Naohiko Seki - Publications, H-index & Citations

Naohiko Seki

chiba university

77H指数

499论文数

2.1W被引数

收录论文 174

发表时间

AKT Inhibitor Capivasertib as a Target for Osimertinib Combination Therapy in Lung Adenocarcinoma with EGFR Mutation AKT抑制剂Capivasertib作为EGFR突变型肺腺癌中Osimertinib联合治疗的目标

Genes

IF2.8

2026-09-20

OAAI

Takuya Tokunaga; Yuka Ishihara; Aya Harada Takeda; Yuya Tomioka; Ayako Nagata; Mayuko Kato; Takayuki Suetsugu; Keiko Mizuno; Kazuhiro Ueda; Naohiko Seki

The microRNA Expression Signature of Lung Adenocarcinoma Harboring EGFR Mutations: Identification of Therapeutic Targets for EGFR-TKI Combination Therapy 肺腺癌中携带EGFR突变的microRNA表达谱：鉴定EGFR-TKI联合疗法的治疗靶点

International Journal of Molecular Sciences

IF4.9

2026-08-12

OAAI

Takuya Tokunaga; Yuya Tomioka; Aya Harada Takeda; Yuka Ishihara; Ayako Nagata; Mayuko Kato; Takayuki Suetsugu; Keiko Mizuno; Masaya Aoki; Kazuhiro Ueda; Naohiko Seki

MicroRNA Signatures of Fulvestrant-Treated Luminal Breast Cancer Cells: Identification of Therapeutic Targets Regulated by miR-374b-5p 氟维司群处理的腔型乳腺癌细胞的微小RNA特征：鉴定由miR-374b-5p调控的治疗靶点

International Journal of Molecular Sciences

IF4.9

2026-07-30

OAAI

Ayako Nagata; Yuya Tomioka; Ryutaro Yasudome; Hiroko Toda; Takuya Tokunaga; Yuki Nagata; Mayuko Kato; Yoshiaki Shinden; Akihiro Nakajo; Naohiko Seki

MEK1 as a Synthetic Lethal Target with Cabozantinib in Renal Cell Carcinoma: Insights from CRISPR/Cas9 Screening MEK1作为与卡博替尼协同致死的靶点在肾细胞癌中的应用：来自CRISPR/Cas9筛选的见解

Genes

IF2.8

2026-07-12

OAAI

Hirofumi Yoshino; Ikumi Fukuda; Hideki Enokida; Naohiko Seki; Yusuke Goto

Identification of Tumor-Suppressive miR-30a-3p Controlled Genes: ANLN as a Therapeutic Target in Breast Cancer

non coding rna research

IF3

2024-11-30

OAAI

Mitsueda, Reiko; Nagata, Ayako; Toda, Hiroko; Tomioka, Yuya; Yasudome, Ryutaro; Kato, Mayuko; Shinden, Yoshiaki; Nakajo, Akihiro; Seki, Naohiko

The Molecular Pathogenesis of Tumor-Suppressive miR-486-5p and miR-486-3p Target Genes: GINS4 Facilitates Aggressiveness in Lung Adenocarcinoma

CELLS

IF5.2

2023-07-18

OAAI

Tomioka, Yuya; Suetsugu, Takayuki; Seki, Naohiko; Tanigawa, Kengo; Hagihara, Yoko; Shinmura, Masahiro; Asai, Shunichi; Kikkawa, Naoko; Inoue, Hiromasa; Mizuno, Keiko

MiR-15b-5p inhibits castration-resistant growth of prostate cancer cells by targeting the muscarinic cholinergic receptor CHRM3

FEBS LETTERS

IF3

2023-02-20

PREAI

Asai, Shunichi; Goto, Yusuke; Tanigawa, Kengo; Tomioka, Yuya; Kato, Mayuko; Mizuno, Keiko; Sakamoto, Shinichi; Seki, Naohiko

MicroRNA signature of small-cell lung cancer after treatment failure: impact on oncogenic targets by miR-30a-3p control

MOLECULAR ONCOLOGY

IF4.5

2022-11-23

OAAI

Tanigawa, Kengo; Misono, Shunsuke; Mizuno, Keiko; Asai, Shunichi; Suetsugu, Takayuki; Uchida, Akifumi; Kawano, Minami; Inoue, Hiromasa; Seki, Naohiko

MicroRNA-874 targets phosphomevalonate kinase and inhibits cancer cell growth via the mevalonate pathway

SCIENTIFIC REPORTS

IF3.9

2022-11-02

OAAI

Aersilan, Alimasi; Hashimoto, Naoko; Yamagata, Kazuyuki; Yokoyama, Masataka; Nakayama, Akitoshi; Shi, Xiaoyan; Nagano, Hidekazu; Sakuma, Ikki; Nohata, Nijiro; Kinoshita, Takashi; Seki, Naohiko; Rahmutulla, Bahityar; Kaneda, Atsushi; Zhahara, Siti Nurul; Gong, Yingbo; Nishimura, Motoi; Kawauchi, Shoichiro; Kawakami, Eiryo; Tanaka, Tomoaki

Impact of miR-1/miR-133 Clustered miRNAs: PFN2 Facilitates Malignant Phenotypes in Head and Neck Squamous Cell Carcinoma

BIOMEDICINES

IF3.9

2022-03-12

OAAI

Asai, Shunichi; Koma, Ayaka; Nohata, Nijiro; Kinoshita, Takashi; Kikkawa, Naoko; Kato, Mayuko; Minemura, Chikashi; Uzawa, Katsuhiro; Hanazawa, Toyoyuki; Seki, Naohiko

Regulation of Oncogenic Targets by Tumor-Suppressive miR-150-3p in Lung Squamous Cell Carcinoma 肺鳞癌中肿瘤抑制miR-150-3p对致癌靶标的调控

BIOMEDICINES

IF3.9

2021-12-11

OAAI

Mizuno, Keiko; Tanigawa, Kengo; Misono, Shunsuke; Suetsugu, Takayuki; Sanada, Hiroki; Uchida, Akifumi; Kawano, Minami; Machida, Kentaro; Asai, Shunichi; Moriya, Shogo; Inoue, Hiromasa; Seki, Naohiko

Isoform-specific and signaling-dependent propagation of acute myeloid leukemia by Wilms tumor 1

CELL REPORTS

IF6.9

2021-04-01

OAAI

Potluri, Sandeep; Assi, Salam A.; Chin, Paulynn S.; Coleman, Dan J. L.; Pickin, Anna; Moriya, Shogo; Seki, Naohiko; Heidenreich, Olaf; Cockerill, Peter N.; Bonifer, Constanze

Regulation of Oncogenic Targets by the Tumor-Suppressive miR-139 Duplex (miR-139-5p and miR-139-3p) in Renal Cell Carcinoma 肾细胞癌中肿瘤抑制miR-139双链体 (miR-139-5p和miR-139-3p) 对致癌靶标的调节

BIOMEDICINES

IF3.9

2020-12-12

OAAI

Okada, Reona; Goto, Yusuke; Yamada, Yasutaka; Kato, Mayuko; Asai, Shunichi; Moriya, Shogo; Ichikawa, Tomohiko; Seki, Naohiko

FAM64A: A Novel Oncogenic Target of Lung Adenocarcinoma Regulated by Both Strands ofmiR-99a(miR-99a-5pandmiR-99a-3p)

CELLS

IF5.2

2020-09-11

OAAI

Mizuno, Keiko; Tanigawa, Kengo; Nohata, Nijiro; Misono, Shunsuke; Okada, Reona; Asai, Shunichi; Moriya, Shogo; Suetsugu, Takayuki; Inoue, Hiromasa; Seki, Naohiko

RNA-sequence-based microRNA expression signature in breast cancer: tumor-suppressive miR-101-5p regulates molecular pathogenesis

MOLECULAR ONCOLOGY

IF4.5

2019-12-29

OAAI

Toda, Hiroko; Seki, Naohiko; Kurozumi, Sasagu; Shinden, Yoshiaki; Yamada, Yasutaka; Nohata, Nijiro; Moriya, Shogo; Idichi, Tetsuya; Maemura, Kosei; Fujii, Takaaki; Horiguchi, Jun; Kijima, Yuko; Natsugoe, Shoji

Regulation of Oncogenic Targets by miR-99a-3p (Passenger Strand of miR-99a-Duplex) in Head and Neck Squamous Cell Carcinoma

CELLS

IF5.2

2019-11-28

OAAI

Okada, Reona; Koshizuka, Keiichi; Yamada, Yasutaka; Moriya, Shogo; Kikkawa, Naoko; Kinoshita, Takashi; Hanazawa, Toyoyuki; Seki, Naohiko

Aberrantly expressed PLOD1 promotes cancer aggressiveness in bladder cancer: a potential prognostic marker and therapeutic target

MOLECULAR ONCOLOGY

IF4.5

2019-06-27

OAAI

Yamada, Yasutaka; Kato, Mayuko; Arai, Takayuki; Sanada, Hiroki; Uchida, Akifumi; Misono, Shunsuke; Sakamoto, Shinichi; Komiya, Akira; Ichikawa, Tomohiko; Seki, Naohiko

Pirin: a potential novel therapeutic target for castration-resistant prostate cancer regulated by miR-455-5p

MOLECULAR ONCOLOGY

IF4.5

2018-12-21

OAAI

Arai, Takayuki; Kojima, Satoko; Yamada, Yasutaka; Sugawara, Sho; Kato, Mayuko; Yamazaki, Kazuto; Naya, Yukio; Ichikawa, Tomohiko; Seki, Naohiko

Regulation of NCAPG by miR-99a-3p (passenger strand) inhibits cancer cell aggressiveness and is involved in CRPC

CANCER RESEARCH

IF16.6

2018-07-01

PREAI

Arai, Takayuki; Okato, Atsushi; Yamada, Yasutaka; Sugawara, Sho; Kurozumi, Akira; Kojima, Satoko; Naya, Yukio; Ichikawa, Tomohiko; Seki, Naohiko