Dena Lyras - Publications, H-index & Citations

Dena Lyras

monash university

52H指数

202论文数

1.0W被引数

收录论文 81

发表时间

A New Paradigm for Clostridioides difficile Infection: Atypical Presentations Correlating to Acute Gastrointestinal Dysmotility Are Associated With Increased Mortality 艰难梭菌感染的新范式：与急性胃肠道运动障碍相关的非典型表现与死亡率增加有关

Clinical Infectious Diseases

IF7.3

2026-08-25

OAAI

Emma Bishop; Steven Mileto; Tanya Ravipati; Nazim Bhimani; Eugene Athan; Ravindranath Tiruvoipati; Dena Lyras; null

Uncovering an alternate pathway of antibiotic resistance in spore-forming bacteria 揭示芽孢形成细菌中抗生素耐药性的替代途径

Nature Communications

IF15.7

2026-07-15

OAAI

Yogitha N. Srikhanta; Clara E. Bate; Desirel Ng; Sarah A. Revitt-Mills; Georgia-Rose Gilmore; Galain C. Williams; Sophie L. Day; Stéphane Mesnage; Kamila Kochan; Shailab Shrestha; Aimee Shen; Daniel R. Knight; Korakrit Imwattana; Thomas V. Riley; Irene Alevizos; Kimberley Bourke; Milena M. Awad; Caroline A. Evans; Ghizal Siddiqui; Joel R. Steele; David L. Steer; Joshua P. Morrow; Darren J. Creek; Chaille Webb; Sheena McGowan; Dena Lyras

Pathogen species and capsule expression shape opportunistic transfer and the recipient response during plasmid RP4 conjugation 病原体种类和荚膜表达塑造质粒RP4接合过程中的机会性转移及受体响应

Communications Biology

IF5.1

2026-05-27

OAAI

Galain C. Williams; Jillian C. Danne; Simon Crawford; Jihane Homman-Ludiye; Xenia Kostoulias; Bailey Heron; Tasnia Islam; Melvin Yong; Yunn-Hwen Gan; Yogitha N. Srikhanta; Dena Lyras

Differential gut transmission of IncP plasmid clades involving hypervirulent Klebsiella pneumoniae reveals plasmid-specific ecological adaptation IncP质粒谱系在超毒力肺炎克雷伯菌中的肠道差异传播揭示了质粒特异性的生态适应

Nature Communications

IF15.7

2025-12-10

OAAI

Melvin Yong; Wen Wen Low; Swapnil Mishra; Galain Williams; Steven Mileto; Carey Lim; Channe Chwa; Guodong Oo; Guoxiang Cheam; Yahua Chen; Hao Chung The; Thanh Duy Pham; Dena Lyras; Yunn-Hwen Gan

A widespread hydrogenase supports fermentative growth of gut bacteria in healthy people 一种广泛存在的氢化酶支持健康人群肠道细菌的发酵生长

Nature Microbiology

IF19.4

2025-10-23

OAAI

Caitlin Welsh; Princess R. Cabotaje; Vanessa R. Marcelino; Thomas D. Watts; Duncan J. Kountz; Marion Jespersen; Jodee A. Gould; Nhu Quynh Doan; James P. Lingford; Thilini Koralegedara; Jessica Solari; Gemma L. D’Adamo; Ping Huang; Natasha Bong; Emily L. Gulliver; Remy B. Young; Henrik Land; Kaija Walter; Isaac Cann; Gabriel V. Pereira; Eric C. Martens; Patricia G. Wolf; Jason M. Ridlon; H. Rex Gaskins; Edward M. Giles; Dena Lyras; Rachael Lappan; Gustav Berggren; Samuel C. Forster; Chris Greening

Isolation, engineering and ecology of temperate phages from the human gut 从人类肠道中分离、工程改造和生态学研究温和噬菌体

Nature

IF48.5

2025-10-15

OAAI

Sofia Dahlman; Laura Avellaneda-Franco; Emily L. Rutten; Emily L. Gulliver; Sean Solari; Michelle Chonwerawong; Ciaren Kett; Dinesh Subedi; Remy B. Young; Nathan Campbell; Jodee A. Gould; Jasmine D. Bell; Callum A. H. Docherty; Christopher J. R. Turkington; Neda Nezam-Abadi; Juris A. Grasis; Dena Lyras; Robert A. Edwards; Samuel C. Forster; Jeremy J. Barr

Clostridioides difficile should be considered a bacterial priority pathogen 艰难梭菌（Clostridioides difficile）应被视为一种细菌性优先病原体。

lancet microbe

IF0

2025-06-01

OAAI

Wiep Klaas Smits; Kevin W Garey; Thomas V Riley; Yiping W Han; Vincent B Young; John Heritage; Christian John Lillis; Dena Lyras; Maja Rupnik; Stuart Johnson

Mechanisms of blaIMP-4 dissemination across diverse carbapenem-resistant clinical isolates

JOURNAL OF GLOBAL ANTIMICROBIAL RESISTANCE

IF3.2

2025-03-01

OAAI

Fu, Ying; Morris, Faye C.; Pereira, Stephanie C.; Kostoulias, Xenia; Jiang, Yan; Vidor, Callum; Williams, Galain; Srikhanta, Yogi; Macesic, Nenad; Yu, Yunsong; Lyras, Dena; Peleg, Anton Y.

A Multimodal Spectroscopic Approach Combining Mid-infrared and Near-infrared for Discriminating Gram-positive and Gram-negative Bacteria

ANALYTICAL CHEMISTRY

IF6.7

2024-11-04

PREAI

Veettil, Thulya Chakkumpulakkal Puthan; Kochan, Kamila; Williams, Galain C.; Bourke, Kimberley; Kostoulias, Xenia; Peleg, Anton Y.; Lyras, Dena; De Bank, Paul A.; Perez-Guaita, David; Wood, Bayden R.

Towards integrated cross-sectoral surveillance of pathogens and antimicrobial resistance: Needs, approaches, and considerations for linking surveillance to action 迈向病原体和抗菌素耐药性的综合跨部门监测: 将监测与行动联系起来的需求，方法和考虑因素

ENVIRONMENT INTERNATIONAL

IF9.7

2024-10-01

OAAI

Lappan, Rachael; Chown, Steven L.; French, Matthew; Perlaza-Jimenez, Laura; Macesic, Nenad; Davis, Mark; Brown, Rebekah; Cheng, Allen; Clasen, Thomas; Conlan, Lindus; Goddard, Frederick; Henry, Rebekah; Knight, Daniel R.; Li, Fuyi; Luby, Stephen; Lyras, Dena; Ni, Gaofeng; Rice, Scott A.; Short, Francesca; Song, Jiangning; Whittaker, Andrea; Leder, Karin; Lithgow, Trevor; Greening, Chris

A Clostridioides difficile endolysin modulates toxin secretion without cell lysis

COMMUNICATIONS BIOLOGY

IF5.1

2024-08-23

OAAI

Awad, Milena M.; Suraweera, Chathura D.; Vidor, Callum J.; Ye-Lin, Auberon Y.; Williams, Galain C.; Mileto, Steven J.; Barlow, Christopher K.; McGowan, Sheena; Lyras, Dena

Design, Synthesis, and Evaluation of Cephamycin-Based Antisporulation Agents targeting Clostridioides difficile

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2023-12-19

PREAI

Cun, Wendy Y.; Bate, Clara E.; Srikhanta, Yogitha N.; Hutton, Melanie L.; Webb, Chaille T.; Revitt-Mills, Sarah A.; Lyras, Dena; McGowan, Sheena; Yu, Haibo; Keller, Paul A.; Pyne, Stephen G.

A genomic survey of Clostridioides difficile isolates from hospitalized patients in Melbourne, Australia

MICROBIOLOGY SPECTRUM

IF3.8

2023-12-12

OAAI

Larcombe, Sarah; Williams, Galain C.; Amy, Jacob; Lim, Su Chen; Riley, Thomas V.; Muleta, Anthony; Barugahare, Adele A.; Powell, David R.; Johanesen, Priscilla A.; Cheng, Allen C.; Peleg, Anton Y.; Lyras, Dena

Multi-omics analysis of hospital-acquired diarrhoeal patients reveals biomarkers of enterococcal proliferation and Clostridioides difficile infection

NATURE COMMUNICATIONS

IF15.7

2023-11-25

OAAI

Bosnjak, Marijana; Karpe, Avinash V.; Van, Thi Thu Hao; Kotsanas, Despina; Jenkin, Grant A.; Costello, Samuel P.; Johanesen, Priscilla; Moore, Robert J.; Beale, David J.; Srikhanta, Yogitha N.; Palombo, Enzo A.; Larcombe, Sarah; Lyras, Dena

Antihypertensives and Antibiotics: Impact on Intestinal Dysfunction and Hypertension

HYPERTENSION

IF8.2

2023-07-01

PREAI

Lucas, Sarah E.; Walton, Sarah L.; Colafella, Katrina M. Mirabito M.; Mileto, Steven J.; Lyras, Dena; Denton, Kate M.

Clostridium perfringens virulence factors are nonredundant activators of the NLRP3 inflammasome 产气荚膜梭菌毒力因子是NLRP3炎性体的非冗余激活剂

EMBO REPORTS

IF6.2

2023-04-19

OAAI

Mathur, Anukriti; Kay, Callum; Xue, Yansong; Pandey, Abhimanu; Lee, Jiwon; Jing, Weidong; Tuipulotu, Daniel Enosi; Lo Pilato, Jordan; Feng, Shouya; Ngo, Chinh; Zhao, Anyang; Shen, Cheng; Rug, Melanie; Miosge, Lisa A.; Atmosukarto, Ines I.; Price, Jason D.; Ali, Sidra A.; Gardiner, Elizabeth E.; Robertson, Avril A. B.; Awad, Milena M.; Lyras, Dena; Kaakoush, Nadeem O.; Man, Si Ming

Impact of enteric bacterial infections at and beyond the epithelial barrier 肠道细菌感染在上皮屏障和上皮屏障之外的影响

NATURE REVIEWS MICROBIOLOGY

IF103.3

2022-09-29

PREAI

Rogers, Ashleigh P.; Mileto, Steven J.; Lyras, Dena

A lipoglycopeptide antibiotic for Gram-positive biofilm-related infections

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2022-09-14

PREAI

Blaskovich, Mark A. T.; Hansford, Karl A.; Butler, Mark S.; Ramu, Soumya; Kavanagh, Angela M.; Jarrad, Angie M.; Prasetyoputri, Anggia; Pitt, Miranda E.; Huang, Johnny X.; Lindahl, Fredrik; Ziora, Zyta M.; Bradford, Tanya; Muldoon, Craig; Rajaratnam, Premraj; Pelingon, Ruby; Edwards, David J.; Zhang, Bing; Amado, Maite; Elliott, Alysha G.; Zuegg, Johannes; Coin, Lachlan; Woischnig, Anne-Kathrin; Khanna, Nina; Breidenstein, Elena; Stincone, Anna; Mason, Clive; Khan, Nawaz; Cho, Hye-Kyung; Karau, Melissa J.; Greenwood-Quaintance, Kerryl E.; Patel, Robin; Wootton, Mandy; James, Meagan L.; Hutton, Melanie L.; Lyras, Dena; Ogunniyi, Abiodun D.; Mahdi, Layla K.; Trott, Darren J.; Wu, Xiaoqian; Niles, Samantha; Lewis, Kim; Smith, Jordan R.; Barber, Katie E.; Yim, Juwon; Rice, Seth Alan; Rybak, Michael J.; Ishmael, Chad R.; Hori, Kellyn R.; Bernthal, Nicholas M.; Francis, Kevin P.; Roberts, Jason A.; Paterson, David L.; Cooper, Matthew A.

Bezlotoxumab prevents extraintestinal organ damage induced by Clostridioides difficile infection

GUT MICROBES

IF11

2022-08-31

OAAI

Mileto, Steven J.; Hutton, Melanie L.; Walton, Sarah L.; Das, Antariksh; Ioannidis, Lisa J.; Ketagoda, Don; Quinn, Kylie M.; Denton, Kate M.; Hansen, Diana S.; Lyras, Dena

Clostridium septicum α-toxin activates the NLRP3 inflammasome by engaging GPI-anchored proteins

SCIENCE IMMUNOLOGY

IF16.3

2022-05-27

OAAI

Jing, Weidong; Lo Pilato, Jordan; Kay, Callum; Feng, Shouya; Tuipulotu, Daniel Enosi; Mathur, Anukriti; Shen, Cheng; Ngo, Chinh; Zhao, Anyang; Miosge, Lisa A.; Ali, Sidra A.; Gardiner, Elizabeth E.; Awad, Milena M.; Lyras, Dena; Robertson, Avril A. B.; Kaakoush, Nadeem O.; Man, Si Ming

研究方向