未登录 分享 收藏
Application of new approach methodologies for nonclinical safety assessment of drug candidates 新方法学在药物候选物非临床安全性评估中的应用 Beilmann, Mario; Adkins, Karissa; Boonen, Harrie C. M.; Hewitt, Philip; Hu, Wenyue; Mader, Robert; Moore, Susanne; Rana, Payal; Steger-Hartmann, Thomas; Villenave, Remi; van Vleet, Terry 分享 收藏
分享 收藏
PretoxTM: a text mining system for extracting treatment-related findings from preclinical toxicology reports Corvi, Javier; Diaz-Roussel, Nicolas; Fernandez, Jose M.; Ronzano, Francesco; Centeno, Emilio; Accuosto, Pablo; Ibrahim, Celine; Asakura, Shoji; Bringezu, Frank; Frohlicher, Mirjam; Kreuchwig, Annika; Nogami, Yoko; Rih, Jeong; Rodriguez-Esteban, Raul; Sajot, Nicolas; Wichard, Joerg; Wu, Heng-Yi Michael; Drew, Philip; Steger-Hartmann, Thomas; Valencia, Alfonso; Furlong, Laura I.; Capella-Gutierrez, Salvador 分享 收藏
分享 收藏
分享 收藏
分享 收藏
The evolving role of investigative toxicology in the pharmaceutical industry Pognan, Francois; Beilmann, Mario; Boonen, Harrie C. M.; Czich, Andreas; Dear, Gordon; Hewitt, Philip; Mow, Tomas; Oinonen, Teija; Roth, Adrian; Steger-Hartmann, Thomas; Valentin, Jean-Pierre; Van Goethem, Freddy; Weaver, Richard J. J.; Newham, Peter 分享 收藏
The eTRANSAFE Project on Translational Safety Assessment through Integrative Knowledge Management: Achievements and Perspectives Pognan, Francois; Steger-Hartmann, Thomas; Diaz, Carlos; Blomberg, Niklas; Bringezu, Frank; Briggs, Katharine; Callegaro, Giulia; Capella-Gutierrez, Salvador; Centeno, Emilio; Corvi, Javier; Drew, Philip; Drewe, William C.; Fernandez, Jose M.; Furlong, Laura I.; Guney, Emre; Kors, Jan A.; Mayer, Miguel Angel; Pastor, Manuel; Pinero, Janet; Ramirez-Anguita, Juan Manuel; Ronzano, Francesco; Rowell, Philip; Sauch-Pitarch, Josep; Valencia, Alfonso; van de Water, Bob; van der Lei, Johan; van Mulligen, Erik; Sanz, Ferran 分享 收藏
分享 收藏
Setting the stage for next-generation risk assessment with non-animal approaches: the EU-ToxRisk project experience Mone, M. J.; Pallocca, G.; Escher, S. E.; Exner, T.; Herzler, M.; Bennekou, S. Hougaard; Kamp, H.; Kroese, E. D.; Leist, Marcel; Steger-Hartmann, T.; van de Water, B. 分享 收藏
New ideas for non-animal approaches to predict repeated-dose systemic toxicity: Report from an EPAA Blue Sky Workshop Mahony, Catherine; Ashton, Randolph S.; Birk, Barbara; Boobis, Alan R.; Cull, Tom; Daston, George P.; Ewart, Lorna; Knudsen, Thomas B.; Manou, Irene; Maurer-Stroh, Sebastian; Margiotta-Casaluci, Luigi; Muller, Boris P.; Nordlund, Par; Roberts, Ruth A.; Steger-Hartmann, Thomas; Vandenbossche, Evita; Viant, Mark R.; Vinken, Mathieu; Whelan, Maurice; Zvonimir, Zvonar; Cronin, Mark T. D. 分享 收藏
Evaluation of EGFR induced on-target and target-mediated adverse effects in a 3D human lung tumour/skin microphysiological coculture system Huebner, Juliane; Raschke, Marian; Schimek, Katharina; Ruetschle, Isabel; Graessle, Sarah; Schnurre, Susanne; Lauster, Roland; Maschmeyer, Ilka; Steger-Hartmann, Thomas; Marx, Uwe 分享 收藏
Prediction of human drug-induced liver injury (DILI) in relation to oral doses and blood concentrations Albrecht, Wiebke; Kappenberg, Franziska; Brecklinghaus, Tim; Stoeber, Regina; Marchan, Rosemarie; Zhang, Mian; Ebbert, Kristina; Kirschner, Hendrik; Grinberg, Marianna; Leist, Marcel; Moritz, Wolfgang; Cadenas, Cristina; Ghallab, Ahmed; Reinders, Joerg; Vartak, Nachiket; van Thriel, Christoph; Golka, Klaus; Tolosa, Laia; Castell, Jose V.; Damm, Georg; Seehofer, Daniel; Lampen, Alfonso; Braeuning, Albert; Buhrke, Thorsten; Behr, Anne-Cathrin; Oberemm, Axel; Gu, Xiaolong; Kittana, Naim; van de Water, Bob; Kreiling, Reinhard; Fayyaz, Susann; van Aerts, Leon; Smedsrod, Bard; Ellinger-Ziegelbauer, Heidrun; Steger-Hartmann, Thomas; Gundert-Remy, Ursula; Zeigerer, Anja; Ullrich, Anett; Runge, Dieter; Lee, Serene M. L.; Schiergens, Tobias S.; Kuepfer, Lars; Aguayo-Orozco, Alejandro; Sachinidis, Agapios; Edlund, Karolina; Gardner, Iain; Rahnenfuehrer, Joerg; Hengstler, Jan G. 分享 收藏
Simultaneous evaluation of anti-EGFR-induced tumour and adverse skin effects in a microfluidic human 3D co-culture model Huebner, Juliane; Raschke, Marian; Ruetschle, Isabel; Graessle, Sarah; Hasenberg, Tobias; Schirrmann, Kerstin; Lorenz, Alexandra; Schnurre, Susanne; Lauster, Roland; Maschmeyer, Ilka; Steger-Hartmann, Thomas; Marx, Uwe 分享 收藏
分享 收藏
Making reliable negative predictions of human skin sensitisation using an in silico fragmentation approach 使用计算机碎片方法对人类皮肤致敏做出可靠的负面预测 Chilton, Martyn L.; Macmillan, Donna S.; Steger-Hartmann, Thomas; Hillegass, Jedd; Bellion, Phillip; Vuorinen, Anna; Etter, Sylvain; Smith, Benjamin P. C.; White, Angela; Sterchele, Paul; De Smedt, Ann; Glogovac, Milica; Glowienke, Susanne; O'Brien, Devin; Parakhia, Rahul 分享 收藏
分享 收藏
分享 收藏
分享 收藏
.png){kind=icon}
未登录.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
