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收藏Polymodal K+ channel modulation contributes to dual analgesic and anti-inflammatory actions of traditional botanical medicines
Manville, Rian W.; Yoshimura, Ryan F.; Yeromin, Andriy V.; Hogenkamp, Derk; van der Horst, Jennifer; Zavala, Angel; Chinedu, Sonia; Arena, Grey; Lasky, Emma; Fisher, Mark; Tracy, Christopher R.; Othy, Shivashankar; Jepps, Thomas A.; Cahalan, Michael D.; Abbott, Geoffrey W.
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收藏Gene expression and functional deficits underlie TREM2-knockout microglia responses in human models of Alzheimer's disease (vol 11, 5370, 2020)
McQuade, Amanda; Kang, You Jung; Hasselmann, Jonathan; Jairaman, Amit; Sotelo, Alexandra; Coburn, Morgan; Shabestari, Sepideh Kiani; Chadarevian, Jean Paul; Fote, Gianna; Tu, Christina H.; Danhash, Emma; Silva, Jorge; Martinez, Eric; Cotman, Carl; Prieto, G. Aleph; Thompson, Leslie M.; Steffan, Joan S.; Smith, Ian; Davtyan, Hayk; Cahalan, Michael; Cho, Hansang; Blurton-Jones, Mathew
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收藏Early stress-induced impaired microglial pruning of excitatory synapses on immature CRH-expressing neurons provokes aberrant adult stress responses
Bolton, Jessica L.; Short, Annabel K.; Othy, Shivashankar; Kooiker, Cassandra L.; Shao, Manlin; Gunn, Benjamin G.; Beck, Jaclyn; Bai, Xinglong; Law, Stephanie M.; Savage, Julie C.; Lambert, Jeremy J.; Belelli, Delia; Tremblay, Marie-Eve; Cahalan, Michael D.; Baram, Tallie Z.
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收藏The P522R protective variant of PLCG2 promotes the expression of antigen presentation genes by human microglia in an Alzheimer's disease mouse model
Claes, Christel; England, Whitney E.; Danhash, Emma P.; Shabestari, Sepideh Kiani; Jairaman, Amit; Chadarevian, Jean Paul; Hasselmann, Jonathan; Tsai, Andy P.; Coburn, Morgan A.; Sanchez, Jessica; Lim, Tau En; Hidalgo, Jorge L. S.; Tu, Christina; Cahalan, Michael D.; Lamb, Bruce T.; Landreth, Gary E.; Spitale, Robert C.; Blurton-Jones, Mathew; Davtyan, Hayk
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收藏Piezo1 channels restrain regulatory T cells but are dispensable for effector CD4+ T cell responses
Jairaman, Amit; Othy, Shivashankar; Dynes, Joseph L.; Yeromin, Andriy, V; Zavala, Angel; Greenberg, Milton L.; Nourse, Jamison L.; Holt, Jesse R.; Cahalan, Stuart M.; Marangoni, Francesco; Parker, Ian; Pathak, Medha M.; Cahalan, Michael D.
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收藏Mechanically activated ion channel Piezo1 modulates macrophage polarization and stiffness sensing机械激活的离子通道压电1调节巨噬细胞极化和刚度传感
Atcha, Hamza; Jairaman, Amit; Holt, Jesse R.; Meli, Vijaykumar S.; Nagalla, Raji R.; Veerasubramanian, Praveen Krishna; Brumm, Kyle T.; Lim, Huy E.; Othy, Shivashankar; Cahalan, Michael D.; Pathak, Medha M.; Liu, Wendy F.
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收藏Gene expression and functional deficits underlie TREM2-knockout microglia responses in human models of Alzheimer's disease在阿尔茨海默氏病的人类模型中,基因表达和功能缺陷是TREM2-knockout小胶质细胞反应的基础
McQuade, Amanda; Kang, You Jung; Hasselmann, Jonathan; Jairaman, Amit; Sotelo, Alexandra; Coburn, Morgan; Shabestari, Sepideh Kiani; Chadarevian, Jean Paul; Fote, Gianna; Tu, Christina H.; Danhash, Emma; Silva, Jorge; Martinez, Eric; Cotman, Carl; Prieto, G. Aleph; Thompson, Leslie M.; Steffan, Joan S.; Smith, Ian; Davtyan, Hayk; Cahalan, Michael; Cho, Hansang; Blurton-Jones, Mathew
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收藏Regulatory T cells suppress Th17 cell Ca2+ signaling in the spinal cord during murine autoimmune neuroinflammation
Othy, Shivashankar; Jairaman, Amit; Dynes, Joseph L.; Dong, Tobias X.; Tune, Cornelia; Yeromin, Andriy, V; Zavala, Angel; Akunwafo, Chijioke; Chen, Fangyi; Parker, Ian; Cahalan, Michael D.
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收藏Regulatory T cells promote remyelination in the murine experimental autoimmune encephalomyelitis model of multiple sclerosis following human neural stem cell transplant
McIntyre, Laura L.; Greilach, Scott A.; Othy, Shivashankar; Sears-Kraxberger, Ilse; Wi, Brian; Ayala-Angulo, Julio; Vu, Estelle; Pham, Quan; Silva, Jorge; Dang, Kody; Rezk, Fady; Steward, Oswald; Cahalan, Michael D.; Lane, Thomas E.; Walsh, Craig M.
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收藏LOCAL CRAC CHANNEL BLOCKADE TREATS COLITIS IN MICE
Skupsky, Jonathan; Hwang, Michael; Zavala, Angel; Nakasaki, Manando; Sabui, Subrata; Said, Hamid; Cahalan, Michael; Newman, Andrew; Ransom, John; Greenberg, Milton L.
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收藏Intermittent Ca2+ signals mediated by Orail regulate basal T cell motility
Donglt, Tobias X.; Othylt, Shivashankar; Greenberg, Milton L.; Jairaman, Amit; Akunwafo, Chijioke; Leverrier, Sabrina; Yu, Ying; Parkerl, Ian; Dynes, Joseph L.; Cahalan, Michael D.
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