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Q

Quentin Le Grand

university of bordeaux
H指数:10
被引数:4,056

个人简介

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教育背景

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荣誉奖项

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Fibronectin mediates APOE4-driven blood–brain barrier dysfunction in Alzheimer’s disease

纤连蛋白介导APOE4驱动的阿尔茨海默病血脑屏障功能障碍

Nature Aging
IF19.4
2026-09-110
OAAI
Prabesh Bhattarai; Elanur Yilmaz; Elif Öykü Cakir; Huseyin Tayran; Imdadul Haq; Dylan Murphy; Jonah Nadelmann Keller; Quentin Le Grand; Jacqueline O. Eschbach; Hilal Celikkaya; Mehmet I. Cosacak; Hande Yüceer Korkmaz; Annie J. Lee; Verena Haage; Yiyi Ma; Xue Wang; Nastasia Nelson; Weilin Lin; Yixin Zhang; Bengisu Turgutalp; Sherida M. de Leeuw; Ronak Patel; Dörthe Jülich; Özkan İş; Scott A. Holley; Philip L. De Jager; Uwe Freudenberg; Carsten Werner; Peter St George-Hyslop; Nilüfer Ertekin-Taner; Stéphanie Debette; Fanny M. Elahi; Elizabeth S. Fisher; Hemali Phatnani; Andrew F. Teich; Kate Tubbesing; Taylor Bertucci; Sally Temple; Tal Nuriel; Badri N. Vardarajan; Richard Mayeux; Caghan Kizil
Genome-wide association analyses highlight the neuronal contribution to multiple sclerosis susceptibility

全基因组关联分析突出了神经元对多发性硬化易感性的贡献

Nature Genetics
IF29
2026-09-070
PRE
Lu Zeng; Atlas Khan; Kathryn C. Fitzgerald; Tsering Lama; Jessy Chen; Ruixi Li; Ellen A. Tsai; Ketian Yu; Tanuja Chitnis; Howard L. Weiner; Quentin Le Grand; Stéphanie Debette; Gao Wang; Masashi Fujita; Peter A. Calabresi; Frauke Zipp; Mariko Taga; Krzysztof Kiryluk; Philip L. De Jager
Molecular biomarkers in stroke recovery: Consensus-based core recommendations from the fourth Stroke Recovery and Rehabilitation Roundtable

卒中恢复中的分子生物标志物：第四届卒中恢复与康复圆桌会议的共识性核心建议

International Journal of Stroke
IF8.7
2026-08-180
PRE
Matthew A Edwardson; Robynne G Braun; Chad M Aldridge; Rufus Akinyemi; Stefan T Engelter; Israel Fernández-Cadenas; Cristina Gallego-Fabrega; Quentin Le Grand; Jane Maguire; Alexander H Nave; Rajiv Ratan; Bradford B Worrall; Huichun Xu; Amy Brodtmann; Steven C Cramer; Kathryn S Hayward; Arne G Lindgren
Author Correction: UK Biobank at 20 — a growing, global resource for dementia research

作者勘误：英国生物银行20周年——一个不断增长的全球痴呆症研究资源

Nature Reviews Neurology
IF33.1
2026-04-290
PRE
Paul M. Matthews; Naomi E. Allen; Stephanie Debette; Aiden Doherty; Gwenaëlle Douaud; Eugene P. Duff; Paul Elliott; Evelynne S. Fulda; Anastasia Ilina; Quentin Le Grand; Adam J. Lewandowski; Rebecca Mahoney; Karla Miller; Cecilia Rodriguez; Martin K. Rutter; Cynthia Sandor; Rebecca Sims; Stephen M. Smith; Chaoyue Wang
Whole genome sequencing analysis of over 3500 individuals dementia-free over 85 years old

对超过3500名85岁以上无痴呆个体进行全基因组测序分析

JOURNAL OF ALZHEIMERS DISEASE
IF3.1
2026-04-230
PRE
Gina M. Peloso; Dongyu Wang; Sabrina M. Abbruzzese; Joshua C. Bis; Seung Hoan Choi; Alexa Beiser; Jan Bressler; Josée Dupuis; Alison E. Fohner; Mohsen Ghanbari; Richard A. Gibbs; Nancy Heard-Costa; M. Arfan Ikram; Paul Lacaze; Quentin Le Grand; Oscar L. Lopez; Thomas H. Mosley; Moeen Riaz; Aïcha Soumaré; Amber Yaqub; Eric Boerwinkle; Bruce M. Psaty; Myriam Fornage; ; Sudha Seshadri; Anita L DeStefano
UK Biobank at 20 — a growing, global resource for dementia research

英国生物银行20周年——一个不断增长、全球性的痴呆症研究资源

Nature Reviews Neurology
IF33.1
2026-04-140
PRE
Paul M. Matthews; Naomi E. Allen; Stephanie Debette; Aiden Doherty; Gwenaëlle Douaud; Eugene P. Duff; Paul Elliott; Evelynne S. Fulda; Anastasia Illina; Quentin Le Grand; Adam J. Lewandowski; Rebecca Mahoney; Karla Miller; Cecilia Rodriguez; Martin K. Rutter; Cynthia Sandor; Rebecca Sims; Stephen M. Smith; Chaoyue Wang
Proteogenomics in cerebrospinal fluid and plasma reveals new biological fingerprint of cerebral small vessel disease

脑脊液和血浆蛋白质组学揭示脑小血管病新的生物指纹

Nature Aging
IF19.4
2025-11-200
OAAI
Ilana Caro; Daniel Western; Shinichi Namba; Na Sun; Shuji Kawaguchi; Yunye He; Masashi Fujita; Gennady Roshchupkin; Tim D’Aoust; Marie-Gabrielle Duperron; Muralidharan Sargurupremraj; Ami Tsuchida; Masaru Koido; Marziehsadat Ahmadi; Chengran Yang; Jigyasha Timsina; Laura Ibanez; Koichi Matsuda; Yutaka Suzuki; Yoshiya Oda; Akinori Kanai; Pouria Jandaghi; Markus Munter; Daniel Auld; Iana Astafeva; Raquel Puerta; Jerome I. Rotter; Bruce M. Psaty; Joshua C. Bis; WT Longstreth; Thierry Couffinhal; Pablo García-González; Vanesa Pytel; Marta Marquié; Amanda Cano; Mercè Boada; Marc Joliot; Mark Lathrop; Quentin Le Grand; Lenore J. Launer; Joanna M. Wardlaw; Myriam Heiman; Agustin Ruiz; Paul M. Matthews; Sudha Seshadri; Myriam Fornage; Hieab Adams; Aniket Mishra; David-Alexandre Trégouët; Yukinori Okada; Manolis Kellis; Philip L. De Jager; Christophe Tzourio; Yoichiro Kamatani; Fumihiko Matsuda; Carlos Cruchaga; Stéphanie Debette
Polygenic score integrating neurodegenerative and vascular risk informs dementia risk stratification

多基因评分整合神经退行性和血管性风险，为痴呆风险分层提供信息

ALZHEIMERS & DEMENTIA
IF11.1
2025-03-050
OAAI
D'Aoust, T; Clocchiatti-Tuozzo, S; Rivier, CA; Mishra, A; Hachiya, T; Grenier-Boley, B; Soumare, A; Duperron, MG; Le Grand, Q; Bouteloup, V; Proust-Lima, C; Samieri, C; Neuffer, J; Sargurupremraj, M; Chene, G; Helmer, C; Thibault, M; Amouyel, P; Lambert, JC; Kamatani, Y; Jacqmin-Gadda, H; Tregouet, DA; Inouye, M; Dufouil, C; Falcone, GJ; Debette, S
Association of LIfestyle for BRAin health risk score (LIBRA) and genetic susceptibility with incident dementia and cognitive decline

生活方式对脑健康风险评分 (LIBRA) 和遗传易感性与痴呆和认知能力下降的关联

ALZHEIMERS & DEMENTIA
IF11.1
2024-05-221
OA
Neuffer, Jeanne; Wagner, Maude; Moreno, Elisa; Le Grand, Quentin; Mishra, Aniket; Tregouet, David-Alexandre; Leffondre, Karen; Proust-Lima, Cecile; Foubert-Samier, Alexandra; Berr, Claudine; Tzourio, Christophe; Helmer, Catherine; Debette, Stephanie; Samieri, Cecilia
Genetic variants for head size share genes and pathways with cancer

头部大小的遗传变异与癌症共享基因和途径

CELL REPORTS MEDICINE
IF10.6
2024-05-010
OAAI
Knol, Maria J.; Poot, Raymond A.; Evans, Tavia E.; Satizabal, Claudia L.; Mishra, Aniket; Sargurupremraj, Muralidharan; van der Auwera, Sandra; Duperron, Marie-Gabrielle; Jian, Xueqiu; Hostettler, Isabel C.; Van Dam-Nolen, Dianne H. K.; Lamballais, Sander; Pawlak, Mikolaj A.; Lewis, Cora E.; Carrion-Castillo, Amaia; van Erp, Theo G. M.; Reinbold, Celine S.; Shin, Jean; Scholz, Markus; Haberg, Asta K.; Kampe, Anders; Li, Gloria H. Y.; Avinun, Reut; Atkins, Joshua R.; Hsu, Fang-Chi; Amod, Alyssa R.; Lam, Max; Tsuchida, Ami; Teunissen, Mariel W. A.; Aygun, Nil; Patel, Yash; Liang, Dan; Beiser, Alexa S.; Beyer, Frauke; Bis, Joshua C.; Bos, Daniel; Bryan, R. Nick; Buelow, Robin; Caspers, Svenja; Catheline, Gwenaelle; Cecil, Charlotte A. M.; Dalvie, Shareefa; Dartigues, Jean-Francois; DeCarli, Charles; Enlund-Cerullo, Maria; Ford, Judith M.; Franke, Barbara; Freedman, Barry, I; Friedrich, Nele; Green, Melissa J.; Haworth, Simon; Helmer, Catherine; Hoffmann, Per; Homuth, Georg; Ikram, M. Kamran; Jack, Clifford R., Jr.; Jahanshad, Neda; Jockwitz, Christiane; Kamatani, Yoichiro; Knodt, Annchen R.; Li, Shuo; Lim, Keane; Longstreth, W. T.; Macciardi, Fabio; Makitie, Outi; Mazoyer, Bernard; Medland, Sarah E.; Miyamoto, Susumu; Moebus, Susanne; Mosley, Thomas H.; Muetzel, Ryan; Muehleisen, Thomas W.; Nagata, Manabu; Nakahara, Soichiro; Palmer, Nicholette D.; Pausova, Zdenka; Preda, Adrian; Quide, Yann; Reay, William R.; Roshchupkin, Gennady, V; Schmidt, Reinhold; Schreiner, Pamela J.; Setoh, Kazuya; Shapland, Chin Yang; Sidney, Stephen; St Pourcain, Beate; Stein, Jason L.; Tabara, Yasuharu; Teumer, Alexander; Uhlmann, Anne; van der Lugt, Aad; Vernooij, Meike W.; Werring, David J.; Windham, B. Gwen; Witte, A. Veronica; Wittfeld, Katharina; Yang, Qiong; Yoshida, Kazumichi; Brunner, Han G.; Le Grand, Quentin; Sim, Kang; Stein, Dan J.; Bowden, Donald W.; Cairns, Murray J.; Hariri, Ahmad R.; Cheung, Ching-Lung; Andersson, Sture; Villringer, Arno; Paus, Tomas; Cichon, Sven; Calhoun, Vince D.; Crivello, Fabrice; Launer, Lenore J.; White, Tonya; Koudstaal, Peter J.; Houlden, Henry; Fornage, Myriam; Matsuda, Fumihiko; Grabe, Hans J.; Ikram, M. Arfan; Debette, Stephanie; Thompson, Paul M.; Seshadri, Sudha; Adams, Hieab H. H.
Genomics of perivascular space burden unravels early mechanisms of cerebral small vessel disease

血管周围空间负荷的基因组学阐明脑小血管病的早期机制

NATURE MEDICINE
IF50
2023-04-1733
OAAI
Duperron, Marie-Gabrielle E.; Knol, Maria; Le Grand, Quentin; Evans, Tavia; Mishra, Aniket; Tsuchida, Ami; Roshchupkin, Gennady; Konuma, Takahiro; Tregouet, David-Alexandre; Romero, Jose Rafael; Frenzel, Stefan; Luciano, Michelle D.; Hofer, Edith; Bourgey, Mathieu; Dueker, Nicole M.; Delgado, Pilar; Hilal, Saima; Tankard, Rick; Dubost, Florian J.; Shin, Jean; Saba, Yasaman E.; Armstrong, Nicola; Bordes, Constance; Bastin, Mark; Beiser, Alexa; Brodaty, Henry; Buelow, Robin; Carrera, Caty J.; Chen, Christopher G.; Cheng, Ching-Yu J.; Deary, Ian; Gampawar, Piyush; Himali, Jayandra; Jiang, Jiyang; Kawaguchi, Takahisa; Li, Shuo; Macalli, Melissa; Marquis, Pascale; Morris, Zoe; Maniega, Susana Munoz; Miyamoto, Susumu; Okawa, Masakazu; Paradise, Matthew; Parva, Pedram; Rundek, Tatjana; Sargurupremraj, Muralidharan; Schilling, Sabrina; Setoh, Kazuya; Soukarieh, Omar; Tabara, Yasuharu N.; Teumer, Alexander C.; Thalamuthu, Anbupalam W.; Trollor, Julian; Hernandez, Maria C. Valdes; Vernooij, Meike; Voelker, Uwe J.; Wittfeld, Katharina; Wong, Tien Yin; Wright, Margaret; Zhang, Junyi; Zhao, Wanting S.; Zhu, Yi-Cheng; Schmidt, Helena; Sachdev, Perminder; Wen, Wei L.; Yoshida, Kazumichi L.; Joutel, Anne; Satizabal, Claudia; Sacco, Ralph; Bourque, Guillaume; Lathrop, Mark; Paus, Tomas; Fernandez-Cadenas, Israel; Yang, Qiong; Mazoyer, Bernard; Boutinaud, Philippe J.; Okada, Yukinori A.; Grabe, Hans; Mather, Karen; Schmidt, Reinhold; Joliot, Marc; Ikram, M. Arfan; Matsuda, Fumihiko M.; Tzourio, Christophe; Wardlaw, Joanna; Seshadri, Sudha; Adams, Hieab H. H.; Debette, Stephanie
Stroke genetics informs drug discovery and risk prediction across ancestries
Nature
IF48.5
2022-09-300
OAAI
Aniket Mishra; Rainer Malik; Tsuyoshi Hachiya; Tuuli Jürgenson; Shinichi Namba; Daniel C. Posner; Frederick K. Kamanu; Masaru Koido; Quentin Le Grand; Mingyang Shi; Yunye He; Marios K. Georgakis; Ilana Caro; Kristi Krebs; Yi-Ching Liaw; Felix C. Vaura; Kuang Lin; Bendik Slagsvold Winsvold; Vinodh Srinivasasainagendra; Livia Parodi; Hee-Joon Bae; Ganesh Chauhan; Michael R. Chong; Liisa Tomppo; Rufus Akinyemi; Gennady V. Roshchupkin; Naomi Habib; Yon Ho Jee; Jesper Qvist Thomassen; Vida Abedi; Jara Cárcel-Márquez; Marianne Nygaard; Hampton L. Leonard; Chaojie Yang; Ekaterina Yonova-Doing; Maria J. Knol; Adam J. Lewis; Renae L. Judy; Tetsuro Ago; Philippe Amouyel; Nicole D. Armstrong; Mark K. Bakker; Traci M. Bartz; David A. Bennett; Joshua C. Bis; Constance Bordes; Sigrid Børte; Anael Cain; Paul M. Ridker; Kelly Cho; Zhengming Chen; Carlos Cruchaga; John W. Cole; Phil L. de Jager; Rafael de Cid; Matthias Endres; Leslie E. Ferreira; Mirjam I. Geerlings; Natalie C. Gasca; Vilmundur Gudnason; Jun Hata; Jing He; Alicia K. Heath; Yuk-Lam Ho; Aki S. Havulinna; Jemma C. Hopewell; Hyacinth I. Hyacinth; Michael Inouye; Mina A. Jacob; Christina E. Jeon; Christina Jern; Masahiro Kamouchi; Keith L. Keene; Takanari Kitazono; Steven J. Kittner; Takahiro Konuma; Amit Kumar; Paul Lacaze; Lenore J. Launer; Keon-Joo Lee; Kaido Lepik; Jiang Li; Liming Li; Ani Manichaikul; Hugh S. Markus; Nicholas A. Marston; Thomas Meitinger; Braxton D. Mitchell; Felipe A. Montellano; Takayuki Morisaki; Thomas H. Mosley; Mike A. Nalls; Børge G. Nordestgaard; Martin J. O’Donnell; Yukinori Okada; N. Charlotte Onland-Moret; Bruce Ovbiagele; Annette Peters; Bruce M. Psaty; Stephen S. Rich; Jonathan Rosand; Marc S. Sabatine; Ralph L. Sacco; Danish Saleheen; Else Charlotte Sandset; Veikko Salomaa; Muralidharan Sargurupremraj; Makoto Sasaki; Claudia L. Satizabal; Carsten O. Schmidt; Atsushi Shimizu; Nicholas L. Smith; Kelly L. Sloane; Yoichi Sutoh; Yan V. Sun; Kozo Tanno; Steffen Tiedt; Turgut Tatlisumak; Nuria P. Torres-Aguila; Hemant K. Tiwari; David-Alexandre Trégouët; Stella Trompet; Anil Man Tuladhar; Anne Tybjærg-Hansen; Marion van Vugt; Riina Vibo; Shefali S. Verma; Kerri L. Wiggins; Patrik Wennberg; Daniel Woo; Peter W. F. Wilson; Huichun Xu; Qiong Yang; Kyungheon Yoon; Iona Y. Millwood; Christian Gieger; Toshiharu Ninomiya; Hans J. Grabe; J. Wouter Jukema; Ina L. Rissanen; Daniel Strbian; Young Jin Kim; Pei-Hsin Chen; Ernst Mayerhofer; Joanna M. M. Howson; Marguerite R. Irvin; Hieab Adams; Sylvia Wassertheil-Smoller; Kaare Christensen; Mohammad A. Ikram; Tatjana Rundek; Bradford B. Worrall; G. Mark Lathrop; Moeen Riaz; Eleanor M. Simonsick; Janika Kõrv; Paulo H. C. França; Ramin Zand; Kameshwar Prasad; Ruth Frikke-Schmidt; Frank-Erik de Leeuw; Thomas Liman; Karl Georg Haeusler; Ynte M. Ruigrok; Peter Ulrich Heuschmann; W. T. Longstreth; Keum Ji Jung; Lisa Bastarache; Guillaume Paré; Scott M. Damrauer; Daniel I. Chasman; Jerome I. Rotter; Christopher D. Anderson; John-Anker Zwart; Teemu J. Niiranen; Myriam Fornage; Yung-Po Liaw; Sudha Seshadri; Israel Fernández-Cadenas; Robin G. Walters; Christian T. Ruff; Mayowa O. Owolabi; Jennifer E. Huffman; Lili Milani; Yoichiro Kamatani; Martin Dichgans; Stephanie Debette
Genomic Studies Across the Lifespan Point to Early Mechanisms Determining Subcortical Volumes
BIOLOGICAL PSYCHIATRY-COGNITIVE NEUROSCIENCE AND NEUROIMAGING
IF4.8
2022-06-014
OAAI
Le Grand, Quentin; Satizabal, Claudia L.; Sargurupremraj, Muralidharan; Mishra, Aniket; Soumare, Aicha; Laurent, Alexandre; Crivello, Fabrice; Tsuchida, Ami; Shin, Jean; Macalli, Melissa; Singh, Baljeet; Beiser, Alexa S.; DeCarli, Charles; Fletcher, Evan; Paus, Tomas; Lathrop, Mark; Adams, Hieab H. H.; Bis, Joshua C.; Seshadri, Sudha; Tzourio, Christophe; Mazoyer, Bernard; Debette, Stephanie
Cerebral small vessel disease genomics and its implications across the lifespan

脑小血管疾病基因组学及其在整个生命周期中的意义

NATURE COMMUNICATIONS
IF15.7
2020-12-08106
OAAI
Sargurupremraj, Muralidharan; Suzuki, Hideaki; Jian, Xueqiu; Sarnowski, Chloe; Evans, Tavia E.; Bis, Joshua C.; Eiriksdottir, Gudny; Sakaue, Saori; Terzikhan, Natalie; Habes, Mohamad; Zhao, Wei; Armstrong, Nicola J.; Hofer, Edith; Yanek, Lisa R.; Hagenaars, Saskia P.; Kumar, Rajan B.; van den Akker, Erik B.; McWhirter, Rebekah E.; Trompet, Stella; Mishra, Aniket; Saba, Yasaman; Satizabal, Claudia L.; Beaudet, Gregory; Petit, Laurent; Tsuchida, Ami; Zago, Laure; Schilling, Sabrina; Sigurdsson, Sigurdur; Gottesman, Rebecca F.; Lewis, Cora E.; Aggarwal, Neelum T.; Lopez, Oscar L.; Smith, Jennifer A.; Hernandez, Maria C. Valdes; van der Grond, Jeroen; Wright, Margaret J.; Knol, Maria J.; Dorr, Marcus; Thomson, Russell J.; Bordes, Constance; Le Grand, Quentin; Duperron, Marie-Gabrielle; Smith, Albert, V; Knopman, David S.; Schreiner, Pamela J.; Evans, Denis A.; Rotter, Jerome, I; Beiser, Alexa S.; Maniega, Susana Munoz; Beekman, Marian; Trollor, Julian; Stott, David J.; Vernooij, Meike W.; Wittfeld, Katharina; Niessen, Wiro J.; Soumare, Aicha; Boerwinkle, Eric; Sidney, Stephen; Turner, Stephen T.; Davies, Gail; Thalamuthu, Anbupalam; Volker, Uwe; van Buchem, Mark A.; Bryan, R. Nick; Dupuis, Josee; Bastin, Mark E.; Ames, David; Teumer, Alexander; Amouyel, Philippe; Kwok, John B.; Bulow, Robin; Deary, Ian J.; Schofield, Peter R.; Brodaty, Henry; Jiang, Jiyang; Tabara, Yasuharu; Setoh, Kazuya; Miyamoto, Susumu; Yoshida, Kazumichi; Nagata, Manabu; Kamatani, Yoichiro; Matsuda, Fumihiko; Psaty, Bruce M.; Bennett, David A.; De Jager, Philip L.; Mosley, Thomas H.; Sachdev, Perminder S.; Schmidt, Reinhold; Warren, Helen R.; Evangelou, Evangelos; Tregouet, David-Alexandre; Ikram, Mohammad A.; Wen, Wei; DeCarli, Charles; Srikanth, Velandai K.; Jukema, J. Wouter; Slagboom, Eline P.; Kardia, Sharon L. R.; Okada, Yukinori; Mazoyer, Bernard; Wardlaw, Joanna M.; Nyquist, Paul A.; Mather, Karen A.; Grabe, Hans J.; Schmidt, Helena; Van Duijn, Cornelia M.; Gudnason, Vilmundur; Longstreth, William T., Jr.; Launer, Lenore J.; Lathrop, Mark; Seshadri, Sudha; Tzourio, Christophe; Adams, Hieab H.; Matthews, Paul M.; Fornage, Myriam; Debette, Stephanie

研究方向

暂未获取到该数据
S
Stéphanie Debette
H 指数:94论文数:528被引数:4.2万
A
Aniket Mishra
H 指数:31论文数:112被引数:8,295
M
Muralidharan Sargurupremraj
H 指数:31论文数:96被引数:8,796
A
Ami Tsuchida
H 指数:14论文数:53被引数:1,476
C
Christophe Tzourio
H 指数:124论文数:794被引数:8.8万
A
Alexa Beiser
H 指数:131论文数:672被引数:6.9万
P
Philip L. De Jager
H 指数:147论文数:1,086被引数:10.1万
J
Joshua C. Bis
H 指数:126论文数:666被引数:7.7万
D
David‐Alexandre Trégouët
H 指数:81论文数:467被引数:3.3万
C
Claudia L. Satizábal
H 指数:54论文数:402被引数:2.0万