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Autoreactive T cell receptors with shared germline-like α chains in type 1 diabetes (Vol 11, e207149, 2026) 1型糖尿病中具有共享种系样α链的自身反应性T细胞受体 (Vol 11, e207149, 2026) Linsley, Peter S.; Barahmand-pour-Whitman, Fariba; Balmas, Elisa; DeBerg, Hannah A.; Flynn, Kaitlin J.; Hu, Alex K.; Rosasco, Mario G.; Chen, Janice; O'Rourke, Colin; Serti, Elisavet; Gersuk, Vivian H.; Motwani, Keshav; Seay, Howard R.; Brusko, Todd M.; Kwok, William W.; Speake, Cate; Greenbaum, Carla J.; Nepom, Gerald T.; Cerosaletti, Karen 分享 收藏
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Two DRB3 residues predictively associate with the progression to type 1 diabetes among DR3 carriers 携带DR3的人群中,有两个DRB3残基能够预测性地与1型糖尿病的进展相关联。 Zhao, Lue Ping; Papadopoulos, George K.; Skyler, Jay S.; Kwok, William W.; Bondinas, George P.; Moustakas, Antonis K.; Wang, Ruihan; Pyo, Chul-Woo; Nelson, Wyatt C.; Geraghty, Daniel E. 分享 收藏
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Progression to type 1 diabetes in the DPT-1 and TN07 clinical trials is critically associated with specific residues in HLA-DQA1-B1 heterodimers 在DPT-1和TN07临床试验中进展为1型糖尿病与HLA-DQA1-B1异二聚体中的特定残基密切相关 Zhao, Lue Ping; Papadopoulos, George K.; Skyler, Jay S.; Pugliese, Alberto; Parikh, Hemang M.; Kwok, William W.; Lybrand, Terry P.; Bondinas, George P.; Moustakas, Antonis K.; Wang, Ruihan; Pyo, Chul-Woo; Nelson, Wyatt C.; Geraghty, Daniel E.; Lernmark, Ake 分享 收藏
Oral Insulin Delay of Stage 3 Type 1 Diabetes Revisited in HLA DR4-DQ8 Participants in the TrialNet Oral Insulin Prevention Trial (TN07) 在TrialNet口服胰岛素预防试验 (TN07) 的HLA DR4-DQ8参与者中重新研究了3期1型糖尿病的口服胰岛素延迟 Zhao, Lue Ping; Papadopoulos, George K.; Skyler, Jay S.; Parikh, Hemang M.; Kwok, William W.; Bondinas, George P.; Moustakas, Antonis K.; Wang, Ruihan; Pyo, Chul-Woo; Nelson, Wyatt C.; Geraghty, Daniel E.; Lernmark, Ake 分享 收藏
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HLA Class II (DR, DQ, DP) Genes Were Separately Associated With the Progression From Seroconversion to Onset of Type 1 Diabetes Among Participants in Two Diabetes Prevention Trials (DPT-1 and TN07) 在两项糖尿病预防试验 (DPT-1和TN07) 的参与者中,HLA II类 (DR,DQ,DP) 基因分别与从血清转化到1型糖尿病发作的进展相关。 Zhao, Lue Ping; Papadopoulos, George K.; Skyler, Jay S.; Pugliese, Alberto; Parikh, Hemang M.; Kwok, William W.; Lybrand, Terry P.; Bondinas, George P.; Moustakas, Antonis K.; Wang, Ruihan; Pyo, Chul-Woo; Nelson, Wyatt C.; Geraghty, Daniel E.; Lernmark, Ake 分享 收藏
Technical Validation and Utility of an HLA Class II Tetramer Assay for Type 1 Diabetes: A Multicenter Study Ettinger, Ruth A.; Buitinga, Mijke; Vandamme, Celine; Afonso, Georgia; Gomez, Rebecca; Arribas-Layton, David; Bissenova, Samal; Speake, Cate; Reijonen, Helena; Kinnunen, Tuure; Overbergh, Lut; Mallone, Roberto; Kwok, William W.; James, Eddie A. 分享 收藏
Distinct trajectories distinguish antigen-specific T cells in peanut-allergic individuals undergoing oral immunotherapy Calise, Justine; DeBerg, Hannah; Garabatos, Nahir; Khosa, Sugandhika; Bajzik, Veronique; Calderon, Lorena Botero; Aldridge, Kelly; Rosasco, Mario; Ferslew, Brian C.; Zhu, Tong; Smulders, Ronald; Wheatley, Lisa M.; Laidlaw, Tanya M.; Qin, Tielin; Chichili, Gurunadh R.; Adelman, Daniel C.; Farrington, Mary; Robinson, David; Jeong, David; Jones, Stacie M.; Sanda, Srinath; Larson, David; Kwok, William W.; Baloh, Carolyn; Nepom, Gerald T.; Wambre, Erik 分享 收藏
Evidence for broad cross-reactivity of the SARS-CoV-2 NSP12-directed CD4+ T-cell response with pre-primed responses directed against common cold coronaviruses Westphal, Tim; Mader, Maria; Karsten, Hendrik; Cords, Leon; Knapp, Maximilian; Schulte, Sophia; Hermanussen, Lennart; Peine, Sven; Ditt, Vanessa; Grifoni, Alba; Addo, Marylyn Martina; Huber, Samuel; Sette, Alessandro; Luetgehetmann, Marc; Pischke, Sven; Kwok, William W. W.; Sidney, John; Wiesch, Julian Schulze zur 分享 收藏
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A gut microbial peptide and molecular mimicry in the pathogenesis of type 1 diabetes Girdhar, Khyati; Huang, Qian; Chow, I. -Ting; Vatanen, Tommi; Brady, Claudia; Raisingani, Amol; Autissier, Patrick; Atkinson, Mark A.; Kwok, William W.; Kahn, C. Ronald; Altindis, Emrah 分享 收藏