未登录Functional precision oncology platform of BRAFV600E-mutated colorectal cancer organoids predicts therapy response and reveals RNF43-mediated immunogenicityBRAFV600E突变结直肠癌类器官的功能精准肿瘤学平台预测治疗反应并揭示RNF43介导的免疫原性
Mo, Shaobo; Luo, Wenqin; Yang, Jiajun; He, Xingfeng; Ma, Maoguang; Cai, Xin; Li, Yaqi; Hu, Xiang; Mu, Peiyuan; Cai, Sanjun; Ma, Xiaoji; Liu, Fangqi; He, Xigan; Zou, Hai; Peng, Junjie .png)
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收藏Microbiome dysbiosis, neutrophil recruitment and mesenchymal transition of mesothelial cells promotes peritoneal metastasis of colorectal cancer微生物组失调、中性粒细胞招募和间皮细胞的间充质转化促进结直肠癌的腹膜转移Li, Qingguo; Xiao, Yiwei; Han, Lingyu; Luo, Wenqin; Dai, Weixing; Fang, Hongsheng; Wang, Renjie; Xu, Ye; Cai, Sanjun; Goel, Ajay; Cai, Guoxiang 分享 收藏 分享 收藏 Effective identification of primary liver cancer from cirrhosis or chronic hepatitis virus infection using eight methylated plasma DNA markers: Marker discovery, phase I pilot, and phase II clinical validationYang, T.; Wang, N.; Zhu, X.; Wang, M.; Yao, L.; Fan, Z.; Sun, X.; Pan, M.; Zhang, L.; You, Q.; Xu, J.; Xu, Y.; Lu, H.; Li, B.; Wang, G.; Cai, S.; Shen, F.; Lv, G. 分享 收藏 Newly developed 3D in vitro models to study tumor-immune interaction新开发的3D体外模型研究肿瘤-免疫相互作用Mu, Peiyuan; Zhou, Shujuan; Lv, Tao; Xia, Fan; Shen, Lijun; Wan, Juefeng; Wang, Yaqi; Zhang, Hui; Cai, Sanjun; Peng, Junjie; Hua, Guoqiang; Zhang, Zhen 分享 收藏 Neoadjuvant chemoradiotherapy combined with immunotherapy for locally advanced rectal cancer: A new era for anal preservationWang, Yaqi; Shen, Lijun; Wan, Juefeng; Zhang, Hui; Wu, Ruiyan; Wang, Jingwen; Wang, Yan; Xu, Ye; Cai, Sanjun; Zhang, Zhen; Xia, Fan 分享 收藏 Utility of Circulating Free DNA Fragmentomics in the Prediction of Pathological Response after Neoadjuvant Chemoradiotherapy in Locally Advanced Rectal CancerWang, Yaqi; Fan, Xiaojun; Bao, Hua; Xia, Fan; Wan, Juefeng; Shen, Lijun; Wang, Yan; Zhang, Hui; Wei, Yulin; Wu, Xue; Shao, Yang; Li, Xinxiang; Xu, Ye; Cai, Sanjun; Zhang, Zhen 分享 收藏 Patient-Derived Organoids from Colorectal Cancer with Paired Liver Metastasis Reveal Tumor Heterogeneity and Predict Response to Chemotherapy来自结直肠癌并配对肝转移的患者来源的类器官揭示了肿瘤异质性并预测了对化疗的反应Mo, Shaobo; Tang, Peiyuan; Luo, Wenqin; Zhang, Long; Li, Yaqi; Hu, Xiang; Ma, Xiaoji; Chen, Yikuan; Bao, Yichao; He, Xingfeng; Fu, Guoxiang; Xu, Xiaoya; Rao, Xinxin; Li, Xiaomeng; Guan, Ruoyu; Chen, Shengzhi; Deng, Yun; Lv, Tao; Mu, Peiyuan; Zheng, Qiang; Wang, Simin; Liu, Fangqi; Li, Yiwei; Sheng, Weiqi; Huang, Dan; Hu, Chen; Gao, Jianjun; Zhang, Zhen; Cai, Sanjun; Clevers, Hans; Peng, Junjie; Hua, Guoqiang 分享 收藏 Postoperative circulating tumor DNA combined with consensus molecular subtypes can better predict outcomes in stage III colon cancers: A prospective cohort study术后循环肿瘤DNA联合共有分子亚型可更好地预测III期结肠癌的预后: 一项前瞻性队列研究Li, Yaqi; Mo, Shaobo; Zhang, Long; Ma, Xiaoji; Hu, Xiang; Huang, Dan; Lu, Binbin; Luo, Chonglin; Peng, Haixiang; Cai, Sanjun; Sheng, Weiqi; Peng, Junjie 分享 收藏 An ultra-sensitive assay using cell-free DNA fragmentomics for multi-cancer early detection使用无细胞DNA片段组学进行多癌症早期检测的超敏感分析Bao, Hua; Wang, Zheng; Ma, Xiaoji; Guo, Wei; Zhang, Xiangyu; Tang, Wanxiangfu; Chen, Xin; Wang, Xinyu; Chen, Yikuan; Mo, Shaobo; Liang, Naixin; Ma, Qianli; Wu, Shuyu; Xu, Xiuxiu; Chang, Shuang; Wei, Yulin; Zhang, Xian; Bao, Hairong; Liu, Rui; Yang, Shanshan; Jiang, Ya; Wu, Xue; Li, Yaqi; Zhang, Long; Tan, Fengwei; Xue, Qi; Liu, Fangqi; Cai, Sanjun; Gao, Shugeng; Peng, Junjie; Zhou, Jian; Shao, Yang 分享 收藏 Short-course radiotherapy combined with CAPOX and Toripalimab for the total neoadjuvant therapy of locally advanced rectal cancer: a randomized, prospective, multicentre, double-arm, phase II trial (TORCH)短程放疗联合CAPOX和Toripalimab用于局部晚期直肠癌的全部新辅助治疗: 一项随机，前瞻性，多中心，双臂，II期试验 (TORCH)Wang, Yaqi; Shen, Lijun; Wan, Juefeng; Zhang, Hui; Wu, Ruiyan; Wang, Jingwen; Wang, Yan; Xu, Ye; Cai, Sanjun; Zhang, Zhen; Xia, Fan 分享 收藏 Highly-metastatic colorectal cancer cell released miR-181a-5p-rich extracellular vesicles promote liver metastasis by activating hepatic stellate cells and remodelling the tumour microenvironmentmiR-181a-5p-rich细胞外囊泡释放的高转移性结直肠癌细胞通过激活肝星状细胞和重塑肿瘤微环境促进肝转移Zhao, Senlin; Mi, Yushuai; Zheng, Binbin; Wei, Ping; Gu, Yanzi; Zhang, Zhengxiang; Xu, Ye; Cai, Sanjun; Li, Xinxiang; Li, Dawei 分享 收藏 Multi-dimensional fragmentomic assay for ultrasensitive early detection of colorectal advanced adenoma and adenocarcinomaMa, Xiaoji; Chen, Yikuan; Tang, Wanxiangfu; Bao, Hua; Mo, Shaobo; Liu, Rui; Wu, Shuyu; Bao, Hairong; Li, Yaqi; Zhang, Long; Wu, Xue; Cai, Sanjun; Shao, Yang; Liu, Fangqi; Peng, Junjie 分享 收藏 分享 收藏 Postoperative circulating tumor DNA as markers of recurrence risk in stages II to III colorectal cancer术后循环肿瘤DNA作为II至III期结直肠癌复发风险的标志物Chen, Gong; Peng, Junjie; Xiao, Qian; Wu, Hao-Xiang; Wu, Xiaojun; Wang, Fulong; Li, Liren; Ding, Peirong; Zhao, Qi; Li, Yaqi; Wang, Da; Shao, Yang; Bao, Hua; Pan, Zhizhong; Ding, Ke-Feng; Cai, Sanjun; Wang, Feng; Xu, Rui-Hua 分享 收藏 分享 收藏 SIRT1 inhibitors mitigate radiation-induced GI syndrome by enhancing intestinal-stem-cell survivalFu, Guoxiang; Chen, Shengzhi; Liang, Liping; Li, Xiaomeng; Tang, Peiyuan; Rao, Xinxin; Pan, Mengxue; Xu, Xiaoya; Li, Yuanchuang; Yao, Ye; Zhou, Yi; Gao, Jun; Mo, Shaobo; Cai, Sanjun; Peng, Junjie; Zhang, Zhen; Clevers, Hans; Gao, Jianjun; Hua, Guoqiang 分享 收藏 Tumor-derived exosomal miR-934 induces macrophage M2 polarization to promote liver metastasis of colorectal cancer (vol 13, 156, 2020)Zhao, Senlin; Mi, Yushuai; Guan, Bingjie; Zheng, Binbin; Wei, Ping; Gu, Yanzi; Zhang, Zhengxiang; Cai, Sanjun; Xu, Ye; Li, Xinxiang; He, Xuefeng; Zhong, Xinyang; Li, Guichao; Chen, Zhiyu; Li, Dawei 分享 收藏 分享 收藏 Establishment and identification of organoids from human circulating colorectal cancer cellsZhang, Long; Mo, Shaobo; Hu, Xiang; Ma, Xiaoji; Jin, Weixiang; Peng, David Haixiang; Zhou, Yu; Liang, Xiaofei; Rao, Xinxin; Xu, Xiaoya; Zhang, Zhen; Hua, Guoqiang; Cai, Sanjun; Li, Yaqi; Peng, Junjie 分享 收藏 
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