未登录 Oxidised Apolipoprotein Peptidome Characterises Metabolic Dysfunction-Associated Steatotic Liver Disease Mocciaro, Gabriele; George, Amy L.; Allison, Michael; Frontini, Mattia; Huang-Doran, Isabel; Reiman, Frank; Gribble, Fiona; Griffin, Julian L.; Vidal-Puig, Antonio; Azzu, Vian; Kay, Richard; Vacca, Michele 分享 收藏
Characterization of six clinical drugs and dietary intervention in the nonobese CDAA-HFD mouse model of MASH and progressive fibrosis 非肥胖CDAA-HFD小鼠MASH和进展性纤维化模型的六种临床药物及饮食干预的表征 Nielsen, MH; Nohr-Meldgaard, J; Mollerhoj, MB; Oró, D; Pors, SE; Andersen, MW; Kamzolas, I; Petsalaki, E; Vacca, M; Harder, LM; Perfield, JW; Veidal, S; Hansen, HH; Feigh, M 分享 收藏
Chronic inorganic nitrate supplementation does not improve metabolic health and worsens disease progression in mice with diet-induced obesity 慢性无机硝酸盐补充剂不会改善代谢健康，并会加重饮食诱导肥胖小鼠的疾病进展。 Sowton, AP; Holzner, LMW; Krause, FN; Baxter, R; Mocciaro, G; Krzyzanska, DK; Minnion, M; O'Brien, KA; Harrop, MC; Darwin, PM; Thackray, BD; Vacca, M; Feelisch, M; Griffin, JL; Murray, AJ 分享 收藏
分享 收藏
SMIM1 absence is associated with reduced energy expenditure and excess weight SMIM1缺失与能量消耗减少和超重有关 Stefanucci, Luca; Moslemi, Camous; Tome, Ana R.; Virtue, Samuel; Bidault, Guillaume; Gleadall, Nicholas S.; Watson, Laura P. E.; Kwa, Jing E.; Burden, Frances; Farrow, Samantha; Chen, Ji; Vosa, Urmo; Burling, Keith; Walker, Lindsay; Ord, John; Barker, Peter; Warner, James; Frary, Amy; Renhstrom, Karola; Ashford, Sofie E.; Piper, Jo; Biggs, Gail; Erber, Wendy N.; Hoffman, Gary J.; Schoenmakers, Nadia; Erikstrup, Christian; Rieneck, Klaus; Dziegiel, Morten H.; Ullum, Henrik; Azzu, Vian; Vacca, Michele; Aparicio, Hugo Javier; Hui, Qin; Cho, Kelly; Sun, Yan, V; Wilson, Peter W.; Bayraktar, Omer A.; Vidal-Puig, Antonio; Ostrowski, Sisse R.; Astle, William J.; Olsson, Martin L.; Storry, Jill R.; Pedersen, Ole B.; Ouwehand, Willem H.; Chatterjee, Krishna; Vuckovic, Dragana; Frontini, Mattia 分享 收藏
An unbiased ranking of murine dietary models based on their proximity to human metabolic dysfunction-associated steatotic liver disease (MASLD) 基于与人类代谢功能障碍相关的脂肪变性肝病 (MASLD) 的接近程度，对小鼠饮食模型进行无偏排名 Vacca, Michele; Kamzolas, Ioannis; Harder, Lea Morch; Oakley, Fiona; Trautwein, Christian; Hatting, Maximilian; Ross, Trenton; Bernardo, Barbara; Oldenburger, Anouk; Hjuler, Sara Toftegaard; Ksiazek, Iwona; Linden, Daniel; Schuppan, Detlef; Rodriguez-Cuenca, Sergio; Tonini, Maria Manuela; Castaneda, Tamara R.; Kannt, Aimo; Rodrigues, Cecilia M. P.; Cockell, Simon; Govaere, Olivier; Daly, Ann K.; Allison, Michael; de Lichtenberg, Kristian Honnens; Kim, Yong Ook; Lindblom, Anna; Oldham, Stephanie; Andreasson, Anne-Christine; Schlerman, Franklin; Marioneaux, Jonathon; Sanyal, Arun; Afonso, Marta B.; Younes, Ramy; Amano, Yuichiro; Friedman, Scott L.; Wang, Shuang; Bhattacharya, Dipankar; Simon, Eric; Paradis, Valerie; Burt, Alastair; Grypari, Ioanna Maria; Davies, Susan; Driessen, Ann; Yashiro, Hiroaki; Pors, Susanne; Andersen, Maja Worm; Feigh, Michael; Yunis, Carla; Bedossa, Pierre; Stewart, Michelle; Cater, Heather L.; Wells, Sara; Schattenberg, Joern M.; Anstee, Quentin M.; Tiniakos, Dina; Perfield, James W.; Petsalaki, Evangelia; Davidsen, Peter; Vidal-Puig, Antonio; Anstee, Quentin M.; Daly, Ann K.; Cockell, Simon; Tiniakos, Dina; Bedossa, Pierre; Burt, Alastair; Oakley, Fiona; Cordell, Heather J.; Day, Christopher P.; Wonders, Kristy; Missier, Paolo; McTeer, Matthew; Vale, Luke; Oluboyede, Yemi; Breckons, Matt; Boyle, Jo; Bossuyt, Patrick M.; Zafarmand, Hadi; Vali, Yasaman; Lee, Jenny; Nieuwdorp, Max; Holleboom, Adriaan G.; Angelakis, Athanasios; Verheij, Joanne; Ratziu, Vlad; Clement, Karine; Patino-Navarrete, Rafael; Pais, Raluca; Paradis, Valerie; Schuppan, Detlef; Schattenberg, Joern M.; Surabattula, Rambabu; Myneni, Sudha; Kim, Yong Ook; Straub, Beate K.; Vidal-Puig, Antonio; Vacca, Michele; Rodrigues-Cuenca, Sergio; Allison, Mike; Kamzolas, Ioannis; Petsalaki, Evangelia; Campbell, Mark; Lelliott, Chris J.; Davies, Susan; Oresic, Matej; Hyotylainen, Tuulia; McGlinchey, Aidan; Mato, Jose M.; Millet, Oscar; Dufour, Jean-Francois; Berzigotti, Annalisa; Masoodi, Mojgan; Lange, Naomi F.; Pavlides, Michael; Harrison, Stephen; Neubauer, Stefan; Cobbold, Jeremy; Mozes, Ferenc; Akhtar, Salma; Olodo-Atitebi, Seliat; Banerjee, Rajarshi; Shumbayawonda, Elizabeth; Dennis, Andrea; Andersson, Anneli; Wigley, Ioan; Romero-Gomez, Manuel; Gomez-Gonzalez, Emilio; Ampuero, Javier; Castell, Javier; Gallego-Duran, Rocio; Fernandez-Lizaranzu, Isabel; Montero-Vallejo, Rocio; Karsdal, Morten; Rasmussen, Daniel Guldager Kring; Leeming, Diana Julie; Sinisi, Antonia; Musa, Kishwar; Sandt, Estelle; Tonini, Maria Manuela; Bugianesi, Elisabetta; Rosso, Chiara; Armandi, Angelo; Marra, Fabio; Gastaldelli, Amalia; Svegliati, Gianluca; Boursier, Jerome; Francque, Sven; Vonghia, Luisa; Verrijken, An; Dirinck, Eveline; Driessen, Ann; Ekstedt, Mattias; Kechagias, Stergios; Yki-Jarvinen, Hannele; Porthan, Kimmo; Arola, Johanna; van Mil, Saskia; Papatheodoridis, George; Cortez-Pinto, Helena; Silva, Ana Paula; Rodrigues, Cecilia M. P.; Valenti, Luca; Pelusi, Serena; Petta, Salvatore; Pennisi, Grazia; Miele, Luca; Liguori, Antonio; Geier, Andreas; Rau, Monika; Trautwein, Christian; Reissing, Johanna; Aithal, Guruprasad P.; Francis, Susan; Palaniyappan, Naaventhan; Bradley, Christopher; Hockings, Paul; Schneider, Moritz; Newsome, Philip N.; Hubscher, Stefan; Wenn, David; Magnanensi, Jeremy; Trylesinski, Aldo; Mayo, Rebeca; Alonso, Cristina; Duffin, Kevin; Perfield, James W.; Chen, Yu; Hartman, Mark L.; Yunis, Carla; Miller, Melissa; Chen, Yan; McLeod, Euan James; Ross, Trenton; Bernardo, Barbara; Schoelch, Corinna; Ertle, Judith; Younes, Ramy; Coxson, Harvey; Simon, Eric; Gogain, Joseph; Ostroff, Rachel; Alexander, Leigh; Biegel, Hannah; Kjaer, Mette Skalshoi; Harder, Lea Morch; Al-Sari, Naba; Veidal, Sanne Skovgard; Oldenburger, Anouk; Ellegaard, Jens; Balp, Maria-Magdalena; Jennings, Lori; Martic, Miljen; Loffler, Jurgen; Applegate, Douglas; Torstenson, Richard; Linden, Daniel; Fournier-Poizat, Celine; Llorca, Anne; Kalutkiewicz, Michael; Pepin, Kay; Ehman, Richard; Horan, Gerald; Ho, Gideon; Tai, Dean; Chng, Elaine; Xiao, Teng; Patterson, Scott D.; Billin, Andrew; Doward, Lynda; Twiss, James; Thakker, Paresh; Derdak, Zoltan; Yashiro, Hiroaki; Landgren, Henrik; Lackner, Carolin; Gouw, Annette; Hytiroglou, Prodromos; Govaere, Olivier; Brass, Clifford 分享 收藏
Exploring the impact of the PNPLA3 I148M variant on primary human hepatic stellate cells using 3D extracellular matrix models 使用3D细胞外基质模型探索PNPLA3 I148M变体对原代人肝星状细胞的影响 Caon, Elisabetta; Martins, Maria; Hodgetts, Harry; Blanken, Lieke; Vilia, Maria Giovanna; Levi, Ana; Thanapirom, Kessarin; Al-Akkad, Walid; Abu-Hanna, Jeries; Baselli, Guido; Hall, Andrew R.; Luong, Tu Vinh; Taanman, Jan-Willem; Vacca, Michele; Valenti, Luca; Romeo, Stefano; Mazza, Giuseppe; Pinzani, Massimo; Rombouts, Krista 分享 收藏
Non-alcoholic fatty liver disease is characterised by a reduced polyunsaturated fatty acid transport via free fatty acids and high-density lipoproteins (HDL) Mocciaro, Gabriele; Allison, Michael; Jenkins, Benjamin; Azzu, Vian; Huang-Doran, Isabel; Herrera-Marcos, Luis Vicente; Hall, Zoe; Murgia, Antonio; Susan, Davies; Frontini, Mattia; Vidal-Puig, Antonio; Koulman, Albert; Griff, Julian L.; Vacca, Michele 分享 收藏
Genome-wide association study of non- alcoholic fatty liver and steatohepatitis in a histologically characterised cohort( vol 73, pp 505-515 , 2020 ) Anstee, Quentin M.; Darlay, Rebecca; Cockell, Simon; Meroni, Marica; Govaere, Olivier; Tiniakos, Dina; Burt, Alastair D.; Bedossa, Pierre; Palmer, Jeremy; Liu, Yang-Lin; Aithal, Guruprasad P.; Allison, Michael; Yki-Jarvinen, Hannele; Vacca, Michele; Dufour, Jean-Francois; Invernizzi, Pietro; Prati, Daniele; Ekstedt, Mattias; Kechagias, Stergios; Francque, Sven; Petta, Salvatore; Bugianesi, Elisabetta; Clement, Karine; Ratziu, Vlad; Schattenberg, Joern M.; Valenti, Luca; Day, Christopher P.; Cordell, Heather J.; Daly, Ann K. 分享 收藏
分享 收藏
Macrophage scavenger receptor 1 mediates lipid-induced inflammation in non-alcoholic fatty liver disease 巨噬细胞清道夫受体1介导非酒精性脂肪性肝病中脂质诱导的炎症 Govaere, Olivier; Petersen, Sine Kragh; Martinez-Lopez, Nuria; Wouters, Jasper; Van Haele, Matthias; Mancina, Rosellina M.; Jamialahmadi, Oveis; Bilkei-Gorzo, Orsolya; Lassen, Pierre Bel; Darlay, Rebecca; Peltier, Julien; Palmer, Jeremy M.; Younes, Ramy; Tiniakos, Dina; Aithal, Guruprasad P.; Allison, Michael; Vacca, Michele; Goransson, Melker; Berlinguer-Palmini, Rolando; Clark, James E.; Drinnan, Michael J.; Yki-Jarvinen, Hannele; Dufour, Jean-Francois; Ekstedt, Mattias; Francque, Sven; Petta, Salvatore; Bugianesi, Elisabetta; Schattenberg, Jorn M.; Day, Christopher P.; Cordell, Heather J.; Topal, Baki; Clement, Karine; Romeo, Stefano; Ratziu, Vlad; Roskams, Tania; Daly, Ann K.; Anstee, Quentin M.; Trost, Matthias; Hartlova, Anetta 分享 收藏
Long-chain ceramides are cell non-autonomous signals linking lipotoxicity to endoplasmic reticulum stress in skeletal muscle McNally, Ben D.; Ashley, Dean F.; Haenschke, Lea; Daou, Helene N.; Watt, Nicole T.; Murfitt, Steven A.; MacCannell, Amanda D., V; Whitehead, Anna; Bowen, T. Scott; Sanders, Francis W. B.; Vacca, Michele; Witte, Klaus K.; Davies, Graeme R.; Bauer, Reinhard; Griffin, Julian L.; Roberts, Lee D. 分享 收藏
Transcriptional, epigenetic and metabolic signatures in cardiometabolic syndrome defined by extreme phenotypes 极端表型定义的心脏代谢综合征中的转录，表观遗传和代谢特征 Seyres, Denis; Cabassi, Alessandra; Lambourne, John J.; Burden, Frances; Farrow, Samantha; McKinney, Harriet; Batista, Joana; Kempster, Carly; Pietzner, Maik; Slingsby, Oliver; Thong Huy Cao; Quinn, Paulene A.; Stefanucci, Luca; Sims, Matthew C.; Rehnstrom, Karola; Adams, Claire L.; Frary, Amy; Erguener, Bekir; Kreuzhuber, Roman; Mocciaro, Gabriele; D'Amore, Simona; Koulman, Albert; Grassi, Luigi; Griffin, Julian L.; Ng, Leong Loke; Park, Adrian; Savage, David B.; Langenberg, Claudia; Bock, Christoph; Downes, Kate; Wareham, Nicholas J.; Allison, Michael; Vacca, Michele; Kirk, Paul D. W.; Frontini, Mattia 分享 收藏
RNF43/ZNRF3 loss predisposes to hepatocellular-carcinoma by impairing liver regeneration and altering the liver lipid metabolic ground-state RNF43/ZNRF3丢失通过损害肝再生和改变肝脂质代谢基态而易患肝细胞癌 Belenguer, German; Mastrogiovanni, Gianmarco; Pacini, Clare; Hall, Zoe; Dowbaj, Anna M.; Arnes-Benito, Robert; Sljukic, Aleksandra; Prior, Nicole; Kakava, Sofia; Bradshaw, Charles R.; Davies, Susan; Vacca, Michele; Saeb-Parsy, Kourosh; Koo, Bon-Kyoung; Huch, Meritxell 分享 收藏
β2-spectrin (SPTBN1) as a therapeutic target for diet-induced liver disease and preventing cancer development Β2-血影蛋白 (SPTBN1) 作为饮食诱导的肝病和预防癌症发展的治疗靶点 Rao, Shuyun; Yang, Xiaochun; Ohshiro, Kazufumi; Zaidi, Sobia; Wang, Zhanhuai; Shetty, Kirti; Xiang, Xiyan; Hassan, Md Imtaiyaz; Mohammad, Taj; Latham, Patricia S.; Bao-Ngoc Nguyen; Wong, Linda; Yu, Herbert; Al-Abed, Yousef; Mishra, Bibhuti; Vacca, Michele; Guenigault, Gareth; Allison, Michael E. D.; Vidal-Puig, Antonio; Benhammou, Jihane N.; Alvarez, Marcus; Pajukanta, Paivi; Pisegna, Joseph R.; Mishra, Lopa 分享 收藏
Suppression of insulin-induced gene 1 (INSIG1) function promotes hepatic lipid remodelling and restrains NASH progression 抑制胰岛素诱导基因1 (INSIG1) 功能促进肝脂质重塑并抑制NASH进展 Azzu, Vian; Vacca, Michele; Kamzolas, Ioannis; Hall, Zoe; Leslie, Jack; Carobbio, Stefania; Virtue, Samuel; Davies, Susan E.; Lukasik, Agnes; Dale, Martin; Bohlooly-Y, Mohammad; Acharjee, Animesh; Linden, Daniel; Bidault, Guillaume; Petsalaki, Evangelia; Griffin, Julian L.; Oakley, Fiona; Allison, Michael E. D.; Vidal-Puig, Antonio 分享 收藏
Genome-wide association study of non-alcoholic fatty liver and steatohepatitis in a histologically characterised cohort (vol 12, pg 505, 2020) Anstee, Quentin M.; Darlay, Rebecca; Cockell, Simon; Meroni, Marica; Govaere, Olivier; Tiniakos, Dina; Burt, Alastair D.; Bedossa, Pierre; Palmer, Jeremy; Liu, Yang-Lin; Aithal, Guruprasad P.; Allison, Michael; Yki-Jarvinen, Hannele; Vacca, Michele; Dufour, Jean-Francois; Invernizzi, Pietro; Prati, Daniele; Ekstedt, Mattias; Kechagias, Stergios; Francque, Sven; Petta, Salvatore; Bugianesi, Elisabetta; Clement, Karine; Ratziu, Vlad; Schattenberg, Jorn M.; Valenti, Luca; Day, Christopher P.; Cordell, Heather J.; Daly, Ann K. 分享 收藏
Transcriptomic profiling across the nonalcoholic fatty liver disease spectrum reveals gene signatures for steatohepatitis and fibrosis 跨非酒精性脂肪肝疾病谱的转录组分析揭示了脂肪性肝炎和纤维化的基因特征 Govaere, Olivier; Cockell, Simon; Tiniakos, Dina; Queen, Rachel; Younes, Ramy; Vacca, Michele; Alexander, Leigh; Ravaioli, Federico; Palmer, Jeremy; Petta, Salvatore; Boursier, Jerome; Rosso, Chiara; Johnson, Katherine; Wonders, Kristy; Day, Christopher P.; Ekstedt, Mattias; Oresic, Matej; Darlay, Rebecca; Cordell, Heather J.; Marra, Fabio; Vidal-Puig, Antonio; Bedossa, Pierre; Schattenberg, Joern M.; Clement, Karine; Allison, Michael; Bugianesi, Elisabetta; Ratziu, Vlad; Daly, Ann K.; Anstee, Quentin M. 分享 收藏
The stem/progenitor landscape is reshaped in a mouse model of essential thrombocythemia and causes excess megakaryocyte production 在原发性血小板增多症的小鼠模型中重塑干/祖细胞景观，并导致过量的巨核细胞产生 Prins, Daniel; Park, Hyun Jung; Watcham, Sam; Li, Juan; Vacca, Michele; Bastos, Hugo P.; Gerbaulet, Alexander; Vidal-Puig, Antonio; Gottgens, Berthold; Green, Anthony R. 分享 收藏
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
分享.png){kind=icon}
收藏
未登录.png){kind=icon}