Cyrus Agarabi - Publications, H-index & Citations

Cyrus Agarabi

us food & drug administration (fda)

21H指数

65论文数

1.5K被引数

收录论文 25

发表时间

Defining Golden Batches in Biomanufacturing Processes From Internal Metabolic Activity to Detect Process Changes That May Affect Product Quality

BIOTECHNOLOGY AND BIOENGINEERING

IF3.6

2024-10-27

PREAI

Bush, Xin; Fratz-Berilla, Erica J.; Kohnhorst, Casey L.; King, Roberta; Agarabi, Cyrus; Powers, David N.; Trunfio, Nicholas

A chemoenzymatic method for simultaneous profiling N- and O-glycans on glycoproteins using one-pot format

CELL REPORTS METHODS

IF4.5

2024-08-01

OAAI

Ortega-Rodriguez, Uriel; Bettinger, John Q.; Zou, Guozhang; Falkowski, Vincent M.; Lehtimaki, Mari; Matthews, Alicia M.; Biel, Thomas G.; Pritts, Jordan D.; Wu, Wells W.; Shen, Rong-Fong; Agarabi, Cyrus; Rao, V. Ashutosh; Xie, Hang; Ju, Tongzhong

Model acetylcholinesterase-Fc fusion glycoprotein biotechnology system for the manufacture of an organophosphorus toxicant bioscavenging countermeasure

BIOENGINEERING & TRANSLATIONAL MEDICINE

IF5.7

2024-04-25

OAAI

Biel, Thomas G.; Faison, Talia; Matthews, Alicia M.; Ortega-Rodriguez, Uriel; Falkowski, Vincent M.; Meek, Edward; Bush, Xin; Flores, Matthew; Johnson, Sarah; Wu, Wells W.; Lehtimaki, Mari; Shen, Rong-Fong; Agarabi, Cyrus; Rao, V. Ashutosh; Chambers, Janice E.; Ju, Tongzhong

Evaluation of single-use optical and electrochemical pH sensors in upstream bioprocessing

HELIYON

IF3.6

2024-02-01

OAAI

Fratz-Berilla, Erica J.; Kohnhorst, Casey; Trunfio, Nicholas; Bush, Xin; Gyorgypal, Aron; Agarabi, Cyrus

Failure Mode Identification of Insulin Drug Products-Impact of Relevant Stress Conditions on the Quality of the Drug

JOURNAL OF PHARMACEUTICAL SCIENCES

IF3.8

2022-09-01

OAAI

Kim, Minkyung; Chikkaveeraiah, Bhaskara Vijaya; Maniar, Drishti; Roelofs, Brian; Ramaswamy, Muthukumar; Abbineni, Gopal; Agarabi, Cyrus; Bhirde, Ashwinkumar

High Performance Size Exclusion Chromatography and High-Throughput Dynamic Light Scattering as Orthogonal Methods to Screen for Aggregation and Stability of Monoclonal Antibody Drug Products

JOURNAL OF PHARMACEUTICAL SCIENCES

IF3.8

2020-11-01

PREAI

Bhirde, Ashwinkumar; Chikkaveeraiah, Bhaskara Vijaya; Venna, Ramesh; Carley, Rachel; Brorson, Kurt; Agarabi, Cyrus

Impacts on product quality attributes of monoclonal antibodies produced in CHO cell bioreactor cultures during intentional mycoplasma contamination events

BIOTECHNOLOGY AND BIOENGINEERING

IF3.6

2020-06-04

OAAI

Fratz-Berilla, Erica J.; Angart, Phillip; Graham, Ryan J.; Powers, David N.; Mohammad, Adil; Kohnhorst, Casey; Faison, Talia; Velugula-Yellela, Sai Rashmika; Trunfio, Nicholas; Agarabi, Cyrus

A high-resolution measurement of nucleotide sugars by using ion-pair reverse chromatography and tandem columns

ANALYTICAL AND BIOANALYTICAL CHEMISTRY

IF3.8

2020-04-16

PREAI

Sha, Sha; Handelman, Garry; Agarabi, Cyrus; Yoon, Seongkyu

The ELISA Detectability and Potency of Pegfilgrastim Decrease in Physiological Conditions: Key Roles for Aggregation and Individual Variability

SCIENTIFIC REPORTS

IF3.9

2020-02-12

OAAI

Xie, Tao; Fang, Hui; Ouyang, Weiming; Angart, Phillip; Chiang, Meng-Jung; Bhirde, Ashwinkumar A.; Sheikh, Faruk; Lynch, Patrick; Shah, Ankit B.; Patil, Sharadrao M.; Chen, Kang; Shen, Meiyu; Agarabi, Cyrus; Donnelly, Raymond P.; Brorson, Kurt; Schrieber, Sarah J.; Howard, Kristina E.; Rogstad, Sarah M.; Frucht, David M.

Impacts of intentional mycoplasma contamination on CHO cell bioreactor cultures 故意支原体污染对CHO细胞生物反应器培养物的影响

BIOTECHNOLOGY AND BIOENGINEERING

IF3.6

2019-09-11

OAAI

Fratz-Berilla, Erica J.; Faison, Talia; Kohnhorst, Casey L.; Velugula-Yellela, Sai Rashmika; Powers, David N.; Brorson, Kurt; Agarabi, Cyrus

The Current Scientific and Regulatory Landscape in Advancing Integrated Continuous Biopharmaceutical Manufacturing

TRENDS IN BIOTECHNOLOGY

IF14.9

2019-03-01

114

PREAI

Fisher, Adam C.; Kamga, Mark-Henry; Agarabi, Cyrus; Brorson, Kurt; Lee, Sau L.; Yoon, Seongkyu

An ICP-MS platform for metal content assessment of cell culture media and evaluation of spikes in metal concentration on the quality of an IgG3:κ monoclonal antibody during production

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

IF3.1

2019-01-01

PREAI

Mohammad, Adil; Agarabi, Cyrus; Rogstad, Sarah; DiCioccio, Elizabeth; Brorson, Kurt; Ashraf, Muhammad; Faustino, Patrick J.; Madhavarao, Chikkathur N.

Comprehensive analysis of N-glycans in IgG purified from ferrets with or without influenza A virus infection

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2018-12-01

OAAI

Zou, Guozhang; Kosikova, Martina; Kim, Su-Ryun; Kotian, Shweta; Wu, Wells W.; Shen, Rongfong; Powers, David N.; Agarabi, Cyrus; Xie, Hang; Ju, Tongzhong

A design space exploration for control of Critical Quality Attributes of mAb

INTERNATIONAL JOURNAL OF PHARMACEUTICS

IF5.2

2016-10-01

OAAI

Bhatia, Hemlata; Read, Erik; Agarabi, Cyrus; Brorson, Kurt; Lute, Scott; Yoon, Seongkyu

N-Glycosylation Design and Control of Therapeutic Monoclonal Antibodies

TRENDS IN BIOTECHNOLOGY

IF14.9

2016-10-01

139

PREAI

Sha, Sha; Agarabi, Cyrus; Brorson, Kurt; Lee, Dong-Yup; Yoon, Seongkyu

Real time monitoring of bioreactor mAb IgG3 cell culture process dynamics via Fourier transform infrared spectroscopy: Implications for enabling cell culture process analytical technology

FRONTIERS OF CHEMICAL SCIENCE AND ENGINEERING

IF4.5

2015-10-13

PREAI

Wu, Huiquan; Read, Erik; White, Maury; Chavez, Brittany; Brorson, Kurt; Agarabi, Cyrus; Khan, Mansoor

Product and process understanding to relate the effect of freezing method on glycation and aggregation of lyophilized monoclonal antibody formulations

INTERNATIONAL JOURNAL OF PHARMACEUTICS

IF5.2

2015-07-01

PREAI

Awotwe-Otoo, David; Agarabi, Cyrus; Read, Erik K.; Lute, Scott; Brorson, Kurt A.; Khan, Mansoor A.

Bioreactor Process Parameter Screening Utilizing a Plackett-Burman Design for a Model Monoclonal Antibody

JOURNAL OF PHARMACEUTICAL SCIENCES

IF3.8

2015-06-01

OAAI

Agarabi, Cyrus D.; Schiel, John E.; Lute, Scott C.; Chavez, Brittany K.; Boyne, Michael T., II; Brorson, Kurt A.; Khan, Mansoor A.; Read, Erik K.

An Integrated Process Analytical Technology (PAT) Approach to Monitoring the Effect of Supercooling on Lyophilization Product and Process Parameters of Model Monoclonal Antibody Formulations 一种集成过程分析技术 (PAT) 方法，用于监测过冷对模型单克隆抗体制剂的冻干产品和过程参数的影响

JOURNAL OF PHARMACEUTICAL SCIENCES

IF3.8

2014-07-01

PREAI

Awotwe-Otoo, David; Agarabi, Cyrus; Khan, Mansoor A.

Evaluation of butyrate-induced production of a mannose-6-phosphorylated therapeutic enzyme using parallel bioreactors

BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY

IF2.7

2014-02-20

OAAI

Madhavarao, Chikkathur N.; Agarabi, Cyrus D.; Wong, Lily; Mueller-Loennies, Sven; Braulke, Thomas; Khan, Mansoor; Anderson, Howard; Johnson, Gibbes R.

研究方向