未登录 Discovery of Hepatitis B Virus Surface Antigen Suppressor GS-8873 Kato, Darryl; Choy, Regina Wai-Yan; Canales, Eda; Dick, Ryan A.; Lake, April D.; Shapiro, Nathan D.; Chin, Elbert; Li, Jiayao; Zhang, Jennifer R.; Wu, Qiaoyin; Saito, Roland D.; Metobo, Sammy; Aktoudianakis, Evangelos; Schroeder, Scott D.; Yang, Zheng-Yu; Glatt, Dylan M.; Balsitis, Scott; Gamelin, Lindsay; Yu, Mei; Cheng, Guofeng; Delaney, William E.; Link, John O. 分享 收藏
Characterization of a Novel Capsid Assembly Modulator for the Treatment of Chronic Hepatitis B Virus Infection Burdette, Dara; Hyrina, Anastasia; Song, Zhijuan; Beran, Rudolf K.; Cheung, Tara; Gilmore, Sarah; Kobayashi, Tetsuya; Li, Li; Liu, Yang; Niedziela-Majka, Anita; Medley, Jonathan; Mehra, Upasana; Morganelli, Philip; Novikov, Nikolai; Niu, Congrong; Tam, Danny; Tang, Jennifer; Wang, Jianhong; Yue, Qin; Fletcher, Simon P.; Holdorf, Meghan M.; Delaney, William E.; Feierbach, Becket; Lazerwith, Scott 分享 收藏
Targeting the hepatitis B cccDNA with a sequence-specific ARCUS nuclease to eliminate hepatitis B virus in vivo 用序列特异性ARCUS核酸酶靶向乙型肝炎cccDNA在体内消除乙型肝炎病毒 Gorsuch, Cassandra L.; Nemec, Paige; Yu, Mei; Xu, Simin; Han, Dong; Smith, Jeff; Lape, Janel; van Buuren, Nicholas; Ramirez, Ricardo; Muench, Robert C.; Holdorf, Meghan M.; Feierbach, Becket; Falls, Greg; Holt, Jason; Shoop, Wendy; Sevigny, Emma; Karriker, Forrest; Brown, Robert V.; Joshi, Amod; Goodwin, Tyler; Tam, Ying K.; Lin, Paulo J. C.; Semple, Sean C.; Leatherbury, Neil; Delaney, William E.; Jantz, Derek; Smith, Amy Rhoden 分享 收藏
Targeted Long-Read Sequencing Reveals Comprehensive Architecture, Burden, and Transcriptional Signatures from Hepatitis B Virus-Associated Integrations and Translocations in Hepatocellular Carcinoma Cell Lines Ramirez, Ricardo; van Buuren, Nicholas; Gamelin, Lindsay; Soulette, Cameron; May, Lindsey; Han, Dong; Yu, Mei; Choy, Regina; Cheng, Guofeng; Bhardwaj, Neeru; Chiu, Joy; Muench, Robert C.; Delaney, William E.; Mo, Hongmei; Feierbach, Becket; Li, Li 分享 收藏
Characterization of Hepatitis B Precore/Core-Related Antigens Hong, Xupeng; Luckenbaugh, Laurie; Mendenhall, Megan; Walsh, Renae; Cabuang, Liza; Soppe, Sally; Revill, Peter A.; Burdette, Dara; Feierbach, Becket; Delaney, William; Hu, Jianming 分享 收藏
Toll-Like Receptor 8 Agonist GS-9688 Induces Sustained Efficacy in the Woodchuck Model of Chronic Hepatitis B Daffis, Stephane; Balsitis, Scott; Chamberlain, Jason; Zheng, Jim; Santos, Rex; Rowe, William; Ramakrishnan, Dhivya; Pattabiraman, Divya; Spurlock, Sandra; Chu, Ruth; Kang, Don; Mish, Michael; Ramirez, Ricardo; Li, Li; Li, Bei; Ma, Sarina; Hung, Magdeleine; Voitenleitner, Christian; Yon, Changsuek; Suresh, Manasa; Menne, Stephan; Cote, Paul; Delaney, William E.; Mackman, Richard; Fletcher, Simon P. 分享 收藏
Serum HBsAg clearance has minimal impact on CD8+ T cell responses in mouse models of HBV infection 血清HBsAg清除对HBV感染小鼠模型中CD8 T细胞反应的影响最小 Fumagalli, Valeria; Di Lucia, Pietro; Venzin, Valentina; Bono, Elisa B.; Jordan, Robert; Frey, Christian R.; Delaney, William; Chisari, Francis, V; Guidotti, Luca G.; Iannacone, Matteo 分享 收藏
Discovery of GS-9688 (Selgantolimod) as a Potent and Selective Oral Toll-Like Receptor 8 Agonist for the Treatment of Chronic Hepatitis B Mackman, Richard L.; Mish, Michael; Chin, Gregory; Perry, Jason K.; Appleby, Todd; Aktoudianakis, Vangelis; Metobo, Sammy; Pyun, Peter; Niu, Congrong; Daffis, Stephane; Yu, Helen; Zheng, Jim; Villasenor, Armando G.; Zablocki, Jeff; Chamberlain, Jason; Jin, Haolun; Lee, Gary; Suekawa-Pirrone, Kimberley; Santos, Rex; Delaney, William E.; Fletcher, Simon P. 分享 收藏
Establishment of infectious genotype 4 cell culture-derived hepatitis C virus 感染性基因4型细胞培养丙型肝炎病毒的建立 Watanabe, Noriyuki; Suzuki, Takaya; Date, Tomoko; Hussan, Hussein Aly; Hmwe, Su Su; Aizaki, Hideki; Sugiyama, Masaya; Mizokami, Masashi; Delaney, William; Cheng, Guofeng; Muramatsu, Masamichi; Wakita, Takaji 分享 收藏
Woolly Monkey-HBV Infection in Squirrel Monkeys as a Surrogate Nonhuman Primate Model of HBV Infection Chen, Christopher Y.; Winer, Benjamin Y.; Chavez, Deborah; Guerra, Bernadette; Brasky, Kathleen M.; Eng, Stacey; Salas, Eduardo; Tam, Danny; Simmons, Joe H.; Abee, Christian R.; Delaney, William E.; Ploss, Alexander; Lanford, Robert E.; Voitenleitner, Christian 分享 收藏
Toll-like receptor 7 agonist GS-9620 induces prolonged inhibition of HBV via a type I interferon-dependent mechanism Niu, Congrong; Li, Li; Daffis, Stephane; Lucifora, Julie; Bonnin, Marc; Maadadi, Sarah; Salas, Eduardo; Chu, Ruth; Ramos, Hilario; Livingston, Christine M.; Beran, Rudolf K.; Garg, Abhishek V.; Balsitis, Scott; Durantel, David; Zoulim, Fabien; Delaney, William E.; Fletcher, Simon P. 分享 收藏
Anti-HBV response to toll-like receptor 7 agonist GS-9620 is associated with intrahepatic aggregates of T cells and B cells Li, Li; Barry, Vivian; Daffis, Stephane; Niu, Congrong; Huntzicker, Erik; French, Dorothy M.; Mikaelian, Igor; Lanford, Robert E.; Delaney, William E.; Fletcher, Simon P. 分享 收藏
SOCIAL NETWORKS, ATTACHMENTS AND SUPPORT IN MINOR AFFECTIVE-DISORDERS - A REPLICATION BRUGHA, T; CONROY, R; WALSH, N; DELANEY, W; OHANLON, J; DONDERO, E; DALY, L; HICKEY, N; BOURKE, G 分享 收藏
Capsid Phosphorylation State and Hepadnavirus Virion Secretion Ning, Xiaojun; Basagoudanavar, Suresh H.; Liu, Kuancheng; Luckenbaugh, Laurie; Wei, Duoqian; Wang, Chunyan; Wei, Bo; Zhao, Yingren; Yan, Taotao; Delaney, William; Hu, Jianming 分享 收藏
In vitro and in vivo characterization of the selective toll-like receptor 8 agonist GS-9688 Daffis, S.; Ramakrishnan, D.; Niu, C.; Zheng, J.; Santos, R.; Mish, M.; Chin, G.; Aktoudianakis, V.; Metobo, S.; Pyun, H-J; Yu, H.; Lee, G.; Palazzo, A.; Frey, C.; Pflanz, S.; Delaney, W. E.; Fletcher, S. P.; Mackman, R. 分享 收藏
In vivo pharmacodynamics of GS-5801, a liver targeted prodrug of a lysine demethylase 5 inhibitor with antiviral activity against hepatitis B virus Gilmore, S. A.; Snyder, C. A.; Dick, R.; Matles, M.; Tam, D.; Tay, C. H.; Farand, J.; Paoli, E.; Delaney, W. E.; Feierbach, B.; Notte, G. T. 分享 收藏
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Antiviral activity of GS-5801, a liver-targeted prodrug of a lysine demethylase 5 inhibitor, in a hepatitis B virus primary human hepatocyte infection model Gilmore, S.; Tam, D.; Dick, R.; Appleby, T.; Birkus, G.; Willkom, M.; Delaney, W. E.; Notte, G. T.; Feierbach, B. 分享 收藏
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