Wayne A. Phillips - Publications, H-index & Citations

Wayne A. Phillips

peter maccallum cancer center

54H指数

372论文数

1.1W被引数

收录论文 104

发表时间

Ubiquitous expression of an activating mutation in the Pik3ca gene reprograms glucose and lipid metabolism in mice Pik3ca基因中激活性突变的泛表达重塑了小鼠的葡萄糖和脂质代谢

PLOS ONE

IF2.6

2025-05-12

OAAI

Caiazzo, Sabrina; Watt, Matthew J.; Dodd, Garron T.; Bayliss, Jacqueline; Thomas, Helen; Smith, Lorey K.; Mitchell, Camilla B.; Phillips, Wayne A.

Targeting a STING agonist to perivascular macrophages in prostate tumors delays resistance to androgen deprivation therapy 将STING激动剂靶向前列腺肿瘤的血管周围巨噬细胞可延迟对雄激素剥夺疗法的抵抗力

JOURNAL FOR IMMUNOTHERAPY OF CANCER

IF10.6

2024-07-25

OAAI

Al-janabi, Haider; Moyes, Katy; Allen, Richard; Fisher, Matthew; Crespo, Mateus; Gurel, Bora; Rescigno, Pasquale; de Bono, Johann; Nunns, Harry; Bailey, Christopher; Junker-Jensen, Anna; Muthana, Munitta; Phillips, Wayne A.; Pearson, Helen B.; Taplin, Mary-Ellen; Brown, Janet E.; Lewis, Claire E.

Direct activation of PI3K in osteoblasts and osteocytes strengthens murine bone through sex-specific actions on cortical surfaces

JOURNAL OF BONE AND MINERAL RESEARCH

IF5.9

2024-07-03

PREAI

Wee, Natalie K. Y.; McGregor, Narelle E.; Walker, Emma C.; Poulton, Ingrid J.; Dang, Michelle Kieu Mi; Gooi, Jonathan H.; Phillips, Wayne A.; Sims, Natalie A.

Delineating functional drivers of esophageal adenocarcinoma to identify synthetic lethal interactions

MOLECULAR CANCER THERAPEUTICS

IF5.5

2024-06-10

PREAI

Milne, Julia V.; Mustafa, Ebtihal; Fujihara, Kenji; Kusnadi, Eric; Trigos, Anna; Thio, Niko; Pechlivanis, Maree; Cabalag, Carlos; Gulati, Twishi; Simpson, Kaylene; Duong, Cuong; Furic, Luc; Phillips, Wayne; Clemons, Nicholas

Delineating functional drivers of esophageal adenocarcinoma to identify synthetic lethal interactions

MOLECULAR CANCER THERAPEUTICS

IF5.5

2024-06-10

PREAI

Multi-omics approach reveals a SMAD4-deficiency signature, translational reprogramming and synthetic lethality in esophageal adenocarcinom

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Milne, Julia V.; Fujihara, Kenji; Kusnadi, Eric; Pechlivanis, Maree; Thio, Niko; Cabalag, Carlos; Gulati, Twishi; Gotovac, Jovana; Simpson, Kaylene; Duong, Cuong; Furic, Luc; Phillips, Wayne; Clemons, Nicholas

Caspase-2 protects against ferroptotic cell death Caspase-2可防止铁性细胞死亡

CELL DEATH & DISEASE

IF9.6

2024-03-01

OAAI

Dawar, Swati; Benitez, Mariana C.; Lim, Yoon; Dite, Toby A.; Yousef, Jumana M.; Thio, Niko; Garciaz, Sylvain; Jackson, Thomas D.; Milne, Julia V.; Dagley, Laura F.; Phillips, Wayne A.; Kumar, Sharad; Clemons, Nicholas J.

Loss of SMAD4 unleashes mTOR and increases dependency on cap-dependent translation in esophageal tumorigenesis

MOLECULAR CANCER THERAPEUTICS

IF5.5

2023-12-01

PREAI

Milne, Julia V.; Mustafa, Ebtihal; Fujihara, Kenji; Kusnadi, Eric; Thio, Niko; Pechlivanis, Maree; Cabalag, Carlos; Gulati, Twishi; Simpson, Kaylene; Duong, Cuong; Furic, Luc; Phillips, Wayne; Clemons, Nicholas J.

PLEKHS1 drives PI3Ks and remodels pathway homeostasis in PTEN-null prostate PLEKHS1在PTEN无效的前列腺中驱动PI3Ks并重塑通路稳态

MOLECULAR CELL

IF16.6

2023-08-01

OAAI

Chessa, Tamara A. M.; Jung, Piotr; Anwar, Arqum; Suire, Sabine; Anderson, Karen E.; Barneda, David; Kielkowska, Anna; Sadiq, Barzan A.; Lai, Ieng Wai; Felisbino, Sergio; Turnham, Daniel J.; Pearson, Helen B.; Phillips, Wayne A.; Sasaki, Junko; Sasaki, Takehiko; Oxley, David; Spensberger, Dominik; Segonds-Pichon, Anne; Wilson, Michael; Walker, Simon; Okkenhaug, Hanneke; Cosulich, Sabina; Hawkins, Phillip T.; Stephens, Len R.

Regulation of phosphoinositide 3-kinase by its intrinsic serine kinase activity in vivo

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

OAAI

Foukas, LC; Beeton, CA; Jensen, J; Phillips, WA; Shepherd, PR

YBX1 integration of oncogenic PI3K/mTOR signalling regulates the fitness of malignant epithelial cells 致癌PI3K/mTOR信号的YBX1整合调节恶性上皮细胞的适应性

NATURE COMMUNICATIONS

IF15.7

2023-03-22

OAAI

Bai, Yuchen; Gotz, Carolin; Chincarini, Ginevra; Zhao, Zixuan; Slaney, Clare; Boath, Jarryd; Furic, Luc; Angel, Christopher; Jane, Stephen M.; Phillips, Wayne A.; Stacker, Steven A.; Farah, Camile S.; Darido, Charbel

Inhibition of BMP2 and BMP4 Represses Barrett's Esophagus While Enhancing the Regeneration of Squamous Epithelium in Preclinical Models

CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY

IF7.4

2023-01-01

OAAI

Correia, Ana C. P.; Straub, Danielle; Read, Matthew; Hoefnagel, Sanne J. M.; Romero-Pinedo, Salvador; Abadia-Molina, Ana C.; Clemons, Nicholas J.; Wang, Kenneth; Calpe, Silvia; Phillips, Wayne; Krishnadath, Kausilia K.

ASO Visual Abstract: Tumor-Infiltrating Neutrophils after Neoadjuvant Therapy are Associated with Poor Prognosis in Esophageal Cancer

ANNALS OF SURGICAL ONCOLOGY

IF3.5

2022-10-11

PREAI

Cabalag, Carlos S.; Prall, Owen W. J.; Ciciulla, John; Galea, Laurence A.; Thio, Niko; Jayawardana, Madawa; Leong, Trishe Y. M.; Milne, Julia V.; Fujihara, Kenji M.; Chong, Lynn; Hii, Michael W.; Arnau, Gisela Mir; Neeson, Paul J.; Phillips, Wayne A.; Duong, Cuong P.; Clemons, Nicholas J.

Tumor-Infiltrating Neutrophils after Neoadjuvant Therapy are Associated with Poor Prognosis in Esophageal Cancer

ANNALS OF SURGICAL ONCOLOGY

IF3.5

2022-10-02

OAAI

ASO Author Reflections: Are Tumor-Infiltrating Neutrophils Drivers of Metastatic Disease in Esophageal Cancer Patients Treated with Neoadjuvant Therapy?

ANNALS OF SURGICAL ONCOLOGY

IF3.5

2022-09-29

OAAI

Cabalag, Carlos S.; Phillips, Wayne A.; Duong, Cuong P.; Clemons, Nicholas J.

Eprenetapopt triggers ferroptosis, inhibits NFS1 cysteine desulfurase, and synergizes with serine and glycine dietary restriction

SCIENCE ADVANCES

IF12.5

2022-09-16

OAAI

Fujihara, Kenji M.; Zhang, Bonnie Z.; Jackson, Thomas D.; Ogunkola, Moses O.; Nijagal, Brunda; Milne, Julia, V; Sallman, David A.; Ang, Ching-Seng; Nikolic, Iva; Kearney, Conor J.; Hogg, Simon J.; Cabalag, Carlos S.; Sutton, Vivien R.; Watt, Sally; Fujihara, Asuka T.; Trapani, Joseph A.; Simpson, Kaylene J.; Stojanovski, Diana; Leimkuhler, Silke; Haupt, Sue; Phillips, Wayne A.; Clemons, Nicholas J.

Selective targeting BMP2 and 4 in SMAD4 negative esophageal adenocarcinoma inhibits tumor growth and aggressiveness in preclinical models

CELLULAR ONCOLOGY

IF4.8

2022-07-28

OAAI

Li, Shulin; Hoefnagel, Sanne J. M.; Read, Matthew; Meijer, Sybren; Henegouwen, Mark I. van Berge; Gisbertz, Suzanne S.; Bonora, Elena; Liu, David S. H.; Phillips, Wayne A.; Calpe, Silvia; Correia, Ana C. P.; Sancho-Serra, Maria D. C.; Mattioli, Sandro; Krishnadath, Kausilia K.

Epithelial de-differentiation triggered by co-ordinate epigenetic inactivation of the EHF and CDX1 transcription factors drives colorectal cancer progression EHF和CDX1转录因子的协同表观失活引发的上皮去分化驱动结直肠癌进展

CELL DEATH AND DIFFERENTIATION

IF15.4

2022-05-23

OAAI

Luk, Ian Y.; Jenkins, Laura J.; Schoffer, Kael L.; Ng, Irvin; Tse, Janson W. T.; Mouradov, Dmitri; Kaczmarczyk, Stanislaw; Nightingale, Rebecca; Burrows, Allan D.; Anderson, Robin L.; Arango, Diego; Dopeso, Higinio; Croft, Larry; Richardson, Mark F.; Sieber, Oliver M.; Liao, Yang; Mooi, Jennifer K.; Vukelic, Natalia; Reehorst, Camilla M.; Afshar-Sterle, Shoukat; Whitehall, Vicki L. J.; Fennell, Lochlan; Abud, Helen E.; Tebbutt, Niall C.; Phillips, Wayne A.; Williams, David S.; Shi, Wei; Mielke, Lisa A.; Ernst, Matthias; Dhillon, Amardeep S.; Clemons, Nicholas J.; Mariadason, John M.

Elevation of fatty acid desaturase 2 in esophageal adenocarcinoma increases polyunsaturated lipids and may exacerbate bile acid-induced DNA damage 食管腺癌中脂肪酸去饱和酶2的升高会增加多不饱和脂质，并可能加剧胆汁酸诱导的DNA损伤

CLINICAL AND TRANSLATIONAL MEDICINE

IF6.8

2022-05-12

OAAI

Molendijk, Jeffrey; Kolka, Cathryn M.; Cairns, Henry; Brosda, Sandra; Mohamed, Ahmed; Shah, Alok K.; Brown, Ian; Hodson, Mark P.; Hennessy, Thomas; Liu, Guanghao; Stoll, Thomas; Richards, Renee S.; Gartside, Michael; Patel, Kalpana; Clemons, Nicholas J.; Phillips, Wayne A.; Barbour, Andrew; Westerhuis, Johan A.; Hill, Michelle M.

Physiological expression of PI3K H1047R mutation reveals its anti-metastatic potential in ErbB2-driven breast cancer

ONCOGENE

IF7.3

2022-05-10

PREAI

Simond, Alexandra M.; Bui, Tung; Zuo, Dongmei; Sanguin-Gendreau, Virginie; Rao, Trisha; Phillips, Wayne A.; Cardiff, Robert D.; Muller, William J.

研究方向