Alexander Miethke - Publications, H-index & Citations

Alexander Miethke

cincinnati children hospital medical center

30H指数

136论文数

3.1K被引数

收录论文 59

发表时间

Detection of Low Levels of DNAJB1::PRKACA Fusion KinaseRequires the Utilization of Sensitive Assays and CarefulMethodological Planning. Reply to Palaz et al. Independent Multi-Cohort RNA-Seq Analysis Does Not Support Recurrent DNAJB1::PRKACA Fusion in Hepatoblastoma or Biliary Atresia. Comment on “Fleifil et al. DNAJB1-PKAc Kinase Is Expressed in Young Patients with Pediatric Liver Cancers and Enhances Carcinogenic Pathways. Cancers 2025, 17, 83”检测低水平DNAJB1::PRKACA融合激酶需要利用敏感的检测方法和谨慎的方法学规划。回复给Palaz等人。独立的多个队列RNA测序分析不支持在肝母细胞瘤或胆道闭锁中存在复发性DNAJB1::PRKACA融合。评论“Fleifil等人。DNAJB1-PKAc激酶在患有儿科肝癌的年轻患者中表达并增强致癌通路。Cancers 2025, 17, 83”

Cancers

IF4.4

2026-08-28

OAAI

Yasmeen Fleifil; Ruhi Gulati; Katherine Jennings; Alexander Miethke; Alexander Bondoc; Gregory Tiao; Rebekah Karns; Lubov Timchenko; Nikolai Timchenko

Fusion DNAJB1::PRKACA in Non-Fibrolamellar Cancer Cases. Reply to Arif et al. Global Re-Analysis Confirms Absence of the DNAJB1::PRKACA Fusion in Hepatoblastoma. Comment on “Fleifil et al. DNAJB1-PKAc Kinase Is Expressed in Young Patients with Pediatric Liver Cancers and Enhances Carcinogenic Pathways. Cancers 2025, 17, 83”融合DNAJB1::PRKACA在非纤维板层样癌病例中。回复Arif et al. 全局重分析证实DNAJB1::PRKACA融合在肝母细胞瘤中不存在。评论“Fleifil et al. DNAJB1-PKAc激酶在年轻儿科肝癌患者中表达并增强致癌通路。Cancers 2025, 17, 83”。

Cancers

IF4.4

2026-03-12

OAAI

Yasmeen Fleifil; Ruhi Gulati; Katherine Jennings; Alexander Miethke; Alexander Bondoc; Gregory Tiao; Rebekah Karns; Lubov Timchenko; Nikolai Timchenko

Longitudinal, Multicenter Study of Clinical Factors Impacting Health-Related Quality of Life in Paediatric Autoimmune Liver Disease 纵向、多中心研究：影响儿科自身免疫性肝病健康相关生活质量的临床因素

Liver International

IF5.2

2026-03-10

PREAI

Rebecca Farr; Cyd Castro Rojas; Mosab Alquraish; Kevin Hommel; Rashmi Sahay; Alexander Weymann; Katelyn Saarela; Sakil Kulkarni; Mary Ayers; James Squires; Amy Taylor; Heidi J. Kalkwarf; Alexander Miethke

Prospective Multicenter Longitudinal Measurement of Liver Stiffness in School-Age Children With Cholestatic Liver Disease 前瞻性多中心纵向测量学龄儿童胆汁淤积性肝病的肝脏硬度

Gastro Hep Advances

IF0

2025-10-01

OAAI

Shneider, Benjamin L.; Goodrich, Nathan P.; Ye, Wen; Molleston, Jean P.; Leung, Daniel H.; Sokol, Ronald J.; Cavallo, Laurel; Wang, Kasper; Valentino, Pamela L.; Teckman, Jeffery H.; Squires, James E.; Sundaram, Shikha S.; Rosenthal, Philip; Romero, Rene; Miethke, Alexander G.; Loomes, Kathleen M.; Kohli, Rohit; Karpen, Saul J.; Kamath, Binita M.; Jensen, M. Kyle; Bezerra, Jorge A.; Bass, Lee M.; Magee, John C.

Outcomes of Fontan Patients Undergoing Combined Heart-Liver Transplantation in Pediatric Hospitals Across the United States 美国儿科医院接受心脏-肝脏联合移植的Fontan手术患者的结局

thoracic and cardiovascular surgery

IF0

2025-08-14

PREAI

Grant Chappell; Amir Mehdizadeh-Shrifi; Darren Turner; Alexander Bondoc; Suzanne Evans; Alexander G. Miethke; Gregory Tiao; Meghan M. Chlebowski; Alexander R. Opotowsky; David Lehenbauer; Marco Ricci; Awais Ashfaq; David L.S. Morales

A new multisystem ERCC1-hepatorenal syndrome: insights from a clinical cohort, molecular pathogenesis, and management guidelines 一种新的多系统ERCC1-肝肾综合征：来自临床队列、分子发病机制和管理指南的见解

European Journal of Human Genetics

IF4.6

2025-07-19

OAAI

Susan M. White; Annelotte P. Wondergem; Isa Breet; Maren Dittmaier; Katrina Bell; Christopher M. Richmond; Winita Hardikar; Kanika Bhatia; Catherine Quinlan; David Orchard; Areetha D’Souza; Walter J. Chazin; Christopher Smith; Rebecca Sparkes; Simon Lam; Alexandra Carter; Robert J. Hopkin; Leticia Khendek; Bonnie R. Sullivan; Naja Becher; Anne Katrine W. Simonsen; Helene Kvistgaard; Katherine Dempsey; Alexander G. Miethke; Pernille Axél Gregersen; Eliza Phillips; Martijn S. Luijsterburg

Bile acids engage the SIPR-STAT3 signaling axis to modulate regulatory T cell responses in fibrosing cholangiopathies 胆汁酸通过激活SIPR-STAT3信号轴来调节纤维化胆管病的调节性T细胞反应。

Journal of Hepatology

IF33

2025-06-20

PREAI

Ramesh Kudira; Zi F. Yang; Immaculeta Osuji; Michelle S.M.A. Damen; Annika Yang vom Hofe; Manavi Singh; Rebekah Karns; Priya Bariya; Liva Pfuhler; Mary Mullen; Amy Taylor; Hong Ji; Celine S. Lages; Tiffany Shi; Srikar Pasula; Joseph A. Wayman; Anas Bernieh; Wujuan Zhang; Claire A. Chougnet; David A. Hildeman; Gregory M. Tiao; Stacey S. Huppert; Sanjay Subramanian; Nathan Salomonis; Emily R. Miraldi; Alexander G. Miethke

The relationship between serum bile acids and event-free survival following the use of maralixibat for progressive familial intrahepatic cholestasis: data from MARCH/MARCH-ON

DIGESTIVE AND LIVER DISEASE

IF3.8

2025-02-01

PREAI

D'Antiga, L.; Thompson, R. J.; Horslen, S. P.; Mogul, D. B.; Nunes, T.; Garner, W.; Vig, P.; Miethke, A. G.

Quantitative fibrosis identifies biliary tract involvement and is associated with outcomes in pediatric autoimmune liver disease 定量纤维化可确定胆道受累，并与小儿自身免疫性肝病的结局相关

HEPATOLOGY COMMUNICATIONS

IF4.6

2025-01-01

OAAI

Khendek, Leticia; Castro-Rojas, Cyd; Nelson, Constance; Alquraish, Mosab; Karns, Rebekah; Kasten, Jennifer; Teng, Xiao; Miethke, Alexander G.; Taylor, Amy E.

Gucy1α1 specifically marks kidney, heart, lung and liver fibroblasts

SCIENTIFIC REPORTS

IF3.9

2024-11-26

OAAI

Rudman-Melnick, Valeria; Vanhoutte, Davy; Stowers, Kaitlynn; Sargent, Michelle; Adam, Mike; Ma, Qing; Perl, Anne Karina T.; Miethke, Alexander G.; Burg, Ashley; Shi, Tiffany; Hildeman, David A.; Woodle, E. Steve S.; Kofron, J. Matthew; Devarajan, Prasad

Liver disease and transplantation in telomere biology disorders: An international multicenter cohort

HEPATOLOGY COMMUNICATIONS

IF4.6

2024-07-01

OAAI

Wang, YunZu Michele; Kaj-Carbaidwala, Batul; Lane, Adam; Agarwal, Suneet; Beier, Fabian; Bertuch, Alison; Borovsky, Kristin A.; Brennan, Steven K.; Calado, Rodrigo T.; Catto, Luiz Fernando B.; Dufour, Carlo; Ebens, Christen L.; Fioredda, Francesca; Giri, Neelam; Gloude, Nicholas; Goldman, Frederick; Hertel, Paula M.; Himes, Ryan; Keel, Sioban B.; Koura, Divya T.; Kratz, Christian P.; Kulkarni, Sakil; Liou, Iris; Nakano, Taizo A.; Nastasio, Silvia; Niewisch, Marena R.; Penrice, Daniel D.; Sasa, Ghadir S.; Savage, Sharon A.; Simonetto, Douglas A.; Ziegler, David S.; Miethke, Alexander G.; Myers, Kasiani C.

Maralixibat in progressive familial intrahepatic cholestasis (MARCH-PFIC): a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial

LANCET GASTROENTEROLOGY & HEPATOLOGY

IF38.6

2024-07-01

PREAI

Miethke, Alexander G.; Moukarzel, Adib; Porta, Gilda; Esquer, Joshue Covarrubias; Czubkowski, Piotr; Ordonez, Felipe; Mosca, Antonella; Aqul, Amal A.; Squires, Robert H.; Sokal, Etienne; D'Agostino, Daniel; Baumann, Ulrich; D'Antiga, Lorenzo; Kasi, Nagraj; Laborde, Nolwenn; Arikan, Cigdem; Lin, Chuan-Hao; Gilmour, Susan; Mittal, Naveen; Chiou, Fang Kuan; Horslen, Simon P.; Huber, Wolf -Dietrich; Jaecklin, Thomas; Nunes, Tiago; Lascau, Anamaria; Longpre, Lara; Mogul, Douglas B.; Garner, Will; Vig, Pamela; Hupertz, Vera F.; Gonzalez-Peralta, Regino P.; Ekong, Udeme; Hartley, Jane; Laverdure, Noemie; Ovchinsky, Nadia; Thompson, Richardj

Protein biomarkers GDF15 and FGF21 to differentiate mitochondrial hepatopathies from other pediatric liver diseases

HEPATOLOGY COMMUNICATIONS

IF4.6

2024-01-01

PREAI

Van Hove, Johan L. K.; Friederich, Marisa W.; Strode, Dana K.; Van Hove, Roxanne A.; Miller, Kristen R.; Sharma, Rohit; Shah, Hardik; Estrella, Jane; Gabel, Linda; Horslen, Simon; Kohli, Rohit; Lovell, Mark A.; Miethke, Alexander G.; Molleston, Jean P.; Romero, Rene; Squires, James E.; Alonso, Estella M.; Guthery, Stephen L.; Kamath, Binita M.; Loomes, Kathleen M.; Rosenthal, Philip; Mysore, Krupa R.; Cavallo, Laurel A.; Valentino, Pamela L.; Magee, John C.; Sundaram, Shikha S.; Sokol, Ronald J.

Deleterious variants in TNFAIP3 are associated with type II and seronegative pediatric autoimmune hepatitis

JOURNAL OF HEPATOLOGY

IF33

2024-01-01

PREAI

Pandurangi, Sindhu; Malik, Astha; Owens, Joshua; Valencia, C. Alexander; Miethke, Alexander G.

Red cell abnormalities characterized by ektacytometry in children with cholestasis

PEDIATRIC RESEARCH

IF3.1

2023-12-01

PREAI

Kocoshis, Theodore S.; Kalfa, Theodosia A.; Miethke, Alexander G.; Balistreri, William F.; Seu, Katie G.; Slaughter, Crystal G.; Singh, Ruchi; Mullen, Mary; Kocoshis, Samuel A.

Sarcopenia is associated with osteopenia and impaired quality of life in children with genetic intrahepatic cholestatic liver disease

HEPATOLOGY COMMUNICATIONS

IF4.6

2023-11-01

OAAI

Boster, Julia M.; Goodrich, Nathan P.; Spino, Cathie; Loomes, Kathleen M.; Alonso, Estella M.; Kamath, Binita M.; Sokol, Ronald J.; Karpen, Saul; Miethke, Alexander; Shneider, Benjamin L.; Molleston, Jean P.; Kohli, Rohit; Horslen, Simon P.; Rosenthal, Philip; Valentino, Pamela L.; Teckman, Jeffrey H.; Hangartner, Thomas N.; Sundaram, Shikha S.

Recent Increase in Incidence of Severe Acute Hepatitis of Unknown Etiology in Children is Associated with Infection with Adenovirus and Other Nonhepatotropic Viruses

JOURNAL OF PEDIATRICS

IF3.5

2023-08-01

OAAI

Peters, Anna L.; Kim, Seung; Mourya, Reena; Asai, Akihiro; Taylor, Amy; Rogers, Michael; Campbell, Kathleen; Fei, Lin; Miethke, Alexander; Balistreri, William F.; Bezerra, Jorge A.

Clinical spectrum and genetic causes of mitochondrial hepatopathy phenotype in children

HEPATOLOGY COMMUNICATIONS

IF4.6

2023-06-01

OAAI

Squires, James E.; Miethke, Alexander G.; Valencia, C. Alexander; Hawthorne, Kieran; Henn, Lisa; Van Hove, Johan L. K. H.; Squires, Robert; Bove, Kevin; Horslen, Simon; Kohli, Rohit; Molleston, Jean P.; Romero, Rene; Alonso, Estella M.; Bezerra, Jorge A.; Guthery, Stephen L.; Hsu, Evelyn; Karpen, Saul J.; Loomes, Kathleen M.; Ng, Vicky L.; Rosenthal, Philip; Mysore, Krupa; Wang, Kasper S.; Friederich, Marisa W.; Magee, John C.; Sokol, Ronald J.

Farnesoid X receptor antagonizes macrophage-dependent licensing of effector T lymphocytes and progression of sclerosing cholangitis

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2022-12-14

OAAI

Shi, Tiffany; Malik, Astha; vom Hofe, Annika Yang; Matuschek, Louis; Mullen, Mary; Lages, Celine S.; Kudira, Ramesh; Singh, Ruchi; Zhang, Wujuan; Setchell, Kenneth D. R.; Hildeman, David; Pasare, Chandrashekhar; Wagner, Brandee; Miethke, Alexander G.

Impact of long-term administration of maralixibat on children with cholestasis secondary to Alagille syndrome

HEPATOLOGY COMMUNICATIONS

IF4.6

2022-06-07

OAAI

Shneider, Benjamin L.; Spino, Catherine A.; Kamath, Binita M.; Magee, John C.; Ignacio, Rosalinda, V; Huang, Suiyuan; Horslen, Simon P.; Molleston, Jean P.; Miethke, Alexander G.; Kohli, Rohit; Leung, Daniel H.; Jensen, M. Kyle; Loomes, Kathleen M.; Karpen, Saul J.; Mack, Cara; Rosenthal, Philip; Squires, Robert H.; Baker, Alastair; Rajwal, Sanjay; Kelly, Deirdre; Sokol, Ronald J.; Thompson, Richard J.

研究方向