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Trametinib sensitizes KRAS-mutant lung adenocarcinoma tumors to PD-1/PD-L1 axis blockade via Id1 downregulation 曲美替尼通过Id1下调使KRAS突变型肺腺癌肿瘤对PD-1/PD-L1轴阻滞敏感 Puyalto, Ander; Rodriguez-Remirez, Maria; Lopez, Ines; Macaya, Irati; Guruceaga, Elizabeth; Olmedo, Maria; Vilalta-Lacarra, Anna; Welch, Connor; Sandiego, Sergio; Vicent, Silvestre; Valencia, Karmele; Calvo, Alfonso; Pio, Ruben; Raez, Luis E.; Rolfo, Christian; Ajona, Daniel; Gil-Bazo, Ignacio 分享 收藏
Whole exome sequencing and machine learning germline analysis of individuals presenting with extreme phenotypes of high and low risk of developing tobacco-associated lung adenocarcinoma Patino-Garcia, Ana; Guruceaga, Elizabeth; Andueza, Maria Pilar; Ocon, Marimar; Sokoudjou, Jafait Junior Fodop; Zornoza, Nicolas de Villalonga; Alkorta-Aranburu, Gorka; Uria, Ibon Tamayo; Gurpide, Alfonso; Camps, Carlos; Jantus-Lewintre, Eloisa; Navamuel-Andueza, Maria; Sanmamed, Miguel F.; Melero, Ignacio; Elgendy, Mohamed; Fusco, Juan Pablo; Zulueta, Javier J.; de-Torres, Juan P.; Bastarrika, Gorka; Seijo, Luis; Pio, Ruben; Montuenga, Luis M.; Hernaez, Mikel; Ochoa, Idoia; Perez-Gracia, Jose Luis 分享 收藏
The oncolytic adenovirus Delta-24-RGD in combination with ONC201 induces a potent antitumor response in pediatric high-grade and diffuse midline glioma models 溶瘤腺病毒Delta-24-RGD与ONC201联合在小儿高级别和弥漫性中线胶质瘤模型中诱导有效的抗肿瘤反应 de la Nava, Daniel; Ausejo-Mauleon, Iker; Laspidea, Virginia; Gonzalez-Huarriz, Marisol; Lacalle, Andrea; Casares, Noelia; Zalacain, Marta; Marrodan, Lucia; Garcia-Moure, Marc; Ochoa, Maria C.; Tallon-Cobos, Antonio Carlos; Hernandez-Osuna, Reyes; Marco-Sanz, Javier; Dhandapani, Laasya; Hervas-Corpion, Irati; Becher, Oren J.; Nazarian, Javad; Mueller, Sabine; Phoenix, Timothy N.; van der Lugt, Jasper; Hernaez, Mikel; Guruceaga, Elizabeth; Koschmann, Carl; Venneti, Sriram; Allen, Joshua E.; Dun, Matthew D.; Fueyo, Juan; Gomez-Manzano, Candelaria; Perez-Larraya, Jaime Gallego; Patino-Garcia, Ana; Labiano, Sara; Alonso, Marta M. 分享 收藏
Signature-driven repurposing of Midostaurin for combination with MEK1/2 and KRASG12C inhibitors in lung cancer Macaya, Irati; Roman, Marta; Welch, Connor; Entrialgo-Cadierno, Rodrigo; Salmon, Marina; Santos, Alba; Feliu, Iker; Kovalski, Joanna; Lopez, Ines; Rodriguez-Remirez, Maria; Palomino-Echeverria, Sara; Lonfgren, Shane M.; Ferrero, Macarena; Calabuig, Silvia; Ludwig, Iziar A.; Lara-Astiaso, David; Jantus-Lewintre, Eloisa; Guruceaga, Elizabeth; Narayanan, Shruthi; Ponz-Sarvise, Mariano; Pineda-Lucena, Antonio; Lecanda, Fernando; Ruggero, Davide; Khatri, Purvesh; Santamaria, Enrique; Fernandez-Irigoyen, Joaquin; Ferrer, Irene; Paz-Ares, Luis; Drosten, Matthias; Barbacid, Mariano; Gil-Bazo, Ignacio; Vicent, Silve 分享 收藏
The phospholipid transporter PITPNC1 links KRAS to MYC to prevent autophagy in lung and pancreatic cancer (vol 22, 86, 2023) Entrialgo-Cadierno, Rodrigo; Cueto-Urena, Cristina; Welch, Connor; Feliu, Iker; Macaya, Irati; Vera, Laura; Morales, Xabier; Michelina, Sandra Vietti; Scaparone, Pietro; Lopez, Ines; Darbo, Elodie; Erice, Oihane; Vallejo, Adrian; Moreno, Haritz; Goni-Salaverri, Ainhoa; Lara-Astiaso, David; Halberg, Nils; Cortes-Dominguez, Ivan; Guruceaga, Elizabeth; Ambrogio, Chiara; Lecanda, Fernando; Vicent, Silve 分享 收藏
The phospholipid transporter PITPNC1 links KRAS to MYC to prevent autophagy in lung and pancreatic cancer 磷脂转运蛋白PITPNC1将KRAS与MYC连接以防止肺癌和胰腺癌中的自噬 Entrialgo-Cadierno, Rodrigo; Cueto-Urena, Cristina; Welch, Connor; Feliu, Iker; Macaya, Irati; Vera, Laura; Morales, Xabier; Michelina, Sandra Vietti; Scaparone, Pietro; Lopez, Ines; Darbo, Elodie; Erice, Oihane; Vallejo, Adrian; Moreno, Haritz; Goni-Salaverri, Ainhoa; Lara-Astiaso, David; Halberg, Nils; Cortes-Dominguez, Ivan; Guruceaga, Elizabeth; Ambrogio, Chiara; Lecanda, Fernando; Vicent, Silve 分享 收藏
LAMC2 Regulates Key Transcriptional and Targetable Effectors to Support Pancreatic Cancer Growth Erice, Oihane; Narayanan, Shruthi; Feliu, Iker; Entrialgo-Cadierno, Rodrigo; Malinova, Antonia; Vicentini, Caterina; Guruceaga, Elizabeth; No, Pietro Del fi; Trajkovic-Arsic, Marija; Moreno, Haritz; Valencia, Karmele; Blanco, Ester; Macaya, Irati; Ohlund, Daniel; Khatri, Purvesh; Lecanda, Fernando; Scarpa, Aldo; Siveke, Jens T.; Corbo, Vincenzo; Ponz-Sarvise, Mariano; Vicent, Silve 分享 收藏
Gemcitabine-mediated depletion of immunosuppressive dendritic cells enhances the efficacy of therapeutic vaccination Reparaz, David; Ruiz, Marta; Silva, Leyre; Aparicio, Belen; Egea, Josune; Guruceaga, Elizabeth; Ajona, Daniel; Senent, Yaiza; Conde, Enrique; Navarro, Flor; Barace, Sergio; Alignani, Diego; Hervas-Stubbs, Sandra; Jose Lasarte, Juan; Llopiz, Diana; Sarobe, Pablo 分享 收藏
A weight-loss model based on baseline microbiota and genetic scores for selection of dietary treatments in overweight and obese Cuevas-Sierra, Amanda; Milagro, Fermin, I; Guruceaga, Elizabeth; Cuervo, Marta; Goni, Leticia; Garcia-Granero, Marta; Alfredo Martinez, J.; Riezu-Boj, Jose, I 分享 收藏
The bone marrow niche regulates redox and energy balance in MLL::AF9 leukemia stem cells Vinado, Ana C.; Calvo, Isabel A.; Cenzano, Itziar; Olaverri, Danel; Cocera, Miguel; San Martin-Uriz, Patxi; Romero, Juan P.; Vilas-Zornoza, Amaia; Vera, Laura; Gomez-Cebrian, Nuria; Puchades-Carrasco, Leonor; Lisi-Vega, Livia E.; Apaolaza, Inigo; Valera, Pablo; Guruceaga, Elisabeth; Granero-Molto, Froilan; Ripalda-Cemborain, Purificacion; Luck, Tamara J.; Bullinger, Lars; Planes, Francisco J.; Rifon, Jose J.; Mendez-Ferrer, Simon; Yusuf, Rushdia Z.; Pardo-Saganta, Ana; Prosper, Felipe; Saez, Borja 分享 收藏
Exploiting 4-1BB immune checkpoint to enhance the efficacy of oncolytic virotherapy for diffuse intrinsic pontine gliomas Laspidea, Virginia; Puigdelloses, Montserrat; Labiano, Sara; Marrodan, Lucia; Garcia-Moure, Marc; Zalacain, Marta; Gonzalez-Huarriz, Marisol; Martinez-Velez, Naiara; Ausejo-Mauleon, Iker; de la Nava, Daniel; Herrador-Canete, Guillermo; Marco-Sanz, Javier; Guruceaga, Elisabeth; de Andrea, Carlos E.; Villalba, Maria; Becher, Oren; Squatrito, Massimo; Matia, Veronica; Gallego Perez-Larraya, Jaime; Patino-Garcia, Ana; Gupta, Sumit; Gomez-Manzano, Candelaria; Fueyo, Juan; Alonso, Marta M. 分享 收藏
Tumor ENPP1 (CD203a)/Haptoglobin Axis Exploits Myeloid-Derived Suppressor Cells to Promote Post-Radiotherapy Local Recurrence in Breast Cancer Ruiz-Fernandez de Cordoba, Borja; Moreno, Haritz; Valencia, Karmele; Perurena, Naiara; Ruedas, Pablo; Walle, Thomas; Pezonaga-Torres, Alberto; Hinojosa, Juan; Guruceaga, Elisabet; Pineda-Lucena, Antonio; Abengozar-Muela, Marta; Cochonneau, Denis; Zandueta, Carolina; Martinez-Canarias, Susana; Teijeira, Alvaro; Ajona, Daniel; Ortiz-Espinosa, Sergio; Morales, Xabier; Ortiz de Solorzano, Carlos; Santisteban, Marta; Ramos-Garcia, Luis, I; Guembe, Laura; Strnad, Vratislav; Heymann, Dominique; Hervas-Stubbs, Sandra; Pio, Ruben; Rodriguez-Ruiz, Maria E.; de Andrea, Carlos E.; Vicent, Silvestre; Melero, Ignacio; Lecanda, Fernando; Martinez-Monge, Rafael 分享 收藏
FOSL1 promotes cholangiocarcinoma via transcriptional effectors that could be therapeutically targeted Vallejo, Adrian; Erice, Oihane; Entrialgo-Cadierno, Rodrigo; Feliu, Iker; Guruceaga, Elizabeth; Perugorria, Maria J.; Olaizola, Paula; Muggli, Alexandra; Macaya, Irati; O'Dell, Michael; Ruiz-Fernandez De Cordoba, Borja; Ortiz-Espinosa, Sergio; Hezel, Aram F.; Arozarena, Imanol; Lecanda, Fernando; Avila, Matias A.; Fernandez-Barrena, Maite G.; Evert, Matthias; Ponz-Sarvise, Mariano; Calvisi, Diego F.; Banales, Jesus M.; Vicent, Silve 分享 收藏
The Transcription Factor SLUG Uncouples Pancreatic Cancer Progression from the RAF-MEK1/2-ERK1/2 Pathway Bilal, Faiz; Arenas, Enrique J.; Pedersen, Kim; Martinez-Sabadell, Alex; Nabet, Behnam; Guruceaga, Elizabeth; Vicent, Silvestre; Tabernero, Josep; Macarulla, Teresa; Arribas, Joaquin 分享 收藏
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