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Geographic and age variations in mutational processes in colorectal cancer 结直肠癌中突变过程的地域和年龄差异 Diaz-Gay, Marcos; dos Santos, Wellington; Moody, Sarah; Kazachkova, Mariya; Abbasi, Ammal; Steele, Christopher D.; Vangara, Raviteja; Senkin, Sergey; Wang, Jingwei; Fitzgerald, Stephen; Bergstrom, Erik N.; Khandekar, Azhar; Otlu, Burcak; Abedi-Ardekani, Behnoush; de Carvalho, Ana Carolina; Cattiaux, Thomas; Penha, Ricardo Cortez Cardoso; Gaborieau, Valerie; Chopard, Priscilia; Carreira, Christine; Cheema, Saamin; Latimer, Calli; Teague, Jon W.; Mukeriya, Anush; Zaridze, David; Cox, Riley; Albert, Monique; Phouthavongsy, Larry; Gallinger, Steven; Malekzadeh, Reza; Niavarani, Ahmadreza; Miladinov, Marko; Eric, Katarina; Milosavljevic, Sasa; Sangrajrang, Suleeporn; Curado, Maria Paula; Aguiar, Samuel; Reis, Monise Tadin; Romagnolo, Luis Gustavo; Guimaraes, Denise Peixoto; Holcatova, Ivana; Kalvach, Jaroslav; Vaccaro, Carlos Alberto; Pinero, Tamara Alejandra; Swiatkowska, Beata; Lissowska, Jolanta; Roszkowska-Purska, Katarzyna; Huertas-Salgado, Antonio; Shibata, Tatsuhiro; Shiba, Satoshi; Sangkhathat, Surasak; Chitapanarux, Taned; Roshandel, Gholamreza; Ashton-Prolla, Patricia; Damin, Daniel C.; de Oliveira, Francine Hehn; Humphreys, Laura; Lawley, Trevor D.; Perdomo, Sandra; Stratton, Michael R.; Brennan, Paul 分享 收藏
Menopausal hormone therapy: assessing associations with breast and colorectal cancers by familial risk 更年期激素治疗: 通过家族风险评估与乳腺癌和结直肠癌的关联 Macinnis, Robert J.; Jenkins, Mark A.; Milne, Roger L.; John, Esther M.; Daly, Mary B.; Andrulis, Irene L.; Colonna, Sarah, V; Phillips, Kelly-Anne; kConFab Investigators, Loic; Le Marchand, Loic; Newcomb, Polly A.; Phipps, Amanda, I; Schmit, Stephanie L.; Macrae, Finlay A.; Buchanan, Daniel D.; Gallinger, Steven; Pai, Rish K.; Samadder, Niloy J.; Giles, Graham G.; Southey, Melissa C.; Hopper, John L.; Terry, Mary Beth 分享 收藏
Minimally invasive determination of pancreatic ductal adenocarcinoma (PDAC) subtype by means of circulating cell-free RNA 通过循环无细胞RNA微创确定胰腺导管腺癌 (PDAC) 亚型 Metzenmacher, Martin; Zaun, Gregor; Trajkovic-Arsic, Marija; Cheung, Phyllis; Reissig, Timm M.; Schuermann, Hendrik; von Neuhoff, Nils; O'Kane, Grainne; Ramotar, Stephanie; Dodd, Anna; Gallinger, Steven; Muckenhuber, Alexander; Knox, Jennifer J.; Kunzmann, Volker; Horn, Peter A.; Hoheisel, Joerg D.; Siveke, Jens T.; Lueong, Smiths S. 分享 收藏
Genomic and transcriptomic characterization of pancreatic cancer patients on the PASS-01 trial O'Kane, Grainne M.; Jang, Gunho; Pugh, Trevor J.; Wilson, Julie; Ramotar, Stephanie; King, Daniel A.; Laheru, Dan; Yu, Ken H.; Perez, Kimberly J.; Habowski, Amber; Tsang, Erica S.; Grant, Robert C.; Aguirre, Andrew J.; Jang, Raymond W-J; Devoe, Craig E.; O'Reilly, Eileen M.; Dodd, Anna; Wolpin, Brian M.; Ye, Xiang Y.; Jaffee, Elizabeth M.; Tuveson, David; Gallinger, Steven; Knox, Jennifer J.; Notta, Faiyaz 分享 收藏
INPP4B promotes PDAC aggressiveness via PIKfyve and TRPML-1-mediated lysosomal exocytosis Saffi, Golam T.; To, Lydia; Kleine, Nicholas; Melo, Che M. P.; Chen, Keyue; Genc, Gizem; Lee, K. C. Daniel; Chow, Jonathan Tak-Sum; Jang, Gun Ho; Gallinger, Steven; Botelho, Roberto J.; Salmena, Leonardo 分享 收藏
In vivo CRISPR screens reveal SCAF1 and USP15 as drivers of pancreatic cancer Martinez, Sebastien; Wu, Shifei; Geuenich, Michael; Malik, Ahmad; Weber, Ramona; Woo, Tristan; Zhang, Amy; Jang, Gun Ho; Dervovic, Dzana; Al-Zahrani, Khalid N.; Tsai, Ricky; Fodil, Nassima; Gros, Philippe; Gallinger, Steven; Neely, G. Gregory; Notta, Faiyaz; Sendoel, Ataman; Campbell, Kieran; Elling, Ulrich; Schramek, Daniel 分享 收藏
Genome-Wide Analysis to Assess if Heavy Alcohol Consumption Modifies the Association between SNPs and Pancreatic Cancer Risk Ni, Zhanmo; Kundu, Prosenjit; Mckean, David F.; Wheeler, William; Albanes, Demetrius; Andreotti, Gabriella; Antwi, Samuel O.; Arslan, Alan A.; Bamlet, William R.; Beane-Freeman, Laura E.; Berndt, Sonja I.; Bracci, Paige M.; Brennan, Paul; Buring, Julie E.; Chanock, Stephen J.; Gallinger, Steven; Gaziano, J. M.; Giles, Graham G.; Giovannucci, Edward L.; Goggins, Michael G.; Goodman, Phyllis J.; Haiman, Christopher A.; Hassan, Manal M.; Holly, Elizabeth A.; Hung, Rayjean J.; Katzke, Verena; Kooperberg, Charles; Kraft, Peter; Lemarchand, Loic; Li, Donghui; Mccullough, Marjorie L.; Milne, Roger L.; Moore, Steven C.; Neale, Rachel E.; Oberg, Ann L.; Patel, Alpa V.; Peters, Ulrike; Rabe, Kari G.; Risch, Harvey A.; Shu, Xiao-Ou; Smith-Byrne, Karl; Visvanathan, Kala; Wactawski-Wende, Jean; White, Emily; Wolpin, Brian M.; Yu, Herbert; Zeleniuch-Jacquotte, Anne; Zheng, Wei; Zhong, Jun; Amundadottir, Laufey T.; Stolzenberg-Solomon, Rachael Z.; Klein, Alison P. 分享 收藏
NeoPancONE: Feasibility of completing a neoadjuvant multicentre phase II study in resectable pancreatic ductal adenocarcinoma (r-PDAC), treated with modified FOLFIRINOX (mFFX) McLaughlin, R. A.; Coyne, Z.; Jonker, D.; Karanicolas, P.; Hakim, S.; Welch, S.; Renouf, D. J.; Bertens, K.; Moulton, C-A.; Raphael, M.; Jayaraman, S.; Moore, M.; Elimova, E.; Coburn, N.; Abou-Khalil, J.; Khalili, K.; Fischer, S. E.; Dodd, A.; Gallinger, S.; Knox, J. J. 分享 收藏
Fine-mapping analysis including over 254,000 East Asian and European descendants identifies 136 putative colorectal cancer susceptibility genes 包括254,000多名东亚和欧洲后代的精细图谱分析确定了136个推定的结直肠癌易感基因 Chen, Zhishan; Guo, Xingyi; Tao, Ran; Huyghe, Jeroen R.; Law, Philip J.; Fernandez-Rozadilla, Ceres; Ping, Jie; Jia, Guochong; Long, Jirong; Li, Chao; Shen, Quanhu; Xie, Yuhan; Timofeeva, Maria N.; Thomas, Minta; Schmit, Stephanie L.; Diez-Obrero, Virginia; Devall, Matthew; Moratalla-Navarro, Ferran; Fernandez-Tajes, Juan; Palles, Claire; Sherwood, Kitty; Briggs, Sarah E. W.; Svinti, Victoria; Donnelly, Kevin; Farrington, Susan M.; Blackmur, James; Vaughan-Shaw, Peter G.; Shu, Xiao-Ou; Lu, Yingchang; Broderick, Peter; Studd, James; Harrison, Tabitha A.; Conti, David V.; Schumacher, Fredrick R.; Melas, Marilena; Rennert, Gad; Obon-Santacana, Mireia; Martin-Sanchez, Vicente; Oh, Jae Hwan; Kim, Jeongseon; Jee, Sun Ha; Jung, Keum Ji; Kweon, Sun-Seog; Shin, Min-Ho; Shin, Aesun; Ahn, Yoon-Ok; Kim, Dong-Hyun; Oze, Isao; Wen, Wanqing; Matsuo, Keitaro; Matsuda, Koichi; Tanikawa, Chizu; Ren, Zefang; Gao, Yu-Tang; Jia, Wei-Hua; Hopper, John L.; Jenkins, Mark A.; Win, Aung Ko; Pai, Rish K.; Figueiredo, Jane C.; Haile, Robert W.; Gallinger, Steven; Woods, Michael O.; Newcomb, Polly A.; Duggan, David; Cheadle, Jeremy P.; Kaplan, Richard; Kerr, Rachel; Kerr, David; Kirac, Iva; Bohm, Jan; Mecklin, Jukka-Pekka; Jousilahti, Pekka; Knekt, Paul; Aaltonen, Lauri A.; Rissanen, Harri; Pukkala, Eero; Eriksson, Johan G.; Cajuso, Tatiana; Hanninen, Ulrika; Kondelin, Johanna; Palin, Kimmo; Tanskanen, Tomas; Renkonen-Sinisalo, Laura; Mannisto, Satu; Albanes, Demetrius; Weinstein, Stephanie J.; Ruiz-Narvaez, Edward; Palmer, Julie R.; Buchanan, Daniel D.; Platz, Elizabeth A.; Visvanathan, Kala; Ulrich, Cornelia M.; Siegel, Erin; Brezina, Stefanie; Gsur, Andrea; Campbell, Peter T.; Chang-Claude, Jenny; Hoffmeister, Michael; Brenner, Hermann; Slattery, Martha L.; Potter, John D.; Tsilidis, Kostas K.; Schulze, Matthias B.; Gunter, Marc J.; Murphy, Neil; Castells, Antoni; Castellvi-Bel, Sergi; Moreira, Leticia; Arndt, Volker; Shcherbina, Anna; Bishop, D. Timothy; Giles, Graham G.; Southey, Melissa C.; Idos, Gregory E.; McDonnell, Kevin J.; Abu-Ful, Zomoroda; Greenson, Joel K.; Shulman, Katerina; Lejbkowicz, Flavio; Offit, Kenneth; Su, Yu-Ru; Steinfelder, Robert; Keku, Temitope O.; van Guelpen, Bethany; Hudson, Thomas J.; Hampel, Heather; Pearlman, Rachel; Berndt, Sonja I.; Hayes, Richard B.; Martinez, Marie Elena; Thomas, Sushma S.; Pharoah, Paul D. P.; Larsson, Susanna C.; Yen, Yun; Lenz, Heinz-Josef; White, Emily; Li, Li; Doheny, Kimberly F.; Pugh, Elizabeth; Shelford, Tameka; Chan, Andrew T.; Cruz-Correa, Marcia; Lindblom, Annika; Hunter, David J.; Joshi, Amit D.; Schafmayer, Clemens; Scacheri, Peter C.; Kundaje, Anshul; Schoen, Robert E.; Hampe, Jochen; Stadler, Zsofia K.; Vodicka, Pavel; Vodickova, Ludmila; Vymetalkova, Veronika; Edlund, Christopher K.; Gauderman, W. James; Shibata, David; Toland, Amanda; Markowitz, Sanford; Kim, Andre; Chanock, Stephen J.; van Duijnhoven, Franzel; Feskens, Edith J. M.; Sakoda, Lori C.; Gago-Dominguez, Manuela; Wolk, Alicja; Pardini, Barbara; FitzGerald, Liesel M.; Lee, Soo Chin; Ogino, Shuji; Bien, Stephanie A.; Kooperberg, Charles; Li, Christopher I.; Lin, Yi; Prentice, Ross; Qu, Conghui; Bezieau, Stephane; Yamaji, Taiki; Sawada, Norie; Iwasaki, Motoki; Le Marchand, Loic; Wu, Anna H.; Qu, Chenxu; McNeil, Caroline E.; Coetzee, Gerhard; Hayward, Caroline; Deary, Ian J.; Harris, Sarah E.; Theodoratou, Evropi; Reid, Stuart; Walker, Marion; Ooi, Li Yin; Lau, Ken S.; Zhao, Hongyu; Hsu, Li; Cai, Qiuyin; Dunlop, Malcolm G.; Gruber, Stephen B.; Houlston, Richard S.; Moreno, Victor; Casey, Graham; Peters, Ulrike; Tomlinson, Ian; Zheng, Wei 分享 收藏
Genetic risk impacts the association of menopausal hormone therapy with colorectal cancer risk 遗传风险影响更年期激素治疗与结直肠癌风险的关系 Tian, Yu; Lin, Yi; Qu, Conghui; Arndt, Volker; Baurley, James W.; Berndt, Sonja I.; Bien, Stephanie A.; Bishop, D. Timothy; Brenner, Hermann; Buchanan, Daniel D.; Budiarto, Arif; Campbell, Peter T.; Carreras-Torres, Robert; Casey, Graham; Chan, Andrew T.; Chen, Rui; Chen, Xuechen; Conti, David V.; Diez-Obrero, Virginia; Dimou, Niki; Drew, David A.; Figueiredo, Jane C.; Gallinger, Steven; Giles, Graham G.; Gruber, Stephen B.; Gunter, Marc J.; Harlid, Sophia; Harrison, Tabitha A.; Hidaka, Akihisa; Hoffmeister, Michael; Huyghe, Jeroen R.; Jenkins, Mark A.; Jordahl, Kristina M.; Joshi, Amit D.; Keku, Temitope O.; Kawaguchi, Eric; Kim, Andre E.; Kundaje, Anshul; Larsson, Susanna C.; Marchand, Loic Le; Lewinger, Juan Pablo; Li, Li; Moreno, Victor; Morrison, John; Murphy, Neil; Nan, Hongmei; Nassir, Rami; Newcomb, Polly A.; Obon-Santacana, Mireia; Ogino, Shuji; Ose, Jennifer; Pardamean, Bens; Pellatt, Andrew J.; Peoples, Anita R.; Platz, Elizabeth A.; Potter, John D.; Prentice, Ross L.; Rennert, Gad; Ruiz-Narvaez, Edward A.; Sakoda, Lori C.; Schoen, Robert E.; Shcherbina, Anna; Stern, Mariana C.; Su, Yu-Ru; Thibodeau, Stephen N.; Thomas, Duncan C.; Tsilidis, Konstantinos K.; van Duijnhoven, Franzel J. B.; Van Guelpen, Bethany; Visvanathan, Kala; White, Emily; Wolk, Alicja; Woods, Michael O.; Wu, Anna H.; Peters, Ulrike; Gauderman, W. James; Hsu, Li; Chang-Claude, Jenny 分享 收藏
Genetic modifiers of KRAS-mutant colorectal cancer Tjader, Nijole P.; Ramroop, Johnny; Gandhi, Tanish; Campbell, Peter T.; Chan, Andrew T.; Gallinger, Steven; Giles, Graham G.; Gunter, Marc J.; Harrison, Tabitha A.; Hoffmeister, Michael; Newcomb, Polly A.; Ogino, Shuji; Phipps, Amanda I.; Qu, Conghui; Schoen, Robert E.; Pellatt, Andrew; Woods, Michael O.; Van Guelpen, Bethany; Stevens, Patrick; Hampel, Heather; Peters, Ulrike; McElroy, Joseph P.; Toland, Amanda E. 分享 收藏
Clinical and phenotypic consequences of HLA mediated antigen presentation deficiency in pancreatic adenocarcinoma at bulk and single-cell resolution Geuenich, Michael J.; Gruenwald, Barbara; O'Kane, Grainne; Yu, Chengxin; Ju, Tan Tiak; Zhang, Amy; Hamza, Oumaima; Jang, Gun Ho; Notta, Faiyaz; Gallinger, Steven; Campbell, Kieran R. 分享 收藏
Cytidine deaminases APOBEC3C and APOBEC3D promote DNA replication stress resistance in pancreatic cancer cells 胞苷脱氨酶APOBEC3C和APOBEC3D促进胰腺癌细胞的DNA复制应激抵抗 Ubhi, Tajinder; Zaslaver, Olga; Quaile, Andrew T.; Plenker, Dennis; Cao, Pinjiang; Pham, Nhu-An; Bekesi, Angela; Jang, Gun-Ho; O'Kane, Grainne M.; Notta, Faiyaz; Moffat, Jason; Wilson, Julie M.; Gallinger, Steven; Vertessy, Beata G.; Tuveson, David A.; Rost, Hannes L.; Brown, Grant W. 分享 收藏
Body size and risk of colorectal cancer molecular defined subtypes and pathways: Mendelian randomization analyses 结直肠癌的体型和风险分子定义的亚型和途径: 孟德尔随机化分析 Papadimitriou, Nikos; Qu, Conghui; Harrison, Tabitha A.; Bever, Alaina M.; Martin, Richard M.; Tsilidis, Konstantino K.; Newcomb, Polly A.; Thibadeau, Stephen N.; Newton, Christina C.; Um, Caroline Y.; Obon-Santacana, Mireia; Moreno, Victor; Brenner, Hermann; Mandic, Marko; Chang-Claude, Jenny; Hoffmeister, Michael; Pellatt, Andrew J.; Schoen, Robert E.; Harlid, Sophia; Ogino, Shuji; Ugai, Tomotaka; Buchanan, Daniel D.; Lynch, Brigid M.; Gruber, Stephen B.; Cao, Yin; Hsu, Li; Huyghe, Jeroen R.; Lin, Yi; Steinfelder, Robert S.; Sun, Wei; Van Guelpen, Bethany; Zaidi, Syed H.; Toland, Amanda E.; Berndt, Sonja I.; Huang, Wen-Yi; Aglago, Elom K.; Drew, David A.; French, Amy J.; Georgeson, Peter; Giannakis, Marios; Hullar, Meredith; Nowak, Johnathan A.; Thomas, Claire E.; LeMarchand, Loic; Cheng, Iona; Gallinger, Steven; Jenkins, Mark A.; Gunter, Marc J.; Campbell, Peter T.; Peters, Ulrike; Song, Mingyang; Phipps, Amanda I.; Murphya, Neil 分享 收藏
Characterizing the burden of biliary tract cancers across 28 hospitals in Ontario, Canada Choi, Woo Jin; Roberts, Surain; Verma, Amol; Razak, Fahad; O'Kane, Grainne M.; Gallinger, Steven; Hirschfield, Gideon; Hansen, Bettina; Sapisochin, Gonzalo 分享 收藏
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Performance evaluation of a North American center using the established global benchmark for laparoscopic liver resections: A retrospective study Choi, Woo Jin; Babakhani, Shiva; Claasen, Marco P. A. W.; Castelo, Matthew; Bucur, Roxana; Gaviria, Felipe; Jones, Owen; Shwaartz, Chaya; McCluskey, Stuart A.; McGilvray, Ian; Gallinger, Steven; Moulton, Carol-Anne; Reichman, Trevor; Cleary, Sean; Sapisochin, Gonzalo 分享 收藏
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