未登录 分享 收藏
Sphingosine-1-phosphate phosphohydrolase regulates endoplasmic reticulurn-to-Golgi trafficking of ceramide Giussani, Paola; Maceyka, Michael; Le Stunff, Herve; Mikami, Aki; Lepine, Sandrine; Wang, Elaine; Kelly, Samuel; Merrill, Alfred H., Jr.; Milstien, Sheldon; Spiegel, Sarah 分享 收藏
The S1P2 receptor negatively regulates platelet-derived growth factor-induced motility and proliferation Goparaju, SK; Jolly, PS; Watterson, KR; Bektas, M; Alvarez, S; Sarkar, S; Mel, L; Ishii, I; Chun, J; Milstien, S; Spiegel, S 分享 收藏
Neutrophilia in severe asthma is reduced in Ormdl3 overexpressing mice James, Briana N.; Weigel, Cynthia; Green, Christopher D.; Brown, Ryan D. R.; Palladino, Elisa N. D.; Tharakan, Anuj; Milstien, Sheldon; Proia, Richard L.; Martin, Rebecca K.; Spiegel, Sarah 分享 收藏
Sphingosine Kinase 2 in Stromal Fibroblasts Creates a Hospitable Tumor Microenvironment in Breast Cancer Weigel, Cynthia; Maczis, Melissa A.; Palladino, Elisa N. D.; Green, Christopher D.; Maceyka, Michael; Guo, Chunqing; Wang, Xiang-Yang; Dozmorov, Mikhail G.; Milstien, Sheldon; Spiegel, Sarah 分享 收藏
Ceramide in apoptosis and oxidative stress in allergic inflammation and asthma 神经酰胺在变应性炎症和哮喘中的细胞凋亡和氧化应激作用 James, Briana N.; Oyeniran, Clement; Sturgill, Jamie L.; Newton, Jason; Martin, Rebecca K.; Bieberich, Erhard; Weigel, Cynthia; Maczis, Melissa A.; Palladino, Elisa N. D.; Lownik, Joseph C.; Trudeau, John B.; Cook-Mills, Joan M.; Wenzel, Sally; Milstien, Sheldon; Spiegel, Sarah 分享 收藏
Targeting defective sphingosine kinase 1 in Niemann?Pick type C disease with an activator mitigates cholesterol accumulation Newton, Jason; Palladino, Elisa N. D.; Weigel, Cynthia; Maceyka, Michael; Graler, Markus H.; Senkal, Can E.; Enriz, Ricardo D.; Marvanova, Pavlina; Jampilek, Josef; Lima, Santiago; Milstien, Sheldon; Spiegel, Sarah 分享 收藏
分享 收藏
分享 收藏
Sphingosine kinase 1 activation by estrogen receptor α36 contributes to tamoxifen resistance in breast cancer Maczis, Melissa A.; Maceyka, Michael; Waters, Michael R.; Newton, Jason; Singh, Manjulata; Rigsby, Madisyn F.; Turner, Tia H.; Alzubi, Mohammad A.; Harrell, J. Chuck; Milstien, Sheldon; Spiegel, Sarah 分享 收藏
ABCC1-Exported Sphingosine-1-phosphate, Produced by Sphingosine Kinase 1, Shortens Survival of Mice and Patients with Breast Cancer Yamada, Akimitsu; Nagahashi, Masayuki; Aoyagi, Tomoyoshi; Huang, Wei-Ching; Lima, Santiago; Hait, Nitai C.; Maiti, Aparna; Kida, Kumiko; Terracina, Krista P.; Miyazaki, Hiroshi; Ishikawa, Takashi; Endo, Itaru; Waters, Michael R.; Qi, Qianya; Yan, Li; Milstien, Sheldon; Spiegel, Sarah; Takabe, Kazuaki 分享 收藏
Targeting the SphK1/S1P/S1PR1 Axis That Links Obesity, Chronic Inflammation, and Breast Cancer Metastasis 靶向连接肥胖、慢性炎症和乳腺癌转移的SphK1/S1P/S1PR1轴 Nagahashi, Masayuki; Yamada, Akimitsu; Katsuta, Eriko; Aoyagi, Tomoyoshi; Huang, Wei-Ching; Terracina, Krista P.; Hait, Nitai C.; Allegood, Jeremy C.; Tsuchida, Junko; Yuza, Kizuki; Nakajima, Masato; Abe, Manabu; Sakimura, Kenji; Milstien, Sheldon; Wakai, Toshifumi; Spiegel, Sarah; Takabe, Kazuaki 分享 收藏
TP53 is required for BECN1-and ATG5-dependent cell death induced by sphingosine kinase 1 inhibition Lima, Santiago; Takabe, Kazuaki; Newton, Jason; Saurabh, Kumar; Young, Megan M.; Leopoldino, Andreia Machado; Hait, Nitai C.; Roberts, Jane L.; Wang, Hong-Gang; Dent, Paul; Milstien, Sheldon; Booth, Laurence; Spiegel, Sarah 分享 收藏
分享 收藏
FTY720/fingolimod increases NPC1 and NPC2 expression and reduces cholesterol and sphingolipid accumulation in Niemann-Pick type C mutant fibroblasts Newton, Jason; Hait, Nitai C.; Maceyka, Michael; Colaco, Alexandria; Maczis, Melissa; Wassif, Christopher A.; Cougnoux, Antony; Porter, Forbes D.; Milstien, Sheldon; Platt, Nicholas; Platt, Frances M.; Spiegel, Sarah 分享 收藏
分享 收藏
Interstitial Fluid Sphingosine-1-Phosphate in Murine Mammary Gland and Cancer and Human Breast Tissue and Cancer Determined by Novel Methods Nagahashi, Masayuki; Yamada, Akimitsu; Miyazaki, Hiroshi; Allegood, Jeremy C.; Tsuchida, Junko; Aoyagi, Tomoyoshi; Huang, Wei-Ching; Terracina, Krista P.; Adams, Barbara J.; Rashid, Omar M.; Milstien, Sheldon; Wakai, Toshifumi; Spiegel, Sarah; Takabe, Kazuaki 分享 收藏
Sphingosine-1-phosphate phosphatase 2 promotes disruption of mucosal integrity, and contributes to ulcerative colitis in mice and humans Huang, Wei-Ching; Liang, Jie; Nagahashi, Masayuki; Avni, Dorit; Yamada, Akimitsu; Maceyka, Michael; Wolen, Aaron R.; Kordula, Tomasz; Milstien, Sheldon; Takabe, Kazuaki; Oravecz, Tamas; Spiegel, Sarah 分享 收藏
Aberrant ORM (yeast)-like protein isoform 3 (ORMDL3) expression dysregulates ceramide homeostasis in cells and ceramide exacerbates allergic asthma in mice Oyeniran, Clement; Sturgill, Jamie L.; Hait, Nitai C.; Huang, Wei-Ching; Avni, Dorit; Maceyka, Michael; Newton, Jason; Allegood, Jeremy C.; Montpetit, Alison; Conrad, Daniel H.; Milstien, Sheldon; Spiegel, Sarah 分享 收藏
Spinster 2, a sphingosine-1-phosphate transporter, plays a critical role in inflammatory and autoimmune diseases Donoviel, Michael S.; Hait, Nitai C.; Ramachandran, Subramaniam; Maceyka, Michael; Takabe, Kazuaki; Milstien, Sheldon; Oravecz, Tamas; Spiegel, Sarah 分享 收藏
.png){kind=icon}
未登录.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
