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Laser-activated nanoparticles rewire tumor microenvironment enhancing PD-1 blockade and T cell response in cholangiocarcinoma 激光激活的纳米颗粒重塑肿瘤微环境,增强PD-1阻断和T细胞反应在胆管癌中的作用 Minini, Mirko; Avveduto, Giulio; Becharef, Sonia; Meunier-Thaens, Marie; Lekbaby, Bouchra; Perez-Lazon, Maria; Machado, Alice; Guilbert, Thomas; Lesieur, Julie; Renault, Gilles; Ceccacci, Sara; Guerrera, Ida Chiara; Klein, Christophe; Augustin, Jeremy; Bazzi, Rana; Roux, Stephane; Pol, Jonathan; Donnadieu, Emmanuel; Gazeau, Florence; Fouassier, Laura 分享 收藏
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Deep learning-based phenotyping reclassifies combined hepatocellular-cholangiocarcinoma Calderaro, Julien; Ghaffari Laleh, Narmin; Zeng, Qinghe; Maille, Pascale; Favre, Loetitia; Pujals, Anais; Klein, Christophe; Bazille, Celine; Heij, Lara R.; Uguen, Arnaud; Luedde, Tom; Di Tommaso, Luca; Beaufrere, Aurelie; Chatain, Augustin; Gastineau, Delphine; Nguyen, Cong Trung; Nguyen-Canh, Hiep; Thi, Khuyen Nguyen; Gnemmi, Viviane; Graham, Rondell P.; Charlotte, Frederic; Wendum, Dominique; Vij, Mukul; Allende, Daniela S.; Aucejo, Federico; Diaz, Alba; Riviere, Benjamin; Herrero, Astrid; Evert, Katja; Calvisi, Diego Francesco; Augustin, Jeremy; Leow, Wei Qiang; Leung, Howard Ho Wai; Boleslawski, Emmanuel; Rela, Mohamed; Francois, Arnaud; Cha, Anthony Wing-Hung; Forner, Alejandro; Reig, Maria; Allaire, Manon; Scatton, Olivier; Chatelain, Denis; Boulagnon-Rombi, Camille; Sturm, Nathalie; Menahem, Benjamin; Frouin, Eric; Tougeron, David; Tournigand, Christophe; Kempf, Emmanuelle; Kim, Haeryoung; Ningarhari, Massih; Michalak-Provost, Sophie; Gopal, Purva; Brustia, Raffaele; Vibert, Eric; Schulze, Kornelius; Ruether, Darius F.; Weidemann, Soeren A.; Rhaiem, Rami; Pawlotsky, Jean-Michel; Zhang, Xuchen; Luciani, Alain; Mule, Sebastien; Laurent, Alexis; Amaddeo, Giuliana; Regnault, Helene; De Martin, Eleonora; Sempoux, Christine; Navale, Pooja; Westerhoff, Maria; Lo, Regina Cheuk-Lam; Bednarsch, Jan; Gouw, Annette; Guettier, Catherine; Lequoy, Marie; Harada, Kenichi; Sripongpun, Pimsiri; Wetwittayaklang, Poowadon; Lomenie, Nicolas; Tantipisit, Jarukit; Kaewdech, Apichat; Shen, Jeanne; Paradis, Valerie; Caruso, Stefano; Kather, Jakob Nikolas 分享 收藏
New hormone receptor-positive breast cancer mouse cell line mimicking the immune microenvironment of anti-PD-1 resistant mammary carcinoma Perez-Lanzon, Maria; Carbonnier, Vincent; Cordier, Pierre; De Palma, Fatima Domenica Elisa; Petrazzuolo, Adriana; Klein, Christophe; Arbaretaz, Floriane; Mangane, Khady; Stoll, Gautier; Martins, Isabelle; Ting, Helene Fohrer; Paillet, Juliette; Mouillet-Richard, Sophie; Le Corre, Delphine; Xiao, Wenjjin; Sroussi, Marine; Desdouets, Chantal; Laurent-Puig, Pierre; Pol, Jonathan; Lopez-Otin, Carlos; Maiuri, Maria Chiara; Kroemer, Guido 分享 收藏
Periostin- and podoplanin-positive cancer-associated fibroblast subtypes cooperate to shape the inflamed tumor microenvironment in aggressive pancreatic adenocarcinoma Neuzillet, Cindy; Nicolle, Remy; Raffenne, Jerome; Tijeras-Raballand, Annemilai; Brunel, Alexia; Astorgues-Xerri, Lucile; Vacher, Sophie; Arbateraz, Floriane; Fanjul, Marjorie; Hilmi, Marc; Samain, Remi; Klein, Christophe; Perraud, Aurelie; Rebours, Vinciane; Mathonnet, Muriel; Bieche, Ivan; Kocher, Hemant; Cros, Jerome; Bousquet, Corinne 分享 收藏
Artificial intelligence predicts immune and inflammatory gene signatures directly from hepatocellular carcinoma histology 人工智能直接从肝细胞癌组织学中预测免疫和炎症基因特征 Zeng, Qinghe; Klein, Christophe; Caruso, Stefano; Maille, Pascale; Laleh, Narmin Ghaffari; Sommacale, Daniele; Laurent, Alexis; Amaddeo, Giuliana; Gentien, David; Rapinat, Audrey; Regnault, Helene; Charpy, Cecile; Cong Trung Nguyen; Tournigand, Christophe; Brustia, Raffaele; Pawlotsky, Jean Michel; Kather, Jakob Nikolas; Maiuri, Maria Chiara; Lomenie, Nicolas; Calderaro, Julien 分享 收藏
Transcriptional Regulation of Jaw Osteoblasts: Development to Pathology Nassif, A.; Lignon, G.; Asselin, A.; Zadikian, C. C.; Petit, S.; Sun, H. W.; Klein, C.; Ferre, F. C.; Morasso, M. I.; Berdal, A.; Fournier, B. P. J.; Isaac, J. 分享 收藏
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Acidosis-induced activation of distal nephron principal cells triggers Gdf15 secretion and adaptive proliferation of intercalated cells Cheval, Lydie; Viollet, Benoit; Klein, Christophe; Rafael, Chloe; Figueres, Lucile; Devevre, Estelle; Zadigue, Georges; Azroyan, Anie; Crambert, Gilles; Vogt, Bruno; Doucet, Alain 分享 收藏
Ileal immune tonus is a prognosis marker of proximal colon cancer in mice and patients 回肠免疫张力是小鼠和患者近端结肠癌的预后标志物 Picard, Marion; Yonekura, Satoru; Slowicka, Karolina; Petta, Ioanna; Rauber, Conrad; Routy, Bertrand; Richard, Corentin; Iebba, Valerio; Alou, Maryam Tidjani; Becharef, Sonia; Ly, Pierre; Pizzato, Eugenie; Lehmann, Christian H. K.; Amon, Lukas; Klein, Christophe; Opolon, Paule; Boneca, Ivo Gomperts; Scoazec, Jean-Yves; Hollebecque, Antoine; Malka, David; Ghiringhelli, Francois; Dudziak, Diana; Berx, Geert; Vereecke, Lars; van Loo, Geert; Kroemer, Guido; Zitvogel, Laurence; Roberti, Maria Paula 分享 收藏
Chemotherapy-induced ileal crypt apoptosis and the ileal microbiome shape immunosurveillance and prognosis of proximal colon cancer 化疗诱导的回肠隐窝凋亡与回肠菌群形态免疫监视及近端结肠癌预后的关系 Roberti, Maria Paula; Yonekura, Satoru; Duong, Connie P. M.; Picard, Marion; Ferrere, Gladys; Alou, Maryam Tidjani; Rauber, Conrad; Iebba, Valerio; Lehmann, Christian H. K.; Amon, Lukas; Dudziak, Diana; Derosa, Lisa; Routy, Bertrand; Flament, Caroline; Richard, Corentin; Daillere, Romain; Fluckiger, Aurelie; Van Seuningen, Isabelle; Chamaillard, Mathias; Vincent, Audrey; Kourula, Stephanie; Opolon, Paule; Ly, Pierre; Pizzato, Eugenie; Becharef, Sonia; Paillet, Juliette; Klein, Christophe; Marliot, Florence; Pietrantonio, Filippo; Benoist, Stephane; Scoazec, Jean-Yves; Dartigues, Peggy; Hollebecque, Antoine; Malka, David; Pages, Franck; Galon, Jerome; Boneca, Ivo Gomperts; Lepage, Patricia; Ryffel, Bernard; Raoult, Didier; Eggermont, Alexander; Vanden Berghe, Tom; Ghiringhelli, Francois; Vandenabeele, Peter; Kroemer, Guido; Zitvogel, Laurence 分享 收藏
Active Fluctuations of the Nuclear Envelope Shape the Transcriptional Dynamics in Oocytes Almonacid, Maria; Al Jord, Adel; El-Hayek, Stephany; Othmani, Alice; Coulpier, Fanny; Lemoine, Sophie; Miyamoto, Kei; Grosse, Robert; Klein, Christophe; Piolot, Tristan; Mailly, Philippe; Voituriez, Raphael; Genovesio, Auguste; Verlhac, Marie-Helene 分享 收藏
CFH exerts anti-oxidant effects on retinal pigment epithelial cells independently from protecting against membrane attack complex Borras, Celine; Canonica, Jeremie; Jorieux, Sylvie; Abache, Toufik; El Sanharawi, Mohamed; Klein, Christophe; Delaunay, Kimberley; Jonet, Laurent; Salvodelli, Michele; Naud, Marie-Christine; Arsenijevic, Yvan; Shalabi, Andree; Souchaud, Landry; Behar-Cohen, Francine; Dinet, Virginie 分享 收藏
Sustained Type I interferon signaling as a mechanism of resistance to PD-1 blockade Jacquelot, Nicolas; Yamazaki, Takahiro; Roberti, Maria P.; Duong, Connie P. M.; Andrews, Miles C.; Verlingue, Loic; Ferrere, Gladys; Becharef, Sonia; Vetizou, Marie; Daillere, Romain; Messaoudene, Meriem; Enot, David P.; Stoll, Gautier; Ugel, Stefano; Marigo, Ilaria; Ngiow, Shin Foong; Marabelle, Aurlien; Prevost-Blondel, Armelle; Gaudreau, Pierre-Olivier; Gopalakrishnan, Vancheswaran; Eggermont, Alexander M.; Opolon, Paule; Klein, Christophe; Madonna, Gabriele; Ascierto, Paolo A.; Sucker, Antje; Schadendorf, Dirk; Smyth, Mark J.; Soria, Jean-Charles; Kroemer, Guido; Bronte, Vincenzo; Wargo, Jennifer; Zitvogel, Laurence 分享 收藏
Polyploidy spectrum: a new marker of molecular HCC tumour classification Nader, Myriam Bou; Caruso, Stefano; Calderaro, Julien; Donne, Romain; Cadoux, Mathilde; Guilbert, Thomas; Klein, Christophe; Couchy, Gabrielle; Couty, Jean-Pierre; Morizur, Severine; Zucman-Rossi, Jessica; Desdouets, Chantal 分享 收藏
Metabolic enzymes expressed by cancer cells impact the immune infiltrate Stoll, Gautier; Kremer, Margerie; Bloy, Normal; Joseph, Adrien; Castedo, Maria; Meurice, Guillaume; Klein, Christophe; Galluzzi, Lorenzo; Michels, Judith; Kroemer, Guido 分享 收藏
Involvement of neural crest and paraxial mesoderm in oral mucosal development and healing Isaac, Juliane; Nassif, Ali; Asselin, Audrey; Taihi, Ihsene; Fohrer-Ting, Helene; Klein, Christophe; Gogly, Bruno; Berdal, Ariane; Robert, Benoit; Fournier, Benjamin P. 分享 收藏
ROCK-1 mediates diabetes-induced retinal pigment epithelial and endothelial cell blebbing: Contribution to diabetic retinopathy Rothschild, Pierre-Raphael; Salah, Sawsen; Berdugo, Marianne; Gelize, Emmanuelle; Delaunay, Kimberley; Naud, Marie-Christine; Klein, Christophe; Moulin, Alexandre; Savoldelli, Michele; Bergin, Ciara; Jeanny, Jean-Claude; Jonet, Laurent; Arsenijevic, Yvan; Behar-Cohen, Francine; Crisanti, Patricia 分享 收藏