Ralf Ficner - Publications, H-index & Citations

Ralf Ficner

georg-august universität göttingen

55H指数

312论文数

9.1K被引数

收录论文 85

发表时间

New structures of human formylglycine-generating enzyme reveal features important for catalysis, disease and structure-based drug design 人类甲酰甘氨酸生成酶的新结构揭示了与催化、疾病及基于结构的药物设计相关的关键特征

Journal of Molecular Biology

IF4.5

2026-08-11

OAAI

Julia L. Kowal; Sarfaraz Alam; Karthikeyan Radhakrishnan; Achim Dickmanns; Piotr Neumann; Lars Schlotawa; Ralf Ficner; Thomas Dierks; Markus G. Rudolph; Hartmut H. Niemann

Molecular basis for the interactions of eIF2β with eIF5, eIF2B, and 5MP1 and their regulation by CK2 eIF2β与eIF5、eIF2B和5MP1相互作用的分子基础及其受CK2的调控

RNA

IF5

2025-10-01

PREAI

Wagner, Paul A.; Song, Meimei; Doran, Paul; Seker, Aysenur; Ficner, Ralf; Kuhle, Bernhard; Marintchev, Assen

Chemical crosslinking extends and complements UV crosslinking in analysis of RNA/DNA nucleic acid-protein interaction sites by mass spectrometry Welp, L.M.; Wulf, A.; Chernev, A.; Horokhovskyi, Y.; Moshkovskii, S.; Dybkov, O.; Neumann, P.; Pašen, M.; Siraj, A.; Raabe, M.; et al. 化学交联在质谱分析RNA/DNA核苷酸-蛋白质相互作用位点方面扩展并补充了UV交联。Nucleic Acids Res. 2025, 53, gkaf727. [Google Scholar] [CrossRef]

NUCLEIC ACIDS RESEARCH

IF13.1

2025-08-28

OAAI

Welp, Luisa M.; Wulf, Alexander; Chernev, Aleksandar; Horokhovskyi, Yehor; Moshkovskii, Sergei; Dybkov, Olexandr; Neumann, Piotr; Pasen, Martin; Siraj, Arslan; Raabe, Monika; Goethert, Henri; Walshe, James L.; Infante, Deliana A.; Schwarzer, Ana C. de A. P.; Dickmanns, Achim; Johannsson, Sven; Schmitzova, Jana; Wohlgemuth, Ingo; Netz, Eugen; He, Yi; Fritzemeier, Kai; Delanghe, Bernard; Viner, Rosa; Vos, Seychelle M.; Oberbeckmann, Elisa; Bohnsack, Katherine E.; Bohnsack, Markus T.; Cramer, Patrick; Ficner, Ralf; Kohlbacher, Oliver; Liepe, Juliane; Sachsenberg, Timo; Urlaub, Henning

The previously uncharacterized RnpM (YlxR) protein modulates the activity of ribonuclease P in Bacillus subtilis in vitro

NUCLEIC ACIDS RESEARCH

IF13.1

2023-12-05

OAAI

Wicke, Dennis; Neumann, Piotr; Goessringer, Markus; Chernev, Aleksandar; Davydov, Swetlana; Poehlein, Anja; Daniel, Rolf; Urlaub, Henning; Hartmann, Roland K.; Ficner, Ralf; Stuelke, Joerg

Fungal COP9 signalosome assembly requires connection of two trimeric intermediates for integration of intrinsic deneddylase

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2023-08-21

OAAI

Bakti, Fruzsina; Stupperich, Helena; Schmitt, Kerstin; Valerius, Oliver; Koehler, Anna M.; Meister, Cindy; Strohdiek, Anja; Harting, Rebekka; Sasse, Christoph; Heimel, Kai; Neumann, Piotr; Ficner, Ralf; Braus, Gerhard H.

Ornithine is the central intermediate in the arginine degradative pathway and its regulation in Bacillus subtilis

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2023-07-01

OAAI

Warneke, Robert; Garbers, Tim Benedict; Herzberg, Christina; Aschenbrandt, Georg; Ficner, Ralf; Stuelke, Joerg

Conformational dynamics of the RNA binding channel regulates loading and translocation of the DEAH-box helicase Prp43

NUCLEIC ACIDS RESEARCH

IF13.1

2023-05-11

OAAI

Enders, Marieke; Ficner, Ralf; Adio, Sarah

Regulation of the DEAH/RHA helicase Prp43 by the G-patch factor Pfa1

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2022-11-21

OAAI

Enders, Marieke; Ficner, Ralf; Adio, Sarah

Structural basis for c-di-AMP-dependent regulation of the bacterial stringent response by receptor protein DarB

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2022-07-01

OAAI

Heidemann, Jana L.; Neumann, Piotr; Krueger, Larissa; Wicke, Dennis; Vinhoven, Liza; Linden, Andreas; Dickmanns, Achim; Stuelke, Joerg; Urlaub, Henning; Ficner, Ralf

Mapping protein interactions in the active TOM-TIM23 supercomplex

NATURE COMMUNICATIONS

IF15.7

2021-09-29

OAAI

Gomkale, Ridhima; Linden, Andreas; Neumann, Piotr; Schendzielorz, Alexander Benjamin; Stoldt, Stefan; Dybkov, Olexandr; Kilisch, Markus; Schulz, Christian; Cruz-Zaragoza, Luis Daniel; Schwappach, Blanche; Ficner, Ralf; Jakobs, Stefan; Urlaub, Henning; Rehling, Peter

Structural and functional insights into human tRNA guanine transgylcosylase

RNA BIOLOGY

IF3.4

2021-07-31

OAAI

Sievers, Katharina; Welp, Luisa; Urlaub, Henning; Ficner, Ralf

Structural model of the M7G46 Methyltransferase TrmB in complex with tRNA M7G46甲基转移酶TrmB与tRNA复合物的结构模型

RNA BIOLOGY

IF3.4

2021-05-19

OAAI

Blersch, Katharina F.; Burchert, Jan-Philipp; August, Sophie-Charlotte; Welp, Luisa; Neumann, Piotr; Koester, Sarah; Urlaub, Henning; Ficner, Ralf

A meet-up of two second messengers: the c-di-AMP receptor DarB controls (p)ppGpp synthesis in Bacillus subtilis

NATURE COMMUNICATIONS

IF15.7

2021-02-22

OAAI

Krueger, Larissa; Herzberg, Christina; Wicke, Dennis; Baehre, Heike; Heidemann, Jana L.; Dickmanns, Achim; Schmitt, Kerstin; Ficner, Ralf; Stuelke, Joerg

OpenPepXL: An Open-Source Tool for Sensitive Identification of Cross-Linked Peptides in XL-MS

MOLECULAR & CELLULAR PROTEOMICS

IF5.5

2020-12-01

OAAI

Netz, Eugen; Dijkstra, Tjeerd M. H.; Sachsenberg, Timo; Zimmermann, Lukas; Walzer, Mathias; Monecke, Thomas; Ficner, Ralf; Dybkov, Olexandr; Urlaub, Henning; Kohlbacher, Oliver

Defining the architecture of the human TIM22 complex by chemical crosslinking

FEBS LETTERS

IF3

2020-11-13

OAAI

Valpadashi, Anusha; Callegari, Sylvie; Linden, Andreas; Neumann, Piotr; Ficner, Ralf; Urlaub, Henning; Deckers, Markus; Rehling, Peter

Crystal structure of the Rab33B/Atg16L1 effector complex

SCIENTIFIC REPORTS

IF3.9

2020-07-31

OAAI

Metje-Sprink, Janina; Groffmann, Johannes; Neumann, Piotr; Barg-Kues, Brigitte; Ficner, Ralf; Kuehnel, Karin; Schalk, Amanda M.; Binotti, Beyenech

A Cross-linking Mass Spectrometry Approach Defines Protein Interactions in Yeast Mitochondria

MOLECULAR & CELLULAR PROTEOMICS

IF5.5

2020-07-01

OAAI

Linden, Andreas; Deckers, Markus; Parfentev, Iwan; Pflanz, Ralf; Homberg, Bettina; Neumann, Piotr; Ficner, Ralf; Rehling, Peter; Urlaub, Henning

Atg21 organizes Atg8 lipidation at the contact of the vacuole with the phagophore

AUTOPHAGY

IF14.3

2020-06-09

OAAI

Munzel, Lena; Neumann, Piotr; Otto, Florian B.; Krick, Roswitha; Metje-Sprink, Janina; Kroppen, Benjamin; Karedla, Narain; Enderlein, Joerg; Meinecke, Michael; Ficner, Ralf; Thumm, Michael

Structural analysis of the intrinsically disordered splicing factor Spp2 and its binding to the DEAH-box ATPase Prp2

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2020-01-23

OAAI

Hamann, Florian; Schmitt, Andreas; Favretto, Filippo; Hofele, Romina; Neumann, Piotr; Xiang, ShengQi; Urlaub, Henning; Zweckstetter, Markus; Ficner, Ralf

Crystal structures of the c-di-AMP-synthesizing enzyme CdaA

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2019-07-01

OAAI

Heidemann, Jana L.; Neumann, Piotr; Dickmanns, Achim; Ficner, Ralf

研究方向