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Multi-modal analysis of human hepatic stellate cells identifies novel therapeutic targets for metabolic dysfunction-associated steatotic liver disease 多模态分析人类肝星状细胞鉴定出代谢功能障碍相关脂肪性肝病的新的治疗靶点 Kim, Hyun Young; Rosenthal, Sara Brin; Liu, Xiao; Miciano, Charlene; Hou, Xiaomeng; Miller, Michael; Buchanan, Justin; Poirion, Olivier B.; Chilin-Fuentes, Daisy; Han, Cuijuan; Housseini, Mojgan; Weber, Raquel Carvalho-Gontijo; Lee, Wonseok; Zhao, Huayi; Diggle, Karin; Preissl, Sebastian; Glass, Christopher K.; Ren, Bing; Wang, Allen; Brenner, David A.; Kisseleva, Tatiana 分享 收藏
Enhlink infers distal and context-specific enhancer-promoter linkages Enhlink推断远端和上下文特异性增强子-启动子连接 Poirion, Olivier B.; Zuo, Wulin; Spruce, Catrina; Baker, Candice N.; Daigle, Sandra L.; Olson, Ashley; Skelly, Daniel A.; Chesler, Elissa J.; Baker, Christopher L.; White, Brian S. 分享 收藏
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Human microglia maturation is underpinned by specific gene regulatory networks Han, Claudia Z.; Li, Rick Z.; Hansen, Emily; Trescott, Samantha; Fixsen, Bethany R.; Nguyen, Celina T.; Mora, Cristina M.; Spann, Nathanael J.; Bennett, Hunter R.; Poirion, Olivier; Buchanan, Justin; Warden, Anna S.; Xia, Bing; Schlachetzki, Johannes C. M.; Pasillas, Martina P.; Preissl, Sebastian; Wang, Allen; O'Connor, Carolyn; Shriram, Shreya; Kim, Roy; Schafer, Danielle; Ramirez, Gabriela; Challacombe, Jean; Anavim, Samuel A.; Johnson, Avalon; Gupta, Mihir; Glass, Ian A.; Birth Defects Res Lab, Birth Defects Research; Levy, Michael L.; Ben Haim, Sharona; Gonda, David D.; Laurent, Louise; Hughes, Jennifer F.; Page, David C.; Blurton-Jones, Mathew; Glass, Christopher K.; Coufal, Nicole G. 分享 收藏
Robust enhancer-gene regulation identified by single-cell transcriptomes and epigenomes Xie, Fangming; Armand, Ethan J.; Yao, Zizhen; Liu, Hanqing; Bartlett, Anna; Behrens, M. Margarita; Li, Yang Eric; Lucero, Jacinta D.; Luo, Chongyuan; Nery, Joseph R.; Pinto-Duarte, Antonio; Poirion, Olivier B.; Preissl, Sebastian; Rivkin, Angeline C.; Tasic, Bosiljka; Zeng, Hongkui; Ren, Bing; Ecker, Joseph R.; Mukamel, Eran A. 分享 收藏
Human-gained heart enhancers are associated with species-specific cardiac attributes (sep, 10.1038/s44161-022-00124-7, 2022) Destici, Eugin; Zhu, Fugui; Tran, Shaina; Preissl, Sebastian; Farah, Elie N.; Zhang, Yanxiao; Hou, Xiameng; Poirion, Olivier B.; Lee, Ah Young; Grinstein, Jonathan D.; Bloomekatz, Joshua; Kim, Hong Sook; Hu, Robert; Evans, Sylvia M.; Ren, Bing; Benner, Chris; Chi, Neil C. 分享 收藏
Human-gained heart enhancers are associated with species-specific cardiac attributes Destici, Eugin; Zhu, Fugui; Tran, Shaina; Preissl, Sebastian; Farah, Elie N.; Zhang, Yanxiao; Hou, Xiameng; Poirion, Olivier B.; Lee, Ah Young; Grinstein, Jonathan D.; Bloomekatz, Joshua; Kim, Hong Sook; Hu, Robert; Evans, Sylvia M.; Ren, Bing; Benner, Chris; Chi, Neil C. 分享 收藏
GranatumX: A Community-Engaging, Modularized, and Flexible Webtool for Single-Cell Data Analysis Garmire, David G.; Zhu, Xun; Mantravadi, Aravind; Huang, Qianhui; Yunits, Breck; Liu, Yu; Wolfgruber, Thomas; Poirion, Olivier; Zhao, Tianying; Arisdakessian, Cedric; Stanojevic, Stefan; Garmire, Lana X. 分享 收藏
Cardiac cell type-specific gene regulatory programs and disease risk association 心脏细胞类型特异性基因调控程序和疾病风险关联 Hocker, James D.; Poirion, Olivier B.; Zhu, Fugui; Buchanan, Justin; Zhang, Kai; Chiou, Joshua; Wang, Tsui-Min; Zhang, Qingquan; Hou, Xiaomeng; Li, Yang E.; Zhang, Yanxiao; Farah, Elie N.; Wang, Allen; McCulloch, Andrew D.; Gaulton, Kyle J.; Ren, Bing; Chi, Neil C.; Preissl, Sebastian 分享 收藏
Single-cell meta-analysis of SARS-CoV-2 entry genes across tissues and demographics 跨组织和人口统计学的SARS-CoV-2进入基因的单细胞荟萃分析 Muus, Christoph; Luecken, Malte D.; Eraslan, Gokcen; Sikkema, Lisa; Waghray, Avinash; Heimberg, Graham; Kobayashi, Yoshihiko; Vaishnav, Eeshit Dhaval; Subramanian, Ayshwarya; Smillie, Christopher; Jagadeesh, Karthik A.; Duong, Elizabeth Thu; Fiskin, Evgenij; Triglia, Elena Torlai; Ansari, Meshal; Cai, Peiwen; Lin, Brian; Buchanan, Justin; Chen, Sijia; Shu, Jian; Haber, Adam L.; Chung, Hattie; Montoro, Daniel T.; Adams, Taylor; Aliee, Hananeh; Allon, Samuel J.; Andrusivova, Zaneta; Angelidis, Ilias; Ashenberg, Orr; Bassler, Kevin; Becavin, Christophe; Benhar, Inbal; Bergenstrahle, Joseph; Bergenstrahle, Ludvig; Bolt, Liam; Braun, Emelie; Bui, Linh T.; Callori, Steven; Chaffin, Mark; Chichelnitskiy, Evgeny; Chiou, Joshua; Conlon, Thomas M.; Cuoco, Michael S.; Cuomo, Anna S. E.; Deprez, Marie; Duclos, Grant; Fine, Denise; Fischer, David S.; Ghazanfar, Shila; Gillich, Astrid; Giotti, Bruno; Gould, Joshua; Guo, Minzhe; Gutierrez, Austin J.; Habermann, Arun C.; Harvey, Tyler; He, Peng; Hou, Xiaomeng; Hu, Lijuan; Hu, Yan; Jaiswal, Alok; Ji, Lu; Jiang, Peiyong; Kapellos, Theodoros S.; Kuo, Christin S.; Larsson, Ludvig; Leney-Greene, Michael A.; Lim, Kyungtae; Litvinukova, Monika; Ludwig, Leif S.; Lukassen, Soeren; Luo, Wendy; Maatz, Henrike; Madissoon, Elo; Mamanova, Lira; Manakongtreecheep, Kasidet; Leroy, Sylvie; Mayr, Christoph H.; Mbano, Ian M.; McAdams, Alexi M.; Nabhan, Ahmad N.; Nyquist, Sarah K.; Penland, Lolita; Poirion, Olivier B.; Poli, Sergio; Qi, CanCan; Queen, Rachel; Reichart, Daniel; Rosas, Ivan; Schupp, Jonas C.; Shea, Conor, V; Shi, Xingyi; Sinha, Rahul; Sit, Rene, V; Slowikowski, Kamil; Slyper, Michal; Smith, Neal P.; Sountoulidis, Alex; Strunz, Maximilian; Sullivan, Travis B.; Sun, Dawei; Talavera-Lopez, Carlos; Tan, Peng; Tantivit, Jessica; Travaglini, Kyle J.; Tucker, Nathan R.; Vernon, Katherine A.; Wadsworth, Marc H.; Waldman, Julia; Wang, Xiuting; Xu, Ke; Yan, Wenjun; Zhao, William; Ziegler, Carly G. K. 分享 收藏
The MUC5B-associated variant rs35705950 resides within an enhancer subject to lineage- and disease-dependent epigenetic remodeling Gally, Fabienne; Sasse, Sarah K.; Kurche, Jonathan S.; Gruca, Margaret A.; Cardwell, Jonathan H.; Okamoto, Tsukasa; Chu, Hong W.; Hou, Xiaomeng; Poirion, Olivier B.; Buchanan, Justin; Preissl, Sebastian; Ren, Bing; Colgan, Sean P.; Dowell, Robin D.; Yang, Ivana, V; Schwartz, David A.; Gerber, Anthony N. 分享 收藏
Single-cell multiomic profiling of human lungs reveals cell-type-specific and age-dynamic control of SARS-CoV2 host genes 人肺的单细胞多组谱分析揭示了SARS-CoV2宿主基因的细胞类型特异性和年龄动态控制 Wang, Allen; Chiou, Joshua; Poirion, Olivier B.; Buchanan, Justin; Valdez, Michael J.; Verheyden, Jamie M.; Hou, Xiaomeng; Kudtarkar, Parul; Narendra, Sharvari; Newsome, Jacklyn M.; Guo, Minzhe; Faddah, Dina A.; Zhang, Kai; Young, Randee E.; Barr, Justinn; Sajti, Eniko; Misra, Ravi; Huyck, Heidie; Rogers, Lisa; Poole, Cory; Whitsett, Jeffery A.; Pryhuber, Gloria; Xu, Yan; Gaulton, Kyle J.; Preissl, Sebastian; Sun, Xin 分享 收藏
Single-cell chromatin accessibility maps reveal regulatory programs driving early mouse organogenesis Pijuan-Sala, Blanca; Wilson, Nicola K.; Xia, Jun; Hou, Xiaomeng; Hannah, Rebecca L.; Kinston, Sarah; Calero-Nieto, Fernando J.; Poirion, Olivier; Preissl, Sebastian; Liu, Feng; Gottgens, Berthold 分享 收藏
Understanding breast cancer using a developmental perspective Wahl, G. M.; Ma, Z.; Chung, C.; Dravis, C.; Spike, B. T.; Giraddi, R. T.; Balcioglu, O.; Fan, C.; Hagos, B.; Heinz, R.; Herrera-Valdez, J.; Hou, X.; Hwang, J.; Lasken, R.; Luna, G.; Lytle, N. E.; Mehrabad, E. M.; Novotny, M.; Perou, C. M.; Poirion, O.; Preissl, S.; Ren, B.; Reya, T.; Trejo, C. L.; Varley, K. T. 分享 收藏
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Single-Cell Chromatin Analysis of Mammary Gland Development Reveals Cell-State Transcriptional Regulators and Lineage Relationships Chung, Chi-Yeh; Ma, Zhibo; Dravis, Christopher; Preissl, Sebastian; Poirion, Olivier; Luna, Gidsela; Hou, Xiaomeng; Giraddi, Rajshekhar R.; Ren, Bing; Wahl, Geoffrey M. 分享 收藏
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