未登录PAM-interacting domain turn-helix 51 motifs can improve Cas9-SpRY activityPAM-interacting domain turn-helix 51 motifs可以增强Cas9-SpRY活性
Eggenschwiler, Reto; Hoffmann, Thomas; Dmytrenko, Oleg; Opitz, Mika; Ackel-Zakour, Marlene; Wang, Pascal; McCallan, Shannon A.; Fraguas-Eggenschwiler, Mariane; Niemann, Heiner; Patronov, Atanas; Beisel, Chase L.; Cantz, Tobias
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收藏An optimized culture system for efficient derivation of porcine expanded potential stem cells from preimplantation embryos and by reprogramming somatic cells一种优化的培养系统,用于从植入前胚胎中有效衍生猪扩增的潜在干细胞,并通过重编程体细胞
Ruan, Degong; Xuan, Yiyi; Tam, Timothy Theodore Ka Ki; Li, Zhuoxuan; Wang, Xiao; Xu, Shao; Herrmann, Doris; Niemann, Heiner; Lai, Liangxue; Gao, Xuefei; Nowak-Imialek, Monika; Liu, Pentao
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收藏Long term study of decellularized and glycan-modified GGTA1-KO porcine heart valves implanted into baboons
Ramm, Robert; Smart, Isabel; Goecke, Tobias; Abicht, Jan; Laengin, Matthias; Lampe, Karen; Hoeffler, Klaus; Magdei, Mikhail; Cebotari, Serghei; Tudorache, Igor; Petersen, Bjoern; Moussavi, Amir; Boretius, Susann; Weinhart, Marie; Hinkel, Rabea; Buettner, Falk F. R.; Niemann, Heiner; Haverich, Axel; Hilfiker, Andres
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收藏Species-Specific Paternal Age Effects and Sperm Methylation Levels of Developmentally Important Genes
Prell, Andreas; Sen, Mustafa Orkun; Potabattula, Ramya; Bernhardt, Laura; Dittrich, Marcus; Hahn, Thomas; Schorsch, Martin; Zacchini, Federica; Ptak, Grazyna Ewa; Niemann, Heiner; Haaf, Thomas
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收藏Immunological and functional features of decellularized xenogeneic heart valves after transplantation into GGTA1-KO pigs
Ramm, Robert; Goecke, Tobias; Koehler, Peter; Tudorache, Igor; Cebotari, Serghei; Ciubotaru, Anatol; Sarikouch, Samir; Hoeffler, Klaus; Bothe, Friederike; Petersen, Bjorn; Haverich, Axel; Niemann, Heiner; Hilfiker, Andres
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收藏Increasing methylation of sperm rDNA and other repetitive elements in the aging male mammalian germline
Potabattula, Ramya; Zacchini, Federica; Ptak, Grazyna Ewa; Dittrich, Marcus; Mueller, Tobias; El Hajj, Nady; Hahn, Thomas; Drummer, Charis; Behr, Ruediger; Lucas-Hahn, Andrea; Niemann, Heiner; Schorsch, Martin; Haaf, Thomas
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收藏Triple (GGTA1, CMAH, B2M) modified pigs expressing an SLA class Ilow phenotype-Effects on immune status and susceptibility to human immune responses
Hein, Rabea; Sake, Hendrik J.; Pokoyski, Claudia; Hundrieser, Joachim; Brinkmann, Antje; Baars, Wiebke; Nowak-Imialek, Monika; Lucas-Hahn, Andrea; Figueiredo, Constanca; Schuberth, Hans-Joachim; Niemann, Heiner; Petersen, Bjoern; Schwinzer, Reinhard
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收藏Establishment of porcine and human expanded potential stem cells猪和人扩增潜能干细胞的建立
Gao, Xuefei; Nowak-Imialek, Monika; Chen, Xi; Chen, Dongsheng; Herrmann, Doris; Ruan, Degong; Chen, Andy Chun Hang; Eckersley-Maslin, Melanie A.; Ahmad, Shakil; Lee, Yin Lau; Kobayashi, Toshihiro; Ryan, David; Zhong, Jixing; Zhu, Jiacheng; Wu, Jian; Lan, Guocheng; Petkov, Stoyan; Yang, Jian; Antunes, Liliana; Campos, Lia S.; Fu, Beiyuan; Wang, Shengpeng; Yong, Yu; Wang, Xiaomin; Xue, Song-Guo; Ge, Liangpeng; Liu, Zuohua; Huang, Yong; Nie, Tao; Li, Peng; Wu, Donghai; Pei, Duanqing; Zhang, Yi; Lu, Liming; Yang, Fengtang; Kimber, Susan J.; Reik, Wolf; Zou, Xiangang; Shang, Zhouchun; Lai, Liangxue; Surani, Azim; Tam, Patrick P. L.; Ahmed, Asif; Yeung, William Shu Biu; Teichmann, Sarah A.; Niemann, Heiner; Liu, Pentao
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收藏Possible detrimental effects of beta-2-microglobulin knockout in pigs
Sake, Hendrik Johannes; Frenzel, Antje; Lucas-Hahn, Andrea; Nowak-Imialek, Monika; Hassel, Petra; Hadeler, Klaus-Gerd; Hermann, Doris; Becker, Roswitha; Eylers, Heinke; Hein, Rabea; Baars, Wiebke; Brinkmann, Antje; Schwinzer, Reinhard; Niemann, Heiner; Petersen, Bjoern
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收藏Isolation of Human Xenospecific Regulatory T Cells with High Suppressive Function
Noyan, Fatih; Zimmermann, Katharina; Hardtke-Wolenski, Matthias; Mederacke, Young-Seon; Tenspolde, Michel; Petersen, Bjoem; Niemann, Heiner; Huehn, Jochen; Manns, Michael; Jaeckel, Elmar
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收藏Operational Tolerance in Xenotransplantation By Use of Regulatory T Cells with a SLA-specific Chimeric Antigen Receptor
Zimmermann, Katharina; Noyan, Fatih; Hust, Michael; Schwinzer, Reinhard; Hundrieser, Joachim; Hardtke-Wolenski, Matthias; Tenspolde, Michel; Petersen, Bjoern; Niemann, Heiner; Huehn, Jochen; Geffers, Robert; Manns, Michael; Jaeckel, Elmar
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收藏Successful knock-in of Hypertrophic Cardiomyopathy-mutation R723G into the MYH7 gene mimics HCM pathology in pigs
Montag, J.; Petersen, B.; Floegel, A. K.; Becker, E.; Lucas-Hahn, A.; Cost, G. J.; Muehlfeld, C.; Kraft, T.; Niemann, H.; Brenner, B.
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