Nico Vermeulen - Publications, H-index & Citations

Nico Vermeulen

Leiden University

64H指数

856论文数

2.4W被引数

收录论文 60

发表时间

The EU chemicals strategy for sustainability: in support of the BfR position

ARCHIVES OF TOXICOLOGY

IF6.9

2021-08-07

OAAI

Barile, Frank A.; Berry, Colin; Blaauboer, Bas; Boobis, Alan; Bolt, Herrmann M.; Borgert, Christopher; Dekant, Wolfgang; Dietrich, Daniel; Domingo, Jose L.; Galli, Corrado L.; Gori, Gio Batta; Greim, Helmut; Hengstler, Jan G.; Heslop-Harrison, Pat; Kacew, Sam; Marquardt, Hans; Mally, Angela; Pelkonen, Olavi; Savolainen, Kai; Testai, Emanuela; Tsatsakis, Aristides; Vermeulen, Nico P.

Human exposure to synthetic endocrine disrupting chemicals (S-EDCs) is generally negligible as compared to natural compounds with higher or comparable endocrine activity. How to evaluate the risk of the S-EDCs?

ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

IF4.2

2020-08-01

OAAI

Autrup, Herman; Barile, Frank A.; Berry, Sir Colin; Blaauboer, Bas J.; Boobis, Alan; Bolt, Herrmann; Borgert, Christopher J.; Dekant, Wolfgang; Dietrich, Daniel; Domingo, Jose L.; Gori, Gio Batta; Greim, Helmut; Hengstler, Jan; Kacew, Sam; Marquardt, Hans; Pelkonen, Olavi; Savolainen, Kai; Heslop-Harrison, Pat; Vermeulen, Nico P.

FOOD AND CHEMICAL TOXICOLOGY

IF3.5

2020-08-01

PREAI

Autrup, Herman; Barile, Frank A.; Berry, Sir Colin; Blaauboer, Bas J.; Boobis, Alan; Bolt, Herrmann; Hengstler, Jan; Borgert, Christopher J.; Dekant, Wolfgang; Dietrich, Daniel; Domingo, Jose L.; Gori, Gio Batta; Greim, Helmut; Kacew, Sam; Marquardt, Hans; Pelkonen, Olavi; Savolainen, Kai; Heslop-Harrison, Pat; Vermeulen, Nico P.

Human exposure to synthetic endocrine disrupting chemicals (S-EDCs) is generally negligible as compared to natural compounds with higher or comparable endocrine activity: how to evaluate the risk of the S-EDCs?

ARCHIVES OF TOXICOLOGY

IF6.9

2020-06-08

OAAI

Human multidrug resistance protein 4 (MRP4) is a cellular efflux transporter for paracetamol glutathione and cysteine conjugates

ARCHIVES OF TOXICOLOGY

IF6.9

2020-05-29

OAAI

Koenderink, Jan B.; van den Heuvel, Jeroen J. M. W.; Bilos, Ab; Vredenburg, Galvin; Vermeulen, Nico P. E.; Russel, Frans G. M.

A Comparative Linear Interaction Energy and MM/PBSA Study on SIRT1-Ligand Binding Free Energy Calculation

JOURNAL OF CHEMICAL INFORMATION AND MODELING

IF5.3

2019-08-28

OAAI

Rifai, Eko Aditya; van Dijk, Marc; Vermeulen, Nico P. E.; Yanuar, Arry; Geerke, Daan P.

Characterization of kinetics of human cytochrome P450s involved in bioactivation of flucloxacillin: inhibition of CYP3A-catalysed hydroxylation by sulfaphenazole

BRITISH JOURNAL OF PHARMACOLOGY

IF7.7

2018-12-26

OAAI

Dekker, Stefan J.; Dohmen, Floor; Vermeulen, Nico P. E.; Commandeur, Jan N. M.

Linking cytochrome P450 enzymes from Mycobacterium tuberculosis to their cognate ferredoxin partners

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

IF4.3

2018-08-22

OAAI

Ugalde, Sandra Ortega; de Koning, Coen P.; Wallraven, Kerstin; Bruyneel, Ben; Vermeulen, Nico P. E.; Grossmann, Tom N.; Bitter, Wilbert; Commandeur, Jan N. M.; Vos, J. Chris

Acetaminophen reduces the protein levels of high affinity amino acid permeases and causes tryptophan depletion

AMINO ACIDS

IF2.4

2018-07-05

OAAI

Huseinovic, Angelina; Dekker, Stefan J.; Boogaard, Bob; Vermeulen, Nico. P. E.; Kooter, Jan M.; Vos, J. Chris

A combined computational and experimental study on selective flucloxacillin hydroxylation by cytochrome P450 BM3 variants

JOURNAL OF INORGANIC BIOCHEMISTRY

IF3.2

2018-07-01

OAAI

Luirink, Rosa A.; Dekker, Stefan J.; Capoferri, Luigi; Janssen, Laura F. H.; Kuiper, Cynthia L.; Ari, Mehmet E.; Vermeulen, Nico P. E.; Vos, J. Chris; Commandeur, Jan N. M.; Geerke, Daan P.

High-performance liquid chromatography-based assay for glutathione transferase theta 2 activity: Application to characterize interindividual variability in human liver fractions

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

IF3.1

2018-07-01

OAAI

Zhang, Yongjie; Wijaya, Lukas; Dekker, Stefan J.; Vermeulen, Nico P. E.; Commandeur, Jan N. M.

Engineering a self-sufficient Mycobacterium tuberculosis CYP130 by gene fusion with the reductase-domain of CYP102A1 from Bacillus megaterium

JOURNAL OF INORGANIC BIOCHEMISTRY

IF3.2

2018-03-01

OAAI

Ugalde, Sandra Ortega; Luirink, Rosa A.; Geerke, Daan P.; Vermeulen, Nico P. E.; Bitter, Wilbert; Commandeur, Jan N. M.

Reduction and Scavenging of Chemically Reactive Drug Metabolites by NAD(P)H:Quinone Oxidoreductase 1 and NRH:Quinone Oxidoreductase 2 and Variability in Hepatic Concentrations

CHEMICAL RESEARCH IN TOXICOLOGY

IF3.8

2018-01-11

OAAI

den Braver-Sewradj, Shalenie P.; den Braver, Michiel W.; Toorneman, Robin M.; van Leeuwen, Stephanie; Zhang, Yongjie; Dekker, Stefan J.; Vermeulen, Nico P. E.; Commandeur, Jan N. M.; Vos, J. Chris

eTOX ALLIES: an automated pipeLine for linear interaction energy-based simulations

JOURNAL OF CHEMINFORMATICS

IF5.7

2017-11-21

OAAI

Capoferri, Luigi; van Dijk, Marc; Rustenburg, Arien S.; Wassenaar, Tsjerk A.; Kooi, Derk P.; Rifai, Eko A.; Vermeulen, Nico P. E.; Geerke, Daan P.

Direct comparison of UDP-glucuronosyltransferase and cytochrome P450 activities in human liver microsomes, plated and suspended primary human hepatocytes from five liver donors 直接比较来自五个肝脏供体的人肝微粒体，平板和悬浮的原代人肝细胞中的UDP-葡萄糖醛酸基转移酶和细胞色素P450活性

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

IF4.7

2017-11-01

OAAI

den Braver-Sewradj, Shalenie P.; den Braver, Michiel W.; Baze, Audrey; Decorde, Joachim; Fonsi, Massimiliano; Bachellier, Philippe; Vermeulen, Nico P. E.; Commandeur, Jan N. M.; Richert, Lysiane; Vos, J. Chris

Binding free energy predictions of farnesoid X receptor (FXR) agonists using a linear interaction energy (LIE) approach with reliability estimation: application to the D3R Grand Challenge 2

JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

IF3.1

2017-09-09

OAAI

Rifai, Eko Aditya; van Dijk, Marc; Vermeulen, Nico P. E.; Geerke, Daan P.

Comprehensive and Automated Linear Interaction Energy Based Binding-Affinity Prediction for Multifarious Cytochrome P450 Aromatase Inhibitors

JOURNAL OF CHEMICAL INFORMATION AND MODELING

IF5.3

2017-08-23

OAAI

van Dijk, Marc; ter Laakt, Antonius M.; Wichard, Jorg D.; Capoferri, Luigi; Vermeulen, Nico P. E.; Geerke, Daan P.

Different Reactive Metabolites of Nevirapine Require Distinct Glutathione S-Transferase Isoforms for Bioinactivation

CHEMICAL RESEARCH IN TOXICOLOGY

IF3.8

2016-11-28

PREAI

Dekker, Stefan J.; Zhang, Yongjie; Vos, J. Chris; Vermeulen, Nico P. E.; Commandeur, Jan N. M.

Characterization of human cytochrome P450 mediated bioactivation of amodiaquine and its major metabolite N-desethylamodiaquine

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

IF3

2016-11-16

OAAI

Zhang, Yongjie; Vermeulen, Nico P. E.; Commandeur, Jan N. M.

Evidence-based selection of training compounds for use in the mechanism-based integrated prediction of drug-induced liver injury in man

ARCHIVES OF TOXICOLOGY

IF6.9

2016-09-22

OAAI

Dragovic, Sanja; Vermeulen, Nico P. E.; Gerets, Helga H.; Hewitt, Philip G.; Ingelman-Sundberg, Magnus; Park, B. Kevin; Juhila, Satu; Snoeys, Jan; Weaver, Richard J.

研究方向