil, Mathilde; Camelo, Serge; Veillet, Stanislas; Lafont, Rene; Dilda, Pierre J.
err分享
err收藏
20-Hydroxyecdysone, from Plant Extracts to Clinical Use: Therapeutic Potential for the Treatment of Neuromuscular, Cardio-Metabolic and Respiratory Diseases
errBIOMEDICINES
IF3.9
err2021-04-29
err55
errOAAI
errDinan, Laurence; Dioh, Waly; Veillet, Stanislas; Lafont, Rene
err分享
err收藏
Systemic administration of the di-apocarotenoid norbixin (BIO201) is neuroprotective, preserves photoreceptor function and innibits A2E and lipofuscin accumulation in animal models of age-related macular degeneration and Stargardt disease
errAGING-US
IF3.9
err2020-04-07
err10
errOAAI
errFontaine, Valerie; Monteiro, Elodie; Fournie, Mylene; Brazhnikova, Elena; Boumedine, Thinhinane; Vidal, Cecile; Balducci, Christine; Guibout, Louis; latil, MathilDe; Dilda, Pierre J.; Veillet, Stanislas; Sahel, Jose-Alain; Lafont, Rene; Camelo, Serge
err分享
err收藏
Small-scale analysis of phytoecdysteroids in seeds by HPLC-DAD-MS for the identification and quantification of specific analogues, dereplication and chemotaxonomy
errPHYTOCHEMICAL ANALYSIS
IF2.6
err2020-03-17
err9
PREAI
errDinan, Laurence; Balducci, Christine; Guibout, Louis; Lafont, Rene
err分享
err收藏
Functional Characterization and Signaling Systems of Corazonin and Red Pigment Concentrating Hormone in the Green Shore Crab, Carcinus maenas
errFRONTIERS IN NEUROSCIENCE
IF3.2
err2018-01-15
err35
errOAAI
errAlexander, Jodi L.; Oliphant, Andrew; Wilcockson, David C.; Audsley, Neil; Down, Rachel E.; Lafont, Rene; Webster, Simon G.
err分享
err收藏
Involvement of peroxisome proliferator activator receptors in the photoprotective activity of the di-apo-carotenoid norbixin on RPE cells
errACTA OPHTHALMOLOGICA
IF2.8
err2017-09-07
err1
errOAAI
errFontaine, V.; Monteiro, E.; Fournie, M.; Bonnard, B.; On, S.; Serova, M.; Balducci, C.; Guibout, L.; Sahel, J. A.; Veillet, S.; Dilda, P.; Lafont, R.
err分享
err收藏
20-Hydroxyecdysone protects wheat seedlings (Triticum aestivum L.) against lead stress
errPLANT PHYSIOLOGY AND BIOCHEMISTRY
IF5.7
err2016-01-01
err13
PREAI
errLamhamdi, Mostafa; Lafont, Rene; Rharrabe, Kacem; Sayah, Fouad; Aarab, Ahmed; Bakrim, Ahmed
err分享
err收藏
The minor ecdysteroids from Ajuga turkestanica
errPHYTOCHEMICAL ANALYSIS
IF2.6
err2015-05-08
err23
errOAAI
errGuibout, Louis; Mamadalieva, Nilufar; Balducci, Christine; Girault, Jean-Pierre; Lafont, Rene
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err收藏
The ecdysteroidome of Drosophila: influence of diet and development
errDEVELOPMENT
IF3.6
err2015-01-01
err71
errOAAI
errLavrynenko, Oksana; Rodenfels, Jonathan; Carvalho, Maria; Dye, Natalie A.; Lafont, Rene; Eaton, Suzanne; Shevchenko, Andrej
err分享
err收藏
E- and Z-Isomers of New Phytoecdysteroid Conjugates from French Polynesian Microsorum membranifolium (Polypodiaceae) Fronds
errMOLECULES
IF4.6
err2012-09-28
err10
errOAAI
errHo, Raimana; Girault, Jean-Pierre; Raharivelomanana, Phila; Lafont, Rene
err分享
err收藏
Quinoa Extract Enriched in 20-Hydroxyecdysone Protects Mice From Diet-Induced Obesity and Modulates Adipokines Expression
errOBESITY
IF4.7
err2012-09-06
err77
PREAI
errFoucault, Anne-Sophie; Mathe, Veronique; Lafont, Rene; Even, Patrick; Dioh, Waly; Veillet, Stanislas; Tome, Daniel; Huneau, Jean-Francois; Hermier, Dominique; Quignard-Boulange, Annie
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研究方向

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合作学者
合作期刊
A
Andrej Shevchenko
H 指数: 102 · 论文数: 328
J
José‐Alain Sahel
H 指数: 100 · 论文数: 1.8K
I
Ian D. Wilson
H 指数: 82 · 论文数: 561
B
Bruno Le Bizec
H 指数: 66 · 论文数: 576
P
Peter G. Waterman
H 指数: 64 · 论文数: 611
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