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Phase Ia/b Multicenter Study of BPM31510IV Targeting Mitochondrial Metabolism/Warburg Effect as Monotherapy and Combination Chemotherapy in Solid Tumor Patients Ia/b期多中心研究：BPM31510IV单药治疗和联合化疗在实体瘤患者中靶向线粒体代谢/瓦伯格效应的应用 Subbiah, Vivek; Yu, Peter P.; Sarangarajan, Rangaprasad; Kiebish, Michael A.; Rodrigues, Leonardo O.; Miller, Gregory M.; Akmaev, Viatcheslav R.; Luan, Shen; McCook, John P.; Tanna, Nikunj; Reilly, Tracey; Chen, Emily; Bussberg, Valerie; Ravipaty, Shobha; Vishnudas, Vivek K.; Gesta, Stephane; Lucius, David; Bruce, Can; Hazarika, Suwagmani; Lyng, Arianne; Klotz, Allison; Tolstikov, Vladimir; Stevens, Janice; Chua, Victoria S.; Granger, Elder; Tekumalla, Poornima K.; Benaim, Ely; Modur, Vijay; Rudoltz, Marc S.; Song, Paul Y.; Tagawa, Scott T.; Hendifer, Andrew; Chawla, Sant P.; Shah, Manish A.; Hong, David S.; Zinner, Ralph; Narain, Niven R.; Kundranda, Madappa N. 分享 收藏
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SaLudo: a randomized phase IIb/III study of lurbinectedin plus doxorubicin as first-line treatment in leiomyosarcoma SaLudo: lurbinectedin加阿霉素作为平滑肌肉瘤一线治疗的随机IIb/III期研究 Cote, Gregory M.; Chawla, Sant P.; Demetri, George; Kasper, Bernd; Jones, Robin L.; Broto, Javier Martin; Wooley, Joseph; Weiss, Mia C.; Tafuto, Salvatore; Badalamenti, Giuseppe; Carrasco, Irene; Peinado, Paloma; Blay, Jean-Yves; Boggio, Gaston; Fernandez, Cristian; Nieto, Antonio; Kahatt, Carmen; Alfaro, Vicente; Le Cesne, Axel 分享 收藏
Update on SAINT: A phase II study using trabectedin (T) in combination with ipilimumab (I) and nivolumab (N) in previously treated soft tissue sarcoma SAINT研究进展：一项关于在既往治疗过的软组织肉瘤中使用曲贝替定（T）联合伊匹木单抗（I）和纳武利尤单抗（N）的II期研究 Agarwal, A. D.; Jeffrey, S.; Cechini, R.; Kumar, V.; Omelchenko, N.; Ballon, J.; Moradkhani, A.; Alcala, V. S. Chua; Chawla, N. S.; Mahesh, S.; Chawla, S. P.; Gordon, E. M. 分享 收藏
Results of TNT: A phase II study using talimogene laherparepvec, nivolumab and trabectedin for advanced leiomyosarcoma and liposarcoma [NCT# 03886311] TNT研究的结果：一项使用talimogene laherparepvec、nivolumab和trabectedin治疗晚期平滑肌肉瘤和脂肪肉瘤的II期研究[NCT# 03886311] Chawla, S. P.; Kumar, V.; Omelchenko, N.; Jeffrey, S.; Agarwal, A. D.; Cechini, R.; Alcala, V. S. Chua; Quon, D.; Wong, S.; Gordon, E. M. 分享 收藏
Proceedings of the think tank for osteosarcoma medical advisory board meeting 骨肉瘤医疗顾问委员会智库会议纪要 Chawla, S. P.; Van Tine, B. A.; Federman, N.; Schwab, J.; Jones, R. L.; Subbiah, V.; Swaney, W.; Chawla, N. S.; Spencer, T.; Afshar, N.; Hoos, W.; Feldman, N.; Gordon, E. M. 分享 收藏
LINNOVATE: A Phase 1/2 study of safety/efficacy using lurbinectedin, combined with ipilimumab, and nivolumab for advanced soft tissue sarcomas (NCT05876715) Gordon, Erlinda M.; Omelchenko, Nadezhda; Jeffrey, Samantha; Kumar, Vaishali; Chawla, Neal S.; Seetharam, Mahesh; Chua, Victoria; Moradkhani, Ania; Quon, Doris; Wong, Steven; Chawla, Sant 分享 收藏
Phase 1b trial Mipasetamab Uzoptirine (ADCT-601-102) dose escalation in patients with advanced bone and soft tissue sarcomas Van Tine, Brian Andrew; Chen, Christopher T.; Moreno, Victor; Davis, Elizabeth J.; de Miguel, Maria J.; Italiano, Antoine; Saada-Bouzid, Esma; Milhem, Mohammed; Valverde, Claudia; Chawla, Sant P.; Naqash, Abdul Rafeh; Carter, Louise; Jones, Robin; Conti, Ilaria; Boni, Joe; Havenith, Karin; LeBruchec, Yvan; Pantano, Serafino; Blay, Jean-Yves 分享 收藏
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A phase I trial of SON-1010, a tumor-targeted, interleukin-12-linked, albumin-binding cytokine, shows favorable pharmacokinetics, pharmacodynamics, and safety in healthy volunteers Kenney, Richard T.; Cini, John K.; Dexter, Susan; DaFonseca, Manuel; Bingham, Justus; Kuan, Isabelle; Chawla, Sant P.; Polasek, Thomas M.; Lickliter, Jason; Ryan, Philip J. 分享 收藏
Results of SOC-2082 phase II study using metronomic gemcitabine, doxorubicin, and docetaxel plus nivolumab as second/third-line therapy for advanced leiomyosarcoma Chawla, N. S.; Omelchenko, N.; Makrievski, S.; De Melo, G. Leao; Brigham, D.; Ahari, A.; Alcala, V. S. Chua; Moradhkani, A.; Quon, D.; Wong, S.; Chawla, S. P.; Gordon, E. M. 分享 收藏
Artificial intelligence analysis shows enhanced CCNG1 expression in sarcoma tumors, a novel biomarker for DeltaRex-G tumor targeted retrovector encoding a CCNG1 inhibitor gene 人工智能分析显示肉瘤肿瘤中CCNG1表达增强，这是deltarex-g肿瘤靶向逆转录载体编码CCNG1抑制剂基因的新型生物标志物 Chawla, S. P.; Omelchenko, N.; Eid, C.; Jeffrey, S.; Shekhovtsova, Z.; Suryamohan, K.; Younesi, E.; Omelchenko, A.; Ahari, A.; Valencia, C.; Chawla, N. S.; Brigham, D.; Gordon, E. M. 分享 收藏
phase I clinical results of SQ3370, a doxorubicin-based click chemistry therapeutic in advanced solid tumor patients Chawla, S. P.; Kwatra, V.; Subbiah, V.; Bui, N.; Bhadri, V. A.; Weiss, M. C.; Agulnik, M.; Ryan, C. W.; Aleckovic, M.; Srinivasan, S.; Zakharian, M.; Nguyen, T-H.; Oneto, J. Mejia; Abella, S.; Guminski, A. D. 分享 收藏
Activity of TNT: a phase 2 study using talimogene laherparepvec, nivolumab and trabectedin for previously treated patients with advanced sarcomas (NCT# 03886311) Chawla, Sant P. P.; Tellez, Walter Andree; Chomoyan, Hripsime; Valencia, Chrysler; Ahari, Amir; Omelchenko, Nadezhda; Makrievski, Stefan; Brigham, Don A. A.; Chua-Alcala, Victoria; Quon, Doris; Moradkhani, Ania; Gordon, Erlinda M. M. 分享 收藏
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The Midwest Sarcoma Trials Partnership: Bridging Academic and Community Networks in a Collaborative Approach to Sarcoma Heater, Natalie K.; Okuno, Scott; Robinson, Steven; Attia, Steven; Seetharam, Mahesh; Siontis, Brittany L.; Yoon, Janet; Chawla, Sant; Milhem, Mohammed M.; Monga, Varun; Skubitz, Keith; Charlson, John; Hirbe, Angela C.; Weiss, Mia C.; Van Tine, Brian; Agulnik, Mark 分享 收藏
Nirogacestat, a γ-Secretase Inhibitor for Desmoid Tumors Gounder, Mrinal; Ratan, Ravin; Alcindor, Thierry; Schoeffski, Patrick; van der Graaf, Winette T.; Wilky, Breelyn A.; Riedel, Richard F.; Lim, Allison; Smith, L. Mary; Moody, Stephanie; Attia, Steven; Chawla, Sant; D'Amato, Gina; Federman, Noah; Merriam, Priscilla; Van Tine, Brian A.; Vincenzi, Bruno; Benson, Charlotte; Bui, Nam Quoc; Chugh, Rashmi; Tinoco, Gabriel; Charlson, John; Dileo, Palma; Hartner, Lee; Lapeire, Lore; Mazzeo, Filomena; Palmerini, Emanuela; Reichardt, Peter; Stacchiotti, Silvia; Bailey, Howard H.; Burgess, Melissa A.; Cote, Gregory M.; Davis, Lara E.; Deshpande, Hari; Gelderblom, Hans; Grignani, Giovanni; Loggers, Elizabeth; Philip, Tony; Pressey, Joseph G.; Kummar, Shivaani; Kasper, Bernd 分享 收藏
Lurbinectedin in patients with pretreated neuroendocrine tumours: Results from a phase II basket study Longo-Munoz, Federico; Castellano, Daniel; Alexandre, Jerome; Chawla, Sant P.; Fernandez, Cristian; Kahatt, Carmen; Alfaro, Vicente; Siguero, Mariano; Zeaiter, Ali; Moreno, Victor; Sanz-Garcia, Enrique; Awada, Ahmad; Santaballa, Ana; Subbiah, Vivek 分享 收藏
A phase II study of TAS-117 in patients with advanced solid tumors harboring germline PTEN-inactivating mutations Rodon, Jordi; Funchain, Pauline; Laetsch, Theodore W.; Arkenau, Hendrik-Tobias; Hervieu, Alice; Singer, Christian F.; Murciano-Goroff, Yonina R.; Chawla, Sant P.; Anthony, Kristin; Yamamiya, Ikuo; Liu, Mei; Halim, Abdel-Baset; Benhadji, Karim A.; Takahashi, Osamu; Delaloge, Suzette 分享 收藏
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