未登录 Brain-specific deletion of GIT1 impairs cognition and alters phosphorylation of synaptic protein networks implicated in schizophrenia susceptibility Fass, Daniel M.; Lewis, Michael C.; Ahmad, Rushdy; Szucs, Matthew J.; Zhang, Qiangge; Fleishman, Morgan; Wang, Dongqing; Kim, Myung Jong; Biag, Jonathan; Carr, Steven A.; Scolnick, Edward M.; Premont, Richard T.; Haggarty, Stephen J. 分享 收藏
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The schizophrenia-associated variant in SLC39A8 alters protein glycosylation in the mouse brain Mealer, Robert G.; Williams, Sarah E.; Noel, Maxence; Yang, Bo; D'Souza, Alexandria K.; Nakata, Toru; Graham, Daniel B.; Creasey, Elizabeth A.; Cetinbas, Murat; Sadreyev, Ruslan I.; Scolnick, Edward M.; Woo, Christina M.; Smoller, Jordan W.; Xavier, Ramnik J.; Cummings, Richard D. 分享 收藏
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Mammalian brain glycoproteins exhibit diminished glycan complexity compared to other tissues 与其他组织相比，哺乳动物脑糖蛋白表现出降低的聚糖复杂性 Williams, Sarah E.; Noel, Maxence; Lehoux, Sylvain; Cetinbas, Murat; Xavier, Ramnik J.; Sadreyev, Ruslan, I; Scolnick, Edward M.; Smoller, Jordan W.; Cummings, Richard D.; Mealer, Robert G. 分享 收藏
The schizophrenia risk locus in SLC39A8 alters brain metal transport and plasma glycosylation Mealer, Robert G.; Jenkins, Bruce G.; Chen, Chia-Yen; Daly, Mark J.; Ge, Tian; Lehoux, Sylvain; Marquardt, Thorsten; Palmer, Christopher D.; Park, Julien H.; Parsons, Patrick J.; Sackstein, Robert; Williams, Sarah E.; Cummings, Richard D.; Scolnick, Edward M.; Smoller, Jordan W. 分享 收藏
Selective inhibition of glycogen synthase kinase 3α corrects pathophysiology in a mouse model of fragile X syndrome McCamphill, Patrick K.; Stoppel, Laura J.; Senter, Rebecca K.; Lewis, Michael C.; Heynen, Arnold J.; Stoppel, David C.; Sridhar, Vinay; Collins, Katie A.; Shi, Xi; Pan, Jen Q.; Madison, Jon; Cottrell, Jeffrey R.; Huber, Kimberly M.; Scolnick, Edward M.; Holson, Edward B.; Wagner, Florence F.; Bear, Mark F. 分享 收藏
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Contributions of common genetic variants to risk of schizophrenia among individuals of African and Latino ancestry Bigdeli, Tim B.; Genovese, Giulio; Georgakopoulos, Penelope; Meyers, Jacquelyn L.; Peterson, Roseann E.; Iyegbe, Conrad O.; Medeiros, Helena; Valderrama, Jorge; Achtyes, Eric D.; Kotov, Roman; Stahl, Eli A.; Abbott, Colony; Azevedo, Maria Helena; Belliveau, Richard A.; Bevilacqua, Elizabeth; Bromet, Evelyn J.; Byerley, William; Carvalho, Celia Barreto; Chapman, Sinead B.; DeLisi, Lynn E.; Dumont, Ashley L.; O'Dushlaine, Colm; Evgrafov, Oleg V.; Fochtmann, Laura J.; Gage, Diane; Kennedy, James L.; Kinkead, Becky; Macedo, Antonio; Moran, Jennifer L.; Morley, Christopher P.; Dewan, Mantosh J.; Nemesh, James; Perkins, Diana O.; Purcell, Shaun M.; Rakofsky, Jeffrey J.; Scolnick, Edward M.; Sklar, Brooke M.; Sklar, Pamela; Smoller, Jordan W.; Sullivan, Patrick F.; Macciardi, Fabio; Marder, Stephen R.; Gur, Ruben C.; Gur, Raquel E.; Braff, David L.; Calkins, Monica E.; Freedman, Robert R.; Green, Michael F.; Greenwood, Tiffany A.; Lazzeroni, Laura C.; Light, Gregory A.; Nuechterlein, Keith H.; Radant, Allen D.; Seidman, Larry J.; Siever, Larry J.; Silverman, Jeremy M.; Stone, William S.; Sugar, Catherine A.; Swerdlow, Neal R.; Tsuang, Debby W.; Tsuang, Ming T.; Turetsky, Bruce I.; Nicolini, Humberto; Escamilla, Michael A.; Vawter, Marquis P.; Sobell, Janet L.; Malaspina, Dolores; Lehrer, Douglas S.; Buckley, Peter F.; Rapaport, Mark H.; Knowles, James A.; Fanous, Ayman H.; Pato, Michele T.; McCarroll, Steven A.; Pato, Carlos N. 分享 收藏
Exploiting an Asp-Glu switch in glycogen synthase kinase 3 to design paralog-selective inhibitors for use in acute myeloid leukemia 利用糖原合酶激酶3中的asp-glu开关设计用于急性髓细胞性白血病的旁系同源物选择性抑制剂 Wagner, Florence F.; Benajiba, Lina; Campbell, Arthur J.; Weiwer, Michel; Sacher, Joshua R.; Gale, Jennifer P.; Ross, Linda; Puissant, Alexandre; Alexe, Gabriela; Conway, Amy; Back, Morgan; Pikman, Yana; Galinsky, Ilene; DeAngelo, Daniel J.; Stone, Richard M.; Kaya, Taner; Shi, Xi; Robers, Matthew B.; Machleidt, Thomas; Wilkinson, Jennifer; Hermine, Olivier; Kung, Andrew; Stein, Adam J.; Lakshminarasimhan, Damodharan; Hemann, Michael T.; Scolnick, Edward; Zhang, Yan-Ling; Pan, Jen Q.; Stegmaier, Kimberly; Holson, Edward B. 分享 收藏
Functionally Biased D2R Antagonists: Targeting the β-Arrestin Pathway to Improve Antipsychotic Treatment Weiwer, Michel; Xu, Qihong; Gale, Jennifer P.; Lewis, Michael; Campbell, Arthur J.; Schroeder, Frederick A.; van de Bittner, Genevieve C.; Walk, Michelle; Amaya, Aldo; Su, Ping; Dordevic, Luka; Sacher, Joshua R.; Skepner, Adam; Fei, David; Dennehy, Kelly; Nguyen, Shannon; Faloon, Patrick W.; Perez, Jose; Cottrell, Jeffrey R.; Liu, Fang; Palmer, Michelle; Pan, Jen Q.; Hooker, Jacob M.; Zhang, Yan-Ling; Scolnick, Edward; Wagner, Florence F.; Holson, Edward B. 分享 收藏
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Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects 来自41,321受试者的全基因组研究的拷贝数变异对精神分裂症的贡献 Marshall, Christian R.; Howrigan, Daniel P.; Merico, Daniele; Thiruvahindrapuram, Bhooma; Wu, Wenting; Greer, Douglas S.; Antaki, Danny; Shetty, Aniket; Holmans, Peter A.; Pinto, Dalila; Gujral, Madhusudan; Brandler, William M.; Malhotra, Dheeraj; Wang, Zhouzhi; Fajarado, Karin V. Fuentes; Maile, Michelle S.; Ripke, Stephan; Agartz, Ingrid; Albus, Margot; Alexander, Madeline; Amin, Farooq; Atkins, Joshua; Bacanu, Silviu A.; Belliveau, Richard A., Jr.; Bergen, Sarah E.; Ertalan, Marcelo; Bevilacqua, Elizabeth; Bigdeli, Tim B.; Black, Donald W.; Bruggeman, Richard; Buccola, Nancy G.; Buckner, Randy L.; Bulik-Sullivan, Brendan; Byerley, William; Cahn, Wiepke; Cai, Guiqing; Cairns, Murray J.; Campion, Dominique; Cantor, Rita M.; Carr, Vaughan J.; Carrera, Noa; Catts, Stanley V.; Chambert, Kimberley D.; Cheng, Wei; Cloninger, C. Robert; Cohen, David; Cormican, Paul; Craddock, Nick; Crespo-Facorro, Benedicto; Crowley, James J.; Curtis, David; Davidson, Michael; Davis, Kenneth L.; Degenhardt, Franziska; Del Favero, Jurgen; DeLisi, Lynn E.; Dikeos, Dimitris; Dinan, Timothy; Djurovic, Srdjan; Donohoe, Gary; Drapeau, Elodie; Duan, Jubao; Dudbridge, Frank; Eichhammer, Peter; Eriksson, Johan; Escott-Price, Valentina; Essioux, Laurent; Fanous, Ayman H.; Farh, Kai-How; Farrell, Martilias S.; Frank, Josef; Franke, Lude; Freedman, Robert; Freimer, Nelson B.; Friedman, Joseph I.; Forstner, Andreas J.; Fromer, Menachem; Genovese, Giulio; Georgieva, Lyudmila; Gershon, Elliot S.; Giegling, Ina; Giusti-Rodriguez, Paola; Godard, Stephanie; Goldstein, Jacqueline I.; Gratten, Jacob; de Haan, Lieuwe; Hamshere, Marian L.; Hansen, Mark; Hansen, Thomas; Haroutunian, Vahram; Hartmann, Annette M.; Henskens, Frans A.; Herms, Stefan; Hirschhorn, Joel N.; Hoffinann, Per; Hofman, Andrea; Huang, Hailiang; Ikeda, Masashi; Joa, Inge; Kahler, Anna K.; Kahn, Rene S.; Kalaydjieva, Luba; Karjalainen, Juha; Kavanagh, David; Keller, Matthew C.; Kelly, Brian J.; Kennedy, James L.; Kim, Yunjung; Knowles, James A.; Konte, Bettina; Laurent, Claudine; Lee, Phil; Lee, S. Hong; Legge, Sophie E.; Lerer, Bernard; Levy, Deborah L.; Liang, Kung-Yee; Lieberman, Jeffrey; Lonnqvist, Jouko; Loughland, Carmel M.; Magnusson, Patrik K. E.; Maher, Brion S.; Maier, Wolfgang; Mallet, Jacques; Mattheisen, Manuel; Mattingsdal, Morten; McCarley, Robert W.; McDonald, Colm; McIntosh, Andrew M.; Meier, Sandra; Meijer, Carin J.; Melle, Ingrid; Mesholam-Gately, Raquelle I.; Metspalu, Andres; Michie, Patricia T.; Milani, Lili; Milanova, Vihra; Mokrab, Younes; Morris, Derek W.; Muller-Myhsok, Bertram; Murphy, Kieran C.; Murray, Robin M.; Myin-Germeys, Inez; Nenadic, Igor; Nertney, Deborah A.; Nestadt, Gerald; Nicodemus, Kristin K.; Nisenbaum, Laura; Nordin, Annelie; O'Callaghan, Eadbhard; O'Dushlaine, Colm; Oh, Sang-Yun; Olincy, Ann; Olsen, Line; O'Neill, F. Anthony; Van Os, Jim; Pantelis, Christos; Papadimitriou, George N.; Parkhomenko, Elena; Pato, Michele T.; Paunio, Tiina; Perkins, Diana O.; Pers, Tune H.; Pietilainen, Olli; Pimm, Jonathan; Pocklington, Andrew J.; Powell, John; Price, Alkes; Pulver, Ann E.; Purcell, Shaun M.; Quested, Digby; Rasmussen, Henrik B.; Reichenberg, Abraham; Reimers, Mark A.; Richards, Alexander L.; Roffman, Joshua L.; Roussos, Panos; Ruderfer, Douglas M.; Salomaa, Veikko; Sanders, Alan R.; Savitz, Adam; Schall, Ulrich; Schulze, Thomas G.; Schwab, Sibylle G.; Scolnick, Edward M.; Scott, Rodney J.; Seidman, Larry J.; Shi, Jianxin; Silverman, Jeremy M.; Smoller, Jordan W.; Soderman, Erik; Spencer, Chris C. A.; Stahl, Eli A.; Strengman, Eric; Strohmaier, Jana; Stroup, T. Scott; Suvisaari, Jaana; Svrakic, Dragan M.; Szatkiewicz, Jin P.; Thirumalai, Srinivas; Tooney, Paul A.; Veijola, Juha; Visscher, Peter M.; Waddington, John; Walsh, Dermot; Webb, Bradley T.; Weiser, Mark; Wildenauer, Dieter B.; Williams, Nigel M.; Williams, Stephanie; Witt, Stephanie H.; Wolen, Aaron R.; Wormley, Brandon K.; Wray, Naomi R.; Wu, Jing Qin; Zai, Clement C.; Adolfsson, Rolf; Andreassen, Ole A.; Blackwood, Douglas H. R.; Bramon, Elvira; Buxbaum, Joseph D.; Cichon, Sven; Collier, David A.; Corvin, Aiden; Daly, Mark J.; Darvasi, Ariel; Domenici, Enrico; Esko, Tonu; Gejman, Pablo V.; Gill, Michael; Gurling, Hugh; Hultman, Christina M.; Iwata, Nakao; Jablensky, Assen V.; Jonsson, Erik G.; Kendler, Kenneth S.; Kirov, George; Knight, Jo; Levinson, Douglas F.; Li, Qingqin S.; McCarroll, Steven A.; McQuillin, Andrew; Moran, Jennifer L.; Mowry, Bryan J.; Nothen, Markus M.; Ophoff, Roel A.; Owen, Michael J.; Palotie, Aarno; Pato, Carlos N.; Petryshen, Tracey L.; Posthuma, Danielle; Rietschel, Marcella; Riley, Brien P.; Rujescu, Dan; Sklar, Pamela; St Clair, David; Walters, James T. R.; Werge, Thomas; Siillivan, Patrick F.; O'Donovan, Michael C.; Scherer, Stephen W.; Neale, Benjamin M.; Sebat, Jonathan 分享 收藏
Inhibitors of Glycogen Synthase Kinase 3 with Exquisite Kinome-Wide Selectivity and Their Functional Effects Wagner, Florence F.; Bishop, Joshua A.; Gale, Jennifer P.; Shi, Xi; Walk, Michelle; Ketterman, Joshua; Patnaik, Debasis; Barker, Doug; Walpita, Deepika; Campbell, Arthur J.; Nguyen, Shannon; Lewis, Michael; Ross, Linda; Weiwer, Michel; An, W. Frank; Germain, Andrew R.; Nag, Partha P.; Metkar, Shailesh; Kaya, Taner; Dandapani, Sivaraman; Olson, David E.; Barbe, Anne-Laure; Lazzaro, Fanny; Sacher, Joshua R.; Cheah, Jaime H.; Fei, David; Perez, Jose; Munoz, Benito; Palmer, Michelle; Stegmaier, Kimberly; Schreiber, Stuart L.; Scolnick, Edward; Zhang, Yan-Ling; Haggarty, Stephen J.; Holson, Edward B.; Pan, Jen Q. 分享 收藏
Analysis of exome sequence in 604 trios for recessive genotypes in schizophrenia Rees, E.; Kirov, G.; Walters, J. T.; Richards, A. L.; Howrigan, D.; Kavanagh, D. H.; Pocklington, A. J.; Fromer, M.; Ruderfer, D. M.; Georgieva, L.; Carrera, N.; Gormley, P.; Palta, P.; Williams, H.; Dwyer, S.; Johnson, J. S.; Roussos, P.; Barker, D. D.; Banks, E.; Milanova, V.; Rose, S. A.; Chambert, K.; Mahajan, M.; Scolnick, E. M.; Moran, J. L.; Tsuang, M. T.; Glatt, S. J.; Chen, W. J.; Hwu, H-G; Neale, B. M.; Palotie, A.; Sklar, P.; Purcell, S. M.; McCarroll, S. A.; Holmans, P.; Owen, M. J.; O'Donovan, M. C. 分享 收藏
Kinetically selective inhibitors of histone deacetylase 2 (HDAC2) as cognition enhancers Wagner, F. F.; Zhang, Y. -L.; Fass, D. M.; Joseph, N.; Gale, J. P.; Weiwer, M.; McCarren, P.; Fisher, S. L.; Kaya, T.; Zhao, W. -N.; Reis, S. A.; Hennig, K. M.; Thomas, M.; Lemercier, B. C.; Lewis, M. C.; Guan, J. S.; Moyer, M. P.; Scolnick, E.; Haggarty, S. J.; Tsai, L. -H.; Holson, E. B. 分享 收藏
Copy number variation in schizophrenia in Sweden Szatkiewicz, J. P.; O'Dushlaine, C.; Chen, G.; Chambert, K.; Moran, J. L.; Neale, B. M.; Fromer, M.; Ruderfer, D.; Akterin, S.; Bergen, S. E.; Kaehler, A.; Magnusson, P. K. E.; Kim, Y.; Crowley, J. J.; Rees, E.; Kirov, G.; O'Donovan, M. C.; Owen, M. J.; Walters, J.; Scolnick, E.; Sklar, P.; Purcell, S.; Hultman, C. M.; McCarroll, S. A.; Sullivan, P. F. 分享 收藏
Genome-wide association analysis identifies 13 new risk loci for schizophrenia Ripke, Stephan; O'Dushlaine, Colm; Chambert, Kimberly; Moran, Jennifer L.; Kaehler, Anna K.; Akterin, Susanne; Bergen, Sarah E.; Collins, Ann L.; Crowley, James J.; Fromer, Menachem; Kim, Yunjung; Lee, Sang Hong; Magnusson, Patrik K. E.; Sanchez, Nick; Stahl, Eli A.; Williams, Stephanie; Wray, Naomi R.; Xia, Kai; Bettella, Francesco; Borglum, Anders D.; Bulik-Sullivan, Brendan K.; Cormican, Paul; Craddock, Nick; de Leeuw, Christiaan; Durmishi, Naser; Gill, Michael; Golimbet, Vera; Hamshere, Marian L.; Holmans, Peter; Hougaard, David M.; Kendler, Kenneth S.; Lin, Kuang; Morris, Derek W.; Mors, Ole; Mortensen, Preben B.; Neale, Benjamin M.; O'Neill, Francis A.; Owen, Michael J.; Milovancevic, Milica Pejovic; Posthuma, Danielle; Powell, John; Richards, Alexander L.; Riley, Brien P.; Ruderfer, Douglas; Rujescu, Dan; Sigurdsson, Engilbert; Silagadze, Teimuraz; Smit, August B.; Stefansson, Hreinn; Steinberg, Stacy; Suvisaari, Jaana; Tosato, Sarah; Verhage, Matthijs; Walters, James T.; Bramon, Elvira; Corvin, Aiden P.; O'Donovan, Michael C.; Stefansson, Kari; Scolnick, Edward; Purcell, Shaun; McCarroll, Steven A.; Sklar, Pamela; Hultman, Christina M.; Sullivan, Patrick F. 分享 收藏
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