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收藏Anti-human TLR7 antibody for therapeutic intervention in systemic lupus erythematosus抗人TLR7抗体用于系统性红斑狼疮的疗法干预
Fukui, Ryutaro; Murakami, Yusuke; Kanno, Atsuo; Motoi, Yuji; Manno, Atsushi; Honda, Tomohiro; Yamada, Shinnosuke; Ishiguro, Jun; Kagari, Takashi; Nakamura, Kensuke; Kadokura, Michinori; Isobe, Takashi; Tomimori, Yoshiaki; Tanaka, Jun; Senaldi, Giorgio; Shimizu, Toshiyuki; Miyake, Kensuke 分享 收藏 Clonal hematopoiesis-related mutant ASXL1 promotes atherosclerosis in mice via dysregulated innate immunitySato, Naru; Goyama, Susumu; Chang, Yu-Hsuan; Miyawaki, Masashi; Fujino, Takeshi; Koide, Shuhei; Denda, Tamami; Liu, Xiaoxiao; Ueda, Koji; Yamamoto, Keita; Asada, Shuhei; Takeda, Reina; Yonezawa, Taishi; Tanaka, Yosuke; Honda, Hiroaki; Ota, Yasunori; Shibata, Takuma; Sekiya, Motohiro; Isobe, Tomoya; Lamagna, Chrystelle; Masuda, Esteban; Iwama, Atsushi; Shimano, Hitoshi; Inoue, Jun-ichiro; Miyake, Kensuke; Kitamura, Toshio 分享 收藏 TNF-α exacerbates SARS-CoV-2 infection by stimulating CXCL1 production from macrophagesKobayashi, Moe; Kobayashi, Nene; Deguchi, Kyoka; Omori, Seira; Nagai, Minami; Fukui, Ryutaro; Song, Isaiah; Fukuda, Shinji; Miyake, Kensuke; Ichinohe, Takeshi 分享 收藏 分享 收藏 A stress sensor, IRE1a, is required for bacterial-exotoxin-induced interleukin-1b production in tissue-resident macrophagesSasaki, Izumi; Fukuda-Ohta, Yuri; Nakai, Chihiro; Wakaki-Nishiyama, Naoko; Okamoto, Chizuyo; Okuzaki, Daisuke; Morita, Shuhei; Kaji, Shiori; Furuta, Yuki; Hemmi, Hiroaki; Kato, Takashi; Yamamoto, Asumi; Tosuji, Emi; Saitoh, Shin-Ichiroh; Tanaka, Takashi; Hoshino, Katsuaki; Fukuda, Shinji; Miyake, Kensuke; Kuroda, Etsushi; Ishii, Ken J.; Iwawaki, Takao; Furukawa, Koichi; Kaisho, Tsuneyasu 分享 收藏 TLR7/8 stress response drives histiocytosis in SLC29A3 disordersTLR7/8应激反应驱动SLC29A3疾病中的组织细胞增生症Shibata, Takuma; Sato, Ryota; Taoka, Masato; Saitoh, Shin-Ichiroh; Komine, Mayumi; Yamaguchi, Kiyoshi; Goyama, Susumu; Motoi, Yuji; Kitaura, Jiro; Izawa, Kumi; Yamauchi, Yoshio; Tsukamoto, Yumiko; Ichinohe, Takeshi; Fujita, Etsuko; Hiranuma, Ryosuke; Fukui, Ryutaro; Furukawa, Yoichi; Kitamura, Toshio; Takai, Toshiyuki; Tojo, Arinobu; Ohtsuki, Mamitaro; Ohto, Umeharu; Shimizu, Toshiyuki; Ozawa, Manabu; Yoshida, Nobuaki; Isobe, Toshiaki; Latz, Eicke; Mukai, Kojiro; Taguchi, Tomohiko; Hemmi, Hiroaki; Akira, Shizuo; Miyake, Kensuke 分享 收藏 分享 收藏 STING signalling is terminated through ESCRT-dependent microautophagy of vesicles originating from recycling endosomesSTING信号通过ESCRT依赖性的源自再循环内体的囊泡微自噬终止Kuchitsu, Yoshihiko; Mukai, Kojiro; Uematsu, Rei; Takaada, Yuki; Shinojima, Ayumi; Shindo, Ruri; Shoji, Tsumugi; Hamano, Shiori; Ogawa, Emari; Sato, Ryota; Miyake, Kensuke; Kato, Akihisa; Kawaguchi, Yasushi; Nishitani-Isa, Masahiko; Izawa, Kazushi; Nishikomori, Ryuta; Yasumi, Takahiro; Suzuki, Takehiro; Dohmae, Naoshi; Uemura, Takefumi; Barber, Glen N. N.; Arai, Hiroyuki; Waguri, Satoshi; Taguchi, Tomohiko 分享 收藏 TLR3 forms a laterally aligned multimeric complex along double-stranded RNA for efficient signal transductionTLR3沿着双链RNA形成横向排列的多聚体复合物，用于有效的信号转导Sakaniwa, Kentaro; Fujimura, Akiko; Shibata, Takuma; Shigematsu, Hideki; Ekimoto, Toru; Yamamoto, Masaki; Ikeguchi, Mitsunori; Miyake, Kensuke; Ohto, Umeharu; Shimizu, Toshiyuki 分享 收藏 IMPDH inhibition activates TLR-VCAM1 pathway and suppresses the development of MLL-fusion leukemia抑制IMPDH激活TLR-VCAM1通路并抑制MLL融合白血病的发展Liu, Xiaoxiao; Sato, Naru; Yabushita, Tomohiro; Li, Jingmei; Jia, Yuhan; Tamura, Moe; Asada, Shuhei; Fujino, Takeshi; Fukushima, Tsuyoshi; Yonezawa, Taishi; Tanaka, Yosuke; Fukuyama, Tomofusa; Tsuchiya, Akiho; Shikata, Shiori; Iwamura, Hiroyuki; Kinouchi, Chieko; Komatsu, Kensuke; Yamasaki, Satoshi; Shibata, Tatsuhiro; Sasaki, Atsuo T.; Schibler, Janet; Wunderlich, Mark; O'Brien, Eric; Mizukawa, Benjamin; Mulloy, James C.; Sugiura, Yuki; Takizawa, Hitoshi; Shibata, Takuma; Miyake, Kensuke; Kitamura, Toshio; Goyama, Susumu 分享 收藏 Genetic dissection of TLR9 reveals complex regulatory and cryptic proinflammatory roles in mouse lupusLeibler, Claire; John, Shinu; Elsner, Rebecca A.; Thomas, Kayla B.; Smita, Shuchi; Joachim, Stephen; Levack, Russell C.; Callahan, Derrick J.; Gordon, Rachael A.; Bastacky, Sheldon; Fukui, Ryutaro; Miyake, Kensuke; Gingras, Sebastien; Nickerson, Kevin M.; Shlomchik, Mark J. 分享 收藏 分享 收藏 Role of the Orphan Transporter SLC35E1 in the Nuclear Egress of Herpes Simplex Virus 1孤儿转运蛋白SLC35E1在单纯疱疹病毒1核出口中的作用Maeda, Fumio; Kato, Akihisa; Takeshima, Kosuke; Shibazaki, Misato; Sato, Ryota; Shibata, Takuma; Miyake, Kensuke; Kozuka-Hata, Hiroko; Oyama, Masaaki; Shimizu, Eigo; Imoto, Seiya; Miyano, Satoru; Adachi, Shungo; Natsume, Tohru; Takeuchi, Koh; Maruzuru, Yuhei; Koyanagi, Naoto; Jun, Arii; Yasushi, Kawaguchi 分享 收藏 Anti-TLR7 Antibody Protects Against Lupus Nephritis in NZBWF1 Mice by Targeting B Cells and Patrolling MonocytesMurakami, Yusuke; Fukui, Ryutaro; Tanaka, Reika; Motoi, Yuji; Kanno, Atsuo; Sato, Ryota; Yamaguchi, Kiyoshi; Amano, Hirofumi; Furukawa, Yoichi; Suzuki, Hitoshi; Suzuki, Yusuke; Tamura, Naoto; Yamashita, Naomi; Miyake, Kensuke 分享 收藏 分享 收藏 分享 收藏 TRPM5 Negatively Regulates Calcium-Dependent Responses in Lipopolysaccharide-Stimulated B LymphocytesSakaguchi, Taiki; Okumura, Ryu; Ono, Chisato; Okuzaki, Daisuke; Kawai, Takafumi; Okochi, Yoshifumi; Tanimura, Natsuko; Murakami, Mari; Kayama, Hisako; Umemoto, Eiji; Kioka, Hidetaka; Ohtani, Tomohito; Sakata, Yasushi; Miyake, Kensuke; Okamura, Yasushi; Baba, Yoshihiro; Takeda, Kiyoshi 分享 收藏 Activated M2 Macrophages Contribute to the Pathogenesis of IgG4-Related Disease via Toll-Like Receptor 7/Interleukin-33 Signaling活化的M2巨噬细胞通过Toll样受体7/Interleukin-33信号参与IgG4-Related疾病的发病机制Ishiguro, Noriko; Moriyama, Masafumi; Furusho, Katsuhiro; Furukawa, Sachiko; Shibata, Takuma; Murakami, Yusuke; Chinju, Akira; Haque, A. S. M. Rafiul; Gion, Yuka; Ohta, Miho; Maehara, Takashi; Tanaka, Akihiko; Yamauchi, Masaki; Sakamoto, Mizuki; Mochizuki, Keita; Ono, Yuko; Hayashida, Jun-Nosuke; Sato, Yasuharu; Kiyoshima, Tamotsu; Yamamoto, Hidetaka; Miyake, Kensuke; Nakamura, Seiji 分享 收藏 分享 收藏 
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