Lucía Martínez‐Santamaría

centro de investigación biomédica en red de enfermedades raras

19H指数

55论文数

1.2K被引数

收录论文 25

发表时间

A Mechanistic Map of the Phenotypic Complexity in Recessive Dystrophic Epidermolysis Bullosa Provides Basis for Therapeutic Target Discovery and Drug Repurposing 隐性营养不良性大疱性表皮松解症的表型复杂性机制图谱为治疗靶点发现和药物重定位提供了基础

International Journal of Molecular Sciences

IF4.9

2026-09-22

OAAI

Sara Herráiz-Gil; Miriam Payá-Milans; María del Carmen de Arriba; Lucía Martínez-Santamaría; Carlos Loucera; Nuria Illera; Marcela del Río; Joaquín Dopazo; Carlos León; María José Escámez

MesenSistem-EB: systemic haploidentical mesenchymal stem cell therapy in recessive dystrophic epidermolysis bullosa associated with clinical benefits and correlated with MCP1 and sCD40L dynamics MesenSistem-EB：系统性单倍型间充质干细胞疗法在常染色体隐性营养不良性大疱性表皮松解症中的应用，与临床益处相关，并与MCP1和sCD40L动态变化相关

Frontiers in Immunology

IF5.9

2026-05-05

OAAI

RM Rocío Maseda † ‡; MC María Carmen Arriba † ‡; LM Lucía Martínez-Santamaría ‡; EJ Eva Jiménez ‡; SH Sara Herráiz-Gil ‡; NI Nuria Illera ‡; LQ Lucía Quintana-Castanedo ‡; MG Marta García ‡; SS Susana Suárez-Sancho ‡; RY Rosa Yáñez ‡; IP Isabel Pérez-Conde; MC Marta Carretero ‡; MM Magdalena Martínez-Queipo ‡; RD Raquel de Paz; CL Carlos León ‡; VJ Víctor Jiménez-Yuste ‡; AM Alberto M. Borobia ‡; ÁV Ángeles Vicente ‡; SM Su M. Lwin ‡; JA John A. McGrath ‡; ME María Eugenia Fernández-Santos ‡; NB Nora Butta ‡; RS Rosa Sacedón ‡; MD Marcela del Río ‡; RD Raúl de Lucas ‡; MJ María José Escámez ‡

Unveiling the value of C-reactive protein as a severity biomarker and the IL4/IL13 pathway as a therapeutic target in recessive dystrophic epidermolysis bullosa: A multiparametric cross-sectional study

EXPERIMENTAL DERMATOLOGY

IF3.1

2024-07-29

OAAI

Quintana-Castanedo, Lucia; Sanchez-Ramon, Silvia; Maseda, Rocio; Illera, Nuria; Perez-Conde, Isabel; Molero-Luis, Marta; Butta, Nora; Arias-Salgado, Elena G.; Monzon-Manzano, Elena; Zuluaga, Pilar; Martinez-Santamaria, Lucia; Fernandez-Arquero, Miguel; Llames, Sara G.; Meana, Alvaro; de Lucas, Raul; del Rio, Marcela; Vicente, Angeles; Escamez, Maria Jose; Sacedon, Rosa

Gluten-sensitive enteropathy in recessive dystrophic epidermolysis bullosa

BRITISH JOURNAL OF DERMATOLOGY

IF9.6

2023-09-01

PREAI

Sacedon, Rosa; Carmen de Arriba, M.; Martinez-Santamaria, Lucia; Maseda, Rocio; Herraiz-Gil, Sara; Jimenez, Eva; Rosales, Isabel; Quintana, Lucia; Illera, Nuria; Garcia, Marta; Butta, Nora; Fernandez-Bello, Ihosvany; Lwin, Su M.; Fernandez-Arquero, Miguel; Leon, Carlos; McGrath, John A.; Angeles Vicente, M.; del Rio, Marcela; de Lucas, Raul; Sanchez-Ramon, Silvia; Jose Escamez, Maria

FPR2 DNA Aptamers for Targeted Therapy of Wound Repair

JOURNAL OF INVESTIGATIVE DERMATOLOGY

IF5.7

2022-08-01

OAAI

del Carmen de Arriba, Maria; Fernandez, Geronimo; Chacon-Solano, Esteban; Mataix, Manuel; Martinez-Santamaria, Lucia; Illera, Nuria; Carrion-Marchante, Rebeca; Elena Martin, Maria; Larcher, Fernando; Gonzalez, Victor M.; Del Rio, Marcela; Carretero, Marta

Evaluation of Systemic Gentamicin as Translational Readthrough Therapy for a Patient With Epidermolysis Bullosa Simplex With Muscular Dystrophy Owing to PLEC1 Pathogenic Nonsense Variants

JAMA DERMATOLOGY

IF11

2022-04-01

OAAI

Martinez-Santamaria, Lucia; Maseda, Rocio; del Carmen de Arriba, Maria; Membrilla, Javier A.; Iglesias Siguenza, Alberto; Mascias, Javier; Garcia, Marta; Quintana, Lucia; Esteban-Rodriguez, Isabel; Pelayo Hernandez-Fernandez, Carlos; Illera, Nuria; Duarte, Blanca; Guerrero-Aspizua, Sara; Woodley, David T.; del Rio, Marcela; de Lucas, Raul; Larcher, Fernando; Jose Escamez, Maria

Hallmarks of the human intestinal microbiome on liver maturation and function

JOURNAL OF HEPATOLOGY

IF33

2022-03-01

OAAI

Almeida, Joana I.; Tenreiro, Miguel F.; Martinez-Santamaria, Luci; Guerrero-Aspizua, Sara; Gisbert, Javier P.; Alves, Paula M.; Serra, Margarida; Baptista, Pedro M.

Beneficial Effect of Systemic Allogeneic Adipose Derived Mesenchymal Cells on the Clinical, Inflammatory and Immunologic Status of a Patient With Recessive Dystrophic Epidermolysis Bullosa: A Case Report

FRONTIERS IN MEDICINE

IF3

2020-11-26

OAAI

Maseda, Rocio; Martinez-Santamaria, Lucia; Sacedon, Rosa; Butta, Nora; del Carmen de Arriba, Maria; Garcia-Barcenilla, Sara; Garcia, Marta; Illera, Nuria; Perez-Conde, Isabel; Carretero, Marta; Jimenez, Eva; Melen, Gustavo; Borobia, Alberto M.; Jimenez-Yuste, Victor; Vicente, Angeles; del Rio, Marcela; de Lucas, Raul; Jose Escamez, Maria

Raloxifene andn-Acetylcysteine Ameliorate TGF-Signalling in Fibroblasts from Patients with Recessive Dominant Epidermolysis Bullosa

CELLS

IF5.2

2020-09-16

OAAI

Aguado, Tania; Garcia, Marta; Garcia, Adela; Ferrer-Mayorga, Gemma; Martinez-Santamaria, Lucia; del Rio, Marcela; Botella, Luisa-Maria; Sanchez-Puelles, Jose-Maria

First-in-human treatment of recessive dystrophic epidermolysis bullosa with adipose derived mesenchymal stromal cells. A case report

JOURNAL OF INVESTIGATIVE DERMATOLOGY

IF5.7

2019-09-01

OAAI

Maseda, R.; Martinez-Santamaria, L.; Sacedon, R.; Butta, N.; Garcia-Barcenilla, S.; Melen, G.; Borobia, A. M.; del Rio, M.; de Lucas, R.; Escamez, M.

Phase I/II efficacy and safety study of mesenchymal stromal cells in recessive dystrophic epidermolysis bullosa

JOURNAL OF INVESTIGATIVE DERMATOLOGY

IF5.7

2019-09-01

OAAI

Martinez-Santamaria, L.; Maseda, R.; Garcia, M.; Chacon-Solano, E.; Garcia-Barcenilla, S.; Lwin, S. M.; McGrath, J. A.; del Rio, M.; de Lucas, R.; Escamez, M.

Fibroblast activation and abnormal extracellular matrix remodelling as common hallmarks in three cancer-prone genodermatoses

BRITISH JOURNAL OF DERMATOLOGY

IF9.6

2019-04-15

OAAI

Chacon-Solano, E.; Leon, C.; Diaz, F.; Garcia-Garcia, F.; Garcia, M.; Escamez, M. J.; Guerrero-Aspizua, S.; Conti, C. J.; Mencia, A.; Martinez-Santamaria, L.; Llames, S.; Pevida, M.; Carbonell-Caballero, J.; Puig-Butille, J. A.; Maseda, R.; Puig, S.; de Lucas, R.; Baselga, E.; Larcher, F.; Dopazo, J.; del Rio, M.

Amperometric determination of endoglin in human serum using disposable immunosensors constructed with poly(pyrrolepropionic) acid-modified electrodes

ELECTROCHIMICA ACTA

IF5.6

2018-12-01

OAAI

Martinez-Perinan, E.; Sanchez-Tirado, E.; Gonzalez-Cortes, A.; Barderas, R.; Sanchez-Puelles, J. M.; Martinez-Santamaria, L.; Campuzano, S.; Yanez-Sedeno, P.; Pingarron, J. M.

Long-term skin regeneration in xenografts from iPSC teratoma-derived human keratinocytes

EXPERIMENTAL DERMATOLOGY

IF3.1

2016-06-30

OAAI

Garcia, Marta; Quintana-Bustamante, Oscar; Segovia, Jose C.; Bueren, Juan; Martinez-Santamaria, Lucia; Guerrero-Aspizua, Sara; Jose Escamez, Maria; Del Rio, Marcela; Larcher, Fernando

Increased Susceptibility to Skin Carcinogenesis Associated with a Spontaneous Mouse Mutation in the Palmitoyl Transferase Zdhhc13 Gene

JOURNAL OF INVESTIGATIVE DERMATOLOGY

IF5.7

2015-12-01

OAAI

Perez, Carlos J.; Mecklenburg, Lars; Jaubert, Jean; Martinez-Santamaria, Lucia; Iritani, Brian M.; Espejo, Alexsandra; Napoli, Eleonora; Song, Gyu; del Rio, Marcela; DiGiovanni, John; Giulivi, Cecilia; Bedford, Mark T.; Dent, Sharon Y. R.; Wood, Richard D.; Kusewitt, Donna F.; Guenet, Jean-Louis; Conti, Claudio J.; Benavides, Fernando

Long-Term Survival of Type XVII Collagen Revertant Cells in an Animal Model of Revertant Cell Therapy

JOURNAL OF INVESTIGATIVE DERMATOLOGY

IF5.7

2014-02-01

OAAI

Gostynski, Antoni; Llames, Sara; Garcia, Marta; Escamez, Maria J.; Martinez-Santamaria, Lucia; Nijenhuis, Miranda; Meana, Alvaro; Pas, Hendri H.; Larcher, Fernando; Pasmooij, Anna M. G.; Jonkman, Marcel F.; Del Rio, Marcela

The regenerative potential of fibroblasts in a new diabetes-induced delayed humanised wound healing model 在新的糖尿病诱导的延迟人伤口愈合模型中成纤维细胞的再生潜力

EXPERIMENTAL DERMATOLOGY

IF3.1

2013-03-12

OAAI

Martinez-Santamaria, Lucia; Conti, Claudio J.; Llames, Sara; Garcia, Eva; Retamosa, Luisa; Holguin, Almudena; Illera, Nuria; Duarte, Blanca; Camblor, Lino; Llaneza, Jose M.; Jorcano, Jose L.; Larcher, Fernando; Meana, Alvaro; Escamez, Maria J.; Del Rio, Marcela

Two novel recessive mutations in KRT14 identified in a cohort of 21 Spanish families with epidermolysis bullosa simplex

BRITISH JOURNAL OF DERMATOLOGY

IF9.6

2011-08-28

PREAI

Garcia, M.; Santiago, J. L.; Terron, A.; Hernandez-Martin, A.; Vicente, A.; Fortuny, C.; De Lucas, R.; Lopez, J. C.; Cuadrado-Corrales, N.; Holguin, A.; Illera, N.; Duarte, B.; Sanchez-Jimeno, C.; Llames, S.; Garcia, E.; Ayuso, C.; Martinez-Santamaria, L.; Castiglia, D.; De Luca, N.; Torrelo, A.; Mechan, D.; Baty, D.; Zambruno, G.; Escamez, M. J.; Del Rio, M.

Assessment of optimal virus-mediated growth factor gene delivery for human cutaneous wound healing enhancement

JOURNAL OF INVESTIGATIVE DERMATOLOGY

IF5.7

2008-06-01

OAAI

Escamez, Maria J.; Carretero, Marta; Garcia, Marta; Martinez-Santamaria, Lucia; Mirones, Isabel; Duarte, Blanca; Holguin, Almudena; Garcia, Eva; Garcia, Veronica; Meana, Alvaro; Jorcano, Jose L.; Larcher, Fernando; Del Rio, Marcela

Modeling normal and pathological processes through skin tissue engineering

MOLECULAR CARCINOGENESIS

IF3.2

2007-07-03

PREAI

Garcia, Marta; Jose Escamez, Maria; Carretero, Marta; Mirones, Isabel; Martinez-Santamaria, Lucia; Navarro, Manuel; Jorcano, Jose L.; Meana, Alvaro; Del Rio, Marcela; Larcher, Fernando

研究方向