Srinivasa Subramaniam - Publications, H-index & Citations

Srinivasa Subramaniam

Johns Hopkins University

30H指数

61论文数

8.8K被引数

收录论文 31

发表时间

Rhes, a striatal enriched protein, regulates post-translational small-ubiquitin-like-modifier (SUMO) modification of nuclear proteins and alters gene expression

CELLULAR AND MOLECULAR LIFE SCIENCES

IF6.2

2024-04-08

OAAI

Rivera, Oscar; Sharma, Manish; Dagar, Sunayana; Shahani, Neelam; Ramirez-Jarquin, Uri Nimrod; Crynen, Gogce; Karunadharma, Pabalu; McManus, Francis; Bonneil, Eric; Pierre, Thibault; Subramaniam, Srinivasa

Ribosome Profiling and Mass Spectrometry Reveal Widespread Mitochondrial Translation Defects in a Striatal Cell Model of Huntington Disease

MOLECULAR & CELLULAR PROTEOMICS

IF5.5

2024-04-01

OAAI

Dagar, Sunayana; Sharma, Manish; Tsaprailis, George; Tapia, Catherina Scharager; Crynen, Gogce; Joshi, Preksha Sandipkumar; Shahani, Neelam; Subramaniam, Srinivasa

SUMO modifies GβL and mediates mTOR signaling

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2024-04-01

OAAI

Park, Sophia Louise Lucille; Ramirez-Jarquin, Uri Nimrod; Shahani, Neelam; Rivera, Oscar; Sharma, Manish; Joshi, Preksha Sandipkumar; Hansalia, Aayushi; Dagar, Sunayana; McManus, Francis P.; Thibault, Pierre; Subramaniam, Srinivasa

Tunneling Nanotube: An Enticing Cell-Cell Communication in the Nervous System

BIOLOGY-BASEL

IF3.5

2023-09-27

OAAI

Dagar, Sunayana; Subramaniam, Srinivasa

Rhes protein transits from neuron to neuron and facilitates mutant huntingtin spreading in the brain

SCIENCE ADVANCES

IF12.5

2022-03-25

OAAI

Ramirez-Jarquin, Uri Nimrod; Sharma, Manish; Shahani, Neelam; Li, Yuqing; Boregowda, Siddaraju; Subramaniam, Srinivasa

Deletion of SUMO1 attenuates behavioral and anatomical deficits by regulating autophagic activities in Huntington disease

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2022-01-27

OAAI

Ramirez-Jarquin, Uri Nimrod; Sharma, Manish; Zhou, Wuyue; Shahani, Neelam; Subramaniam, Srinivasa

Ribosome traffic jam in neurodegeneration: decoding hurdles in Huntington disease

CELL STRESS

IF3

2021-06-14

OAAI

Subramaniam, Srinivasa

Mutant Huntingtin stalls ribosomes and represses protein synthesis in a cellular model of Huntington disease

NATURE COMMUNICATIONS

IF15.7

2021-03-05

OAAI

Eshraghi, Mehdi; Karunadharma, Pabalu P.; Blin, Juliana; Shahani, Neelam; Ricci, Emiliano P.; Michel, Audrey; Urban, Nicolai T.; Galli, Nicole; Sharma, Manish; Ramirez-Jarquin, Uri Nimrod; Florescu, Katie; Hernandez, Jennifer; Subramaniam, Srinivasa

The mammalian target of rapamycin (mTOR) kinase mediates haloperidol-induced cataleptic behavior

TRANSLATIONAL PSYCHIATRY

IF6.2

2020-10-02

OAAI

Ramirez-Jarquin, Uri Nimrod; Shahani, Neelam; Pryor, William; Usiello, Alessandro; Subramaniam, Srinivasa

Cyclic GMP-AMP synthase promotes the inflammatory and autophagy responses in Huntington disease 环gmp-amp合酶促进亨廷顿病的炎症和自噬反应

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2020-06-24

OAAI

Sharma, Manish; Rajendrarao, Sumitha; Shahani, Neelam; Ramirez-Jarquin, Uri Nimrod; Subramaniam, Srinivasa

RasGRP1 is a causal factor in the development of L-DOPA-induced dyskinesia in Parkinson's disease

SCIENCE ADVANCES

IF12.5

2020-05-01

OAAI

Eshraghi, Mehdi; Ramirez-Jarquin, Uri Nimrod; Shahani, Neelam; Nuzzo, Tommaso; De Rosa, Arianna; Swarnkar, Supriya; Galli, Nicole; Rivera, Oscar; Tsaprailis, George; Scharager-Tapia, Catherina; Crynen, Gogce; Li, Qin; Thiolat, Marie-Laure; Bezard, Erwan; Usiello, Alessandro; Subramaniam, Srinivasa

Rhes Tunnels: A Radical New Way of Communication in the Brain's Striatum?

BIOESSAYS

IF2.7

2020-04-01

OAAI

Subramaniam, Srinivasa

Exaggerated mitophagy: a weapon of striatal destruction in the brain?

BIOCHEMICAL SOCIETY TRANSACTIONS

IF4.3

2020-03-04

OAAI

Subramaniam, Srinivasa

Rhes, a striatal-enriched protein, promotes mitophagy via Nix

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2019-11-01

OAAI

Sharma, Manish; Jarquin, Uri Nimrod Ramirez; Rivera, Oscar; Kazantzis, Melissa; Eshraghi, Mehdi; Shahani, Neelam; Sharma, Vishakha; Tapia, Ricardo; Subramaniam, Srinivasa

Forebrain depletion of Rheb GTPase elicits spatial memory deficits in mice

NEUROBIOLOGY OF AGING

IF3.5

2017-02-01

OAAI

Shahani, Neelam; Huang, Wen-Chin; Varnum, Megan; Page, Damon T.; Subramaniam, Srinivasa

RasGRP1 promotes amphetamine-induced motor behavior through a Rhes interaction network (Rhesactome) in the striatum

SCIENCE SIGNALING

IF6.6

2016-11-15

OAAI

Shahani, Neelam; Swarnkar, Supriya; Giovinazzo, Vincenzo; Morgenweck, Jenny; Bohn, Laura M.; Scharager-Tapia, Catherina; Pascal, Bruce; Martinez-Acedo, Pablo; Khare, Kshitij; Subramaniam, Srinivasa

Ectopic expression of the striatal-enriched GTPase Rhes elicits cerebellar degeneration and an ataxia phenotype in Huntington's disease

NEUROBIOLOGY OF DISEASE

IF5.6

2015-10-01

PREAI

Swarnkar, Supriya; Chen, Youjun; Pryor, William M.; Shahani, Neelam; Page, Damon T.; Subramaniam, Srinivasa

Rheb Inhibits Protein Synthesis by Activating the PERK-eIF2α Signaling Cascade

CELL REPORTS

IF6.9

2015-02-01

OAAI

Tyagi, Richa; Shahani, Neelam; Gorgen, Lindsay; Ferretti, Max; Pryor, William; Chen, Po Yu; Swarnkar, Supriya; Worley, Paul F.; Karbstein, Katrin; Snyder, Solomon H.; Subramaniam, Srinivasa

Huntingtin promotes mTORC1 signaling in the pathogenesis of Huntington's disease

SCIENCE SIGNALING

IF6.6

2014-10-28

PREAI

Pryor, William M.; Biagioli, Marta; Shahani, Neelam; Swarnkar, Supriya; Huang, Wen-Chin; Page, Damon T.; MacDonald, Marcy E.; Subramaniam, Srinivasa

DISC1 regulates trafficking and processing of APP and Aβ generation DISC1规范APP和a β 生成的贩运和处理

MOLECULAR PSYCHIATRY

IF10.1

2014-09-16

OAAI

Shahani, N.; Seshadri, S.; Jaaro-Peled, H.; Ishizuka, K.; Hirota-Tsuyada, Y.; Wang, Q.; Koga, M.; Sedlak, T. W.; Korth, C.; Brandon, N. J.; Kamiya, A.; Subramaniam, S.; Tomoda, T.; Sawa, A.

研究方向