George Simos - Publications, H-index & Citations

George Simos

university of thessaly

47H指数

118论文数

6.3K被引数

收录论文 61

发表时间

Oxygen-independent expression of HIF-1α during the cell cycle in hepatocellular carcinoma cells controls essential metabolic pathways under normoxia HIF-1α 在肝癌细胞周期中的氧非依赖性表达在常氧条件下控制重要代谢途径

FEBS JOURNAL

IF4.2

2025-11-01

OAAI

Gkotinakou, Ioanna-maria; Arseni, Christina; Koukoulas, Kreon; Samiotaki, Martina; Panayotou, George; Simos, George; Mylonis, Ilias

Interaction of TFAP2A with the Ku70/80 complex is crucial for HIF-dependent activation of hypoxia-inducible genes

FEBS JOURNAL

IF4.2

2025-02-24

OAAI

Kanoura, Amalia; Giakountis, Antonis; Filippopoulou, Chrysa; Karagiota, Angeliki; Stamatakis, George; Samiotaki, Martina; Panayotou, George; Simos, George; Chachami, Georgia

Combinatorial regulation by ERK1/2 and CK1δ protein kinases leads to HIF-1α association with microtubules and facilitates its symmetrical distribution during mitosis

CELLULAR AND MOLECULAR LIFE SCIENCES

IF6.2

2024-02-01

OAAI

Arseni, Christina; Samiotaki, Martina; Panayotou, George; Simos, George; Mylonis, Ilias

Hypoxia-driven deSUMOylation of EXOSC10 promotes adaptive changes in the transcriptome profile

CELLULAR AND MOLECULAR LIFE SCIENCES

IF6.2

2024-01-27

OAAI

Filippopoulou, Chrysa; Thome, Chairini C.; Perdikari, Sofia; Ntini, Evgenia; Simos, George; Bohnsack, Katherine E.; Chachami, Georgia

Yeast Los1p has properties of an exportin-like nucleocytoplasmic transport factor for tRNA

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-28

235

OAAI

Hellmuth, K; Lau, DM; Bischoff, FR; Künzler, M; Hurt, E; Simos, G

Nuclear mRNA export requires complex formation between Mex67p and Mtr2p at the nuclear pores

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-28

254

OAAI

Santos-Rosa, H; Moreno, H; Simos, G; Segref, A; Fahrenkrog, B; Panté, N; Hurt, E

Direct interaction between mortalin and HIF-1α at the mitochondria inhibits apoptosis by blocking recruitment of Bax

FEBS JOURNAL

IF4.2

2023-03-23

OAAI

Yfantis, Angelos; Mylonis, Ilias; Simos, George

Transcriptional Response to Hypoxia: The Role of HIF-1-Associated Co-Regulators 对缺氧的转录反应: HIF-1-Associated共调节因子的作用

CELLS

IF5.2

2023-03-03

OAAI

Yfantis, Angelos; Mylonis, Ilias; Chachami, Georgia; Nikolaidis, Marios; Amoutzias, Grigorios D.; Paraskeva, Efrosyni; Simos, George

Pyruvate dehydrogenase phosphatase 1 (PDP1) stimulates HIF activity by supporting histone acetylation under hypoxia

FEBS JOURNAL

IF4.2

2022-12-19

OAAI

Karagiota, Angeliki; Kanoura, Amalia; Paraskeva, Efrosyni; Simos, George; Chachami, Georgia

Short-term hypoxia triggers ROS and SAFB mediated nuclear matrix and mRNA splicing remodeling

REDOX BIOLOGY

IF11.9

2022-12-01

OAAI

Taze, Chrysa; Drakouli, Sotiria; Samiotaki, Martina; Panayotou, George; Simos, George; Georgatsou, Eleni; Mylonis, Ilias

Hepcidin as a Sensitive and Treatment-Responsive Acute-Phase Marker in Patients with Bacteremia: A Pilot Study 铁调素作为菌血症患者的敏感和治疗反应性急性期标志物: 一项初步研究

DIAGNOSTICS

IF3.3

2022-06-06

OAAI

Koukoulas, Kreon; Lygoura, Vasiliki; Kartalidis, Philip; Gatselis, Nikolaos K.; Petinaki, Efthymia; Dalekos, George N.; Simos, George

ERK signaling controls productive HIF-1 binding to chromatin and cancer cell adaptation to hypoxia through HIF-1α interaction with NPM1

MOLECULAR ONCOLOGY

IF4.5

2021-09-09

OAAI

Koukoulas, Kreon; Giakountis, Antonis; Karagiota, Angeliki; Samiotaki, Martina; Panayotou, George; Simos, George; Mylonis, Ilias

The Role of Sumoylation in the Response to Hypoxia: An Overview Sumo化在缺氧反应中的作用: 概述

CELLS

IF5.2

2020-10-26

OAAI

Filippopoulou, Chrysa; Simos, George; Chachami, Georgia

Hypoxia-induced Changes in SUMO Conjugation Affect Transcriptional Regulation Under Low Oxygen

MOLECULAR & CELLULAR PROTEOMICS

IF5.5

2019-06-01

OAAI

Chachami, Georgia; Stankovic-Valentin, Nicolas; Karagiota, Angeliki; Basagianni, Angeliki; Plessmann, Uwe; Urlaub, Henning; Melchior, Frauke; Simos, George

ERK1/2 phosphorylates HIF-2α and regulates its activity by controlling its CRM1-dependent nuclear shuttling

JOURNAL OF CELL SCIENCE

IF3.6

2019-04-08

OAAI

Gkotinakou, Ioanna-Maria; Befani, Christina; Simos, George; Liakos, Panagiotis

Hypoxia-Inducible Factors and the Regulation of Lipid Metabolism 缺氧诱导因子与脂质代谢的调节

CELLS

IF5.2

2019-03-03

212

OAAI

Mylonis, Ilias; Simos, George; Paraskeva, Efrosyni

Protein phosphatase PPP3CA (calcineurin A) down-regulates hypoxia-inducible factor transcriptional activity

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

IF3

2019-03-01

PREAI

Karagiota, Angeliki; Mylonis, Ilias; Simos, George; Chachami, Georgia

HIF-1-derived cell-penetrating peptides inhibit ERK-dependent activation of HIF-1 and trigger apoptosis of cancer cells under hypoxia

CELLULAR AND MOLECULAR LIFE SCIENCES

IF6.2

2018-12-10

OAAI

Karagiota, Angeliki; Kourti, Maria; Simos, George; Mylonis, Ilias

Expression of AGPAT2, an enzyme involved in the glycerophospholipid/triacylglycerol biosynthesis pathway, is directly regulated by HIF-1 and promotes survival and etoposide resistance of cancer cells under hypoxia

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

IF3.3

2018-09-01

PREAI

Triantafyllou, Eleni-Anastasia; Georgatsou, Eleni; Mylonis, Ilias; Simos, George; Paraskeva, Efrosyni

Downregulation of PERK activity and eIF2α serine 51 phosphorylation by mTOR complex 1 elicits pro-oxidant and pro-death effects in tuberous sclerosis-deficient cells

CELL DEATH & DISEASE

IF9.6

2018-02-15

OAAI

Krishnamoorthy, Jothilatha; Tenkerian, Clara; Gupta, Jyotsana; Ghaddar, Nour; Wang, Shuo; Darini, Cedric; Staschke, Kirk A.; Ghosh, Abhishek; Gandin, Valentina; Topisirovic, Ivan; Kristof, Arnold S.; Hatzoglou, Maria; Simos, George; Koromilas, Antonis E.

研究方向