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Clonal analysis of fetal hematopoietic stem/progenitor cells reveals how post-transplantation capabilities are distributed Stonehouse, Olivia J.; Biben, Christine; Weber, Tom S.; Garnham, Alexandra; Fennell, Katie A.; Farley, Alison; Terreaux, Antoine F.; Alexander, Warren S.; Dawson, Mark A.; Naik, Shalin H.; Taoudi, Samir 分享 收藏
The histone acetyltransferase KAT6B is required for hematopoietic stem cell development and function Bergamasco, Maria I.; Ranathunga, Nishika; Abeysekera, Waruni; Li-Wai-Suen, Connie S. N.; Garnham, Alexandra L.; Willis, Simon N.; Mcrae, Helen M.; Yang, Yuqing; D'Amico, Angela; Di Rago, Ladina; Wilcox, Stephen; Nutt, Stephen L.; Alexander, Warren S.; Smyth, Gordon K.; Voss, Anne K.; Thomas, Tim 分享 收藏
Differential in vivo roles of Mpl cytoplasmic tyrosine residues in murine hematopoiesis and myeloproliferative disease Behrens, Kira; Kauppi, Maria; Viney, Elizabeth M.; Kueh, Andrew J.; Hyland, Craig D.; Willson, Tracy A.; Salleh, Liam; de Graaf, Carolyn A.; Babon, Jeffrey J.; Herold, Marco J.; Nicola, Nicos A.; Alexander, Warren S. 分享 收藏
ERG and c-MYC regulate a critical gene network in BCR::ABL1-driven B cell acute lymphoblastic leukemia Behrens, Kira; Brajanovski, Natalie; Xu, Zhen; Viney, Elizabeth M.; Dirago, Ladina; Hediyeh-Zadeh, Soroor; Davis, Melissa J.; Pearson, Richard B.; Sanij, Elaine; Alexander, Warren S.; Ng, Ashley P. 分享 收藏
CIS is a potent checkpoint in NK cell-mediated tumor immunity (vol 17, pg 816, 2016) Delconte, Rebecca B.; Kolesnik, Tatiana B.; Dagley, Laura F.; Rautela, Jai; Shi, Wei; Putz, Eva M.; Stannard, Kimberley; Zhang, Jian-Guo; Teh, Charis; Firth, Matt; Ushiki, Takashi; Andoniou, Christopher E.; Degli-Esposti, Mariapia A.; Sharp, Phillip P.; Sanvitale, Caroline E.; Infusini, Giuseppe; Liau, Nicholas P. D.; Linossi, Edmond M.; Burns, Christopher J.; Carotta, Sebastian; Gray, Daniel H. D.; Seillet, Cyril; Hutchinson, Dana S.; Belz, Gabrielle T.; Webb, Andrew I.; Alexander, Warren S.; Li, Shawn S.; Bullock, Alex N.; Babon, Jeffrey J.; Smyth, Mark J.; Nicholson, Sandra E.; Huntington, Nicholas D. 分享 收藏
The SOCS1 KIR and SH2 domain are both required for suppression of cytokine signaling in vivo SOCS1 KIR和SH2结构域都是体内抑制细胞因子信号传导所必需的 Doggett, Karen; Keating, Narelle; Dehkhoda, Farhad; Bidgood, Grace M.; Guzman, Lizeth G. Meza; Leong, Evelyn; Kueh, Andrew; Nicola, Nicos A.; Kershaw, Nadia J.; Babon, Jeffrey J.; Alexander, Warren S.; Nicholson, Sandra E. 分享 收藏
Proinflammatory microenvironment promotes lymphoma progression in mice with high megakaryocyte and TPO levels Au, Amanda E.; Corbin, Jason; Lebois, Marion; Gangatirkar, Pradnya; Yassinson, Fatme; Hyslop, Stephanie R.; Cannon, Ping; Mason, Kylie D.; Li-Wai-Suen, Connie S. N.; Garnham, Alexandra L.; Moujalled, Diane; Cimmino, Luisa; Alexander, Warren S.; Josefsson, Emma C. 分享 收藏
Agm1/Pgm-3-mediated sugar nucleotide synthesis is essential for hematopoiesis and development Agm1/Pgm-3-mediated糖核苷酸合成对造血和发育至关重要 Greig, Kylle T.; Antonchuk, Jennifer; Metcalf, Donald; Morgan, Phillip O.; Krebs, Danielle L.; Zhang, Jian-Guo; Hacking, Douglas F.; Bode, Lars; Robb, Lorraine; Kranz, Christian; de Graaf, Carolyn; Bahlo, Melanie; Nicola, Nicos A.; Nutt, Stephen L.; Freeze, Hudson H.; Alexander, Warren S.; Hilton, Douglas J.; Kile, Benjamin T. 分享 收藏
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SOCS-6 binds to insulin receptor substrate 4, and mice lacking the SOCS-6 gene exhibit mild growth retardation Krebs, DL; Uren, RT; Metcalf, D; Rakar, S; Zhang, JG; Starr, R; De Souza, DP; Hanzinikolas, K; Eyles, J; Connolly, LM; Simpson, RJ; Nicola, NA; Nicholson, SE; Baca, M; Hilton, DJ; Alexander, WS 分享 收藏
SOCS5 is expressed in primary B and T lymphoid cells but is dispensable for lymphocyte production and function Brender, C; Columbus, R; Metcalf, D; Handman, E; Starr, R; Huntington, N; Tarlinton, D; Odum, N; Nicholson, SE; Nicola, NA; Hilton, DJ; Alexander, WS 分享 收藏
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Overexpression of Lmo2 initiates T-lymphoblastic leukemia via impaired thymocyte competition Abdulla, Hesham D. D.; Alserihi, Raed; Flensburg, Christoffer; Abeysekera, Waruni; Luo, Meng-Xiao; Gray, Daniel H. D.; Liu, Xiaodong; Smyth, Gordon K. K.; Alexander, Warren S. S.; Majewski, Ian J. J.; McCormack, Matthew P. P. 分享 收藏
Generation of a CRISPR activationmouse that enables modelling of aggressive lymphoma and interrogation of venetoclax resistance (vol 13, 4739, 2022) Deng, Yexuan; Diepstraten, Sarah T.; Potts, Margaret A.; Giner, Goknur; Trezise, Stephanie; Ng, Ashley P.; Healey, Gerry; Kane, Serena R.; Cooray, Amali; Behrens, Kira; Heidersbach, Amy; Kueh, Andrew J.; Pal, Martin; Wilcox, Stephen; Tai, Lin; Alexander, Warren S.; Visvader, Jane E.; Nutt, Stephen L.; Strasser, Andreas; Haley, Benjamin; Zhao, Quan; Kelly, Gemma L.; Herold, Marco J. 分享 收藏
Generation of a CRISPR activation mouse that enables modelling of aggressive lymphoma and interrogation of venetoclax resistance Deng, Yexuan; Diepstraten, Sarah T.; Potts, Margaret A.; Giner, Goeknur; Trezise, Stephanie; Ng, Ashley P.; Healey, Gerry; Kane, Serena R.; Cooray, Amali; Behrens, Kira; Heidersbach, Amy; Kueh, Andrew J.; Pal, Martin; Wilcox, Stephen; Tai, Lin; Alexander, Warren S.; Visvader, Jane E.; Nutt, Stephen L.; Strasser, Andreas; Haley, Benjamin; Zhao, Quan; Kelly, Gemma L.; Herold, Marco J. 分享 收藏
Differential requirement for the Polycomb repressor complex 2 in dendritic cell and tissue-resident myeloid cell homeostasis Zhan, Yifan; Zhang, Yuxia; Zhang, Shengbo; Coughlan, Hannah; Baldoni, Pedro L.; Jacquelot, Nicolas; Cao, Wang H. J.; Preston, Simon; Louis, Cynthia; Rautela, Jai; Pellegrini, Marc; Wicks, Ian P.; Alexander, Warren S.; Harrison, Leonard C.; Lew, Andrew M.; Smyth, Gordon K.; Nutt, Stephen L.; Chopin, Michael 分享 收藏
Proteomic analyses reveal that immune integrins are major targets for regulation by Membrane-Associated Ring-CH (MARCH) proteins MARCH2, 3, 4 and 9 Sandow, Jarrod J.; Webb, Andrew I.; Stockwell, Dina; Kershaw, Nadia J.; Tan, Cyrus; Ishido, Satoshi; Alexander, Warren S.; Hilton, Douglas J.; Babon, Jeffrey J.; Nicola, Nicos A. 分享 收藏
The necroptotic cell death pathway operates in megakaryocytes, but not in platelet synthesis Moujalled, Diane; Gangatirkar, Pradnya; Kauppi, Maria; Corbin, Jason; Lebois, Marion; Murphy, James M.; Lalaoui, Najoua; Hildebrand, Joanne M.; Silke, John; Alexander, Warren S.; Josefsson, Emma C. 分享 收藏
T-ALL can evolve to oncogene independence Abdulla, Hesham; Vo, Anh; Shields, Benjamin J.; Davies, Tenae J.; Jackson, Jacob T.; Alserihi, Raed; Viney, Elizabeth M.; Wong, Tin; Yan, Feng; Wong, Nicholas C.; Demoen, Lisa; Curtis, David J.; Alexander, Warren S.; Van Vlierberghe, Pieter; Dickins, Ross A.; McCormack, Matthew P. 分享 收藏