Dimitri Krainc - Publications, H-index & Citations

Dimitri Krainc

Northwestern University

70H指数

206论文数

2.5W被引数

收录论文 126

发表时间

Is SORL1 a common genetic target across neurodegenerative diseases? A multi-ancestry biobank study SORL1是否是神经退行性疾病中常见的遗传靶点？一项多祖先来源生物银行研究

Brain

IF11.7

2026-05-26

OAAI

Marzieh Khani; Sheila N Yeboah; Catalina Cerquera-Cleves; Alexandra Kedmi; Bernabe I Bustos; Spencer M Grant; Suleyman Can Akerman; Fulya Akçimen; Paul Suhwan Lee; Paula Reyes-Pérez; Lara M Lange; Hampton Leonard; Mathew J Koretsky; Mary B Makarious; Zachary Schneider; Caroline Jonson; Pin-Shiuan Chen; Yi Wen Tay; Jeffrey D Rothstein; Chin-Hsien Lin; Shen-Yang Lim; Christine Klein; Kalpana Merchant; Niccolò E Mencacci; Dimitri Krainc; Mark R Cookson; Andrew Singleton; Sara Bandres-Ciga

Genome-wide association study of copy number variations in Parkinson’s disease 帕金森病中全基因组拷贝数变异的关联研究

npj Parkinson's Disease

IF8.2

2026-04-20

OAAI

Zied Landoulsi; Ashwin Ashok Kumar Sreelatha; Nicole Kuznetsov; Claudia Schulte; Dheeraj Reddy Bobbili; Ludovica Montanucci; Costin Leu; Lisa-Marie Niestroj; Emadeldin Hassanin; Cloé Domenighetti; Pierre-Emmanuel Sugier; Milena Radivojkov-Blagojevic; Peter Lichtner; Berta Portugal; Connor Edsall; Jens Krüger; Dena G. Hernandez; Cornelis Blauwendraat; George D. Mellick; Alexander Zimprich; Walter Pirker; Manuela Tan; Ekaterina Rogaeva; Anthony Lang; Sulev Koks; Pille Taba; Suzanne Lesage; Alexis Brice; Jean-Christophe Corvol; Marie-Christine Chartier-Harlin; Eugenie Mutez; Kathrin Brockmann; Angela B. Deutschländer; Georges M. Hadjigeorgiou; Efthimos Dardiotis; Leonidas Stefanis; Athina Maria Simitsi; Enza Maria Valente; Simona Petrucci; Letizia Straniero; Anna Zecchinelli; Gianni Pezzoli; Laura Brighina; Carlo Ferrarese; Grazia Annesi; Andrea Quattrone; Monica Gagliardi; Lena F. Burbulla; Hirotaka Matsuo; Akiyoshi Nakayama; Nobutaka Hattori; Kenya Nishioka; Sun Ju Chung; Yun Joong Kim; Lukas Pavelka; Pierre Kolber; Bart PC van de Warrenburg; Bastiaan R. Bloem; Andrew B. Singleton; Dan Vitale; Mathias Toft; Lasse Pihlstrom; Leonor Correia Guedes; Joaquim J. Ferreira; Soraya Bardien; Jonathan Carr; Eduardo Tolosa; Mario Ezquerra; Pau Pastor; Karin Wirdefeldt; Nancy L. Pedersen; Caroline Ran; Andrea C. Belin; Andreas Puschmann; Carl E. Clarke; Karen E. Morrison; Dimitri Krainc; Matt J. Farrer; Dennis Lal; Alexis Elbaz; Thomas Gasser; Rejko Krüger; Manu Sharma; Patrick May

Author Correction: Neuroprotective role of Sirt1 in mammalian models of Huntington’s disease through activation of multiple Sirt1 targets 作者更正：Sirt1在哺乳动物亨廷顿病模型中的神经保护作用是通过激活多种Sirt1靶点实现的。

Nature Medicine

IF50

2025-11-26

PREAI

Mali Jiang; Jiawei Wang; Jinrong Fu; Lin Du; Hyunkyung Jeong; Tim West; Lan Xiang; Qi Peng; Zhipeng Hou; Huan Cai; Tamara Seredenina; Nicolas Arbez; Shanshan Zhu; Katherine Sommers; Jennifer Qian; Jiangyang Zhang; Susumu Mori; X William Yang; Kellie L K Tamashiro; Susan Aja; Timothy H Moran; Ruth Luthi-Carter; Bronwen Martin; Stuart Maudsley; Mark P Mattson; Robert H Cichewicz; Christopher A Ross; David M Holtzman; Dimitri Krainc; Wenzhen Duan

Adult-Onset BPAN: An Atypical Presentation Mimicking Early-Onset Parkinson's Disease 成人发病型BPAN：一种模拟早发型帕金森病的非典型表现

Movement Disorders Clinical Practice

IF2.7

2025-08-23

OAAI

Mariana H.G. Monje MD, PhD; Padmaja Vittal MD; Ignacio Juan Keller Sarmiento MD; Lisa Kinsley CGC; Dimitri Krainc MD, PhD; Niccolò E. Mencacci MD, PhD

The Spectrum of Neurologic Phenotypes Associated With NUS1 Pathogenic Variants: A Comprehensive Case Series 与NUS1致病性变异相关的神经表型谱：一项综合性病例系列研究

Annals of Neurology

IF7.7

2025-07-01

OAAI

Sarah M. Brooker MD, PhD; Maria Novelli MD; Robert Coukos PhD; Neha Prakash MBBS; Walaa A. Kamel MD; Marta Amengual-Gual MD; Mathieu Anheim MD, PhD; Giulia Barcia MD, PhD; Tanya Bardakjian MS; Franciska Baur MD; Steffen Berweck MD; Bigna K. Bölsterli MD; Melanie Brugger MD; Thomas Cassini MD; Nicolas Chatron MD; Brian Corner MS; Hormos Salimi Dafsari MD; Jean-Madeleine de Sainte Agathe MD; Colin A. Ellis MD; Kimberly M. Ezell APRN, FNP; Cendrine Foucard MD; Steven J. Frucht MD; Maria C. Garcia MBBS; Deepak Gill MBBS, FRACP; Anne Guimier MD; Rizwan Hamid MD, PhD; Damià Heine-Suñer PhD; Peter Herkenrath MD; Marie Hully MD; Ioannis U. Isaias MD, PhD; Louis Januel MD; Chloe Laurencin MD; Taylor Laut MS; Alinoe Lavillaureix MD; Gaetan Lesca MD, PhD; Marion Lesieur-Sebellin MD; Luca Magistrelli MD, PhD; Cecilia Marelli MD, PhD; Heather C. Mefford MD, PhD; Bryce A. Mendelsohn MD; Saadet Mercimek-Andrews MD, PhD; Claire Miller MD, PhD; Shekeeb S. Mohammad MBBS, PhD, FRACP; Francesca Morgante MD, PhD; Sirisha Nandipati MD; Thomas Opladen MD; Mahesh Padmanaban MD; Micaela Pauni MD; Gianni Pezzoli MD; Amelie Piton PhD; Francis Ramond MD, PhD; Giulietta M. Riboldi MD, PhD; Christelle Rougeot-Jung MD; Fernando Santos-Simarro MD, PhD; Ingrid E. Scheffer MBBS, PhD; Naoual Serari M2; Christine M. Stahl MD; Ann Stembridge Kung MS; Susana Tarongí Sanchez MD; Christel Thauvin-Robinet MD, PhD; Marianne Till MD; Christine Tranchant MD, PhD; Christopher Troedson MBBS, FRACP; Thomas F. Tropea DO, MPH; Olivier Vanakker MD, PhD; Patricia Vega MD; Maxi Leona Wiese MD; Udo Wieshmann MD, PhD, FRCP; Laura J. Williams MB BCh BAO, MD; Thomas Wirth MD; Michael Zech MD; Hans Zempel MD, PhD; Emmanuel Roze MD, PhD; Vincenzo Leuzzi MD; Serena Galosi MD, PhD; Victor S. C. Fung PhD, FRACP; Gemma Carvill PhD; Dimitri Krainc MD, PhD; Elizabeth Gerard MD; Niccolò E. Mencacci MD, PhD

Novel In-Frame FGF14 Deletion Causes Spinocerebellar Ataxia Type 27A: Clinical Response to Deep Brain Stimulation and 4-Aminopyridine 新型同框FGF14缺失导致脊髓小脑共济失调27A型：对深部脑刺激和4-氨基吡啶的临床反应

Movement Disorders

IF7.6

2025-03-29

OAAI

Ignacio J. Keller Sarmiento MD; Roberta Bovenzi MD; Morgan Kinsinger; Lisa Kinsley MS; Bernabe I. Bustos PhD; Dimitri Krainc MD, PhD; Niccolò E. Mencacci MD, PhD

The role of parkin in monkey

PROTEIN & CELL

IF12.8

2024-11-13

OAAI

Song, Pingping; Krainc, Dimitri

Association of Body Mass Index and Parkinson Disease A Bidirectional Mendelian Randomization Study 体重指数与帕金森病的关系 -- 双向孟德尔随机化研究

NEUROLOGY

IF8.5

2024-08-13

PREAI

Domenighetti, Cloe; Sugier, Pierre-Emmanuel; Ashok Kumar Sreelatha, Ashwin; Schulte, Claudia; Grover, Sandeep; Portugal, Berta; Lee, Pei-Chen; May, Patrick; Bobbili, Dheeraj; Radivojkov Blagojevic, Milena; Lichtner, Peter; Singleton, Andrew B.; Hernandez, Dena; Edsall, Connor; Mellick, George D.; Zimprich, Alexander A.; Pirker, Walter; Rogaeva, Ekaterina A.; Lang, Anthony E.; Koks, Sulev; Taba, Pille; Lesage, Suzanne; Brice, Alexis; Corvol, Jean-Christophe; Chartier-Harlin, Marie-Christine; Mutez, Eugenie; Brockmann, Kathrin; Deutschlander, Angela B.; Hadjigeorgiou, Georgios M.; Dardiotis, Efthimios; Stefanis, Leonidas; Simitsi, Athina Maria; Valente, Enza Maria; Petrucci, Simona; Straniero, Letizia; Zecchinelli, Anna L.; Pezzoli, Gianni; Brighina, Laura; Ferrarese, Carlo; Annesi, Grazia; Quattrone, Andrea; Gagliardi, Monica; Matsuo, Hirotaka; Nakayama, Akiyoshi; Hattori, Nobutaka; Nishioka, Kenya; Chung, Sun Ju; Kim, Yun Joong; Kolber, Pierre; Van De Warrenburg, Bart P. C.; Bloem, Bastiaan R.; Toft, Mathias; Pihlstrm, Lasse; Correia Guedes, Leonor; Ferreira, Joaquim J.; Bardien, Soraya; Carr, Jonathan; Tolosa, Eduardo; Ezquerra, Mario; Pastor, Pau; Diez-Fairen, Monica; Wirdefeldt, Karin; Pedersen, Nancy L.; Ran, Caroline; Belin, Andrea C.; Puschmann, Andreas; Hellberg, Clara; Clarke, Carl E.; Morrison, Karen E.; Tan, Manuela M.; Krainc, Dimitri; Burbulla, Lena F.; Farrer, Matthew; Kruger, Rejko; Gasser, Thomas; Sharma, Manu; Elbaz, Alexis

Diverse Functions of Parkin in Midbrain Dopaminergic Neurons Parkin在中脑多巴胺能神经元中的多种功能

MOVEMENT DISORDERS

IF7.6

2024-06-10

OAAI

Song, Pingping; Krainc, Dimitri

Key genes and convergent pathogenic mechanisms in Parkinson disease

NATURE REVIEWS NEUROSCIENCE

IF26.7

2024-04-10

PREAI

Coukos, Robert; Krainc, Dimitri

Twelve Years of Drug Prioritization to Help Accelerate Disease Modification Trials in Parkinson's Disease: The International Linked Clinical Trials Initiative 十二年的药物优先次序，以帮助加速帕金森病的疾病改善试验: 国际链接临床试验倡议

JOURNAL OF PARKINSONS DISEASE

IF5

2024-04-05

OAAI

Wyse, Richard K.; Isaacs, Tom; Barker, Roger A.; Cookson, Mark R.; Dawson, Ted M.; Devos, David; Dexter, David T.; Duffen, Joy; Federoff, Howard; Fiske, Brian; Foltynie, Thomas; Fox, Susan; Greenamyre, J. Timothy; Kieburtz, Karl; Kordower, Jeffrey H.; Krainc, Dimitri; Matthews, Helen; Moore, Darren J.; Mursaleen, Leah; Schwarzschild, Michael A.; Stott, Simon R. W.; Sulzer, David; Svenningsson, Per; Tanner, Caroline M.; Carroll, Camille; Simon, David K.; Brundin, Patrik

De novo FRMD5 Missense Variants in Patients with Childhood-Onset Ataxia, Prominent Nystagmus, and Seizures

MOVEMENT DISORDERS

IF7.6

2024-04-04

OAAI

Sarmiento, Ignacio J. Keller; Bustos, Bernabe I.; Blackburn, Joanna; Hac, Nicholas E. F.; Ruzhnikov, Maura; Monroe, Matthea; Levy, Rebecca J.; Kinsley, Lisa; Li, Megan; Silani, Vincenzo; Lubbe, Steven J.; Krainc, Dimitri; Mencacci, Niccolo E.

Alterations in Blood Methylome as Potential Epigenetic Biomarker in Sporadic Parkinson's Disease

ANNALS OF NEUROLOGY

IF7.7

2024-04-02

OAAI

Gonzalez-Latapi, Paulina; Bustos, Bernabe; Dong, Siyuan; Lubbe, Steven; Simuni, Tanya; Krainc, Dimitri

Fostering Academia-Industry Partnerships to Facilitate Therapeutic Discoveries in Neurology: The Role of ANA as a Catalyst

ANNALS OF NEUROLOGY

IF7.7

2024-03-04

PREAI

Ross, M. Elizabeth; Krainc, Dimitri; Guo, Ming; Mouradian, M. Maral; Ratan, Rajiv R.

A GNAI1 Pathogenic Variant in a Case with GNAO1-Isolated Dystonia: A Modifier of Disease Severity?GNAO1-Isolated肌张力障碍患者的一种snai1致病变异: 疾病严重程度的修饰因子？

MOVEMENT DISORDERS

IF7.6

2024-02-28

OAAI

Monje, Mariana H. G.; Blackburn, Joanna Sarah; Kinsley, Lisa; Krainc, Dimitri; Mencacci, Niccolo E.

VPS13C regulates phospho-Rab10-mediated lysosomal function in human dopaminergic neurons

JOURNAL OF CELL BIOLOGY

IF6.4

2024-02-15

OAAI

Schroeder, Leonie F.; Peng, Wesley; Gao, Ge; Wong, Yvette C.; Schwake, Michael; Krainc, Dimitri

Inhibition of cysteine protease cathepsin Lincreases the level and activity of lysosomal glucocerebrosidase

JCI INSIGHT

IF6.1

2024-02-08

OAAI

Kim, Myung Jong; Kim, Soojin; Reinheckel, Thomas; Krainc, Dimitri

Parkinson's disease-linked parkin mutation disrupts recycling of synaptic vesicles in human dopaminergic neurons

NEURON

IF15

2023-12-01

PREAI

Song, Pingping; Peng, Wesley; Sauve, Veronique; Fakih, Rayan; Xie, Zhong; Ysselstein, Daniel; Krainc, Talia; Wong, Yvette C.; Mencacci, Niccolo E.; Savas, Jeffrey N.; Surmeier, D. James; Gehring, Kalle; Krainc, Dimitri

Shifting the trajectory of therapeutic development for neurological and psychiatric disorders

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2023-11-01

PREAI

Krainc, Dimitri; Martin, William J.; Casey, Bradford; Jensen, Frances E.; Tishkoff, Sarah; Potter, William Z.; Hyman, Steven E.

Misregulation of mitochondria- lysosome contact dynamics in Charcot- Marie-Tooth Type 2B disease Rab7 mutant sensory peripheral neurons Charcot-marie-tooth 2B型疾病Rab7突变体感觉外周神经元中线粒体-溶酶体接触动力学的错误调节

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2023-10-25

OAAI

Wong, Yvette C.; Jayaraj, Nirupa D.; Belton, Tayler B.; Shum, George C.; Ball, Hannah E.; Ren, Dongjun; Tadenev, Abigail L. D.; Krainc, Dimitri; Burgess, Robert W.; Menichella, Daniela M.

研究方向