Claire L. Harris - Publications, H-index & Citations

Claire L. Harris

newcastle university - uk

52H指数

205论文数

8.8K被引数

收录论文 120

发表时间

The role of complement factor I rare genetic variants in age related macular degeneration in Finland 补体因子I罕见遗传变异在芬兰年龄相关性黄斑变性中的作用

HUMAN MOLECULAR GENETICS

IF3.2

2024-11-25

OAAI

Andreadi, Anneliza; Hallam, Thomas M.; Brocklebank, Vicky; Sharp, Scott J.; Walsh, Patrick R.; Southerington, Tom; Hautalahti, Marco; Steel, David H.; Lotery, Andrew J.; Harris, Claire L.; Marchbank, Kevin J.; Kavanagh, David; Jones, Amy, V

Bruch's Membrane: A Key Consideration with Complement-Based Therapies for Age-Related Macular Degeneration

JOURNAL OF CLINICAL MEDICINE

IF2.9

2023-04-14

OAAI

Hammadi, Sarah; Tzoumas, Nikolaos; Ferrara, Mariantonia; Meschede, Ingrid Porpino; Lo, Katharina; Harris, Claire; Lako, Majlinda; Steel, David H.

A novel method for real-time analysis of the complement C3b:FH:FI complex reveals dominant negative CFI variants in age-related macular degeneration

FRONTIERS IN IMMUNOLOGY

IF5.9

2022-12-28

OAAI

Hallam, Thomas M. M.; Cox, Thomas E. E.; Smith-Jackson, Kate; Brocklebank, Vicky; Baral, April J. J.; Tzoumas, Nikolaos; Steel, David H. H.; Wong, Edwin K. S.; Shuttleworth, Victoria G. G.; Lotery, Andrew J. J.; Harris, Claire L. L.; Marchbank, Kevin J. J.; Kavanagh, David

The complement alternative pathway in health and disease-activation or amplification?

IMMUNOLOGICAL REVIEWS

IF8.3

2022-11-24

OAAI

Harrison, Richard. A. A.; Harris, Claire. L. L.; Thurman, Joshua. M. M.

Gene targeting as a therapeutic avenue in diseases mediated by the complement alternative pathway 基因靶向作为补体替代途径介导的疾病的治疗途径

IMMUNOLOGICAL REVIEWS

IF8.3

2022-11-12

OAAI

Dreismann, Anna K.; Hallam, Thomas M.; Tam, Lawrence C. S.; Nguyen, Calvin, V; Hughes, Jane P.; Ellis, Scott; Harris, Claire L.

Visualization for epidemiological modelling: challenges, solutions, reflections and recommendations (vol A380, 20210299. 2022)

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES

IF3.7

2022-09-12

OAAI

Dykes, Jason; Abdul-Rahman, Alfie; Archambault, Daniel; Bach, Benjamin; Borgo, Rita; Chen, Min; Enright, Jessica; Fang, Hui; Firat, Elif E.; Freeman, Euan; Gonen, Tuna; Harris, Claire; Jianu, Radu; John, Nigel W.; Khan, Saiful; Lahiff, Andrew; Laramee, Robert S.; Matthews, Louise; Mohr, Sibylle; Nguyen, Phong H.; Rahat, Alma A. M.; Reeve, Richard; Ritsos, Panagiotis D.; Roberts, Jonathan C.; Slingsby, Aidan; Swallow, Ben; Torsney-Weir, Thomas; Turkay, Cagatay; Turner, Robert; Vidal, Franck P.; Wang, Qiru; Wood, Jo; Xu, Kai

Evaluating a Causal Relationship between Complement Factor I Protein Level and Advanced Age-Related Macular Degeneration Using Mendelian Randomization

OPHTHALMOLOGY SCIENCE

IF4.6

2022-06-01

OAAI

Jones, Amy, V; MacGregor, Stuart; Han, Xikun; Francis, James; Harris, Claire; Kavanagh, David; Lotery, Andrew; Waheed, Nadia

C3 Glomerulopathy and Related Disorders in Children: Etiology-Phenotype Correlation and Outcomes 儿童C3肾小球病和相关疾病: 病因-表型相关性和结果

CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

IF7.1

2021-11-01

OAAI

Wong, Edwin K. S.; Marchbank, Kevin J.; Lomax-Browne, Hannah; Pappworth, Isabel Y.; Denton, Harriet; Cooke, Katie; Ward, Sophie; Mcloughlin, Amy-Claire; Richardson, Grant; Wilson, Valerie; Harris, Claire L.; Morgan, B. Paul; Hakobyan, Svetlana; McAlinden, Paul; Gale, Daniel P.; Maxwell, Heather; Christian, Martin; Malcomson, Roger; Goodship, Timothy H. J.; Marks, Stephen D.; Pickering, Matthew C.; Kavanagh, David; Cook, H. Terence; Johnson, Sally A.

Novel Selection Approaches to Identify Antibodies Targeting Neoepitopes on the C5b6 Intermediate Complex to Inhibit Membrane Attack Complex Formation 鉴定靶向C5b6中间复合物上的新表位的抗体以抑制膜攻击复合物形成的新型选择方法

ANTIBODIES

IF2.7

2021-10-12

OAAI

Stach, Lasse; Dinley, Emily K. H.; Tournier, Nadia; Bingham, Ryan P.; Gormley, Darren A.; Bramhall, Jo L.; Taylor, Adam; Clarkson, Jane E.; Welbeck, Katherine A.; Harris, Claire L.; Feeney, Maria; Hughes, Jane P.; Sepp, Armin; Batuwangala, Thil D.; Kitchen, Semra J.; Nichols, Eva-Maria

Insights Into the Structure-Function Relationships of Dimeric C3d Fragments

FRONTIERS IN IMMUNOLOGY

IF5.9

2021-08-09

OAAI

Wahid, Ayla A.; Dunphy, Rhys W.; Macpherson, Alex; Gibson, Beth G.; Kulik, Liudmila; Whale, Kevin; Back, Catherine; Hallam, Thomas M.; Alkhawaja, Bayan; Martin, Rebecca L.; Meschede, Ingrid; Laabei, Maisem; Lawson, Alastair D. G.; Holers, V. Michael; Watts, Andrew G.; Crennell, Susan J.; Harris, Claire L.; Marchbank, Kevin J.; van den Elsen, Jean M. H.

The rare C9 P167S risk variant for age-related macular degeneration increases polymerization of the terminal component of the complement cascade

HUMAN MOLECULAR GENETICS

IF3.2

2021-03-30

OAAI

McMahon, O.; Hallam, T. M.; Patel, S.; Harris, C. L.; Menny, A.; Zelek, W. M.; Widjajahakim, R.; Java, A.; Cox, T. E.; Tzoumas, N.; Steel, D. H. W.; Shuttleworth, V. G.; Smith-Jackson, K.; Brocklebank, V; Griffiths, H.; Cree, A. J.; Atkinson, J. P.; Lotery, A. J.; Bubeck, D.; Morgan, B. P.; Marchbank, K. J.; Seddon, J. M.; Kavanagh, D.

Incorporation of CD55 into the Zika Viral Envelope Contributes to Its Stability against Human Complement

VIRUSES-BASEL

IF3.5

2021-03-19

OAAI

Malekshahi, Zahra; Bernklau, Sarah; Schiela, Britta; Koske, Iris; Banki, Zoltan; Stiasny, Karin; Harris, Claire L.; Wurzner, Reinhard; Stoiber, Heribert

Revisiting the role of factor H in age-related macular degeneration: Insights from complement-mediated renal disease and rare genetic variants

SURVEY OF OPHTHALMOLOGY

IF5.9

2021-03-01

PREAI

Tzoumas, Nikolaos; Hallam, Dean; Harris, Claire L.; Lako, Majlinda; Kavanagh, David; Steel, David H. W.

Functional Characterization of Rare Genetic Variants in the N-Terminus of Complement Factor H in aHUS, C3G, and AMD

FRONTIERS IN IMMUNOLOGY

IF5.9

2021-01-14

OAAI

Wong, Edwin K. S.; Hallam, Thomas M.; Brocklebank, Vicky; Walsh, Patrick R.; Smith-Jackson, Kate; Shuttleworth, Victoria G.; Cox, Thomas E.; Anderson, Holly E.; Barlow, Paul Nigel; Marchbank, Kevin James; Harris, Claire L.; Kavanagh, David

Sweet turning bitter: Carbohydrate sensing of complement in host defence and disease

BRITISH JOURNAL OF PHARMACOLOGY

IF7.7

2020-12-23

OAAI

Hevey, Rachel; Pouw, Richard B.; Harris, Claire; Ricklin, Daniel

Complement modulation reverses pathology inY402H-retinal pigment epithelium cell model of age-related macular degeneration by restoring lysosomal function

STEM CELLS TRANSLATIONAL MEDICINE

IF4.9

2020-08-20

OAAI

Cerniauskas, Edvinas; Kurzawa-Akanbi, Marzena; Xie, Long; Hallam, Dean; Moya-Molina, Marina; White, Kathryn; Steer, David; Doherty, Mary; Whitfield, Phil; Al-Aama, Jumana; Armstrong, Lyle; Kavanagh, David; Lambris, John D.; Korolchuk, Viktor, I; Harris, Claire; Lako, Majlinda

Rare Genetic Variants in Complement Factor I Lead to Low FI Plasma Levels Resulting in Increased Risk of Age-Related Macular Degeneration 补体因子I的罕见遗传变异导致低FI血浆水平，导致年龄相关性黄斑变性的风险增加

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

IF4.7

2020-06-09

OAAI

Hallam, Thomas M.; Marchbank, Kevin J.; Harris, Claire L.; Osmond, Clive; Shuttleworth, Victoria G.; Griffiths, Helen; Cree, Angela J.; Kavanagh, David; Lotery, Andrew J.

Long-term outcomes and response to treatment in diacylglycerol kinase epsilon nephropathy 二酰甘油激酶 ε 肾病的长期结果和治疗反应

KIDNEY INTERNATIONAL

IF12.6

2020-06-01

OAAI

Brocklebank, Vicky; Kumar, Gurinder; Howie, Alexander J.; Chandar, Jayanthi; Milford, David, V; Craze, Janet; Evans, Jonathan; Finlay, Eric; Freundlich, Michael; Gale, Daniel P.; Inward, Carol; Mraz, Martin; Jones, Caroline; Wong, William; Marks, Stephen D.; Connolly, John; Corner, Bronte M.; Smith-Jackson, Kate; Walsh, Patrick R.; Marchbank, Kevin J.; Harris, Claire L.; Wilson, Valerie; Wong, Edwin K. S.; Malina, Michal; Johnson, Sally; Sheerin, Neil S.; Kavanagh, David

Severe type I interferonopathy and unrestrained interferon signaling due to a homozygous germline mutation in STAT2

SCIENCE IMMUNOLOGY

IF16.3

2019-12-06

OAAI

Duncan, Christopher J. A.; Thompson, Benjamin J.; Chen, Rui; Rice, Gillian, I; Gothe, Florian; Young, Dan F.; Lovell, Simon C.; Shuttleworth, Victoria G.; Brocklebank, Vicky; Corner, Bronte; Skelton, Andrew J.; Bondet, Vincent; Coxhead, Jonathan; Duffy, Darragh; Fourrage, Cecile; Livingston, John H.; Pavaine, Julija; Cheesman, Edmund; Bitetti, Stephania; Grainger, Angela; Acres, Meghan; Innes, Barbara A.; Mikulasova, Aneta; Sun, Ruyue; Hussain, Rafiqul; Wright, Ronnie; Wynn, Robert; Zarhrate, Mohammed; Zeef, Leo A. H.; Wood, Katrina; Hughes, Stephen M.; Harris, Claire L.; Engelhardt, Karin R.; Crow, Yanick J.; Randall, Richard E.; Kavanagh, David; Hambleton, Sophie; Briggs, Tracy A.

Compendium of current complement therapeutics 当前补体治疗学纲要

MOLECULAR IMMUNOLOGY

IF3

2019-10-01

117

OAAI

Zelek, Wioleta M.; Xie, Long; Morgan, B. Paul; Harris, Claire L.

研究方向