Brian J. Bacskai - Publications, H-index & Citations

Brian J. Bacskai

harvard medical school

82H指数

280论文数

2.5W被引数

收录论文 121

发表时间

Compartment-specific analysis reveals disrupted astrocytic calcium transients in anesthetized Alzheimer's disease mice 亚室特异性分析揭示了麻醉阿尔茨海默病小鼠中星形胶质细胞钙瞬变的紊乱

JOURNAL OF ALZHEIMERS DISEASE

IF3.1

2026-06-30

PREAI

Md Joynal Abedin; Yee Fun Lee; Melinda Zhang; Alyssa N Russ; Dmitry Gerashchenko; Brian J. Bacskai; Ksenia V. Kastanenka

Role of dysregulated calcium homeostasis in astrocytes in neurodegenerative disorders 星形胶质细胞钙稳态失调在神经退行性疾病中的作用

Nature Reviews Neuroscience

IF26.7

2026-03-26

PREAI

Maria V. Sanchez-Mico; Maria Calvo-Rodriguez; Brian J. Bacskai

Age-associated T cell immunity decreases circulating endothelial progenitor cells

Stem Cells

IF3.6

2025-10-23

PREAI

Fang Zhang; Qiuchen Zhao; Shuzhen Guo; Gen Hamanaka; Dong-Bin Back; Shin Ishikane; Ester Licastro; Ji-Hyun Park; Wenlu Li; Elga Esposito; Ksenia V Kastanenka; Brian J Bacskai; Kazuhide Hayakawa

Journal of Cerebral Blood Flow & Metabolism

IF0

2025-09-08

OAAI

Marion Giraud; Dae Hee Yun; Leon P Munting; Kwanghun Chung; Brian J Bacskai; Steven M Greenberg; Matthew P Frosch; Alain Goriely; Susanne J van Veluw; Sylvie Lorthois

Vasomotion loss precedes impaired cerebrovascular reactivity and microbleeds in cerebral amyloid angiopathy 血管运动丧失先于脑淀粉样血管病的脑血管反应性受损和微出血。

BRAIN COMMUNICATIONS

IF4.5

2025-05-14

OAAI

Kozberg, Mariel G.; Munting, Leon P.; Hanlin, Lee H.; Auger, Corinne A.; van den Berg, Maarten L.; de Senneville, Baudouin Denis; Hirschler, Lydiane; Warnking, Jan M.; Barbier, Emmanuel L.; Farrar, Christian T.; Greenberg, Steven M.; Bacskai, Brian J.; van Veluw, Susanne J.

Optogenetic targeting of cortical astrocytes selectively improves NREM sleep in an Alzheimer's disease mouse model 皮质星形胶质细胞的光遗传学靶向选择性改善阿尔茨海默病小鼠模型中的NREM睡眠

SCIENTIFIC REPORTS

IF3.9

2024-10-04

OAAI

Zhao, Qiuchen; Yokomizo, Shinya; Perle, Stephen J.; Lee, Yee Fun; Zhou, Heng; Miller, Morgan R.; Li, Hanyan; Gerashchenko, Dmitry; Gomperts, Stephen N.; Bacskai, Brian J.; Kastanenka, Ksenia V.

Recording γ-secretase activity in living mouse brains

ELIFE

IF0

2024-10-03

OAAI

Hou, Steven S.; Ikegawa, Yuya; Kwon, Yeseo; Wieckiewicz, Natalia; Houser, Mei C. Q.; Lundin, Brianna; Bacskai, Brian J.; Berezovska, Oksana; Maesako, Masato

Instability of excitatory synapses in experimental autoimmune encephalomyelitis and the outcome for excitatory circuit inputs to individual cortical neurons

BRAIN BEHAVIOR AND IMMUNITY

IF7.6

2024-07-01

OAAI

Gillani, Rebecca L.; Kironde, Eseza N.; Whiteman, Sara; Zwang, Theodore J.; Bacskai, Brian J.

NB-02 Protects Neurons and Astrocytes from Oligomeric Amyloid-β-Mediated Damage

JOURNAL OF ALZHEIMERS DISEASE

IF3.1

2024-05-14

PREAI

Miller, Morgan R.; Lariviere, Lavender; Pagnier, Guillaume J.; Aygar, Sema; Wieckiewicz, Natalia; Maesako, Masato; Bacskai, Brian J.; Kastanenka, Ksenia V.

Real-time imaging of mitochondrial redox reveals increased mitochondrial oxidative stress associated with amyloid β aggregates in vivo in a mouse model of Alzheimer's disease

MOLECULAR NEURODEGENERATION

IF17.5

2024-01-18

OAAI

Calvo-Rodriguez, Maria; Kharitonova, Elizabeth K.; Snyder, Austin C.; Hou, Steven S.; Sanchez-Mico, Maria Virtudes; Das, Sudeshna; Fan, Zhanyun; Shirani, Hamid; Nilsson, K. Peter R.; Serrano-Pozo, Alberto; Bacskai, Brian J.

Sleep restoration by optogenetic targeting of GABAergic neurons reprograms microglia and ameliorates pathological phenotypes in an Alzheimer's disease model 通过gaba能神经元的光遗传学靶向恢复睡眠在阿尔茨海默病模型中重新编程小胶质细胞并改善病理表型

MOLECULAR NEURODEGENERATION

IF17.5

2023-12-01

OAAI

Zhao, Qiuchen; Maci, Megi; Miller, Morgan R.; Zhou, Heng; Zhang, Fang; Algamal, Moustafa; Lee, Yee Fun; Hou, Steven S.; Perle, Stephen J.; Le, Hoang; Russ, Alyssa N.; Lo, Eng H.; Gerashchenko, Dmitry; Gomperts, Stephen N.; Bacskai, Brian J.; Kastanenka, Ksenia V.

Optogenetic targeting of astrocytes restores slow brain rhythm function and slows Alzheimer's disease pathology 星形胶质细胞的光遗传学靶向恢复缓慢的脑节律功能并减缓阿尔茨海默氏病的病理

SCIENTIFIC REPORTS

IF3.9

2023-08-11

OAAI

Lee, Yee Fun; Russ, Alyssa N.; Zhao, Qiuchen; Perle, Stephen J.; Maci, Megi; Miller, Morgan R.; Hou, Steven S.; Algamal, Moustafa; Zhao, Zhuoyang; Li, Hanyan; Gelwan, Noah; Liu, Zhe; Gomperts, Stephen N.; Araque, Alfonso; Galea, Elena; Bacskai, Brian J.; Kastanenka, Ksenia V.

Near-infrared fluorescence lifetime imaging of amyloid-β aggregates and tau fibrils through the intact skull of mice

NATURE BIOMEDICAL ENGINEERING

IF26.6

2023-02-06

OAAI

Hou, Steven S. S.; Yang, Joyce; Lee, Jeong Heon; Kwon, Yeseo; Calvo-Rodriguez, Maria; Bao, Kai; Ahn, Sung; Kashiwagi, Satoshi; Kumar, Anand T. N.; Bacskai, Brian J.; Choi, Hak Soo

Spontaneous vasomotion propagates along pial arterioles in the awake mouse brain like stimulus-evoked vascular reactivity

JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

IF4.5

2023-01-19

OAAI

Munting, Leon P.; Bonnar, Orla; Kozberg, Mariel G.; Auger, Corinne A.; Hirschler, Lydiane; Hou, Steven S.; Greenberg, Steven M.; Bacskai, Brian J.; van Veluw, Susanne J.

Reduced excitatory neuron activity and interneuron-type-specific deficits in a mouse model of Alzheimer's disease

COMMUNICATIONS BIOLOGY

IF5.1

2022-12-02

OAAI

Algamal, Moustafa; Russ, Alyssa N. N.; Miller, Morgan R. R.; Hou, Steven S. S.; Maci, Megi; Munting, Leon P. P.; Zhao, Qiuchen; Gerashchenko, Dmitry; Bacskai, Brian J. J.; Kastanenka, Ksenia V. V.

Accelerated amyloid angiopathy and related vascular alterations in a mixed murine model of Alzheimer′s disease and type two diabetes

FLUIDS AND BARRIERS OF THE CNS

IF6.2

2022-11-07

OAAI

Vargas-Soria, Maria; Jose Ramos-Rodriguez, Juan; del Marco, Angel; Hierro-Bujalance, Carmen; Jose Carranza-Naval, Maria; Calvo-Rodriguez, Maria; van Veluw, Susanne J.; Stitt, Alan W.; Simo, Rafael; Bacskai, Brian J.; Infante-Garcia, Carmen; Garcia-Alloza, Monica

Low frequency visual stimulation enhances slow wave activity without disrupting the sleep pattern in mice

SCIENTIFIC REPORTS

IF3.9

2022-07-19

OAAI

Thankachan, Stephen; Yang, Chun; Kastanenka, Ksenia, V; Bacskai, Brian J.; Gerashchenko, Dmitry

Effects of cerebral amyloid angiopathy on the brain vasculome

AGING CELL

IF7.1

2022-07-18

OAAI

Deng, Wenjun; Guo, Shuzhen; van Veluw, Susanne J.; Yu, Zhanyang; Chan, Su Jing; Takase, Hajime; Arai, Ken; Ning, MingMing; Greenberg, Steven M.; Lo, Eng H.; Bacskai, Brian J.

Corpus callosum lesions are associated with worse cognitive performance in cerebral amyloid angiopathy

BRAIN COMMUNICATIONS

IF4.5

2022-04-26

OAAI

Freeze, Whitney M.; Zanon Zotin, Maria Clara; Scherlek, Ashley A.; Perosa, Valentina; Auger, Corinne A.; Warren, Andrew D.; van der Weerd, Louise; Schoemaker, Dorothee; Horn, Mitchell J.; Gurol, M. Edip; Gokcal, Elif; Bacskai, Brian J.; Viswanathan, Anand; Greenberg, Steven M.; Reijmer, Yael D.; van Veluw, Susanne J.

Histopathology of Cerebral Microinfarcts and Microbleeds in Spontaneous Intracerebral Hemorrhage

TRANSLATIONAL STROKE RESEARCH

IF4.3

2022-04-06

OAAI

Jolink, Wilmar M. T.; van Veluw, Susanne J.; Zwanenburg, Jaco J. M.; Rozemuller, Annemieke J. M.; van Hecke, Wim; Frosch, Matthew P.; Bacskai, Brian J.; Rinkel, Gabriel J. E.; Greenberg, Steven M.; Klijn, Catharina J. M.

研究方向